Thomas Efferth
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Artemisian-Type Compounds: From Traditional Chinese Medicine to Novel Drugs
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From Molecular Tumor Diagnostics to Individualized Treatment with Phytochemicals Derived from Chinese Herbs
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Animal plant warfare and secondary metabolite evolution
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Diversity of pharmacological properties in Chinese and European medicinal plants: Cytotoxicity, antiviral and antitrypanosomal screening of 82 herbal drugs
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Drug Repurposing in Cancer Therapy
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Prevention of plant crown gall tumor development by the anti-malarial artesunate of Artemisia annua
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Molecular determinants of response of tumor cells to berberine
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Traditional medicine with plants-present and past
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Biotechnology has come of age
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Diagnosis and objective pain assessment of traditional Chinese medicine may be useful to demonstrate specific effects of acupuncture in low back pain: A prospective, randomized, controlled and single blinded pre-study
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Selected secondary plant metabolites for cancer therapy
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Molecular mechanisms and interactions responsible for radio-and chemoresistance of tumors and their modulation by natural products from Ayurveda
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Natural Medicines
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Anti-inflammatory and anti-cancer activity of boswellic acids from frankincense (Boswellia serrata Roxb. et Colebr, B. carterii Birdw.)
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Treatment of Iron-Loaded Veterinary Sarcoma by Artemisia annua
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Adaptogens in chemobrain (Part III): Antitoxic effects of plant extracts towards cancer chemotherapy-induced toxicity - transcriptome-wide microarray analysis of neuroglia cells
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Differentially Tolerized Mouse Antigen Presenting Cells Share a Common miRNA Signature Including Enhanced mmu-miR-223-3p Expression Which Is Sufficient to Imprint a Protolerogenic State
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Molecular bases of the poor response of liver cancer to chemotherapy
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Ziziphora tenuior L. essential oil from Dana Biosphere Reserve (Southern Jordan); Chemical characterization and assessment of biological activities
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Cryptotanshinone deregulates unfolded protein response and eukaryotic initiation factor signaling in acute lymphoblastic leukemia cells
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Induction of cholesterol biosynthesis by archazolid B in T24 bladder cancer cells
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Antiangiogenic Activity and Pharmacogenomics of Medicinal Plants from Traditional Korean Medicine
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First Study of Oral Artenimol-R in Advanced Cervical Cancer: Clinical Benefit, Tolerability and Tumor Markers
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Phytomedicine in Otorhinolaryngology and Pulmonology: Clinical Trials with Herbal Remedies
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Natural Products in Structure-Assisted Design of Molecular Cancer Therapeutics
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Effect of artesunate on immune cells in ret-transgenic mouse melanoma model
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EGFR but not PDGFR-β expression correlates to the antiproliferative effect of growth factor withdrawal in glioblastoma multiforme cell lines
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RECIPROCAL CORRELATION BETWEEN EXPRESSION OF P-GLYCOPROTEIN AND ACCUMULATION OF RHODAMINE-123 IN HUMAN TUMORS
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Small Molecules of Natural Origin for Cancer Therapy and Chemoprevention Part II: Pharmacogenomics and biotechnological applications of small molecules of natural origin for cancer therapy and chemoprevention
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Epidermal Growth Factor Receptors and Downstream Signalling Pathways as Cancer Treatment Targets for Medicinal Plants
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MODULATION OF CORTICOTROPIN RELEASING HORMONE SIGNALING IN MOUSE INTESTINAL ORGANOIDS BY STW 5-II: POSSIBLE MECHANISMS FOR THE MANGAEMNT OF DISORDERS OF GUT-BRAIN INTERACTIONS
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Animals and animal toxins in traditional and modern medicine
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Cytotoxicity of main anthraquinone aglycons towards drug sensitive and multi drug resistant T leukaemia cancer cells
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Cytotoxic activity of mammea type coumarins from Mammea siamensis flowers
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Differential expression of the drug resistance markers DNA topoisomerase IIα and glutathion S-transferase-π in the histological compartments of Wilms' tumors (vol 21, pg 771, 2001)
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Cell growth of sunitinib-resistant renal cell carcinoma was inhibited by Shikonin through necroptosis induction and Akt/mTOR signaling inhibition.
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Cell growth of sunitinib-resistant renal cell carcinoma was inhibited by Shikonin through necroptosis induction and Akt/mTOR signaling inhibition
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Editorial: Phytonutrients in the treatment of cancer: Mechanistic insights and therapeutic prospects
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Jozibrevine D from Ancistrocladus ileboensis, the fifth alkaloid in a series of six possible atropo-diastereomeric naphthylisoquinoline dimers, showing antiparasitic and antileukemic activities
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Pomiferin targets SERCA, mTOR, and P-gp to induce autophagic cell death in apoptosis-resistant cancer cells, and reverses the MDR phenotype in cisplatin-resistant tumors in vivo
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Phytochemical profiling of polyphenols and thyroid stimulatory activity of Ficus religiosa leaf extract in 6-propyl-thiouracil-induced hypothyroid rats
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In Silico and In Vitro Identification of P-Glycoprotein Inhibitors from a Library of 375 Phytochemicals
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The Effect of Plastic-Related Compounds on Transcriptome-Wide Gene Expression on CYP2C19-Overexpressing HepG2 Cells
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A critical review of machine-learning for "multi-omics" marine metabolite datasets
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Cytotoxicity, acute and sub-chronic toxicities of the leaves of Bauhinia thonningii (Schumach.) Milne-Redh. (Caesalpiniaceae)
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Anticancer activity of Bacopa monnieri through apoptosis induction and mitophagy-dependent NLRP3 inflammasome inhibition in oral squamous cell carcinoma
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Anti-inflammatory effects of herbal preparation STW5-II in cytokine challenged normal human colon cells
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Drug repurposing using transcriptome sequencing and virtual drug screening in a patient with glioblastoma
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Shikonin Reduces Growth of Docetaxel-Resistant Prostate Cancer Cells Mainly through Necroptosis
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Antiproliferative Properties of a Few Auranofin-Related Gold (I) and Silver (I) Complexes in Leukemia Cells and their Interferences with the Ubiquitin Proteasome System
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Identification of NF-κB as Determinant of Posttraumatic Stress Disorder and Its Inhibition by the Chinese Herbal Remedy Free and Easy Wanderer
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Elatumic Acid: A New Ursolic Acid Congener from Omphalocarpum elatum Miers (Sapotaceae)
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West meets east: open up a dialogue on phytomedicine
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The triterpenoid ursolic acid ameliorates stress in Caenorhabditis elegans by affecting the depression-associated genes skn-1 and prdx2
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Anti-inflammatory and tight junction protective activity of the herbal preparation STW 5-II on mouse intestinal organoids
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Role of Levo-tetrahydropalmatine and its metabolites for management of chronic pain and opioid use disorders
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In Vitro and In Silico Studies of Two 1,4-Naphthoquinones and their Topi- cal Formulation in Bigels
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Botanicals and phytochemicals from the bark of Hypericum roeperianum (Hypericaceae) had strong antibacterial activity and showed synergistic effects with antibiotics against multidrug-resistant bacteria expressing active efflux pumps
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Cytotoxic alkaloids from the root of Zanthoxylum paracanthum (mildbr) Kokwaro
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Identification of novel drug resistance mechanisms by genomic and transcriptomic profiling of glioblastoma cells with mutation-activated EGFR
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Screening of potent phytochemical inhibitors against SARS-CoV-2 protease and its two Asian mutants
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Chemoprevention and therapeutic role of essential oils and phenolic compounds: Modeling tumor microenvironment in glioblastoma
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Withanone Ameliorates Stress Symptoms in Caenorhabditis Elegans by Acting through Serotonin Receptors
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Increased Stress Resistance and Lifespan in Chaenorhabditis elegans Wildtype and Knockout Mutants-Implications for Depression Treatment by Medicinal Herbs
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Bioactivity of fractions and constituents of Piper capense fruits towards a broad panel of cancer cells
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Toxicity as prime selection criterion among SARS-active herbal medications
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Induction of stress resistance and extension of lifespan in Chaenorhabditis elegans serotonin-receptor knockout strains by withanolide A
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Artesunate Impairs Growth in Cisplatin-Resistant Bladder Cancer Cells by Cell Cycle Arrest, Apoptosis and Autophagy Induction
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Ursolic acid ameliorates stress and reactive oxygen species in C. elegans knockout mutants by the dopamine Dop1 and Dop3 receptors
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Identification of metastasis-related genes by genomic and transcriptomic studies in murine melanoma
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AMG900 as novel inhibitor of the translationally controlled tumor protein
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Genomic landscape analyses in cervical carcinoma and consequences for treatment
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Exploring natural products-based cancer therapeutics derived from egyptian flora
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Induction of Apoptosis, Autophagy and Ferroptosis by Thymus vulgaris and Arctium lappa Extract in Leukemia and Multiple Myeloma Cell Lines
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Cytotoxicity of botanicals and isolated phytochemicals from Araliopsis soyauxii Engl. (Rutaceae) towards a panel of human cancer cells
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Cytotoxicity and apoptosis induction by Fumaria officinalis extracts in leukemia and multiple myeloma cell lines
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Effect of ABC transporter expression and mutational status on survival rates of cancer patients
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Multiple modes of cell death in neuroendocrine tumors induced by artesunate
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Evaluation of Long-Time Decoction-DetoxicatedHei-Shun-Pian(ProcessedAconitum carmichaeliDebeaux Lateral Root With Peel) for Its Acute Toxicity and Therapeutic Effect on Mono-Iodoacetate Induced Osteoarthritis
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Salvia ceratophyllaL. from South of Jordan: new insights on chemical composition and biological activities
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Steroidal saponins from Raphia vinifera and their cytotoxic activity
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Comprehensive Overview on Multiple Strategies Fighting COVID-19
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Cytotoxic bufadienolides from the leaves of a medicinal plant Melianthus comosus collected in South Africa
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Identification of potential inhibitors targeting BRAF-V600E mutant melanoma cells
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Investigation of cancer drug resistance mechanisms by phosphoproteomics
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Putative molecular determinants mediating sensitivity or resistance towards carnosic acid tumor cell responses
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Cytotoxic Bufadienolides from the Leaves of Melianthus major
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Targeting epigenetics in cancer: therapeutic potential of flavonoids
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N-acetylglycoside of oleanolic acid (aridanin) displays promising cytotoxicity towards human and animal cancer cells, inducing apoptotic, ferroptotic and necroptotic cell death
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Immunotoxicity of Therapeutic Antibodies and Nanoparticles
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Organoids of human airways to study infectivity and cytopathy of SARS-CoV-2
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8,8-bis-(Dihydroconiferyl)-diferulate displayed impressive cytotoxicity towards a panel of human and animal cancer cells
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Cryptochlorogenic acid attenuates LPS-induced inflammatory response and oxidative stress via upregulation of the Nrf2/HO-1 signaling pathway in RAW 264.7 macrophages
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Indeno[1,2,3-cd]pyrene and picene mediate actions via estrogen receptor α signaling pathway in in vitro cell systems, altering gene expression
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Anti-inflammatory and anti-cancer activities of frankincense: Targets, treatments and toxicities
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Cardiotoxicity and Cardioprotection by Artesunate in Larval Zebrafish
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Small molecule inhibitors and stimulators of inducible nitric oxide synthase in cancer cells from natural origin (phytochemicals, marine compounds, antibiotics)
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Retrospective study of small pet tumors treated with Artemisia annua and iron
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The antioxidant 2,3-dichloro,5,8-dihydroxy,1,4-naphthoquinone inhibits acetyl-cholinesterase activity and amyloid β42 aggregation: A dual target therapeutic candidate compound for the treatment of Alzheimer's disease
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Terpenoid bio-transformations and applications via cell/organ cultures: a systematic review
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A Machine Learning-Based Prediction Platform for P-Glycoprotein Modulators and Its Validation by Molecular Docking
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Comparison between tumors in plants and human beings: Mechanisms of tumor development and therapy with secondary plant metabolites
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Combining the wisdoms of traditional medicine with cutting-edge science and technology at the forefront of medical sciences
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Interactions between artemisinin derivatives and P-glycoprotein
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Professor Hildebert Wagner celebrates his 90th birthday
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Broad-spectrum Cross-resistance to Anticancer Drugs Mediated by Epidermal Growth Factor Receptor
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Antiulcer activity of Cyperus alternifolius in relation to its UPLC-MS metabolite fingerprint: A mechanistic study
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Editorial: Chemoprevention of cancer by natural products
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Plants mentioned in the Islamic Scriptures (Holy Qur'an and Ahadith): Traditional uses and medicinal importance in contemporary times
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Ca2+ signalling plays a role in celastrol-mediated suppression of synovial fibroblasts of rheumatoid arthritis patients and experimental arthritis in rats
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Development of artemisinin resistance in malaria therapy
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Chondroprotective effects of platelet lysate towards monoiodoacetate-induced arthritis by suppression of TNF-α-induced activation of NF-κB pathway in chondrocytes
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Collateral sensitivity of drug-resistant ABCB5-and mutation-activated EGFR overexpressing cells towards resveratrol due to modulation of SIRT1 expression
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Relationship between EGFR expression and subcellular localization with cancer development and clinical outcome
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Effects of anti-inflammatory and adaptogenic herbal extracts on gene expression of eicosanoids signaling pathways in isolated brain cells
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Adaptogens in chemobrain (Part II): Effect of plant extracts on chemotherapy-induced cytotoxicity in neuroglia cells
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Anti-poliovirus activity of Nerium oleander aqueous extract
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Cytotoxicity of isoflavones and biflavonoids from Ormocarpum kirkii towards multi-factorial drug resistant cancer
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2′-O-galloylhyperin attenuates LPS-induced acute lung injury via upregulation antioxidation and inhibition of inflammatory responses in vivo
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Adaptogens in chemobrain (Part I): Plant extracts attenuate cancer chemotherapy-induced cognitive impairment - Transcriptome-wide microarray profiles of neuroglia cells
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IN VIVO ACUTE TOXICITY OF DETOXIFIED FUZI (LATERAL ROOT OF ACONITUM CARMICHAELI) AFTER A TRADITIONAL DETOXIFICATION PROCESS
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Cardenolides: Insights from chemical structure and pharmacological utility
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Cell Harvesting Methods Affect Cellular Integrity of Adherent Cells During Apoptosis Detection
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Agkistrodon ameliorates pain response and prevents cartilage degradation in monosodium iodoacetate-induced osteoarthritic rats by inhibiting chondrocyte hypertrophy and apoptosis
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Intra-Articular Injection of Fructus Ligustri Lucidi Extract Attenuates Pain Behavior and Cartilage Degeneration in Mono-Iodoacetate Induced Osteoarthritic Rats
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Cytotoxicity of nimbolide towards multidrug-resistant tumor cells and hypersensitivity via cellular metabolic modulation
