Phytochemical and pharmacological properties of essential oils from Cedrus species
- Publikationstyp:
- Zeitschriftenaufsatz
- Metadaten:
-
- Autoren
- Antoine M Saab
- Roberto Gambari
- Gianni Sacchetti
- Alessandra Guerrini
- Ilaria Lampronti
- Massimo Tacchini
- Antoine El Samrani
- Samir Medawar
- Hassane Makhlouf
- Mona Tannoury
- Jihad Abboud
- Mona Diab-Assaf
- Anake Kijjoa
- Rosa Tundis
- Jawad Aoun
- Thomas Efferth
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000430863800008&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1080/14786419.2017.1346648
- eISSN
- 1478-6427
- Externe Identifier
- Clarivate Analytics Document Solution ID: GD9WN
- PubMed Identifier: 28670915
- ISSN
- 1478-6419
- Ausgabe der Veröffentlichung
- 12
- Zeitschrift
- NATURAL PRODUCT RESEARCH
- Schlüsselwörter
- Antiproliferative activity
- leukaemia cells
- essential oils
- Cedrus libani
- Cedrus atlantica
- Cedrus deodara
- Pinaceae
- Paginierung
- 1415 - 1427
- Datum der Veröffentlichung
- 2018
- Status
- Published
- Titel
- Phytochemical and pharmacological properties of essential oils from <i>Cedrus</i> species
- Sub types
- Review
- Ausgabe der Zeitschrift
- 32
Datenquelle: Web of Science (Lite)
- Andere Metadatenquellen:
-
- Autoren
- Antoine M Saab
- Roberto Gambari
- Gianni Sacchetti
- Alessandra Guerrini
- Ilaria Lampronti
- Massimo Tacchini
- Antoine El Samrani
- Samir Medawar
- Hassane Makhlouf
- Mona Tannoury
- Jihad Abboud
- Mona Diab-Assaf
- Anake Kijjoa
- Rosa Tundis
- Jawad Aoun
- Thomas Efferth
- DOI
- 10.1080/14786419.2017.1346648
- eISSN
- 1478-6427
- ISSN
- 1478-6419
- Ausgabe der Veröffentlichung
- 12
- Zeitschrift
- Natural Product Research
- Sprache
- en
- Online publication date
- 2017
- Paginierung
- 1415 - 1427
- Datum der Veröffentlichung
- 2018
- Status
- Published
- Herausgeber
- Informa UK Limited
- Herausgeber URL
- http://dx.doi.org/10.1080/14786419.2017.1346648
- Datum der Datenerfassung
- 2020
- Titel
- Phytochemical and pharmacological properties of essential oils from <i>Cedrus</i> species
- Ausgabe der Zeitschrift
- 32
Datenquelle: Crossref
- Abstract
- Natural products frequently exert pharmacological activities. The present review gives an overview of the ethnobotany, phytochemistry and pharmacology of the Cedrus genus, e.g. cytotoxic, spasmolytic immunomodulatory, antiallergic, anti-inflammatory and analgesic activities. Cancer patients frequently seek remedies from traditional medicinal plants that are believed to exert less side effects than conventional therapy with synthetic drugs. A long-lasting goal of anti-cancer and anti-microbial therapy research is to find compounds with reduced side effects compared to currently approved drugs. In this respect, Cedrus species might be of interest. The essential oil isolated from Cedrus libani leaves may bear potential for drug development due to its high concentrations of germacrene D and β-caryophyllene. The essential oils from Cedrus species also show bioactivity against bacteria and viruses. More preclinical analyses (e.g. in vivo experiments) as well as clinical trials are required to evaluate the potential of essential oils from Cedrus species for drug development.
- Addresses
- a Faculty of Science II, Department of Biochemistry and Chemistry , Lebanese University , Lebanon.
