Molekulare Zellbiologie 1
- Beziehungen:
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- Centrins in retinal photoreceptor cells:: Regulators in the connecting cilium
- Characterization of the epithelial permeation enhancing effect of basic Butylated methacrylate copolymer - in vitro studies
- Photoreceptor vitality in organotypic cultures of mature vertebrate retinas validated by light-dependent molecular movements
- Crystallization and preliminary X-ray studies of mouse centrin1
- Differential expression and interaction with the visual G-protein transducin of centrin isoforms in mammalian photoreceptor cells
- Impaired formation of the inner retina in an AChE knockout mouse results in degeneration of all photoreceptors
- Interaction of glutamic-acid-rich proteins with the cGMP signalling pathway in rod photoreceptors
- Expression of centrin isoforms in the mammalian retina
- CYTOSKELETAL ELEMENTS IN ARTHROPOD SENSILLA AND MAMMALIAN PHOTORECEPTORS
- Isolation of genes encoding photoreceptor-specific proteins by immunoscreening with antibodies directed against purified blowfly rhabdoms
- CENTRIN-LIKE AND ALPHA-ACTININ-LIKE IMMUNOREACTIVITY IN THE CILIARY ROOTLETS OF INSECT SENSILLA
- TROPOMYOSIN IS CO-LOCALIZED WITH THE ACTIN-FILAMENTS OF THE SCOLOPALE IN INSECT SENSILLA
- DISTRIBUTION OF F-ACTIN IN THE COMPOUND EYE OF THE BLOWFLY, CALLIPHORA-ERYTHROCEPHALA (DIPTERA, INSECTA)
- ACTIN-FILAMENTS - THE MAIN COMPONENTS OF THE SCOLOPALE IN INSECT SENSILLA
- Pathogenic Variants in USH1G/SANS Alter Protein Interaction with Pre-RNA Processing Factors PRPF6 and PRPF31 of the Spliceosome
- Pathogenic Variants in USH1G/SANS Alter the Protein Interaction With the Pre-RNA Processing Factors PRPF6 and PRPF31 of the Spliceosome
- The Leber Congenital Amaurosis Protein AIPL1 and EB Proteins Co-Localize at the Photoreceptor Cilium
- Immunoelectron Microscopy of Vesicle Transport to the Primary Cilium of Photoreceptor Cells
- Caki-1 cells represent an in vitro model system for studying the human proximal tubule epithelium
- Efficient gene delivery to photoreceptors using AAV2/rh10 and rescue of the Rho-/- mouse
- Successful Subretinal Delivery and Monitoring of MicroBeads in Mice
- Intravitreal delivery of AAV-NDI1 provides functional benefit in a murine model of Leber hereditary optic neuropathy
- Gene repair of an Usher syndrome causing mutation by zinc-finger nuclease mediated homologous recombination
- Iron oxide/hydroxide nanoparticles with negatively charged shells show Increased uptake in caco-2 cells
- Nxnl2 splicing results in dual functions in neuronal cell survival and maintenance of cell integrity
- Hemin-coupled iron(III)-hydroxide nanoparticles show increased uptake in Caco-2 cells
- Direct interaction of the Usher syndrome 1G protein SANS and myomegalin in the retina
- PTC124-Mediated Translational Readthrough of a Nonsense Mutation Causing Usher Syndrome Type 1C
- Modification of the major tegument protein pp65 of human cytomegalovirus inhibits virus growth and leads to the enhancement of a protein complex with pUL69 and pUL97 in infected cells
- Polyglutamine toxicity induces rod photoreceptor division, morphological transformation or death in Spinocerebellar ataxia 7 mouse retina
- Optimized recombinant dense bodies of human cytomegalovirus efficiently prime virus specific lymphocytes and neutralizing antibodies without the addition of adjuvant
- Bone spicule pigment formation in retinitis pigmentosa: insights from a mouse model
- Adeno-Associated Virus-Mediated Rhodopsin Replacement Provides Therapeutic Benefit in Mice with a Targeted Disruption of the Rhodopsin Gene
- Light-dependent translocation of arrestin in rod photoreceptors is signaled through a phospholipase C cascade and requires ATP
- Different Roles for KIF17 and Kinesin II in Photoreceptor Development and Maintenance
- Vezatin, a ubiquitous protein of adherens cell-cell junctions, is exclusively expressed in germ cells in mouse testis
- The ARF GAPs ELMOD1 and ELMOD3 act at the Golgi and cilia to regulate ciliogenesis and ciliary protein traffic
- PRCD is concentrated at the base of photoreceptor outer segments and is involved in outer segment disc formation
- Peripherin-2 differentially interacts with cone opsins in outer segments of cone photoreceptors
