Elatumic Acid: A New Ursolic Acid Congener from Omphalocarpum elatum Miers (Sapotaceae)

Publikationstyp:
Zeitschriftenaufsatz
Metadaten:
Autoren
  • Louis P Sandjo
  • Chi G Fru
  • Victor Kuete
  • Frederic Nana
  • Samuel O Yeboah
  • Renameditswe Mapitse
  • Berhanu M Abegaz
  • Thomas Efferth
  • Till Opatz
  • Bonaventure T Ngadjui
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000343191800002&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.5560/ZNC.2014-0050
eISSN
1865-7125
Externe Identifier
  • Clarivate Analytics Document Solution ID: AQ9RA
  • PubMed Identifier: 25265847
ISSN
0939-5075
Ausgabe der Veröffentlichung
7-8
Zeitschrift
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES
Schlüsselwörter
  • Omphalocarpum elatum
  • Triterpene
  • Cytotoxicity
  • Antimicrobial
Paginierung
276 - 282
Datum der Veröffentlichung
2014
Status
Published
Titel
Elatumic Acid: A New Ursolic Acid Congener from <i>Omphalocarpum elatum</i> Miers (Sapotaceae)
Sub types
  • Article
Ausgabe der Zeitschrift
69

Datenquelle: Web of Science (Lite)

Andere Metadatenquellen:
Abstract
<jats:p>A new triterpene diastereomer, 1, of the previously reported 3β,6β,19α-trihydroxy-urs-12-en- 28-oic acid-24-carboxylic acid methyl ester was obtained from the stem bark of Omphalocarpum elatum Miers (Sapotaceae) along with α-amyrin acetate (2), spinasterol (3), spinasterol 3-O-β-Dglucopyranoside (4), and tormentic acid (5). The structures of the isolates were established on the basis of NMR and mass spectrometric data and by comparison with those previously reported in the literature. Compound 1 showed weak antibacterial activity against E. aerogenes ATCC13048 and EA3, K. pneumoniae ATCC29916, and P. aeruginosa; it also displayed moderate cytotoxicity against CCRF-CEM, CEM=ADR5000, and MDA-MB231 cells. </jats:p>
Autoren
  • Louis P Sandjo
  • Chi G Fru
  • Victor Kuete
  • Frederic Nana
  • Samuel O Yeboah
  • Renameditswe Mapitse
  • Berhanu M Abegaz
  • Thomas Efferth
  • Till Opatz
  • Bonaventure T Ngadjui
DOI
10.5560/znc.2014-0050
eISSN
1865-7125
ISSN
0939-5075
Ausgabe der Veröffentlichung
7-8
Zeitschrift
Zeitschrift für Naturforschung C
Sprache
en
Online publication date
2014
Paginierung
276 - 282
Datum der Veröffentlichung
2014
Status
Published
Herausgeber
Walter de Gruyter GmbH
Herausgeber URL
http://dx.doi.org/10.5560/znc.2014-0050
Datum der Datenerfassung
2021
Titel
Elatumic Acid: A New Ursolic Acid Congener from Omphalocarpum elatum Miers (Sapotaceae)
Ausgabe der Zeitschrift
69

Datenquelle: Crossref

Abstract
A new triterpene diastereomer, 1, of the previously reported 3beta,6beta,19alpha-trihydroxy-urs-12-en-28-oic acid-24-carboxylic acid methyl ester was obtained from the stem bark of Omphalocarpum elatum Miers (Sapotaceae) along with a-amyrin acetate (2), spinasterol (3), spinasterol 3-O-beta-D-glucopyranoside (4), and tormentic acid (5). The structures of the isolates were established on the basis of NMR and mass spectrometric data and by comparison with those previously reported in the literature. Compound 1 showed weak antibacterial activity against E. aerogenes ATCC13048 and EA3, K. pneumoniae ATCC29916, and P aeruginosa; it also displayed moderate cytotoxicity against CCRF-CEM, CEM/ADR5000, and MDA-MB231 cells.
Autoren
  • Louis P Sandjo
  • Chi G Fru
  • Victor Kuete
  • Frederic Nana
  • Samuel O Yeboah
  • Renameditswe Mapitse
  • Berhanu M Abegaz
  • Thomas Efferth
  • Thomas Efferth
  • Till Opatz
  • Bonaventure T Ngadjui
DOI
10.5560/znc.2014-0050
eISSN
1865-7125
Externe Identifier
  • PubMed Identifier: 25265847
Open access
false
ISSN
0939-5075
Ausgabe der Veröffentlichung
7-8
Zeitschrift
Zeitschrift fur Naturforschung. C, Journal of biosciences
Schlüsselwörter
  • Cell Line, Tumor
  • Humans
  • Sapotaceae
  • Triterpenes
  • Anti-Bacterial Agents
  • Magnetic Resonance Spectroscopy
  • Spectrometry, Mass, Electrospray Ionization
  • Drug Screening Assays, Antitumor
  • Microbial Sensitivity Tests
  • Molecular Structure
Sprache
eng
Medium
Print
Paginierung
276 - 282
Datum der Veröffentlichung
2014
Status
Published
Datum der Datenerfassung
2014
Titel
Elatumic acid: a new ursolic acid congener from Omphalocarpum elatum Miers (Sapotaceae).
Sub types
  • Research Support, Non-U.S. Gov't
  • Journal Article
Ausgabe der Zeitschrift
69

Datenquelle: Europe PubMed Central

Abstract
A new triterpene diastereomer, 1, of the previously reported 3beta,6beta,19alpha-trihydroxy-urs-12-en-28-oic acid-24-carboxylic acid methyl ester was obtained from the stem bark of Omphalocarpum elatum Miers (Sapotaceae) along with a-amyrin acetate (2), spinasterol (3), spinasterol 3-O-beta-D-glucopyranoside (4), and tormentic acid (5). The structures of the isolates were established on the basis of NMR and mass spectrometric data and by comparison with those previously reported in the literature. Compound 1 showed weak antibacterial activity against E. aerogenes ATCC13048 and EA3, K. pneumoniae ATCC29916, and P aeruginosa; it also displayed moderate cytotoxicity against CCRF-CEM, CEM/ADR5000, and MDA-MB231 cells.
Autoren
  • Louis P Sandjo
  • Chi G Fru
  • Victor Kuete
  • Frederic Nana
  • Samuel O Yeboah
  • Renameditswe Mapitse
  • Berhanu M Abegaz
  • Thomas Efferth
  • Till Opatz
  • Bonaventure T Ngadjui
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/25265847
DOI
10.5560/znc.2014-0050
ISSN
0939-5075
Ausgabe der Veröffentlichung
7-8
Zeitschrift
Z Naturforsch C J Biosci
Schlüsselwörter
  • Anti-Bacterial Agents
  • Cell Line, Tumor
  • Drug Screening Assays, Antitumor
  • Humans
  • Magnetic Resonance Spectroscopy
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Sapotaceae
  • Spectrometry, Mass, Electrospray Ionization
  • Triterpenes
Sprache
eng
Country
Germany
Paginierung
276 - 282
Datum der Veröffentlichung
2014
Status
Published
Datum, an dem der Datensatz öffentlich gemacht wurde
2014
Titel
Elatumic acid: a new ursolic acid congener from Omphalocarpum elatum Miers (Sapotaceae).
Sub types
  • Journal Article
  • Research Support, Non-U.S. Gov't
Ausgabe der Zeitschrift
69

Datenquelle: PubMed

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