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Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology
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Curcumin downregulates expression of opioid-related nociceptin receptor gene (OPRL1) in isolated neuroglia cells
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Epimagnolin A, a tetrahydrofurofuranoid lignan from Magnolia fargesii, reverses ABCB1-mediated drug resistance
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Diabetes and Metabolism Disorders Medicinal Plants: A Glance at the Past and a Look to the Future 2018
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Biopiracy of medicinal plants: Finding fair solutions for the use of natural resources
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Correction: Immunogenicity of mammary tumor cells can be induced by shikonin via direct binding-interference with hnRNPA1
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Cytotoxicity of epunctanone and four other phytochemicals isolated from the medicinal plants Garcinia epunctata and Ptycholobium contortum towards multi-factorial drug resistant cancer cells
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Total ginsenosides of Chinese ginseng induces cell cycle arrest and apoptosis in colorectal carcinoma HT-29 cells
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Prospecting for cytotoxic and antiprotozoal 4-aryl-4H-chromenes and 10-aryldihydropyrano[2,3-f]chromenes
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Natural Products as a Source for New Leads in Cancer Research and Treatment
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Cytotoxicity of abietane diterpenoids from Salvia multicaulis towards multidrug-resistant cancer cells
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Selective inhibition of P-gp transporter by goniothalamin derivatives sensitizes resistant cancer cells to chemotherapy
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Identification of fatal outcome in a childhood nasopharyngeal carcinoma patient by protein expression profiling
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2′-O-Galloylhyperin Isolated From Pyrola incarnata Fisch Attenuates LPS-Induced Inflammatory Response by Activation of SIRT1/Nrf2 and Inhibition of the NF-κB Pathways in Vitro and Vivo
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The hydrolysis of 6-phosphogluconolactone in the second step of pentose phosphate pathway occurs via a two-water mechanism
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Synthesis of Novel Hybrids of Quinazoline and Artemisinin with High Activities against Plasmodium falciparum, Human Cytomegalovirus, and Leukemia Cells
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Polyacanthoside A, a new oleanane-type triterpenoid saponin with cytotoxic effects from the leaves of Acacia polyacantha (Fabaceae)
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Antimicrobial and Antioxidant Activities of Natural Compounds
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Prevention of carcinogenesis and metastasis by Artemisinin-type drugs
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Betulinic Acid Exerts Cytotoxic Activity Against Multidrug-Resistant Tumor Cells via Targeting Autocrine Motility Factor Receptor (AMFR)
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Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin
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Oridonin Targets Multiple Drug-Resistant Tumor Cells as Determined by in Silico and in Vitro Analyses
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Total Synthesis and Biological Investigation of (-)-Artemisinin: The Antimalarial Activity of Artemisinin Is not Stereospecific
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Cytotoxic flavonoids from two Lonchocarpus species
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Insights into apoptotic proteins in chemotherapy: quantification techniques and informing therapy choice
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Aloe-emodin as drug candidate for cancer therapy
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Threats to human health by great ocean garbage patches
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Treatment of Multidrug-Resistant Leukemia Cells by Novel Artemisinin-, Egonol-, and Thymoquinone-Derived Hybrid Compounds
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In Vitro Antioxidant and Cytotoxic Activities of 18 Plants from the Erkowit Region, Eastern Sudan
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Multifactorial Modes of Action of Arsenic Trioxide in Cancer Cells as Analyzed by Classical and Network Pharmacology
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Daphne striata Tratt. and D. mezereum L.: a study of anti-proliferative activity towards human cancer cells and antioxidant properties
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Cytotoxic activity of medicinal plants of the Kakamega County (Kenya) against drug-sensitive and multidrug-resistant cancer cells
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Role of TCTP for Cellular Differentiation and Cancer Therapy
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Cancer combination therapy of the sesquiterpenoid artesunate and the selective EGFR-tyrosine kinase inhibitor erlotinib
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Introduction: Novel hybrid combinations containing synthetic or antibiotic drugs with plant-derived phenolic or terpenoid compounds
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Lawsone derivatives target the Wnt/β-catenin signaling pathway in multidrug-resistant acute lymphoblastic leukemia cells
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Artemisinin Derivatives Target Topoisomerase 1 and Cause DNA Damage in Silico and in Vitro
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North African Medicinal Plants Traditionally Used in Cancer Therapy
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Cytotoxicity and mode of action of a naturally occurring naphthoquinone, 2-acetyl-7-methoxynaphtho[2,3-b]furan-4,9-quinone towards multi-factorial drug-resistant cancer cells
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Antileukemic ancistrobenomine B and related 5,1'-coupled naphthylisoquinoline alkaloids from the Chinese liana Ancistrocladus tectorius
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Synthesis and cytotoxic activity of new artemisinin hybrid molecules against human leukemia cells
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Mode of Action Analyses of Neferine, a Bisbenzylisoquinoline Alkaloid of Lotus (Nelumbo nucifera) against Multidrug-Resistant Tumor Cells
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Answer to the comment of Hai Lu et al. regarding "Hepatotoxicity by combination treatment of temozolomide, artesunate and Chinese herbs in a glioblastoma multiforme patient: case report and review of the literature. Arch Toxicol (2016)"
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Drug Repurposing of the Anthelmintic Niclosamide to Treat Multidrug-Resistant Leukemia
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The road in front of us: Phytomedical research for the years to come
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Both Phenolic and Non-phenolic Green Tea Fractions Inhibit Migration of Cancer Cells
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Total coumarins of Hedyotis diffusa induces apoptosis of myelodysplastic syndrome SKM-1 cells by activation of caspases and inhibition of PI3K/Akt pathway proteins
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Anti-Proliferative and Apoptosis-Inducing Effect of Theabrownin against Non-small Cell Lung Adenocarcinoma A549 Cells
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Genomic and transcriptomic profiling of resistant CEM/ADR-5000 and sensitive CCRF-CEM leukaemia cells for unravelling the full complexity of multi- factorial multidrug resistance
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Anti-inflammatory Effects of Herbal Preparations STW5 and STW5-II in Cytokine-Challenged Normal Human Colon Cells
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Systematic Review on Post-Traumatic Stress Disorder Among Survivors of the Wenchuan Earthquake
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Ancistectorine D, a naphthylisoquinoline alkaloid with antiprotozoal and antileukemic activities, and further 5,8′- and 7,1′-linked metabolites from the Chinese liana Ancistrocladus tectorius
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Substrate Specificity of Aglaia loheri Active Isolate towards P-glycoprotein in Multidrug-Resistant Cancer Cells
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Fatal Liver and Bone Marrow Toxicity by Combination Treatment of Dichloroacetate and Artesunate in a Glioblastoma Multiforme Patient: Case Report and Review of the Literature
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Antibacterial activities and structure-activity relationships of a panel of 48 compounds from Kenyan plants against multidrug resistant phenotypes
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Tumor Heterogeneity, Single-Cell Sequencing, and Drug Resistance
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Modulation of P-glycoprotein activity by novel synthetic curcumin derivatives in sensitive and multidrug-resistant T-cell acute lymphoblastic leukemia cell lines
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Cytotoxicity of 15 Cameroonian medicinal plants against drug sensitive and multi-drug resistant cancer cells
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Pharmacogenomics of Scopoletin in Tumor Cells
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Peptide aptamer identified by molecular docking targeting translationally controlled tumor protein in leukemia cells
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Hildebert Wagner Award Laureate announcement December 2015
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In Vivo Cardiotoxicity Induced by Sodium Aescinate in Zebrafish Larvae
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Cytotoxicity of an unprecedented brominated oleanolide and a new furoceramide from the Cameroonian spice, Echinops giganteus
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Interactions of human P-glycoprotein transport substrates and inhibitors at the drug binding domain: Functional and molecular docking analyses
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Production of rosmarinic acid and salvianolic acid B from callus culture of Salvia miltiorrhiza with cytotoxicity towards acute lymphoblastic leukemia cells
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Cytotoxicity of 91 Kenyan indigenous medicinal plants towards human CCRF-CEM leukemia cells
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A Five-year Survey of Cancer Prevalence in Sudan
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Activity of Artemisia annua and artemisinin derivatives, in prostate carcinoma
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Hormesis: Decoding Two Sides of the Same Coin
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Anticancer activity of cryptotanshinone on acute lymphoblastic leukemia cells
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Molecular Docking Analysis of Steroid-based Copper Transporter 1 Inhibitors
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The broad-spectrum antiinfective drug artesunate interferes with the canonical nuclear factor kappa B (NF-κB) pathway by targeting RelA/p65
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Activity of the antiestrogenic cajanin stilbene acid towards breast cancer
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Human ABCB1 confers cells resistance to cytotoxic guanidine alkaloids from Pterogyne nitens
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Cytotoxicity of a naturally occurring furoquinoline alkaloid and four acridone alkaloids towards multi-factorial drug-resistant cancer cells
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Cytotoxicity of 35 medicinal plants from Sudan towards sensitive and multidrug-resistant cancer cells
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Highly potent artemisinin-derived dimers and trimers: Synthesis and evaluation of their antimalarial, antileukemia and antiviral activities
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Cytotoxicity of anthraquinones from the roots of Pentas schimperi towards multi-factorial drug-resistant cancer cells
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New efficient artemisinin derived agents against human leukemia cells, human cytomegalovirus and Plasmodium falciparum: 2nd generation 1,2,4-trioxane-ferrocene hybrids
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Novel sequential stress model for functional dyspepsia: Efficacy of the herbal preparation STW5
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Bacteria-Derived Compatible Solutes Ectoine and 5α-Hydroxyectoine Act as Intestinal Barrier Stabilizers to Ameliorate Experimental Inflammatory Bowel Disease
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Miltirone Induces G2/M Cell Cycle Arrest and Apoptosis in CCRF-CEM Acute Lymphoblastic Leukemia Cells
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Cell cycle arrest and induction of apoptosis by cajanin stilbene acid from Cajanus cajun in breast cancer cells
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Kaempferol Is an Anti-Inflammatory Compound with Activity towards NF-xB Pathway Proteins
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Cytotoxicity of medicinal plants of the West-Canadian Gwich'in Native Americans towards sensitive and multidrug-resistant cancer cells
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Quantitative Structure-Activity Relationship and Molecular Docking of Artemisinin Derivatives to Vascular Endothelial Growth Factor Receptor 1
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Substituted Steroidal Compounds Containing Amino and Amido Groups Reverse Multidrug Resistance of Mouse T-Lymphoma and Two Human Prostate Cancer Cell Lines In Vitro
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Cytotoxicity of natural products and derivatives toward MCF-7 cell monolayers and cancer stem-like mammospheres
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Cytotoxicity of the indole alkaloid reserpine from Rauwoffia serpentina against drug-resistant tumor cells
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Cytotoxicity of cardiotonic steroids in sensitive and multidrug-resistant leukemia cells and the link with Na+/K+-ATPase
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Laurus nobilis L. Seed Extract Reveals Collateral Sensitivity in Multidrug-Resistant P-Glycoprotein-Expressing Tumor Cells
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Aptamers as a novel tool for diagnostics and therapy
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Shikonin and its derivatives inhibit the epidermal growth factor receptor signaling and synergistically kill glioblastoma cells in combination with erlotinib
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Pharmacogenomic Characterization of Cytotoxic Compounds from Salvia officinalis in Cancer Cells
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Synthetic cajanin stilbene acid derivatives inhibit c-MYC in breast cancer cells
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Dis-organizing Centrosomal Clusters: Specific Cancer Therapy for a Generic Spread?
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Phytochemical profile and bioactivity of traditional ayurvedic decoctions and hydro-alcoholic macerations of Boerhaavia diffusa L. and Curculigo orchioides Gaertn.
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Pharmacogenomic and molecular docking studies on the cytotoxicity of the natural steroid wortmannin against multidrug-resistant tumor cells
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Activity of the dietary flavonoid, apigenin, against multidrug-resistant tumor cells as determined by pharmacogenomics and molecular docking
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Efficient Production of Isoflavonoids by Astragalus membranaceus Hairy Root Cultures and Evaluation of Antioxidant Activities of Extracts
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Posttraumatic stress disorder among earthquake survivors of the Wenchuan area (Sichuan, China)
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Pharmacogenetic Prediction of Individual Variability in Drug Response Based on CYP2D6, CYP2C9 and CYP2C19 Genetic Polymorphisms
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Cytotoxicity of the bisphenolic honokiol from Magnolia officinalis against multiple drug-resistant tumor cells as determined by pharmacogenomics and molecular docking
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Identification of new P-glycoprotein inhibitors derived from cardiotonic steroids
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Cytotoxic Benzophenanthridine and Furoquinoline Alkaloids from Zanthoxylum buesgenii (Rutaceae)
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Synthesis and Anti-Tumor Activity of Novel Aminomethylated Derivatives of Isoliquiritigenin
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Targeting epidermal growth factor receptors and downstream signaling pathways in cancer by phytochemicals
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Acupuncture and Herbal Medicine for Cancer Patients 2014
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Unprecedented new nonadecyl para-hydroperoxycinnamate isolated from Erythrina excelsa and its cytotoxic activity
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Negative pressure cavitation-microwave assisted preparation of extract of Pyrola incarnata Fisch. rich in hyperin, 2′-O-galloylhyperin and chimaphilin and evaluation of its antioxidant activity
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Resistance mechanisms of cancer cells to the novel vacuolar H+-ATPase inhibitor archazolid B
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Effects of Acupuncture on Leucopenia, Neutropenia, NK, and B Cells in Cancer Patients: A Randomized Pilot Study
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Up-regulation of cholesterol associated genes as novel resistance mechanism in glioblastoma cells in response to archazolid B
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Cytotoxicity and inhibition of P-glycoprotein by selected medicinal plants from Thailand
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The ability of molecular docking to unravel the controversy and challenges related to P-glycoprotein-a well-known, yet poorly understood drug transporter
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The eucalyptus oil ingredient 1,8-cineol induces oxidative DNA damage
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Cytotoxicity and modes of action of five Cameroonian medicinal plants against multi-factorial drug resistance of tumor cells
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Contributions from emerging transcriptomics technologies and computational strategies for drug discovery
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Tumor-specific blood serum factors as determinants of tumor growth.
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Cytotoxicity of Novel Sulfanilamides Towards Sensitive and Multidrug-resistant Leukemia Cells
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The lignan, (-)-sesamin reveals cytotoxicity toward cancer cells: Pharmacogenomic determination of genes associated with sensitivity or resistance
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Synthesis and study of cytotoxic activity of 1,2,4-trioxane- and egonol-derived hybrid molecules against Plasmodium falciparum and multidrug-resistant human leukemia cells
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Acupuncture and Herbal Medicine for Cancer Patients
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Pharmacogenomics of cantharidin in tumor cells
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Nitensidine A, a guanidine alkaloid from Pterogyne nitens, is a novel substrate for human ABC transporter ABCB1
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A phenolic ester from Aglaia loheri leaves reveals cytotoxicity towards sensitive and multidrug-resistant cancer cells
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Can Medical Herbs Stimulate Regeneration or Neuroprotection and Treat Neuropathic Pain in Chemotherapy-Induced Peripheral Neuropathy?