- Targeting Nonsense Mutations in Diseases with Translational Read-Through-Inducing Drugs (TRIDs)
- Impact of the Usher syndrome on olfaction
- The GTP- and Phospholipid-Binding Protein TTD14 Regulates Trafficking of the TRPL Ion Channel in Drosophila Photoreceptor Cells
- Deletion of myosin VI causes slow retinal optic neuropathy and age-related macular degeneration (AMD)-relevant retinal phenotype
- TALPID3 controls centrosome and cell polarity and the human ortholog KIAA0586 is mutated in Joubert syndrome (JBTS23)
- A novel function of Huntingtin in the cilium and retinal ciliopathy in Huntington's disease mice
- Estrogen receptor α regulates non-canonical autophagy that provides stress resistance to neuroblastoma and breast cancer cells and involves BAG3 function
- Therapy Strategies for Usher Syndrome Type 1C in the Retina
- New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors
- Peripherin-2 couples rhodopsin to the CNG channel in outer segments of rod photoreceptors
- Disruption of the retinitis pigmentosa 28 gene Fam161a in mice affects photoreceptor ciliary structure and leads to progressive retinal degeneration
- Translational read-through as an alternative approach for ocular gene therapy of retinal dystrophies caused by in-frame nonsense mutations
- Mutation of POC1B in a Severe Syndromic Retinal Ciliopathy
- Phosphorylation of the Usher syndrome 1G protein SANS controls Magi2-mediated endocytosis
- Light-dependent phosphorylation of Bardet-Biedl syndrome 5 in photoreceptor cells modulates its interaction with arrestin1
- The giant spectrin V couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route
- Vesicle Transport and Photoreceptor Death: Fishing for Molecular Links
- Transcriptional analysis of rat photoreceptor cells reveals daily regulation of genes important for visual signaling and light damage susceptibility
- The Adhesion G-Protein-Coupled Receptor GPR115/ADGRF4 Regulates Epidermal Differentiation and Associates with Cytoskeletal KRT1
- Refinement of strategies for the development of a human cytomegalovirus dense body vaccine
- SANS (USH1G) expression in developing and mature mammalian retina
- Exogenous introduction of an immunodominant peptide from the non-structural IE1 protein of human cytomegalovirus into the MHC class I presentation pathway by recombinant dense bodies
- MPP1 links the Usher protein network and the Crumbs protein complex in the retina
- Mutations in the gene encoding the basal body protein RPGRIP1L, a nephrocystin-4 interactor, cause Joubert syndrome
- Centrins, gatekeepers for the light-dependent translocation of transducin through the photoreceptor cell connecting cilium
- Insights into functional aspects of centrins from the structure of N-terminally extended mouse centrin 1
- Molecular basis of human Usher syndrome:: Deciphering the meshes of the Usher protein network provides insights into the pathomechanisms of the Usher disease
- Differential distribution of harmonin isoforms and their possible role in Usher-1 protein complexes in mammalian photoreceptor cells
- Calcium-dependent assembly of centrin-G-protein complex in photoreceptor cells
- The role of cadherins in Ca2+-mediated cell adhesion and inherited photoreceptor degeneration
- Identification of novel molecular components of the photoreceptor connecting cilium by immunoscreens
- Effects of Presynaptic Mutations on a Postsynaptic Cacna1s Calcium Channel Colocalized with mGluR6 at Mouse Photoreceptor Ribbon Synapses
- Usher syndrome and Leber congenital amaurosis are molecularly linked via a novel isoform of the centrosomal ninein-like protein
- The translocation of signaling molecules in dark adapting mammalian rod photoreceptor cells is dependent on the cytoskeleton
- Light-dependent CK2-mediated phosphorylation of centrins regulates complex formation with visual G-protein
- Myosin VIIa as a common component of cilia and microvilli
- Dephosphorylation of Centrins by Protein Phosphatase 2C and
- A novel pyruvate kinase (PK-S) from boar spermatozoa is localized at the fibrous sheath and the acrosome
- Molecular analysis of the supramolecular usher protein complex in the retina. Harmonin as the key protein of the Usher syndrome.
