Toxicities by Herbal Medicines with Emphasis to Traditional Chinese Medicine

Publikationstyp:
Zeitschriftenaufsatz
Metadaten:
Autoren
  • Thomas Efferth
  • Bernd Kaina
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000299671900009&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.2174/138920011798062328
eISSN
1875-5453
Externe Identifier
  • Clarivate Analytics Document Solution ID: 883YR
  • PubMed Identifier: 21892916
ISSN
1389-2002
Ausgabe der Veröffentlichung
10
Zeitschrift
CURRENT DRUG METABOLISM
Schlüsselwörter
  • Toxicology
  • traditional Chinese medicine
  • medicinal plants
  • herbal medicine
  • phytotherapy
  • pharmacognosy
Paginierung
989 - 996
Datum der Veröffentlichung
2011
Status
Published
Titel
Toxicities by Herbal Medicines with Emphasis to Traditional Chinese Medicine
Sub types
  • Review
Ausgabe der Zeitschrift
12

Datenquelle: Web of Science (Lite)

Andere Metadatenquellen:
Autoren
  • Thomas Efferth
  • Bernd Kaina
DOI
10.2174/138920011798062328
ISSN
1389-2002
Ausgabe der Veröffentlichung
10
Zeitschrift
Current Drug Metabolism
Sprache
en
Paginierung
989 - 996
Datum der Veröffentlichung
2011
Status
Published
Herausgeber
Bentham Science Publishers Ltd.
Herausgeber URL
http://dx.doi.org/10.2174/138920011798062328
Datum der Datenerfassung
2015
Titel
Toxicities by Herbal Medicines with Emphasis to Traditional Chinese Medicine
Ausgabe der Zeitschrift
12

Datenquelle: Crossref

Abstract
It is estimated that three quarters of the world population rely on herbal and traditional medicine as a basis for primary health care. Therefore, it is one of the most important and challenging tasks for scientists working in drug research to investigate the efficacy of herbal medicine, to dissect favorable from adverse effects, to identify active principles in medicinal plants and to ban poisonous plants or contaminations from herbal mixtures. In the present review, some problems are critically discussed. Botanical misidentification or mislabeling of plant material can play a role for toxic reactions in humans. Some plant descriptions in traditional herbal medicine (e.g. traditional Chinese medicine) have changed over time, which may lead to unintended intoxication by using wrong plants. A problem is also the contamination of herbals with microorganisms, fungal toxins such as aflatoxin, with pesticides and heavy metals. Unprofessional processing, which differs from safe traditional preparation represents another potential source for herbal poisoning. Unwanted effects of herbal products may also develop by the interaction of herbs with conventional drugs upon concomitant intake. The art of herbal medicine is to dissect pharmacologically and therapeutically valuable herbal drugs from harmful and toxic ones and to develop combinations of medicinal plants as safe and efficient herbal remedies. Standardization and strict control measures are necessary to monitor sustainable high quality of herbal products and to exclude contaminations that badly affect patients consuming herbal medicine.
Addresses
  • Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemistry, University of Mainz, Staudinger Weg 5, 55128 Mainz, Germany. efferth@uni-mainz.de
Autoren
DOI
10.2174/138920011798062328
eISSN
1875-5453
Externe Identifier
  • PubMed Identifier: 21892916
Open access
false
ISSN
1389-2002
Ausgabe der Veröffentlichung
10
Zeitschrift
Current drug metabolism
Schlüsselwörter
  • Plants, Medicinal
  • Drugs, Chinese Herbal
  • Medicine, Chinese Traditional
  • Phytotherapy
  • Drug Contamination
  • Herb-Drug Interactions
  • Herbal Medicine
Sprache
eng
Medium
Print
Paginierung
989 - 996
Datum der Veröffentlichung
2011
Status
Published
Datum der Datenerfassung
2011
Titel
Toxicities by herbal medicines with emphasis to traditional Chinese medicine.
Sub types
  • Review
  • Journal Article
Ausgabe der Zeitschrift
12

Datenquelle: Europe PubMed Central

Abstract
It is estimated that three quarters of the world population rely on herbal and traditional medicine as a basis for primary health care. Therefore, it is one of the most important and challenging tasks for scientists working in drug research to investigate the efficacy of herbal medicine, to dissect favorable from adverse effects, to identify active principles in medicinal plants and to ban poisonous plants or contaminations from herbal mixtures. In the present review, some problems are critically discussed. Botanical misidentification or mislabeling of plant material can play a role for toxic reactions in humans. Some plant descriptions in traditional herbal medicine (e.g. traditional Chinese medicine) have changed over time, which may lead to unintended intoxication by using wrong plants. A problem is also the contamination of herbals with microorganisms, fungal toxins such as aflatoxin, with pesticides and heavy metals. Unprofessional processing, which differs from safe traditional preparation represents another potential source for herbal poisoning. Unwanted effects of herbal products may also develop by the interaction of herbs with conventional drugs upon concomitant intake. The art of herbal medicine is to dissect pharmacologically and therapeutically valuable herbal drugs from harmful and toxic ones and to develop combinations of medicinal plants as safe and efficient herbal remedies. Standardization and strict control measures are necessary to monitor sustainable high quality of herbal products and to exclude contaminations that badly affect patients consuming herbal medicine.
Date of acceptance
2011
Autoren
  • Thomas Efferth
  • Bernd Kaina
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/21892916
DOI
10.2174/138920011798062328
eISSN
1875-5453
Ausgabe der Veröffentlichung
10
Zeitschrift
Curr Drug Metab
Schlüsselwörter
  • Drug Contamination
  • Drugs, Chinese Herbal
  • Herb-Drug Interactions
  • Herbal Medicine
  • Medicine, Chinese Traditional
  • Phytotherapy
  • Plants, Medicinal
Sprache
eng
Country
Netherlands
Paginierung
989 - 996
PII
BSP/CDM/E-Pub/000207
Datum der Veröffentlichung
2011
Status
Published
Datum, an dem der Datensatz öffentlich gemacht wurde
2012
Titel
Toxicities by herbal medicines with emphasis to traditional Chinese medicine.
Sub types
  • Journal Article
  • Review
Ausgabe der Zeitschrift
12

Datenquelle: PubMed

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