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Variation in Contents of Main Active Components and Antioxidant Activity in Leaves of Different Pigeon Pea Cultivars during Growth
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Cytotoxicity of Elaoephorbia drupifera and other Cameroonian medicinal plants against drug sensitive and multidrug resistant cancer cells
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Cytotoxicity and Pharmacogenomics of Medicinal Plants from Traditional Korean Medicine
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Integration of Different "-omics" Technologies Identifies Inhibition of the IGF1R-Akt-mTOR Signaling Cascade Involved in the Cytotoxic Effect of Shikonin against Leukemia Cells
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Antiproliferative and Erythroid Differentiation of Piperazine and Triphenyl Derivatives Against K-562 Human Chronic Myelogenous Leukemia
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Novel artemisinin derivatives with potential usefulness against liver/colon cancer and viral hepatitis
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Cytotoxicity and modes of action of four Cameroonian dietary spices ethno-medically used to treat Cancers: Echinops giganteus, Xylopia aethiopica, Imperata cylindrica and Piper capense
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Safety and Efficacy Field Study of Artesunate for Dogs with Non-resectable Tumours
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Microwave-Assisted Synthesis of New Selenazole Derivatives with Antiproliferative Activity
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Glycyrrhizic acid nanoparticles inhibit LPS-induced inflammatory mediators in 264.7 mouse macrophages compared with unprocessed glycyrrhizic acid
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Cajaninstilbene acid (CSA) exerts cytoprotective effects against oxidative stress through the Nrf2-dependent antioxidant pathway
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Objectifying Acupuncture Effects by Lung Function and Numeric Rating Scale in Patients Undergoing Heart Surgery
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Dihydroquercetin (DHQ) Induced HO-1 and NQO1 Expression against Oxidative Stress through the Nrf2-Dependent Antioxidant Pathway
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Polo-like kinase 1 as target for cancer therapy
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UV-Induced Changes of Active Components and Antioxidant Activity in Postharvest Pigeon Pea [Cajanus cajan (L.) Millsp.] Leaves
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Alkamides from Echinacea angustifolia Interact with P-Glycoprotein of Primary Brain Capillary Endothelial Cells Isolated from Porcine Brain Blood Vessels
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Identification by High-throughput In Silico Screening of Radio-protecting Compounds Targeting the DNA-binding Domain of the Tumor Suppressor p53
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Qigong therapy for physiotherapists suffering from burnout: a preliminary study
-
Mode of Cell Death Induction by Pharmacological Vacuolar H+-ATPase (V-ATPase) Inhibition
-
Aspidin PB, a phloroglucinol derivative, induces apoptosis in human hepatocarcinoma HepG2 cells by modulating PI3K/Akt/GSK3β pathway
-
Molecular interaction of artemisinin with translationally controlled tumor protein (TCTP) of Plasmodium falciparum
-
Inhibition in vivo of the activity of botulinum neurotoxin A by small molecules selected by virtual screening
-
Growth-dependent release of carbohydrate metabolism-related and antioxidant enzymes from Staphylococcus aureus strain 6 as determined by proteomic analysis
-
Effects of qigong on performance-related anxiety and physiological stress functions in transverse flute music schoolchildren: a feasibility study
-
New artesunic acid homodimers: Potent reversal agents of multidrug resistance in leukemia cells
-
Microarray-based mRNA Expression Profiling of Leukemia Cells Treated with the Flavonoid, Casticin
-
Polyhydroxylated Steroidal Glycosides from Paris polyphylla
-
Anti-Infective and Antiproliferative Potential of African Medicinal Plants
-
Can heat and cold be parameterized? Clinical data of a preliminary study
-
Factors Determining Sensitivity and Resistance of Tumor Cells to Arsenic Trioxide
-
In Vitro Antioxidant and Antimicrobial Activity of Extracts from Morus alba L. Leaves, Stems and Fruits
-
The European directive on traditional herbal medicinal products: friend or foe for plant-based therapies?
-
Utilizing inherent fluorescence of therapeutics to analyze real-time uptake and multi-parametric effector kinetics
-
Effects of Scrophularia ningpoensis Hemsl. on Inhibition of Proliferation, Apoptosis Induction and NF-κB Signaling of Immortalized and Cancer Cell Lines
-
In Silico Analysis of Microarray-Based Gene Expression Profiles Predicts Tumor Cell Response to Withanolides
-
Artesunate Induces Oxidative DNA Damage, Sustained DNA Double-Strand Breaks, and the ATM/ATR Damage Response in Cancer Cells
-
Targeting the mitochondrial pathway to induce apoptosis/necrosis through ROS by a newly developed Schiff's base to overcome MDR in cancer
-
Antibacterial Activity and Cytotoxicity of Selected Egyptian Medicinal Plants
-
Anticancer activity of Salvia officinalis essential oil against HNSCC cell line (UMSCC1)
-
Cytotoxic activity of secondary metabolites derived from Artemisia annua L. towards cancer cells in comparison to its designated active constituent artemisinin
-
Pharmacogenomic determination of genes associated with sensitivity or resistance of tumor cells to curcumin and curcumin derivatives
-
Establishment and comparative characterization of novel squamous cell non-small cell lung cancer cell lines and their corresponding tumor tissue
-
Pharmacogenomics of Cameroonian traditional herbal medicine for cancer therapy
-
Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1
-
Inhibition of Tumor Angiogenesis by Antibodies, Synthetic Small Molecules and Natural Products
-
Catalytic Synthesis of α-Oxoketene S,S-Acetals in a Wet Ionic Liquid [Bmim]Cl/H2O Homogeneous System
-
Efficient Lewis Acid Ionic Liquid-Catalyzed Synthesis of the Key Intermediate of Coenzyme Q10 under Microwave Irradiation
-
Chemistry and Pharmacology of Neglected Helminthic Diseases
-
Molecular docking and pharmacogenomics of Vinca alkaloids and their monomeric precursors, vindoline and catharanthine
-
Vaccination and Antiviral Treatment of Neglected Diseases Caused by Flaviviral Infections
-
Toxicogenomics for the Prediction of Toxicity Related to Herbs from Traditional Chinese Medicine
-
Transcript profiling identifies novel key players mediating the growth inhibitory effect of NS-398 on human pancreatic cancer cells
-
Natural Products Derived from Traditional Chinese Medicine as Novel Inhibitors of the Epidermal Growth Factor Receptor
-
MicroRNA expression profile of MCF-7 human breast cancer cells and the effect of green tea polyphenon-60.
-
Therapeutic and Diagnostic Applications of Nanoparticles
-
EVALUATION OF DRUG TRANSPORTERS' SIGNIFICANCE FOR MULTIDRUG RESISTANCE IN HEAD AND NECK SQUAMOUS CELL CARCINOMA
-
Activity investigation of pinostrobin towards herpes simplex virus-1 as determined by atomic force microscopy
-
Fighting mycobacterial infections by antibiotics, phytochemicals and vaccines
-
Cancer Therapy with Natural Products and Medicinal Plants
-
Sensitivity and resistance towards isoliquiritigenin, doxorubicin and methotrexate in T cell acute lymphoblastic leukaemia cell lines by pharmacogenomics
-
Identification of serpin (alpha-1-antitrypsin) as serum growth inhibitory factor in murine ehrlich carcinoma by proteomics.
-
Design of novel artemisinin-like derivatives with cytotoxic and anti-angiogenic properties
-
Inhibition of P-glycoprotein at the blood-brain barrier by phytochemicals derived from traditional Chinese medicine.
-
Personalized Cancer Medicine: From Molecular Diagnostics to Targeted Therapy with Natural Products
-
Cytotoxicity of Artesunic Acid Homo- and Heterodimer Molecules toward Sensitive and Multidrug-Resistant CCRF-CEM Leukemia Cells
-
Enhanced extraction of astragalosides from Radix Astragali by negative pressure cavitation-accelerated enzyme pretreatment
-
Strategies for Overcoming Chemotherapy Resistance in Enterohepatic Tumours
-
Fighting Cancer with Red Wine? Molecular Mechanisms of Resveratrol
-
Berberine Inhibits Cell Growth and Mediates Caspase-Independent Cell Death in Human Pancreatic Cancer Cells
-
A petrol ether extract of the roots of Onosma paniculatum induces cell death in a caspase dependent manner
-
First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases
-
Pharmacogenomic Identification of c-Myc/Max-Regulated Genes Associated with Cytotoxicity of Artesunate towards Human Colon, Ovarian and Lung Cancer Cell Lines
-
Antioxidant Activities and Xanthine Oxidase Inhibitory Effects of Extracts and Main Polyphenolic Compounds Obtained from Geranium sibiricum L.
-
Inhibition of epidermal growth factor receptor-overexpressing cancer cells by camptothecin, 20-(N,N-diethyl) glycinate
-
Factors determining sensitivity or resistance of tumor cell lines towards artesunate
-
Traditional Chinese Medicines (TCMs) for Molecular Targeted Therapies of Tumours
-
Toxicity of the antimalarial artemisinin and its dervatives
-
Inhibition of inducible nitric oxide synthase by bis(helenalinyl)glutarate in RAW264.7 macrophages
-
Plasma pharmacokinetics and tissue distribution study of cajaninstilbene acid in rats by liquid chromatography with tandem mass spectrometry
-
Cytotoxic Activity of Curcumin towards CCRF-CEM Leukemia Cells and Its Effect on DNA Damage
-
Ethnobotanical survey and cytotoxicity testing of plants of South-western Nigeria used to treat cancer, with isolation of cytotoxic constituents from Cajanus cajan Millsp leaves
-
Neglected Diseases Caused By Bacterial Infections
-
Inhibition of epidermal growth factor receptor over-expressing cancer cells by the aphorphine-type isoquinoline alkaloid, dicentrine
-
Rapid microwave-assisted transesterification of yellow horn oil to biodiesel using a heteropolyacid solid catalyst
-
Determination of paclitaxel and its analogues in the needles of Taxus species by using negative pressure cavitation extraction followed by HPLC-MS-MS
-
Microarray analysis of gene expression in medicinal plant research.
-
Chemical composition and biological activity of the essential oil obtained from Bupleurum marginatum (Apiaceae)
-
Natural products pave their way in cancer therapy
-
Detection and Characterization of a Glutathione Conjugate of a Novel Copper Complex
-
Induction of resistance to murine tumor development is associated with alterations in the glycosylation of blood serum proteins
-
Broken dreams or time to test? Chemoselective treatment of MTAP-deficient tumors with L-alanosine
-
Negative-pressure cavitation extraction for the determination of flavonoids in pigeon pea leaves by liquid chromatography-tandem mass spectrometry
-
Drug Resistance of Human Immunodeficiency Virus and Overcoming it by Natural Products
-
Gene expression profiling identifies novel key players involved in the cytotoxic effect of Artesunate on pancreatic cancer cells
-
The Role of Downstream Signaling Pathways of the Epidermal Growth Factor Receptor for Artesunate's Activity in Cancer Cells
-
Lipid rafts play an important role in the vesicular stomatitis virus life cycle
-
Cytotoxic Activity of Isoliquiritigenin towards CCRF-CEM Leukemia Cells and its Effect on DNA Damage
-
The Antibacterial Activity of Clove Essential Oil Against Propionibacterium acnes and Its Mechanism of Action
-
Determination and quantification of astragalosides in Radix Astragali and its medicinal products using LC-MS
-
Drug Resistance in Plasmodium: Natural Products in the Fight Against Malaria
-
Natural products as promising drug candidates for the treatment of hepatitis B and C
-
Molecular Mechanisms of and Clinical Evidence for Interactions Between Natural Products and Drugs
-
Molecular Mechanisms Underlying St. John's Wort Drug Interactions
-
Human cytomegalovirus: Drug resistance and new treatment options using natural products
-
Herpes simplex virus: Drug resistance and new treatment options using natural products (Review)
-
Artesunate derived from traditional Chinese medicine induces DNA damage and repair
-
Activation of the mitochondria-driven pathway of apoptosis in human PC-3 prostate cancer cells by a novel hydrophilic paclitaxel derivative, 7-xylosyl-10-deacetylpaclitaxel
-
Role of transporter genes in cisplatin resistance
-
Microarray-based expression of DNA repair genes does not correlate with growth inhibition of cancer cells by natural products derived from traditional Chinese medicine.
-
Hemoglobin-associated proteins isolated from blood serum of Ehrlich carcinoma-bearing mice
-
Cytotoxicity and p-glycoprotein modulating effects of quinolones and indoloquinazolines from the Chinese herb Evodia rutaecarpa
-
Determination of vitexin and isovitexin in pigeonpea using ultrasonic extraction followed by LC-MS
-
Phytochemistry and pharmacogenomics of natural products derived from traditional Chinese medicine and Chinese materia medica with activity against tumor cells
-
Anti-cancer natural product library from traditional Chinese medicine
-
In vitro cytotoxicity and P-glycoprotein modulating effects of geranylated Furocoumarins from Tetradium daniellii
-
Separation of 7-xylosyl-10-deacetyl paclitaxel and 10-deacetylbaccatin III from the remainder extracts free of paclitaxel using macroporous resins
-
Role of Transferrin Receptor and the ABC Transporters ABCB6 and ABCB7 for Resistance and Differentiation of Tumor Cells towards Artesunate
-
Pharmacogenomics of a traditional Japanese herbal medicine (Kampo) for cancer therapy.
-
Molecular target-guided tumor therapy with natural products derived from traditional Chinese medicine
-
Three-Dimensional Modeling of Glucose-6-phosphate Dehydrogenase-Deficient Variants from German Ancestry
-
Effect of cantharidin, cephalotaxine and homoharringtonine on "in vitro" models of hepatitis B virus (HBV) and bovine viral diarrhoea virus (BVDV) replication
-
Chemotherapy-induced resistance by ATP-binding cassette transporter genes
-
Modulation of human BCRP (ABCG2) activity by anti-HIV drugs
-
Diagnosis and therapy of oral squamous cell carcinoma
-
Willmar Schwabe Award 2006: Antiplasmodial and antitumor activity of arternisinin - From bench to bedside
-
Cytotoxic and new tetralone derivatives from Berchemia floribunda (WALL.) BRONGN.
-
New glycosides from Tetracentron sinense and their cytotoxic activity
-
A novel copper complex induces ROS generation in doxorubicin resistant Ehrlich ascitis carcinoma cells and increases activity of antioxidant enzymes in vital organs in vivo
-
Optimization of luteolin separation from pigeonpea [Cajanus cajan (L.) Millsp.] leaves by macroporous resins
-
ABCA3 as a possible cause of drug resistance in childhood acute myeloid leukemia
-
Activity-guided isolation of scopoletin and isoscopoletin, the inhibitory active principles towards CCRF-CEM leukaemia cells and multi-drug resistant CEM/ADR5000 cells, from Artemisia argyi
-
Antiviral effect of artemisinin from Artemisia annua against a model member of the Flaviviridae family, the bovine viral diarrhoea virus (BVDV)
-
Expression profiling of ATP-binding cassette transporters in childhood T-cell acute lymphoblastic leukemia
-
Overcoming drug-resistant cancer by a newly developed copper chelate through host-protective cytokine-mediated apoptosis
-
Part 1: Pharmacognosy and molecular pharmacology of small molecules of natural origin for cancer therapy and chemoprevention
-
Molecular pharmacology and pharmacogenomics of artemisinin and its derivatives in cancer cells
-
Reversal of drug resistance in P-glycoprotein-expressing T-cell acute lymphoblastic CEM leukemia cells by copper N-(2-hydroxy acetophenone) glycinate and oxalyl bis (N-phenyl) hydroxamic acid
-
Microarray expression profiles of angiogenesis-related genes predict tumor cell response to artemisinins
-
Microarray Expression Profiling of ABC Transporters in Human Breast Cancer.