- The Retinal Clock Drives the Expression of Kcnv2, a Channel Essential for Visual Function and Cone Survival
- Expression and compartmentalisation of the glycolytic enzymes GAPDH and pyruvate kinase in boar spermatogenesis
- Homozygous disruption of PDZD7 by reciprocal translocation in a consanguineous family: a new member of the Usher syndrome protein interactome causing congenital hearing impairment
- The mitotic spindle protein SPAG5/Astrin connects to the Usher protein network postmitotically
- A Homozygous Mutation in the TUB Gene Associated with Retinal Dystrophy and Obesity
- Dissecting signaling and functions of adhesion G protein-coupled receptors
- The retinitis pigmentosa protein RP2 links pericentriolar vesicle transport between the Golgi and the primary cilium
- Occurrence of Retinal Ganglion Cell Loss via Autophagy and Apoptotic Pathways in an Autoimmune Glaucoma Model
- Usher syndrome:: molecular links of pathogenesis, proteins and pathways
- The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1
- The SYSCILIA gold standard (SCGSv1) of known ciliary components and its applications within a systems biology consortium
- TOPORS, implicated in retinal degeneration, is a cilia-centrosomal protein
- Autophagy interferes with human cytomegalovirus genome replication, morphogenesis, and progeny release
- CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination
- The cellular function of the Usher gene product myosin VIIa is specified by its ligands
- Molecular cloning of Drosophila Rh6 rhodopsin: The visual pigment of a subset of R8 photoreceptor cells
- Roles for ELMOD2 and Rootletin in ciliogenesis
- C21orf2 is mutated in recessive early-onset retinal dystrophy with macular staphyloma and encodes a protein that localises to the photoreceptor primary cilium
- A comparative evaluation of NB30, NB54 and PTC124 in translational read-through efficacy for treatment of an USH1C nonsense mutation
- Suppression and Replacement Gene Therapy for Autosomal Dominant Disease in a Murine Model of Dominant Retinitis Pigmentosa
- Biallelic Variants in TTLL5, Encoding a Tubulin Glutamylase, Cause Retinal Dystrophy
- Interactions in the network of Usher syndrome type 1 proteins
- A new mouse model for retinal degeneration due to Fam161a deficiency
- Multifunctional superparamagnetic MnO@SiO2 core/shell nanoparticles and their application for optical and magnetic resonance imaging
- MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomes
- A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth
- Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle
- Beneficial Read-Through of a USH1C Nonsense Mutation by Designed Aminoglycoside NB30 in the Retina
- Germline deletion of Cetn1 causes infertility in male mice
- A key role for cyclic nucleotide gated (CNG) channels in cGMP-related retinitis pigmentosa
- The retinitis pigmentosa 28 protein FAM161A is a novel ciliary protein involved in intermolecular protein interaction and microtubule association
- Protein Networks and Complexes in Photoreceptor Cilia
- Molecular Analysis of the Supramolecular Usher Protein Complex in the Retina
- Centrins, Potential Regulators of Transducin Translocation in Photoreceptor Cells
- Translational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells
- Usher Syndrome Protein Network Functions in the Retina and their Relation to Other Retinal Ciliopathies
- Intraflagellar transport proteins in ciliogenesis of photoreceptor cells
- CiliaCarta: An integrated and validated compendium of ciliary genes
- PEX6 is Expressed in Photoreceptor Cilia and Mutated in Deafblindness with Enamel Dysplasia and Microcephaly
- An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes
- A novel Usher protein network at the periciliary reloading point between molecular transport machineries in vertebrate photoreceptor cells
- Mutations in LCA5, encoding the ciliary protein lebercilin, cause Leber congenital amaurosis
- CENTRIN IN THE PHOTORECEPTOR CELLS OF MAMMALIAN RETINAE
- Rhodopsin transport in the membrane of the connecting cilium of mammalian photoreceptor cells
- Myosin VIIa as a common component of cilia and microvilli
- Usherin defects lead to early-onset retinal dysfunction in zebrafish
- Adenovirus E1A/E1B transformed amniotic fluid cells support human cytomegalovirus replication
- KIAA0556 is a novel ciliary basal body component mutated in Joubert syndrome
- Septins 2, 7 and 9 and MAP4 colocalize along the axoneme in the primary cilium and control ciliary length
- BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins
- Intraflagellar transport molecules in ciliary and nonciliary cells of the retina
- Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3