- Autoren
- Antoine M Saab
- Roberto Gambari
- Gianni Sacchetti
- Alessandra Guerrini
- Ilaria Lampronti
- Massimo Tacchini
- Antoine El Samrani
- Samir Medawar
- Hassane Makhlouf
- Mona Tannoury
- Jihad Abboud
- Mona Diab-Assaf
- Anake Kijjoa
- Rosa Tundis
- Jawad Aoun
- Thomas Efferth
- Thomas Efferth
- DOI
- 10.1080/14786419.2017.1346648
- eISSN
- 1478-6427
- Externe Identifier
- PubMed Identifier: 28670915
- Open access
- false
- ISSN
- 1478-6419
- Ausgabe der Veröffentlichung
- 12
- Zeitschrift
- Natural product research
- Schlüsselwörter
- Humans
- Cedrus
- Plant Leaves
- Plants, Medicinal
- Sesquiterpenes
- Oils, Volatile
- Anti-Inflammatory Agents
- Antineoplastic Agents, Phytogenic
- Anti-Infective Agents
- Phytochemicals
- Polycyclic Sesquiterpenes
- Sprache
- eng
- Medium
- Print-Electronic
- Online publication date
- 2017
- Paginierung
- 1415 - 1427
- Datum der Veröffentlichung
- 2018
- Status
- Published
- Datum der Datenerfassung
- 2017
- Titel
- Phytochemical and pharmacological properties of essential oils from Cedrus species.
- Sub types
- Review
- Journal Article
- Ausgabe der Zeitschrift
- 32
Datenquelle: Europe PubMed Central
- Abstract
- Natural products frequently exert pharmacological activities. The present review gives an overview of the ethnobotany, phytochemistry and pharmacology of the Cedrus genus, e.g. cytotoxic, spasmolytic immunomodulatory, antiallergic, anti-inflammatory and analgesic activities. Cancer patients frequently seek remedies from traditional medicinal plants that are believed to exert less side effects than conventional therapy with synthetic drugs. A long-lasting goal of anti-cancer and anti-microbial therapy research is to find compounds with reduced side effects compared to currently approved drugs. In this respect, Cedrus species might be of interest. The essential oil isolated from Cedrus libani leaves may bear potential for drug development due to its high concentrations of germacrene D and β-caryophyllene. The essential oils from Cedrus species also show bioactivity against bacteria and viruses. More preclinical analyses (e.g. in vivo experiments) as well as clinical trials are required to evaluate the potential of essential oils from Cedrus species for drug development.
- Autoren
- Antoine M Saab
- Roberto Gambari
- Gianni Sacchetti
- Alessandra Guerrini
- Ilaria Lampronti
- Massimo Tacchini
- Antoine El Samrani
- Samir Medawar
- Hassane Makhlouf
- Mona Tannoury
- Jihad Abboud
- Mona Diab-Assaf
- Anake Kijjoa
- Rosa Tundis
- Jawad Aoun
- Thomas Efferth
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/28670915
- DOI
- 10.1080/14786419.2017.1346648
- eISSN
- 1478-6427
- Ausgabe der Veröffentlichung
- 12
- Zeitschrift
- Nat Prod Res
- Schlüsselwörter
- Antiproliferative activity
- Cedrus atlantica
- Cedrus deodara
- Cedrus libani
- Pinaceae
- essential oils
- leukaemia cells
- Anti-Infective Agents
- Anti-Inflammatory Agents
- Antineoplastic Agents, Phytogenic
- Cedrus
- Humans
- Oils, Volatile
- Phytochemicals
- Plant Leaves
- Plants, Medicinal
- Polycyclic Sesquiterpenes
- Sesquiterpenes
- Sprache
- eng
- Country
- England
- Paginierung
- 1415 - 1427
- Datum der Veröffentlichung
- 2018
- Status
- Published
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2018
- Titel
- Phytochemical and pharmacological properties of essential oils from Cedrus species.
- Sub types
- Journal Article
- Review
- Ausgabe der Zeitschrift
- 32
Datenquelle: PubMed
- Beziehungen:
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