-
Artesunate in the treatment of metastatic uveal melanoma - first experiences
-
Role of glucose-6-phosphate dehydrogenase for oxidative stress and apoptosis
-
The anti-malaria drug artesunate inhibits replication of cytomegalovirus in vitro and in vivo
-
Relationship between molecular variants and clinical manifestions in twelve glucose-6-phosphate dehydrogenase-deficient patients in Jordan
-
Effect of artemisinin/artesunate as inhibitors of hepatitis B virus production in an "in vitro" replicative system
-
Molecular modeling of O6-methylguanine-DNA methyltransferase mutant proteins encoded by single nucleotide polymorphisms
-
Glutathione-related enzymes contribute to resistance of tumor cells and low toxicity in normal organs to artesunate
-
Pharmacogenetics for individualized cancer chemotherapy
-
FISH studies on the telomeric regions of the T-cell acute lymphoblastic leukemia cell line CCRF-CEM
-
Molecular modes of action of cantharidin in tumor cells
-
Indole and carbazole alkaloids from Glycosmis montana with weak anti-HIV and cytotoxic activities
-
Genomic gain of the epidermal growth factor receptor harboring band 7p12 is part of a complex pattern of genomic imbalances in oral squamous cell carcinomas
-
Microarray-based prediction of cytotoxicity of tumor cells to cantharidin
-
Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron
-
Glucose-6-phosphate dehydrogenase (G6PD) deficiency-type Zurich: a splice site mutation as an uncommon mechanism producing enzyme deficiency
-
Homozygous deletions of CDKN2A caused by alternative mechanisms in various human cancer cell lines
-
Activity of novel plant extracts against medullary thyroid carcinoma cells
-
Oxidative stress response of tumor cells: microarray-based comparison between artemisinins and anthracyclines
-
Microarray-based Prediction of Cytotoxicity of Tumor Cells to Arsenic Trioxide.
-
Inverse correlation of epidermal growth factor receptor messenger RNA induction and suppression of anchorage-independent growth by OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in glioblastoma multiforme cell lines
-
Combination-treatment of glioblastoma multiforme cell lines with the anti-malarial artesunate and the epidermal growth factor receptor tyrosine kinase inhibitor OSI-774
-
Lung Cancer Protein Expression Profiles of Smokers and Non-Smokers.
-
Identification of gene expression profiles predicting tumor cell response to L-alanosine
-
Protein Expression Profiles Indicative for Drug Resistance of Kidney Carcinoma.
-
Analysis of single nucleotide polymorphism C3435T of the multidrug resistance gene MDR1 in acute lymphoblastic leukemia
-
MDR1 single nucleotide polymorphism C3435T in normal colorectal tissue and colorectal carcinomas detected by MALDI-TOF mass spectrometry
-
Molecular modes of action of cephalotaxine and homoharringtonine from the coniferous tree Cephalotaxus hainanensis in human tumor cell lines
-
Comparative M-FISH and CGH analyses in sensitive and drug-resistant human T-cell acute leukemia cell lines
-
Specific patterns of DNA copy number gains and losses in eight new glioblastoma multiforme cell lines
-
Synergism between rViscumin and cisplatin is not dependent on ERCC-1 expression
-
Adenosine triphosphate-binding cassette transporter genes in ageing and age-related diseases
-
Genomic imbalances in drug-resistant T-cell acute lymphoblastic CEM leukemia cell lines
-
Activity of ascaridol from the anthelmintic herb Chenopodium anthelminticum L. against sensitive and multidrug resistant tumor cells
-
Protein expression profiles indicative for drug resistance of non-small cell lung cancer
-
Protein expression profile of primary human squamous cell lung carcinomas indicative of the incidence of metastases
-
Genomic imbalances in T-cell acute lymphoblastic leukemia cell lines
-
mRNA expression profiles for the response of human tumor cell lines to the antimalarial drugs artesunate, arteether, and artemether
-
Protein expression profile of newly diagnosed acute lymphoblastic leukemia in children developing relapses
-
Protein expression profiles of non-small cell lung carcinomas:: Correlation with histological subtype
-
Activity of Drugs from Traditional Chinese Medicine toward Sensitive and MDR1- or MRP1-Overexpressing Multidrug-Resistant Human CCRF-CEM Leukemia Cells
-
Use of CpG island microarrays to identify colorectal tumors with a high degree of concurrent methylation
-
Antiviral activity of artesunate towards wild-type, recombinant, and ganciclovir-resistant human cytomegaloviruses
-
Methylthioadenosine phosphorylase as target for chemoselective treatment of T-cell acute lymphoblastic leukemic cells
-
Interleukin-6 affects melphalan-induced DNA damage and repair in human multiple myeloma cells
-
Expression profile of genes in non-small cell lung carcinomas from long-term surviving patients
-
Expression profile of proteins involved in the xenotransplantability of non-small cell lung cancers into athymic nude mice
-
The Human ATP-Binding Cassette Transporter Genes From the Bench to the Bedside
-
[Hope for gene therapy. Is this the future of tumor treatment?].
-
5-azacytidine modulates the response of sensitive and multidrug-resistant K562 leukemic cells to cytostatic drugs
-
Prognostic impacts of cytogenetic findings in clear cell renal cell carcinoma:: Gain of 5q31-qter predicts a distinct clinical phenotype with favorable prognosis
-
Differential expression of the heat shock protein 70 in the histological compartments of nephroblastomas
-
Differential expression of the drug resistance markers DNA topoisomerase IIα and glutathione S-transferase-π in the histological compartments of Wilms' tumors
-
Differential expression of the lung resistance-related protein/major vault protein in the histological compartments of nephroblastomas
-
Differential expression of the multidrug resistance-related protein MRP1 in the histological compartments of nephroblastomas
-
The anti-malarial artesunate is also active against cancer
-
DNA damage and apoptosis in mononuclear cells from glucose-6-phosphate dehydrogenase-deficient patients (G6PD Aachen variant) after UV irradiation
-
Damage of the kinesin heavy chain gene contributes to the antagonism of cisplatin and paclitaxel
-
Biomedical technology in Franconia
-
Molecular characterization of a German variant of glucose-6-phosphate dehydrogenase deficiency (G6PD Aachen)
-
Leptin contributes to the protection of human leukemic cells from cisplatinum cytotoxicity
-
Impact of viral oncogenesis on responses to anti-cancer drugs and irradiation
-
Testing for tumor drug resistance in the age of molecular medicine. A contribution to the Debate Round-Table on phenotypic and genotypic analyses of multidrug resistance (MDR) in clinical hospital practice
-
Apoptosis and resistance to daunorubicin in human leukemic cells
-
SISTER-CHROMATID EXCHANGE INDUCING DNA LESIONS AND DEPRESSION OF ACTIVATION MARKERS ON THE SURFACE OF CULTURED PERIPHERAL-BLOOD MONONUCLEAR-CELLS AFTER THE ADDITION OF STREPTOCOCCAL PYROGENIC EXOTOXIN-A AND EXOTOXINC
-
Detection of apoptosis in KG-1a leukemic cells treated with investigational drugs
-
Anti-Fas/Apo-1 monoclonal antibody CH-11 depletes glutathione and kills multidrug-resistant human leukemic cells
-
INDUCTION OF P-GLYCOPROTEIN, GLUTATHIONE-S-TRANSFERASE-PI, CATALASE, C-FOS AND C-ERBB1 IN RODENT CELL-LINES AFTER EXPOSURE TO DOXORUBICIN, ETHANOL AND CAFFEINE
-
EXPRESSION OF APOPTOSIS-RELATED ONCOPROTEINS AND MODULATION OF APOPTOSIS BY CAFFEINE IN HUMAN LEUKEMIC-CELLS
-
INCREASED INDUCTION OF APOPTOSIS IN MONONUCLEAR-CELLS OF A GLUCOSE-6-PHOSPHATE-DEHYDROGENASE DEFICIENT PATIENT
-
OVERCOMING DRUG-RESISTANCE OF TUMORS
-
INTRINSIC OVEREXPRESSION OF 2 DIFFERENT MECHANISMS OF RESISTANCE TO CHEMOTHERAPY (P-GLYCOPROTEIN AND GST-PI) IN HUMAN ENDOMETRIAL CARCINOMA
-
INCREASE OF ALKALINE-PHOSPHATASE IN MULTIDRUG-RESISTANT TUMOR-CELLS AND THEIR CROSS-RESISTANCE TO 6-THIOGUANINE
-
MODULATION OF P-GLYCOPROTEIN-MEDIATED MULTIDRUG-RESISTANCE BY MONOCLONAL-ANTIBODIES, IMMUNOTOXINS OR ANTISENSE OLIGODEOXYNUCLEOTIDES IN KIDNEY CARCINOMA AND NORMAL KIDNEY-CELLS
-
REVERSAL OF INHERENT MULTIDRUG-RESISTANCE IN PRIMARY HUMAN RENAL-CELL CARCINOMA CELL-CULTURES BY S-9788
-
REVERSAL OF DOXORUBICIN-RESISTANCE IN SARCOMA-180 TUMOR-CELLS BY INHIBITION OF DIFFERENT RESISTANCE MECHANISMS
-
EXPRESSION OF PROTEIN-KINASE-C IN HUMAN RENAL-CELL CARCINOMA-CELLS WITH INHERENT RESISTANCE TO DOXORUBICIN
-
HIGH-RATE OF EXPRESSION OF MULTIDRUG RESISTANCE-ASSOCIATED P-GLYCOPROTEIN IN HUMAN ENDOMETRIAL CARCINOMA AND NORMAL ENDOMETRIAL TISSUE
-
EXPRESSION OF RESISTANCE FACTORS (P-GLYCOPROTEIN, GLUTATHIONE-S-TRANSFERASE-PI, AND TOPOISOMERASE-II) AND THEIR INTERRELATIONSHIP TO PROTOONCOGENE PRODUCTS IN RENAL-CELL CARCINOMAS
-
EXPRESSION OF SEVERAL RESISTANCE MECHANISMS IN UNTREATED HUMAN KIDNEY AND LUNG CARCINOMAS
-
RESISTANCE MECHANISMS IN MURINE TUMORS WITH ACQUIRED MULTIDRUG RESISTANCE
-
OVEREXPRESSION OF C-FOS AND C-ERBB1 ENCODED PROTEINS IN SQUAMOUS-CELL CARCINOMAS OF THE LUNG OF SMOKERS
-
IMMUNOCYTOCHEMICAL DETECTION OF ONCOPROTEINS IN ANIMAL AND HUMAN TUMOR LINES WITH ACQUIRED OR INHERENT MULTIDRUG RESISTANCE
-
ANTIBODY-DIRECTED THERAPY OF MULTIDRUG-RESISTANT TUMOR-CELLS
-
ONCOPROTEIN (C-MYC, C-ERBB1, C-ERBB2, C-FOS) AND SUPPRESSOR GENE-PRODUCT (P53) EXPRESSION IN SQUAMOUS-CELL CARCINOMAS OF THE LUNG - CLINICAL AND BIOLOGICAL CORRELATIONS
-
IMMUNOHISTOCHEMICAL DETECTION OF P-GLYCOPROTEIN, GLUTATHIONE-S-TRANSFERASE AND DNA TOPOISOMERASE-II IN HUMAN TUMORS
-
CIRCUMVENTION OF MULTIDRUG RESISTANCE IN HUMAN KIDNEY AND KIDNEY CARCINOMA INVITRO
-
SELECTIVE GROWTH-INHIBITION OF MULTIDRUG-RESISTANT CHO-CELLS BY THE MONOCLONAL-ANTIBODY 265/F4
-
OVEREXPRESSION OF P-GLYCOPROTEIN IN HUMAN LUNG-CARCINOMA XENOGRAFTS AFTER FRACTIONATED-IRRADIATION INVIVO
-
RESISTANCE TO DOXORUBICIN IN TUMOR-CELLS INVITRO AND INVIVO AFTER PRETREATMENT WITH VERAPAMIL
-
REVERSING MULTIDRUG RESISTANCE IN L1210 TUMOR-CELLS BY HYCANTHONE OR CHLOROPHENOXAMINE INVITRO AND INVIVO
-
DETECTION OF DRUG-RESISTANCE AND P-GLYCOPROTEIN IN HUMAN RENAL-CELL CARCINOMAS
-
OVEREXPRESSION OF P-GLYCOPROTEIN IN RAT HEPATOCELLULAR CARCINOMAS INDUCED WITH N-NITROSOMORPHOLINE
-
RELATIONSHIP OF DNA PLOIDY TO CHEMORESISTANCE OF TUMORS AS MEASURED BY INVITRO TESTS
-
CORRELATIONS BETWEEN NATURAL-RESISTANCE TO DOXORUBICIN, PROLIFERATIVE ACTIVITY, AND EXPRESSION OF P-GLYCOPROTEIN-170 IN HUMAN KIDNEY TUMOR-CELL LINES
-
DETECTION OF THE MULTIDRUG RESISTANT PHENOTYPE IN HUMAN-TUMORS BY MONOCLONAL-ANTIBODIES AND THE STREPTAVIDIN BIOTINYLATED PHYCOERYTHRIN COMPLEX METHOD
-
ACQUIRED DRUG-RESISTANCE IN HUMAN-LUNG CARCINOMA XENOGRAFTS
-
DETECTION OF P-GLYCOPROTEIN IN HUMAN LEUKEMIAS USING MONOCLONAL-ANTIBODIES
-
DETECTION OF DRUG-RESISTANCE IN HUMAN OVARIAN-CARCINOMA
-
INDUCED MULTIDRUG RESISTANCE IN MURINE LEUKEMIA-L1210 AND ASSOCIATED CHANGES IN A SURFACE-MEMBRANE GLYCOPROTEIN
-
INDUCED MULTIDRUG-RESISTANCE IN MURINE SARCOMA 180 CELLS GROWN-INVITRO AND INVIVO AND ASSOCIATED CHANGES IN EXPRESSION OF MULTIDRUG-RESISTANCE DNA-SEQUENCES AND MEMBRANE-GLYCOPROTEINS
-
RAPID DETECTION ASSAYS FOR MULTIDRUG RESISTANCE
-
IMMUNOCYTOCHEMICAL DETECTION OF A RESISTANCE-ASSOCIATED GLYCOPROTEIN IN TISSUE-CULTURE CELLS, ASCITES TUMORS AND HUMAN-TUMOR XENOGRAFTS BY MAB 265 F4
-
DETECTION OF MURINE S180 CELLS EXPRESSING A MULTIDRUG RESISTANCE PHENOTYPE USING DIFFERENT INVITRO TEST SYSTEMS AND A MONOCLONAL-ANTIBODY
-
Breaking the spores of the fungus Ganoderma lucidum by supercritical CO2
-
The impact of "omics" technologies for grapevine (Vitis vinifera) research
-
Tumor preventive properties of selected marine pigments against colon and breast cancer
-
Shikonin impairs the growth of docetaxel-resistant prostate cancer cells by necroptosis.
-
Artesunate reduces tumor growth and induces different kinds of cell death in docetaxel-resistant prostate carcinoma cells
-
Cytotoxic polyoxygenated isopimarane diterpenoids from the edible rhizomes of Kaempferia galanga (kencur)
-
Synthesis of novel xanthone and acridone carboxamides with potent antiproliferative activities
-
The new journal Phytomedicine Plus to meet the increasing demand for publishing in the fields of phytotherapy and phytopharmacology
-
Medicinal plants and phytochemicals against multidrug-resistant tumor cells expressing ABCB1, ABCG2, or ABCB5: a synopsis of 2 decades
-
Two new flavonoids from Dracaena usambarensis Engl.