- Active zone proteins are dynamically associated with synaptic ribbons in rat pinealocytes
- International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein-Coupled Receptors
- Mutations in ARL2BP, Encoding ADP-Ribosylation-Factor-Like 2 Binding Protein, Cause Autosomal-Recessive Retinitis Pigmentosa
- How does the eye breathe? Evidence for neuroglobin-mediated oxygen supply in the mammalian retina
- Vezatin, a novel transmembrane protein, bridges myosin VIIA to the cadherin-catenins complex
- Rhodopsin’s carboxy-terminal cytoplasmic tail acts as a membrane receptor for cytoplasmic dynein by binding to the dynein light chain Tctex-1
- Cadherin 23 is a component of the transient lateral links in the developing hair bundles of cochlear sensory cells
- Divergent distribution in vascular and avascular mammalian retinae links neuroglobin to cellular respiration
- RPGR ORF15 isoform co-localizes with RPGRIP1 at centrioles and basal bodies and interacts with nucleophosmin
- Myosin VIIa, the product of the Usher 1B syndrome gene, is concentrated in the connecting cilia of photoreceptor cells
- Association of Whirlin with Cav1.3 (α1D) Channels in Photoreceptors, Defining a Novel Member of the Usher Protein Network
- Expression and subcellular localization of USH1C/harmonin in human retina provides insights into pathomechanisms and therapy
- The adhesion G protein-coupled receptor VLGR1/ADGRV1 controls autophagy
- The Adhesion GPCR VLGR1/ADGRV1 Regulates the Ca2+ Homeostasis at Mitochondria-Associated ER Membranes
- Isolation and culturing of primary mouse astrocytes for the analysis of focal adhesion dynamics
- IMMOBILIZATION OF Bacillus subtilis E6-5 PROTEASE AND COMMERCIAL PROTEASE IN NANOFIBRILS CONTAINING DIFFERENT AMINO ACIDS
- Affinity Proteomics Identifies Interaction Partners and Defines Novel Insights into the Function of the Adhesion GPCR VLGR1/ADGRV1
- The adhesion GPCR VLGR1/ADGRV1 regulates focal adhesion turnover by controlling their assembly
- The adhesion G-protein coupled receptor VLGR1/ADGRV1 controls autophagy
- Affinity proteomics identifies novel functional modules related to adhesion GPCRs
- SANS (USH1G) regulates pre-mRNA splicing by mediating the intra-nuclear transfer of tri-snRNP complexes
- Usher syndrome proteins ADGRV1 (USH2C) and CIB2 (USH1J) interact and share a common interactome containing TRiC/CCT-BBS chaperonins
- SANS (USH1G) Molecularly Links the Human Usher Syndrome Protein Network to the Intraflagellar Transport Module by Direct Binding to IFT-B Proteins
- Monitoring paxillin in astrocytes reveals the significance of the adhesion G protein coupled receptor VLGR1/ADGRV1 for focal adhesion assembly
- The expanding functional roles and signaling mechanisms of adhesion G protein-coupled receptors
- Das Usher-Syndrom, eine Ziliopathie des Menschen
- Characterization of the ternary Usher syndrome SANS/ush2a/whirlin protein complex
- Adhesion Class GPCRs in GtoPdb v.2023.1
- A FRAP-Based Method for Monitoring Molecular Transport in Ciliary Photoreceptor Cells In Vivo
- AAV-Mediated Clarin-1 Expression in the Mouse Retina: Implications for USH3A Gene Therapy
- Pgc-1αandNr4a1Are Target Genes of Circadian Melatonin and Dopamine Release in Murine Retina
- An organelle-specific protein landscape identifies novel diseases and molecular mechanisms
- PCARE and WASF3 regulate ciliary F-actin assembly that is required for the initiation of photoreceptor outer segment disk formation
- Enhanced autophagic-lysosomal activity and increased BAG3-mediated selective macroautophagy as adaptive response of neuronal cells to chronic oxidative stress
- Novel Insights Into the Phenotypical Spectrum of KIF11-Associated Retinopathy, Including a New Form of Retinal Ciliopathy
- Deep Sequencing of the Human Retinae Reveals the Expression of Odorant Receptors
- Cilia - The sensory antennae in the eye
- The Abundant Tegument Protein pUL25 of Human Cytomegalovirus Prevents Proteasomal Degradation of pUL26 and Supports Its Suppression of ISGylation
- Identification of Protein Complexes Associated with the Usher Syndrome 2C and Epilepsy-Associated Protein VLGR1 Applying Affinity Proteomics
- Adhesion GPCR-Related Protein Networks
- The Usher syndrome 1C protein harmonin regulates canonical Wnt signaling
- Tackling the Limitations of Copolymeric Small Interfering RNA Delivery Agents by a Combined Experimental-Computational Approach
- Early disruption of photoreceptor cell architecture and loss of vision in a humanized pig model of usher syndromes
- Adhesion G protein-coupled receptor VLGR1/ADGRV1 regulates cell spreading and migration by mechanosensing at focal adhesions
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