-
Multifactorial anti-inflammatory activity of STW5-II towards murine intestinal organoids
-
New phenolics, cytotoxicity and chemosystematic significance of Atriplex semibaccata
-
Interviews and personal stories: A humanities approach in pharmaceutical education
-
Gastroprotective effects of ursolic acid isolated from Ochrosia elliptica on ethanol-induced gastric ulcer in rats
-
Artesunate reduces tumor growth in sunitinb-resistant renal cell carcinoma cells
-
ANTI-INFLAMMATORY AND EPITHELIAL PROTECTIVE EFFECTS OF HERBAL PREPARATION STW5-II ON MOUSE INTESTINAL ORGANOIDS
-
Biotechnology Applications of Plant Callus Cultures
-
Euonymus maackii Rupr. Seed oil as a new potential non-edible feedstock for biodiesel
-
Beyond malaria: Second career of artesunate as cancer drug
-
Catalytic transesterification of Pistacia chinensis seed oil using HPW immobilized on magnetic composite graphene oxide/cellulose microspheres
-
Phytochemical constituents and chemosystematic significance of Pulicaria jaubertii E.Gamal-Eldin (Asteraceae)
-
Heterocycles 44. Synthesis, characterization and anticancer activity of new thiazole ortho-hydroxychalcones
-
Polyphenolic compounds, antioxidant and anti-inflammatory effects of Abeliophyllum distichum Nakai extract
-
The anticancer activity of the antimalarial artesunate
-
Improvement of resveratrol production from waste residue of grape seed by biotransformation of edible immobilized Aspergillus oryzae cells and negative pressure cavitation bioreactor using biphasic ionic liquid aqueous system pretreatment
-
Neuroprotection and antioxidative effects of Sijunzi Tang Decoction in the nematode Caenorhabditis elegans
-
Shikonin causes cancer cell death by inducing mitochondria! dysfunction
-
Fishing for artemisin-ininteracting proteins from human nasopharyngeal cancer cells
-
Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells
-
Synthesis and Cytotoxicity of 1,4-Dihydropyridines and an Unexpected 1,3-Oxazin-6-one
-
Correlation of cultivation time of Panax ginseng with metabolic profiles of nine ginsenosides and mRNA expression of genes encoding major biosynthetic enzymes
-
Negative-pressure cavitation coupled with aqueous two-phase extraction and enrichment of flavonoids and stilbenes from the pigeon pea leaves and the evaluation of antioxidant activities
-
Discovering New Underlying Mechanisms in the Treatment of Functional Dyspepsia With the Herbal Preparation, STW5 Using a Novel Sequential Stress Model
-
Receptor Modulation and MAP-Kinase Signaling Induced by STW5 and by the Proton-Pump Inhibitor Omeprazol in a Rat Model for Gastroesophageal Reflux Disease and in HET1A-Cells
-
Ethylene increases accumulation of compatible solutes and decreases oxidative stress to improve plant tolerance to water stress in Arabidopsis
-
Modulation of the pharmacokinetics, therapeutic and adverse effects of NSAIDs by Chinese herbal medicines
-
INHIBITION OF P-GLYCOPROTEIN IN CANCER CELLS BY SYNTHETIC AND NATURAL COMPOUNDS
-
Phytochemicals for the treatment of inflammatory bowel diseases
-
Free radical scavenging capability, antioxidant activity and chemical constituents of Pyrola incarnata Fisch leaves
-
Antioxidant properties, superoxide dismutase and glutathione reductase activities in HepG2 cells with a fungal endophyte producing apigenin from pigeon pea [Cajanus cajan (L.) Millsp.]
-
Enzyme pretreatment and negative pressure cavitation extraction of genistein and apigenin from the roots of pigeon pea [Cajanus cajan (L.) Millspl and the evaluation of antioxidant activity
-
Potential of 'Omics' Technologies for Implementation in Research on Phytotherapeutical Toxicology
-
Molecular approaches for individualized tumor therapy with standard drugs, phytochemicals, and medicinal herbs
-
Enhanced extraction of isoflavonoids from Radix Astragali by incubation pretreatment combined with negative pressure cavitation and its antioxidant activity
-
Negative pressure cavitation accelerated processing for extraction of main bioactive flavonoids from Radix Scutellariae
-
Resin adsorption as a means to enrich rare stilbenes and coumarin from pigeon pea leaves extracts
-
Preparation and antioxidant activity of Radix Astragali residues extracts rich in calycosin and formononetin
-
Negative-pressure cavitation extraction of cajaninstilbene acid and pinostrobin from pigeon pea [Cajanus cajan (L.) Millsp.] leaves and evaluation of antioxidant activity
-
Virtual screening of small molecule inhibitors towards the tumor suppressor p53 to overcome radioresistance of nasopharyngeal carcinoma cells
-
Enzymatic water extraction of taxifolin from wood sawdust of Larix gmelini (Rupr.) Rupr. and evaluation of its antioxidant activity
-
Negative pressure cavitation extraction and antioxidant activity of genistein and genistin from the roots of pigeon pea [Cajanus cajan (L.) Millsp.]
-
Rapid microwave-assisted transesterification for the preparation of fatty acid methyl esters from the oil of yellow horn (Xanthoceras sorbifolia Bunge.)
-
Antimicrobial activity and cytotoxicity towards cancer cells of Melaleuca alternifolia (tea tree) oil
-
Immunohistological detection of P-glycoprotein 170 in multidrug resistant cells
-
P-GLYCOPROTEIN AS MARKER FOR MULTIDRUG-RESISTANCE IN TUMORS AND NORMAL-TISSUES
-
CLINICAL RELEVANCE OF THE MDR-1 GENE AND ITS GENE-PRODUCT, P-GLYCOPROTEIN, FOR CANCER-CHEMOTHERAPY - A METAANALYSIS
-
Curcumin Shows Promising Anti-Tumor Effects in Mice, at Least
-
Quality management for biomedical research in Germany
-
Didactics of molecular ecology
-
IS THERE A REALISTIC CHANCE FOR THE CLINICAL MODULATION OF MULTIDRUG-RESISTANCE
-
Artesunate Inhibits the Growth Behavior of Docetaxel-Resistant Prostate Cancer Cells
-
Der Virtuelle Campus Rheinland-Pfalz.
-
Selective growth-inhibition of multidrug-resistant CHO-cells by the monoclonal antibody 265/F4
-
Molekulare Pharmakologie und Toxikologie Biologische Grundlagen von Arzneimitteln und Giften
-
Resistance to Targeted ABC Transporters in Cancer
-
Biodiversity, Natural Products and Cancer Treatment
-
Shikonin Inhibits Cell Growth of Sunitinib-Resistant Renal Cell Carcinoma by Activating the Necrosome Complex and Inhibiting the AKT/mTOR Signaling Pathway
-
In Silico and In Vitro Identification of Pan-Coronaviral Main Protease Inhibitors from a Large Natural Product Library
-
Cancer combination therapy with carnosic acid
-
Plant cell cultures: An enzymatic tool for polyphenolic and flavonoid transformations
-
Fuzi decoction ameliorates pain and cartilage degeneration of osteoarthritic rats through PI3K-Akt signaling pathway and its clinical retrospective evidence
-
Transcriptomics, molecular docking, and cross-resistance profiling of nobiletin in cancer cells and synergistic interaction with doxorubicin upon SOX5 transfection
-
Regulation of endoplasmic reticulum stress by hesperetin: Focus on antitumor and cytoprotective effects
-
Liver and gastrointestinal cancers
-
Individualized Tumor Therapy: Biomarkers and Possibilities for Targeted Therapy with Natural Products
-
Antiproliferative Potential of African Medicinal Plants
-
Naphthoquinone derivatives as P-glycoprotein inducers in inflammatory bowel disease: 2D monolayers, 3D spheroids, and in vivo models
-
Biflavonoids from Ginkgo biloba leaves as a novel anti-atherosclerotic candidate: Inhibition potency and mechanistic analysis
-
Flavanols from Tetrapleura tetraptera with cytotoxic activities
-
Identification of active components in Andrographis paniculata targeting on CD81 in esophageal cancer in vitro and in vivo
-
A saponin from astragalus promotes pancreatic ductal organoids differentiation into insulin-producing cells
-
Protein Expression Profiling and Virtual Drug Screening as an Approach for Individualized Therapy of Small Cell Vaginal Carcinoma
-
Onset of p53/NF-κB signaling crosstalk in human melanoma cells in response to anti-cancer theabrownin
-
Drug targets and resistance mechanisms in multiple myeloma
-
Modulation of Intestinal Corticotropin-Releasing Hormone Signaling by the Herbal Preparation STW 5-II: Possible Mechanisms for Irritable Bowel Syndrome Management
-
Lessons from COVID-19 to increase opioid vaccine acceptance
-
A Multicenter, Single-Blind, Case-Control, Immunohistochemical Study of Orbital Tissue in Thyroid Eye Disease
-
Targeting Angiogenesis By Phytochemicals
-
Editorial: II Bio.natural-bioactive natural products research meeting: Pharmacology perspectives
-
Novel Class of Proteasome Inhibitors: In Silico and In Vitro Evaluation of Diverse Chloro(trifluoromethyl)aziridines
-
Plant extracts and compounds for combating schistosomiasis
-
Network Pharmacology of Ginseng (Part III): Antitumor Potential of a Fixed Combination of Red Ginseng and Red Sage as Determined by Transcriptomics
-
Parvifloron D-based potential therapy for glioblastoma: Inducing apoptosis via the mitochondria dependent pathway
-
Biomarker Expression Profiling in Cervix Carcinoma Biopsies Unravels WT1 as a Target of Artesunate
-
Chemometric discrimination of Hylocereus undulatus from different geographical origins via their metabolic profiling and antidiabetic activity
-
Can Essential Oils Provide an Alternative Adjuvant Therapy for COVID-19 Infections and Pain Management at the Same Time?
-
Antileishmanial Activities of Medicinal Herbs and Phytochemicals In Vitro and In Vivo: An Update for the Years 2015 to 2021
-
Current research in biotechnology: Exploring the biotech forefront
-
A Comparative Evaluation of the Antimicrobial Activities of the Essential Oils of Three Salvia Species Growing in Egypt, Obtained by Hydrodistillation and Microwave-Assisted Hydro-distillation
-
Feature-Based Molecular Networking for the Exploration of the Metabolome Diversity of Common Egyptian Centaurea Species in Relation to Their Cytotoxic Activity
-
Identification of Prognostic and Predictive Biomarkers and Druggable Targets among 205 Antioxidant Genes in 21 Different Tumor Types via Data-Mining
-
Cytotoxicity of the methanol extracts and compounds of Brucea antidysenterica (Simaroubaceae) towards multifactorial drug-resistant human cancer cell lines
-
Phytochemistry, structural diversity, biological activities and pharmacokinetics of iridoids isolated from various genera of the family Scrophulariaceae Juss.
-
Network Pharmacology of Triptolide in Cancer Cells: Implications for Transcription Factor Binding
-
Modulatory Activity of the Copper Chelate, Copper N-(2-Hydroxy Acetophenone) Glycinate, in ABC-transporter-expressing Cell Lines
-
Evidence and rational based research on chinese drugs
-
Phytochemical screening of medicinal plants of the Kakamega Country, Kenya commonly used against Cancer
-
Targeting Angiogenesis by Therapeutic Antibodies
-
Tanshinone Diterpenes: Chemistry and Multifunctional Biological Activities
-
In Vitro and In Silico Studies of Two 1, 4-Naphthoquinones and Their Topical Formulation in Bigels
-
Therapeutic targeting of SNAIL, RKIP, and YY1 in tumor metastasis and drug resistance
-
Integration of Phytochemicals and Phytotherapy into Cancer Precision Medicine
-
Mitosis Inhibitors and Medicinal Plants: Neurotoxicity and Neuroprotection
-
Identification of chemosensitizers by drug repurposing to enhance the efficacy of cancer therapy
-
Anticancer Activity of Salvia miltiorrhiza and Its Secondary Metabolites
-
Lernplattformen–entscheidungen mit weitblick
-
Inhibition of P-glycoprotein by two artemisinin derivatives
-
Activity of artemisinin-type compounds against cancer cells
-
Novel developments on Artemisinin and its derivatives for cancer therapy
-
Bioactivity of Salvia miltiorrhiza and its constituents
-
Teratogenicity and developmental toxicity of herbal products
-
Collateral sensitivity in drug-resistant tumor cells
-
Adaptogens in chemobrain (part IV): Adaptogenic plants prevent the chemotherapeutics-induced imbalance of redox homeostasis by modulation of expression of genes encoding Nrf2-mediated signaling proteins and antioxidant, metabolizing, detoxifying enzymes in neuroglia cells
-
Inverse correlation of epidermal growth factor receptor messenger RNA induction and suppression of anchorage-independent growth by OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in glioblastoma multiforme cell lines
-
Quantitative regulation of melanoma growth in the host by tumor-specific serpins in blood serum is a main reason for inefficient tumor treatment
-
Growth inhibition of human acute lymphoblastic CCRF-CEM leukemia cells by medicinal plants of the West-Canadian Gwich’in Native Americans
-
Herbal Medicines: Boon or Bane for the Human Liver?
-
Phytochemical characterization and biological activities of green tea (Camellia sinensis) produced in the Azores, Portugal
-
Synthesis, Antibacterial and Cytotoxic Activities of Cyanoenonebenzenesulfonamide, Acetamide and Pyridine-3-carbonitrile Derivatives
-
Prognostic and Therapeutic Applications of RKIP in Cancer
-
The antimalarial artesunate is also a potent anticancer drug
-
2$\prime$ O-galloylhyperin attenuates LPS-induced acute lung injury via up-regulation antioxidation and inhibition of inflammatory responses in vivo
-
Pharmaceutical biology of traditional Chinese medicine for cancer therapy
-
High TCTP expression as prognostic factor in different cancer types
-
Chemical-biology of natural products from medicinal plants for cancer therapy
-
Pharmacogenomics of Biotic and Abiotic Natural Products Derived from Traditional Chinese Medicine for Cancer Therapy
-
Activation of Mitochondria-Driven Pathways by Artemisinin and Its Derivatives
-
Inhibition of ATP-binding cassette transporters by Chinese herbs and phytochemicals
-
Role of nitric oxide for modulation of cancer therapy resistance
-
Artemisinin: A versatile weapon from traditional Chinese medicine
-
Substanzklassen und Wirkmechanismen
-
Self-medication with nutritional supplements and herbal over-thecounter products
-
Seminars in cancer biology
-
Development of drug resistance in Trichomonas vaginalis and its overcoming with natural products
-
Antiviral medicinal herbs and phytochemicals
-
Overcoming of P-glycoprotein-mediated multidrug resistance of tumors in vivo by drug combinations
-
Expression of the multidrug-resistance gene product P-glycoprotein in gynecological tumors
-
Coronaviral ion channels as target for Chinese herbal medicine
-
Evaluation of quality of life in patients treated with traditional Chinese medicine
-
Ayurveda for cancer treatment
-
Expanding the therapeutic spectrum of artemisinin: Activity against infectious diseases beyond malaria and novel pharmaceutical developments
-
Artemisinin–second career as anticancer drug?
-
Second career for grayanotoxins?
-
Medicinal plants and DNA methylation of cancer
-
Medicinal and aromatic plant research in the 21st century
-
Quality control for medicinal plants
-
Polyphenols-Versatile Weapons in Plants and Human Beings
-
E-learning in pharmacology and pharmacy
-
Perspectives for globalized natural medicines
-
Preface: Molecular Approaches of Chinese Medicine
-
Therapeutic Intervention of Post-traumatic Stress Disorder by Chinese Medicine: Perspectives for Transdisciplinary Cooperation between Life Sciences and Humanities
-
Doctrine of signatures-mystic heritage or outdated relict from middle-aged phytotherapy
-
Impact of Plastic-Related Compounds on P-Glycoprotein and Breast Cancer Resistance Protein In Vitro
-
Parvifloron D-based therapy for glioblastoma: targeting tumor microenvironment with a natural drug lead
-
Anti-inflammatory and epithelial protective effects of herbal preparation STW5-II on mouse intestinal organoids
-
Strategies to assess drug interactions in oncology
-
The application of TCM to the treatment of psychiatry diseases: in vitro anti-oxidation and anti-inflammatory effect of Free and Easy Wanderer
-
Chrysophanol- and nepodin-8-O-β-D-glucopyranoside from Rumex acetosella, the cytotoxicity towards drug sensitive and multi- drug resistant T leukaemia cancer cells
-
Chemical characterisation and cytotoxicity evaluation of Convolvulus pluricaulis Sieb. ex Spreng. (Convolvulaceae) extracts towards sensitive and multidrug-resistant cancer cells
-
Supporting evidence for the potential usefulness of the herbal preparation STW 5 in an experimental model of Crohn's disease
-
Two new genetic mouse models for ulcerative colitis based on lateral tight junction disruption.
-
The anti-inflammatory action of the herbal preparation STW5-II in normal human colonic mucosal cells
-
Preservation of gastric functional activity in a novel stress model of functional dyspepsia by the herbal preparation, STW5
-
Beyond acid insult: TREM-1 signalling and lipid-receptors contribute to the pathogenesis of reflux oesophagitis
-
Novel mechanisms underlying the effectiveness of the herbal preparation, STW 5, in functional dyspepsia
-
The Eucalyptus oil ingredient 1,8-cineol induces oxidative DNA damage
-
Disruption of phosphatidylcholine paracellular movement to intestinal mucus predisposes to Ulcerative Colitis
-
Identification of mitochondrial and PI3K-Akt-mTOR pathways as targets of naphtoquinones in cancer cells by pharmacogenomics
-
Understanding adaptogens: new evidence on their possible effectiveness in stress-induced and ageing-associated disorders from a DNA microarray study of neuroglia cells
-
Artenimol-R in advanced cervical cancer
-
Interactions of Chinese medicine with standard treatments
-
Modulation of P-glycoprotein, cytochrome P450, and glutathione-S-transferase by resveratrol in human cancer cells
-
Digitonin reverses doxorubicin resistance in cancer cells
-
Natural products derived from traditional chinese medicine as novel inhibitors of the epidermal growth factor receptor in cancer cells
-
The influence of the TCM drug artesunate on the sensitivity of tumor cell lines and his cytotoxic an genotoxic activity
-
Genome-scale microRNA identify small RNA modulators of the effect of berberine on pancreatic cancer cell growth
-
Effects of dimethylacrylshikonin and epoxyshikonin on melanoma cell lines
-
Inhibition of P-glycoprotein, cytochrome P450, and glutathione-S-transferase in human cancer cells by Polygonium cuspidatum
-
Approaches for the integration of phytochemicals into classical cancer chemotherapy by modulation of multi-factorial drug resistance
-
The TCM drug artesunate induces DNA damage in glioblastoma cells
-
Expression profiling and network-based analysis for the effect of curcumin on pancreatic cancer cells
-
Thai medicinal plants and the search for new anti-inflammatory and anticancer agents
-
A petrol ether extract of Onosma paniculatum Bur. & Franch. shows strong anti-proliferative activity and induces apoptosis in human cancer cell lines
-
Inhibition of P-glycoprotein at the blood brain barrier by phytochemicals derived from traditional Chinese medicine
-
Workshops for Young Researchers: Cell Culture
-
From the Bench to the Bedside: How Natural Products Can Find Their Way
-
Anticancer, NF-κB inhibitory and antioxidant properties of Thai traditional anti-inflammatory plants
-
Anti-leukemic activity-guided fractionation of Mammea siamensis flowers
-
Molecular interactions of artemisinin with DNA and specific target proteins in cancer cells
-
Artesunate mediates growth inhibitory effects in human pancreatic cancer cells through modulation of multiple signalling pathways
-
Anti-inflammatory and anti-oxidant activity of six Cistus species
-
Grayanotoxin III shows microtubule-targeted activity
-
In vitro cytotoxicity and p-glycoprotein modulating effects of geranylated furocournarins from Tetradium daniellii
-
Molecular mechanism of action of stilbene compounds from Cajanus cajan leaves in cancer cell lines
-
Anti-inflammatory and anti-leukemic activities of the flower extracts from Thai medicinal plants
-
Molecular mechanism of action of the flavanone pinostrobin from Cajanus cajan leaves in cancer cells
-
From molecular diagnostics to molecular targeted therapy with natural product small molecule inhibitors in oral squamous cell carcinoma
-
Artesunate as a potent anti-CMV agent in a patient after mismatched haematopietic cell transplantation
-
Artemisinin derivatives induce generation of nitric oxide and reactive oxygen species in cell lines of hematopoietic origin
-
In silica screening and experimental validation of novel inhibitors of nitric oxide from a database of natural products derived from traditional chinese medicine
-
Stilbenes from Cajanus cajan engage apoptotic signals in acute human T-lymphoblastic leukaemia cell lines
-
Additive antiviral effect of artemisinin and ribavirin on an "in vitro" model of hepatitis C infection
-
Inhibition of tumor angiogenesis in vitro and in vivo by the anti-malarial artesunate
-
Expression profiling of ATP-binding cassette (ABC) transporter genes by a low density microarray to detect drug resistance of tumors
-
ABCChips as new diagnostic tool to monitoring multidrug resistance in human tumor cells to chemotherapeutics agents by expression profiling of ATP-binding cassette transporter genes.
-
Expression profiling of ABC-transporters in childhood AML reveals ABCA3 as a potential cause of drug resistance.
-
Biological activity of plant extracts in medullary thyroid carcinoma
-
Molecular modes of action of antimalarial artemisinin derivatives as novel anticancer drugs
-
The antimalarial artesunate acts also as a potent anticancer drug via both p53-dependent and -independent pathways
-
Xylochemical Synthesis and Biological Evaluation of the Orchidaceous Natural Products Isoarundinin I, Bleochrin F, Blestanol K, and Pleionol
-
Molecular Modes of Action of an Aqueous Nerium oleander Extract in Cancer Cells In Vitro and In Vivo
-
The Novel Artemisinin Dimer Isoniazide ELI-XXIII-98-2 Induces c-MYC Inhibition, DNA Damage, and Autophagy in Leukemia Cells
-
Modes of Action of a Novel c-MYC Inhibiting 1,2,4-Oxadiazole Derivative in Leukemia and Breast Cancer Cells
-
A whole-genome scan for Artemisinin cytotoxicity reveals a novel therapy for human brain tumors
-
The antiviral activities of artemisinin and artesunate
-
Leishmaniasis: Drug resistance and natural products (Review)
-
Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo
-
The Impact of Artificial Intelligence on Traditional Chinese Medicine
-
Cytotoxic phytochemicals from the crude extract of Tetrapleura tetraptera fruits towards multi-factorial drug resistant cancer cells
-
Cytotoxic and chemotaxonomic study of isolated metabolites fromCentaurea aegyptiaca
-
Artesunate as a potent antiviral agent in a patient with late drug-resistant cytomegalovirus infection after hematopoietic stem cell transplantation
-
Artesunate Induces ROS-Mediated Apoptosis in Doxorubicin-Resistant T Leukemia Cells
-
Molecular docking-based virtual drug screening revealing an oxofluorenyl benzamide and a bromonaphthalene sulfonamido hydroxybenzoic acid as HDAC6 inhibitors with cytotoxicity against leukemia cells
-
Cytotoxicity of a naturally occuring spirostanol saponin, progenin III, towards a broad range of cancer cell lines by induction of apoptosis, autophagy and necroptosis
-
Application of integrative cloud point extraction and concentration for the analysis of polyphenols and alkaloids in mulberry leaves
-
Nanocarriers to enhance solubility, bioavailability, and efficacy of artemisinins
-
Organophosphate ester tri-o-cresyl phosphate interacts with estrogen receptor α in MCF-7 breast cancer cells promoting cancer growth
-
Novel secondary metabolites from endophytic fungi: synthesis and biological properties
-
Therapeutic potential of polyphenols in cardiovascular diseases: Regulation of mTOR signaling pathway
-
Collateral sensitivity of natural products in drug-resistant cancer cells
-
Cytotoxicity of the crude extract and constituents of the bark of Fagara tessmannii towards multi-factorial drug resistant cancer cells
-
A selective inhibitor of the Polo-box domain of Polo-like kinase 1 identified by virtual screening
-
Long-term add-on therapy (compassionate use) with oral artesunate in patients with metastatic breast cancer after participating in a phase I study (ARTIC M33/2)
-
Cytotoxicity of fagaramide derivative and canthin-6-one from Zanthoxylum (Rutaceae) species against multidrug resistant leukemia cells
-
Cytotoxicity of cucurbitacin E from Citrullus colocynthis against multidrug-resistant cancer cells
-
Hepatoprotective and anti-inflammatory effects of total flavonoids of Qu Zhi Ke (peel of Citrus changshan-huyou) on non-alcoholic fatty liver disease in rats via modulation of NF-κB and MAPKs
-
The pharmacology of the genus Sophora (Fabaceae): An updated review
-
Euphosantianane A-D: Antiproliferative Premyrsinane Diterpenoids from the Endemic Egyptian Plant Euphorbia Sanctae-Catharinae
-
Repurposing of Bromocriptine for Cancer Therapy
-
Pharmacogenomic Characterization and Isobologram Analysis of the Combination of Ascorbic Acid and Curcumin-Two Main Metabolites of Curcuma longa-in cancer Cells
-
Cytotoxicity of methanol extracts of 10 Cameroonian medicinal plants towards multi-factorial drug-resistant cancer cell lines
-
A naturally occuring triterpene saponin ardisiacrispin B displayed cytotoxic effects in multi-factorial drug resistant cancer cells via ferroptotic and apoptotic cell death
-
Cytotoxicity of 18 Cameroonian medicinal plants against drug sensitive and multi-factorial drug resistant cancer cells
-
Multiple resistance to carcinogens and xenobiotics: P-glycoproteins as universal detoxifiers
-
Prospective open uncontrolled phase I study to define a well-tolerated dose of oral artesunate as add-on therapy in patients with metastatic breast cancer (ARTIC M33/2)
-
Antiproliferative activity against leukemia cells of sesquiterpene lactones from the Turkish endemic plant Centaurea drabifolia subsp detonsa
-
Potential of Central, Eastern and Western Africa Medicinal Plants for Cancer Therapy: Spotlight on Resistant Cells and Molecular Targets
-
Ginkgolic acids inhibit migration in breast cancer cells by inhibition of NEMO sumoylation and NF-κB activity
-
Reversal of multidrug resistance by Marsdenia tenacissima and its main active ingredients polyoxypregnanes
-
Cytotoxic benzylbenzofuran derivatives from Dorstenia kameruniana
-
P-glycoprotein and its inhibition in tumors by phytochemicals derived from Chinese herbs
-
Cytotoxicity of compounds from Xylopia aethiopica towards multi-factorial drug-resistant cancer cells
-
Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells
-
Synergy assessment of fixed combinations of Herba Andrographidis and Radix Eleutherococci extracts by transcriptome-wide microarray profiling
-
Anti-leukemia activity of semi-synthetic phenolic derivatives from Polygonum limbatum Meisn
-
Cytotoxicity and modes of action of 4′-hydroxy-2′,6′-dimethoxychalcone and other flavonoids toward drug-sensitive and multidrug-resistant cancer cell lines
-
Phytochemical Analysis and Cytotoxicity Towards Multidrug-Resistant Leukemia Cells of Essential Oils Derived from Lebanese Medicinal Plants
-
Aqueous enzymatic process assisted by microwave extraction of oil from yellow horn (Xanthoceras sorbifolia Bunge.) seed kernels and its quality evaluation
-
Dryofragin, a phloroglucinol derivative, induces apoptosis in human breast cancer MCF-7 cells through ROS-mediated mitochondrial pathway
-
Stem Cells, Cancer Stem-Like Cells, and Natural Products
-
Antibacterial Activity and Anticancer Activity of Rosmarinus officinalis L. Essential Oil Compared to That of Its Main Components
-
Cytotoxicity and Mode of Action of Four Naturally Occuring Flavonoids from the Genus Dorstenia: Gancaonin Q, 4-Hydroxylonchocarpin, 6-Prenylapigenin, and 6,8-Diprenyleriodictyol
-
Cytotoxic flavonoids and isoflavonoids from Erythrina sigmoidea towards multi-factorial drug resistant cancer cells
-
Cytotoxicity of four Aframomum species (A. arundinaceum, A. alboviolaceum, A. kayserianum and A. polyanthum) towards multi-factorial drug resistant cancer cell lines
-
Activity of three cytotoxic isoflavonoids from Erythrina excelsa and Erythrina senegalensis (neobavaisoflavone, sigmoidin H and isoneorautenol) toward multi-factorial drug resistant cancer cells
-
Cytotoxicity and modes of action of three naturally occurring xanthones (8-hydroxycudraxanthone G, morusignin I and cudraxanthone I) against sensitive and multidrug-resistant cancer cell lines
-
A conceptually new treatment approach for relapsed glioblastoma: Coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care.
-
Cytotoxicity of some Cameroonian spices and selected medicinal plant extracts
-
Artesunate Activates Mitochondrial Apoptosis in Breast Cancer Cells via Iron-catalyzed Lysosomal Reactive Oxygen Species Production
-
Cajanol Inhibits the Growth of Escherichia coli and Staphylococcus aureus by Acting on Membrane and DNA Damage
-
African Flora Has the Potential to Fight Multidrug Resistance of Cancer
-
Cytotoxic Compounds from the Fruits of Uapaca togoensis towards Multifactorial Drug-Resistant Cancer Cells
-
Anticancer activities of six selected natural compounds of some Cameroonian medicinal plants
-
Combination treatment of malignant B cells using the anti-CD20 antibody rituximab and the anti-malarial artesunate
-
Molecular principles of cancer invasion and metastasis (Review)
-
Simultaneous determination of main taxoids in Taxus needles extracts by solid-phase extraction-high-performance liquid chromatography with pentafluorophenyl column
-
Cajanol, a novel anticancer agent from Pigeonpea [Cajanus cajan (L.) Millsp.] roots, induces apoptosis in human breast cancer cells through a ROS-mediated mitochondrial pathway
-
Traditionally used Thai medicinal plants: In vitro anti-inflammatory, anticancer and antioxidant activities
-
Antioxidant Activities and Xanthine Oxidase Inhibitory Effects of Extracts and Main Polyphenolic Compounds Obtained from Geranium sibiricum L.
-
Supercritical carbon dioxide extraction of seed oil from yellow horn (Xanthoceras sorbifolia Bunge.) and its anti-oxidant activity
-
Chemical composition and biological activities of Artemisia judaica essential oil from southern desert of Jordan
-
Artemisia herba-alba essential oil from Buseirah (South Jordan): Chemical characterization and assessment of safe antifungal and anti-inflammatory doses
-
Signal Transduction Pathways of the Epidermal Growth Factor Receptor in Colorectal Cancer and their Inhibition by Small Molecules
-
Quinones and Benzophenones from the Medicinal Plants of Africa
-
Tanshinol suppresses osteosarcoma by specifically inducing apoptosis of U2-OS cells through p53-mediated mechanism
-
Artificial intelligence-directed acupuncture: a review
-
Identification of Gedunin from a Phytochemical Depository as a Novel Multidrug Resistance-Bypassing Tubulin Inhibitor of Cancer Cells
-
Expression of Chemoresistance-Associated ABC Proteins in Hepatobiliary, Pancreatic and Gastrointestinal Cancers
-
Expression of the Stem Cell Marker ABCB5 in Normal and Tumor Tissues
-
The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis
-
Seed oil of Rosa roxburghii Tratt against non-alcoholic fatty liver disease in vivo and in vitro through PPARα/PGC-1α-mediated mitochondrial oxidative metabolism
-
Antileukemia Activity and Mechanism of Platinum(II)-Based Metal Complexes
-
Disruption of Lipid Raft Microdomains, Regulation of CD38, TP53, and MYC Signaling, and Induction of Apoptosis by Lomitapide in Multiple Myeloma Cells
-
Medicinal Chemistry of Paclitaxel and its Analogues
-
Induction of apoptosis, depletion of glutathione, and DNA damage by extracorporeal photochemotherapy and psoralen with exposure to UV light in vitro
-
p53 expression in Wilms' tumor:: A possible role as prognostic factor
-
In Silico, In Vitro, and In Vivo Investigations on Adapalene as Repurposed Third Generation Retinoid against Multiple Myeloma and Leukemia
-
Phytochemistry and bioactivities of the main constituents of Polyporus umbellatus (Pers.) Fries
-
Life sciences—life writing : PTSD as a transdisciplinary entity between biomedical explanation and lived experience
-
Health(care) in the Crisis: Reflections in Science and Society on Opioid Addiction
-
First Nations Healing: From Traditional Medicine to Experimental Ethnopharmacology
-
N-BENZYLADRIAMYCIN-14-VALERATE VERSUS PROGRESSIVELY DOXORUBICIN-RESISTANT MURINE TUMORS - CELLULAR PHARMACOLOGY AND CHARACTERIZATION OF CROSS-RESISTANCE INVITRO AND INVIVO
-
Ursolic acid enhances stress resistance, reduces ROS accumulation and prolongs life span in C. elegans serotonin-deficient mutants
-
Cytotoxicity of sesquiterpene alkaloids from Nuphar plants toward sensitive and drug-resistant cell lines
-
The prophylactic effect of a Eugenia aquea extract against oxidative stress and inflammation associated with the development of arthritis in an adjuvant-induced arthritis rat model
-
The protective role of Ocimum basilicum L. (Basil) against aspirin-induced gastric ulcer in mice: Impact on oxidative stress, inflammation, motor deficits and anxiety-like behavior
-
Ancistrocyclinones A and B, unprecedented pentacyclic N,C-coupled naphthylisoquinoline alkaloids, from the Chinese liana Ancistrocladus tectorius
-
Chemoresistance and chemosensitization in cholangiocarcinoma
-
An effective negative pressure cavitation-microwave assisted extraction for determination of phenolic compounds in P. calliantha H. Andr.
-
Bioinformatic and experimental fishing for artemisinin-interacting proteins from human nasopharyngeal cancer cells
-
Isopetasin and S-isopetasin as novel P-glycoprotein inhibitors against multidrug-resistant cancer cells
-
SERCA and P-glycoprotein inhibition and ATP depletion are necessary for celastrol-induced autophagic cell death and collateral sensitivity in multidrug-resistant tumor cells
-
Repurposing of plant alkaloids for cancer therapy: Pharmacology and toxicology
-
The emergence of drug resistance to targeted cancer therapies: Clinical evidence
-
The alkaloid, soyauxinium chloride, displays remarkable cytotoxic effects towards a panel of cancer cells, inducing apoptosis, ferroptosis and necroptosis
-
Synthesis of Thymoquinone-Artemisinin Hybrids: New Potent Antileukemia, Antiviral, and Antimalarial Agents
-
Target Identification of Active Constituents of Shen Qi Wan to Treat Kidney Yang Deficiency Using Computational Target Fishing and Network Pharmacology
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Cytotoxicity of ungeremine towards multi-factorial drug resistant cancer cells and induction of apoptosis, ferroptosis, necroptosis and autophagy
-
Cytotoxicity of selected Cameroonian medicinal plants and Nauclea pobeguinii towards multi-factorial drug-resistant cancer cells
-
Cytotoxicity of two naturally occurring flavonoids (dorsmanin F and poinsettifolin B) towards multi-factorial drug-resistant cancer cells
-
Cytochrome P450 reaction phenotyping and inhibition and induction studies of pinostrobin in human liver microsomes and hepatocytes
-
Pharmacogenetics and Pharmacotherapy of Military Personnel Suffering from Post-traumatic Stress Disorder
-
Cytotoxicity of seven naturally occurring phenolic compounds towards multi-factorial drug-resistant cancer cells
-
Phytochemical and pharmacological properties of essential oils from Cedrus species
-
A Survey of Chinese Medicinal Herbal Treatment for Chemotherapy-Induced Oral Mucositis
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Nitensidine A, a guanidine alkaloid from Pterogyne nitens, induces osteoclastic cell death
-
Daedalea gibbosa substances inhibit LPS-induced expression of NOS by suppression of NF-κB and MAPK activities in RAW 264.7 macrophage cells
-
Activities of Ten Essential Oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 Cancer Cells
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Human cytomegalovirus kinetics following institution of artesunate after hematopoietic stem cell transplantation
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Effects of artesunate on cytokinesis and G₂/M cell cycle progression of tumour cells and budding yeast.
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Role of antioxidant genes for the activity of artesunate against tumor cells
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Effect of artemisinins and other endoperoxides on nitric oxide-related signaling pathway in RAW 264.7 mouse macrophage cells
-
Prediction of broad spectrum resistance of tumors towards anticancer drugs
-
Evidence-based Chinese medicine for cancer therapy
-
Investigation of antibacterial activity of rosemary essential oil against propionibacterium acnes with atomic force microscopy
-
Prediction of Drug Sensitivity and Resistance of Cancer by Protein Expression Profiling.
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P-GLYCOPROTEIN EXPRESSION IN TREATED AND UNTREATED HUMAN-BREAST CANCER
-
Sarcoehrenbergilides D-F: cytotoxic cembrene diterpenoids from the soft coral Sarcophyton ehrenbergi
-
Synthesis and in vitro biological evaluation of novel diaminothiophene scaffolds as antitumor and antiinfluenza virus agents. Part
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Network Pharmacology of Adaptogens in the Assessment of Their Pleiotropic Therapeutic Activity
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Cytotoxicity, acute and sub-chronic toxicities of the fruit extract of Tetrapleura tetraptera (Schumm. & Thonn.) Taub. (Fabaceae)
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Biomarker Profiling Revealed Carcinoembryonic Antigen as a Target of Artesunate in a Ductal Breast Cancer Patient
-
Phytochemicals with activity against methicillin-resistant Staphylococcus aureus
-
Green tea-derived theabrownin suppresses human non-small cell lung carcinoma in xenograft model through activation of not only p53 signaling but also MAPK/JNK signaling pathway
-
Role of medicinal plants in inhibiting SARS-CoV-2 and in the management of post-COVID-19 complications
-
Rethinking Subthreshold Effects in Regulatory Chemical Risk Assessments
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Untapping the protective role of carotenoids against respiratory diseases
-
Natural medicine HLXL targets multiple pathways of amyloid-mediated neuroinflammation and immune response in treating alzheimer's disease
-
Aucubin as a natural potential anti-acute hepatitis candidate: Inhibitory potency and hepatoprotective mechanism
-
Phytochemical Study and Antiglioblastoma Activity Assessment of Plectranthus hadiensis (Forssk.) Schweinf. ex Sprenger var. hadiensis Stems
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Medicinal plants and their secondary metabolites in alleviating knee osteoarthritis: A systematic review
-
The immunosuppressive activity of artemisinin-type drugs towards inflammatory and autoimmune diseases
-
In Silico and In Vitro Screening of 50 Curcumin Compounds as EGFR and NF-κB Inhibitors
-
Nimbolide inhibits 2D and 3D prostate cancer cells migration, affects microtubules and angiogenesis and suppresses B-RAF/p.ERK-mediated in vivo tumor growth
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Chemistry and the Potential Antiviral, Anticancer, and Anti-Inflammatory Activities of Cardiotonic Steroids Derived from Toads
-
Growth factors-based beneficial effects of platelet lysate on umbilical cord-derived stem cells and their synergistic use in osteoarthritis treatment
-
Essential oil of Acorus tatarinowii Schott inhibits neuroinflammation by suppressing NLRP3 inflammasome activation in 3 x Tg-AD transgenic mice
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Blue Biotechnology: Computational Screening of Sarcophyton Cembranoid Diterpenes for SARS-CoV-2 Main Protease Inhibition
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Traditional Chinese herbal medicine at the forefront battle against COVID-19: Clinical experience and scientific basis
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Cytotoxicity of apigenin toward multiple myeloma cell lines and suppression of iNOS and COX-2 expression in STAT1-transfected HEK293 cells
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Artesunate Inhibits Growth of Sunitinib-Resistant Renal Cell Carcinoma Cells through Cell Cycle Arrest and Induction of Ferroptosis
-
In silico drug discovery of major metabolites from spices as SARS-CoV-2 main protease inhibitors
-
Synthesis and biological evaluation of antimalarial and antileukemic activity of new C-10 modified artemisinin derivatives
-
Synthesis, computational docking and biological evaluation of celastrol derivatives as dual inhibitors of SERCA and P-glycoprotein in cancer therapy
-
Can eastern wisdom resolve western epidemics? Traditional Chinese medicine therapies and the opioid crisis
-
Chemotherapeutic efficacy of curcumin and resveratrol against cancer: Chemoprevention, chemoprotection, drug synergism and clinical pharmacokinetics
-
Multi-omics approaches to improve malaria therapy
-
Pyrrolizidine alkaloids cause cell cycle and DNA damage repair defects as analyzed by transcriptomics in cytochrome P450 3A4-overexpressing HepG2 clone 9 cells
-
Screening for natural and derived bio-active compounds in preclinical and clinical studies: One of the frontlines of fighting the coronaviruses pandemic
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Identification of novel compounds against three targets of SARS CoV-2 coronavirus by combined virtual screening and supervised machine learning
-
2α-Hydroxyalantolactone from Pulicaria undulata: activity against multidrug-resistant tumor cells and modes of action
-
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
-
Furoquinolines and dihydrooxazole alkaloids with cytotoxic activity from the stem bark of Araliopsis soyauxii
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Enzyme assisted extraction of luteolin and apigenin from pigeonpea [Cajanus cajan (L.) Millsp.] leaves
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Development of drug resistance in Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense.: Treatment of human African trypanosomiasis with natural products (Review)
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From traditional Chinese medicine to rational cancer therapy
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Phytochemical inhibitors of the NLRP3 inflammasome for the treatment of inflammatory diseases
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In Silico Mining of Terpenes from Red-Sea Invertebrates for SARS-CoV-2 Main Protease (Mpro) Inhibitors
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Inhibition of cell migration and induction of apoptosis by a novel class II histone deacetylase inhibitor, MCC2344
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Repurposing old drugs to fight multidrug resistant cancers
-
Bisphenolic compounds alter gene expression in MCF-7 cells through interaction with estrogen receptor α
-
Resveratrol mediated cancer cell apoptosis, and modulation of multidrug resistance proteins and metabolic enzymes
-
Antimicrobial activity of clove and rosemary essential oils alone and in combination
-
Tumor microenvironment and epithelial mesenchymal transition as targets to overcome tumor multidrug resistance
-
Vitamin K3 chloro derivative (VKT-2) inhibits HDAC6, activates autophagy and apoptosis, and inhibits aggresome formation in hepatocellular carcinoma cells
-
Vitamin K3 thio-derivative: a novel specific apoptotic inducer in the doxorubicin-sensitive and -resistant cancer cells
-
Ancistrobreveines A- D and related dehydrogenated naphthylisoquinoline alkaloids with antiproliferative activities against leukemia cells, from the West African liana Ancistrocladus abbreviatus
-
Cytotoxicity of 40 Egyptian plant extracts targeting mechanisms of drug-resistant cancer cells
-
Collateral Sensitivity of Parthenolide via NF-κB and HIF-α Inhibition and Epigenetic Changes in Drug-Resistant Cancer Cell Lines
-
Optimization of fermentation parameters with magnetically immobilized Bacillus natto on Ginkgo seeds and evaluation of bioactivity and safety
-
The Combined Effects of Ethylene and MeJA on Metabolic Profiling of Phenolic Compounds in Catharanthus roseus Revealed by Metabolomics Analysis
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Evaluating ancient Egyptian prescriptions today : anti-inflammatory activity of Ziziphus spina-christi
-
Best practice in research - Overcoming common challenges in phytopharmacological research
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MicroRNA targeting by quercetin in cancer treatment and chemoprotection
-
MCC1019, a selective inhibitor of the Polo-box domain of Polo-like kinase 1 as novel, potent anticancer candidate
-
Pinolenic acid ameliorates oleic acid-induced lipogenesis and oxidative stress via AMPK/SIRT1 signaling pathway in HepG2 cells
-
Shikonin derivatives for cancer prevention and therapy
-
Cancer combination therapies with artemisinin-type drugs
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Integration of phytochemicals and phytotherapy into cancer precision medicine
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Hepatotoxicity by combination treatment of temozolomide, artesunate and Chinese herbs in a glioblastoma multiforme patient: case report review of the literature
-
Theabrownin Inhibits Cell Cycle Progression and Tumor Growth of Lung Carcinoma through c-myc-Related Mechanism
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Dioncophyllines C2, D2, and F and Related Naphthylisoquinoline Alkaloids from the Congolese Liana Ancistrocladus ileboensis with Potent Activities against Plasmodium falciparum and against Multiple Myeloma and Leukemia Cell Lines
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The role of p53 in cancer drug resistance and targeted chemotherapy
-
Network pharmacology of cancer: From understanding of complex interactomes to the design of multi-target specific therapeutics from nature
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Beyond malaria: The inhibition of viruses by artemisinin-type compounds
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Phytochemicals as inhibitors of NF-κB for treatment of Alzheimer's disease
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Mbandakamine-Type Naphthylisoquinoline Dimers and Related Alkaloids from the Central African Liana Ancistrocladus ealaensis with Antiparasitic and Antileukemic Activities
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Molecular Determinants of Sensitivity or Resistance of Cancer Cells Toward Sanguinarine
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In Vitro Study of the Cytotoxic, Cytostatic, and Antigenotoxic Profile of Hemidesmus indicus (L.) R.Br. (Apocynaceae) Crude Drug Extract on T Lymphoblastic Cells
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Medicinal Plants from Near East for Cancer Therapy
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Pharmacological and chemical features of Nepeta L. genus: Its importance as a therapeutic agent
-
Ancistrolikokine I and further 5,8′-coupled naphthylisoquinoline alkaloids from the Congolese liana Ancistrocladus likoko and their cytotoxic activities against drug-sensitive and multidrug resistant human leukemia cells
-
The activity of Artemisia spp. and their constituents against Trypanosomiasis
-
Theabrownin triggers DNA damage to suppress human osteosarcoma U2OS cells by activating p53 signalling pathway
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Prevention from radiation damage by natural products
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Inhibition of human monoamine oxidase A and B by flavonoids isolated from two Algerian medicinal plants
-
From ancient herb to modern drug: Artemisia annua and artemisinin for cancer therapy
-
Genetic Mouse Models with Intestinal-Specific Tight Junction Deletion Resemble an Ulcerative Colitis Phenotype
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Review of current and "omics" methods for assessing the toxicity (genotoxicity, teratogenicity and nephrotoxicity) of herbal medicines and mushrooms
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Shikonin Directly Targets Mitochondria and Causes Mitochondrial Dysfunction in Cancer Cells
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Cameroonian medicinal plants: pharmacology and derived natural products
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Efficient extraction and preparative separation of four main isoflavonoids from Dalbergia odorifera T. Chen leaves by deep eutectic solvents-based negative pressure cavitation extraction followed by macroporous resin column chromatography
-
Cytotoxicity of methanol extracts of Annona muricata, Passiflora edulis and nine other Cameroonian medicinal plants towards multi-factorial drug-resistant cancer cell lines
-
Antischistosomal activity of artemisinin derivatives in vivo and in patients
-
Immunogenicity of mammary tumor cells can be induced by shikonin via direct binding-interference with hnRNPA1
-
Cytotoxicity of South-African medicinal plants towards sensitive and multidrug-resistant cancer cells
-
Molecular mechanisms of rosmarinic acid from Salvia miltiorrhiza in acute lymphoblastic leukemia cells
-
GPR84 and TREM-1 Signaling Contribute to the Pathogenesis of Reflux Esophagitis
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Kaempferol Derivatives as Antiviral Drugs against the 3a Channel Protein of Coronavirus
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Cytotoxicity, mode of action and antibacterial activities of selected Saudi Arabian medicinal plants
-
A radiosensitizing effect of artesunate in glioblastoma cells is associated with a diminished expression of the inhibitor of apoptosis protein survivin
-
Traditional Chinese medicine research in the post-genomic era: Good practice, priorities, challenges and opportunities
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Characterization of Five Fungal Endophytes Producing Cajaninstilbene Acid Isolated from Pigeon Pea [Cajanus cajan (L.) Millsp.]
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Nobel Prize for artemisinin brings phytotherapy into the spotlight
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Cytotoxicity of three naturally occurring flavonoid derived compounds (artocarpesin, cycloartocarpesin and isobavachalcone) towards multi-factorial drug-resistant cancer cells
-
A Randomised, Double Blind, Placebo-Controlled Pilot Study of Oral Artesunate Therapy for Colorectal Cancer
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Toxicities by Herbal Medicines with Emphasis to Traditional Chinese Medicine
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Chemical Composition and Antiproliferative Activity of Essential Oil from the Leaves of a Medicinal Herb, Levisticum officinale, against UMSCC1 Head and Neck Squamous Carcinoma Cells
-
Cytotoxicity of Thymus vulgaris Essential Oil Towards Human Oral Cavity Squamous Cell Carcinoma
-
Complex Interactions between Phytochemicals. The Multi-Target Therapeutic Concept of Phytotherapy
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Anti-Infectious Bronchitis Virus (IBV) Activity of 1,8-cineole: Effect on Nucleocapsid (N) Protein
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Identification of cellular and molecular factors determining the response of cancer cells to six ergot alkaloids
-
Mechanism of action of Rhodiola, salidroside, tyrosol and triandrin in isolated neuroglial cells: An interactive pathway analysis of the downstream effects using RNA microarray data
-
Coptis chinensis Franch. exhibits neuroprotective properties against oxidative stress in human neuroblastoma cells
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Synergy and antagonism of active constituents of ADAPT-232 on transcriptional level of metabolic regulation of isolated neuroglial cells
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Determination of paclitaxel and other six taxoids in Taxus species by high-performance liquid chromatography-tandem mass spectrometry
-
Molecular determinants of cancer cell sensitivity and resistance towards the sesquiterpene farnesol
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Mechanistic perspectives for 1,2,4-trioxanes in anti-cancer therapy
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Microarray-based detection of multidrug resistance in human tumor cells by expression profiling of ATP-binding cassette transporter genes
-
Molecular modes of action of artesunate in tumor cell lines
-
Mechanisms of Herb-Induced Nephrotoxicity
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IMMUNOHISTOCHEMICAL DETECTION OF THE MULTI-DRUG-RESISTANCE MARKER P-GLYCOPROTEIN IN UTERINE CERVICAL CARCINOMAS AND NORMAL CERVICAL TISSUE
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Trypanosomatid Parasites Causing Neglected Diseases
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The role of copper in drug-resistant murine and human tumors
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Inhibition of angiogenesis in vivo and growth of Kaposi's sarcoma xenograft tumors by the anti-malarial artesunate
-
COX2-Inhibitory and Cytotoxic Activities of Phytoconstituents of Matricaria chamomilla L.
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Two palladium (II) complexes derived from halogen-substituted Schiff bases and 2-picolylamine induce parthanatos-type cell death in sensitive and multi-drug resistant CCRF-CEM leukemia cells
-
Jozimine A2, a Dimeric Naphthylisoquinoline (NIQ) Alkaloid, Shows In Vitro Cytotoxic Effects against Leukemia Cells through NF-κB Inhibition
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Natural products in drug discovery: Advances and opportunities
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Ruthenium(ii) and palladium(ii) homo- and heterobimetallic complexes: synthesis, crystal structures, theoretical calculations and biological studies
-
The endoperoxide ascaridol shows strong differential cytotoxicity in nucleotide excision repair-deficient cells
-
Cajanin stilbene acid: A direct inhibitor of colistin resistance protein MCR-1 that restores the efficacy of polymyxin B against resistant Gram-negative bacteria
-
Carotenoids for lung cancer chemoprevention and chemotherapy: Promises and controversies
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Cynaropicrin disrupts tubulin and c-Myc-related signaling and induces parthanatos-type cell death in multiple myeloma
-
The cardiac glycoside ZINC253504760 induces parthanatos-type cell death and G2/M arrest via downregulation of MEK1/2 phosphorylation in leukemia cells
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Botanical hybrid preparations (BHP) in phytomedicine and phytotherapy research: background and perspectives
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Molecular networking-guided investigation of the secondary metabolome of four Morus species and their in vivo neuroprotective potential for the mitigation of Alzheimer's disease
-
Advances in antitumor activity and mechanism of natural steroidal saponins: A review of advances, challenges, and future prospects
-
Lignan contents of Schisandra chinensis (Turcz.) Baill. from different origins—A new model for evaluating the content of prominent components of Chinese herbs
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Paeonia lactiflora Pall. ameliorates acetaminophen-induced oxidative stress and apoptosis via inhibiting the PKC-ERK pathway
-
Optimized therapeutic potential of Yinchenhao decoction for cholestatic hepatitis by combined network meta-analysis and network pharmacology
-
Molecular insights into experimental models and therapeutics for cholestasis
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State-of-the-Art Review on Botanical Hybrid Preparations in Phytomedicine and Phytotherapy Research: Background and Perspectives
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Investigation of the influence of chirality and halogen atoms on the anticancer activity of enantiopure palladium(II) complexes derived from chiral amino-alcohol Schiff bases and 2-picolylamine
-
Biopiracy versus One-World Medicine-From colonial relicts to global collaborative concepts
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Broken heart, tako-tsubo or stress cardiomyopathy? Metaphors, meanings and their medical impact
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Pharmaceutical care as narrative practice? Rethinking patient-centered care through a pharmacist's perspective
-
Biopiracy of natural products and good bioprospecting practice
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Impact of plastic-related compounds on the gene expression signature of HepG2 cells transfected with CYP3A4
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Identification of Antagonistic Action of Pyrrolizidine Alkaloids in Muscarinic Acetylcholine Receptor M1 by Computational Target Prediction Analysis
-
Obituary: Phytomedicine's Associate Editor Professor Dr. David Yue-Wei Lee has passed away
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Transport processes of radiopharmaceuticals and -modulators
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Gems from traditional north-African medicine : medicinal and aromatic plants from Sudan
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Synergistic inhibition of angiogenesis by artesunate and captopril in vitro and in vivo
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Targeting angiogenesis by phytochemicals
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Cytotoxicity and modes of action of the methanol extracts of six Cameroonian medicinal plants against multidrug-resistant tumor cells
-
Identification of Novel Rare ABCC1 Transporter Mutations in Tumor Biopsies of Cancer Patients
-
Chemometric and Transcriptomic Profiling, Microtubule Disruption and Cell Death Induction by Secalonic Acid in Tumor Cells
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Cytotoxicity and modes of action of four naturally occuring Benzophenones : 2,2',5,6'-tetrahydroxybenzophenone, guttiferone E, isogarcinol and isoxanthochymol
-
Chemopreventive Property of Sencha Tea Extracts towards Sensitive and Multidrug-Resistant Leukemia and Multiple Myeloma Cells
-
Novel artemisinin derivative FO8643 with anti-angiogenic activity inhibits growth and migration of cancer cells via VEGFR2 signaling
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Artemisinin derivative FO-ARS-123 as a novel VEGFR2 inhibitor suppresses angiogenesis, cell migration, and invasion
-
Cytotoxicity, anti-angiogenic, apoptotic effects and transcript profiling of a naturally occurring naphthyl butenone, Guieranone A
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Potential Coronaviral Inhibitors of the Nucleocapsid Protein Identified In Silico and In Vitro from a Large Natural Product Library
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Molecular biology of cantharidin in cancer cells
-
Development of resistance towards artesunate in mda-mb-231 human breast cancer cells
-
Cytotoxicity of endoperoxides from the Caribbean sponge Plakortis halichondrioides towards sensitive and multidrug-resistant leukemia cells : acids vs. esters activity evaluation
-
Interaction of antihistaminic drugs with human translationally controlled tumor protein (TCTP) as novel approach for differentiation therapy
-
Coronavirus Inhibitors Targeting nsp16
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Prediction of cancer drug resistance and implications for personalized medicine
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A drug repurposing approach for individualized cancer therapy based on transcriptome sequencing and virtual drug screening
-
Cytotoxicity of the sesquiterpene lactones neoambrosin and damsin from ambrosia maritima against multidrug-resistant cancer cells
-
Inhibition of c-MYC with involvement of ERK/JNK/MAPK and AKT pathways as a novel mechanism for shikonin and its derivatives in killing leukemia cells
-
Xylochemical Synthesis and Biological Evaluation of Shancigusin C and Bletistrin G
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Elatumic acid : a new ursolic acid congener from omphalocarpum elatum miers (sapotaceae)
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The Chinese herbal formula Free and Easy Wanderer ameliorates oxidative stress through KEAP1-NRF2/HO-1 pathway
-
Synthesis and biological evaluation of a D-ring-contracted analogue of lamellarin D
-
The intestinal 3M (microbiota, metabolism, metabolome) zeitgeist-from fundamentals to future challenges
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Phytomedicine mourns the death of its founding editor Professor Hildebert Wagner
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Nanoscale delivery of phytochemicals targeting CRISPR/Cas9 for cancer therapy
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Cardioprotective effects of phytopigments via multiple signaling pathways
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Network Pharmacology of Ginseng (Part II): The Differential Effects of Red Ginseng and Ginsenoside Rg5 in Cancer and Heart Diseases as Determined by Transcriptomics
-
Synthesis and Cytotoxicity of Diarylpentanoids against Sensitive CCRF-CEM and Multidrug-Resistant CEM/ADR5000 Leukemia Cells
-
Network Pharmacology of Red Ginseng (Part I): Effects of Ginsenoside Rg5 at Physiological and Sub-Physiological Concentrations
-
Epigenetic Alterations Upstream and Downstream of p53 Signaling in Colorectal Carcinoma
-
Differential interactions of the broad spectrum drugs artemisinin, dihydroartemisinin and artesunate with serum albumin
-
Kinome-Wide Profiling Identifies Human WNK3 as a Target of Cajanin Stilbene Acid from Cajanus cajan (L.) Millsp.
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Dietary polyphenols in chemoprevention and synergistic effect in cancer: Clinical evidences and molecular mechanisms of action
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Network Pharmacology of Ginseng (Part II): The Differential Effects of Red Ginseng and Ginsenoside Rg5 in Cancer and Heart Diseases as Determined by Transcriptomics
-
Identification of Novel Anthracycline Resistance Genes and Their Inhibitors
-
Fungal Biofilms as a Valuable Target for the Discovery of Natural Products That Cope with the Resistance of Medically Important Fungi-Latest Findings
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Green tea-derived theabrownin induces cellular senescence and apoptosis of hepatocellular carcinoma through p53 signaling activation and bypassed JNK signaling suppression
-
The neuroprotective potential of carotenoids in vitro and in vivo
-
Ethnopharmacology, phytochemistry, chemical ecology and invasion biology of Acanthus mollis L.
-
Repurposing of the ALK Inhibitor Crizotinib for Acute Leukemia and Multiple Myeloma Cells
-
Identification and characterization of deschloro-chlorothricin obtained from a large natural product library targeting aurora A kinase in multiple myeloma (vol 39, pg 348, 2021)
-
Selection of safe artemisinin derivatives using a machine learning-based cardiotoxicity platform and in vitro and in vivo validation
-
Network pharmacology of triptolide in cancer cells: implications for transcription factor binding
-
A novel ligand of the translationally controlled tumor protein (TCTP) identified by virtual drug screening for cancer differentiation therapy
-
Identification of potential novel drug resistance mechanisms by genomic and transcriptomic profiling of colon cancer cells with p53 deletion
-
Identification and characterization of deschloro-chlorothricin obtained from a large natural product library targeting aurora A kinase in multiple myeloma
-
Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress- and aging-related diseases
-
Identification of inhibitors of the polo-box domain of polo-like kinase 1 from natural and semisynthetic compounds
-
Cytotoxicity of Crude Extract and Isolated Constituents of the Dichrostachys cinerea Bark towards Multifactorial Drug-Resistant Cancer Cells
-
Activity of Cordycepin From Cordyceps sinensis Against Drug-Resistant Tumor Cells as Determined by Gene Expression and Drug Sensitivity Profiling
-
Green Tea-Derived Theabrownin Induces Cellular Senescence and Apoptosis of Hepatocellular Carcinoma via P53 Signaling-Mediated Mechanism Bypassed by JNK Regulation
-
Network Pharmacology of Red Ginseng (Part I): Effects of Ginsenoside Rg5 at Physiological and Sub-Physiological Concentrations
-
Suppression of colorectal carcinogenesis by naringin
-
Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p
-
Cytotoxicity of 4-hydroxy-N-(naphthalen-1-yl)-2-oxo-2H-chromene-3-car-boxamide in multidrug-resistant cancer cells through activation of PERK/eIF2α/ATF4 pathway
-
A novel moniliformin derivative as pan-inhibitor of histone deacetylases triggering apoptosis of leukemia cells
-
Repurposing of artemisinin-type drugs for the treatment of acute leukemia
-
Cytotoxicity and antimitotic activity of Rhinella schneideri and Rhinella marina venoms
-
Cytotoxicity of Salvia miltiorrhiza Against Multidrug-Resistant Cancer Cells
-
Extract of Caragana sinica as a potential therapeutic option for increasing alpha-secretase gene expression
-
Effect of Extraction Methodology on the Phytochemical Composition for Camelia sinensis "Powdered Tea Extracts" from Different Provenances
-
Identification of Phlogacantholide C as a Novel ADAM10 Enhancer from Traditional Chinese Medicinal Plants