Pharmazeutische Biologie
- Beziehungen:
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- Artemisian-Type Compounds: From Traditional Chinese Medicine to Novel Drugs
- From Molecular Tumor Diagnostics to Individualized Treatment with Phytochemicals Derived from Chinese Herbs
- Animal plant warfare and secondary metabolite evolution
- Diversity of pharmacological properties in Chinese and European medicinal plants: Cytotoxicity, antiviral and antitrypanosomal screening of 82 herbal drugs
- Drug Repurposing in Cancer Therapy
- Prevention of plant crown gall tumor development by the anti-malarial artesunate of Artemisia annua
- Molecular determinants of response of tumor cells to berberine
- Traditional medicine with plants-present and past
- Biotechnology has come of age
- Diagnosis and objective pain assessment of traditional Chinese medicine may be useful to demonstrate specific effects of acupuncture in low back pain: A prospective, randomized, controlled and single blinded pre-study
- Selected secondary plant metabolites for cancer therapy
- Molecular mechanisms and interactions responsible for radio-and chemoresistance of tumors and their modulation by natural products from Ayurveda
- Natural Medicines
- Anti-inflammatory and anti-cancer activity of boswellic acids from frankincense (Boswellia serrata Roxb. et Colebr, B. carterii Birdw.)
- Treatment of Iron-Loaded Veterinary Sarcoma by Artemisia annua
- Adaptogens in chemobrain (Part III): Antitoxic effects of plant extracts towards cancer chemotherapy-induced toxicity - transcriptome-wide microarray analysis of neuroglia cells
- Molecular bases of the poor response of liver cancer to chemotherapy
- Ziziphora tenuior L. essential oil from Dana Biosphere Reserve (Southern Jordan); Chemical characterization and assessment of biological activities
- Cryptotanshinone deregulates unfolded protein response and eukaryotic initiation factor signaling in acute lymphoblastic leukemia cells
- Induction of cholesterol biosynthesis by archazolid B in T24 bladder cancer cells
- Antiangiogenic Activity and Pharmacogenomics of Medicinal Plants from Traditional Korean Medicine
- First Study of Oral Artenimol-R in Advanced Cervical Cancer: Clinical Benefit, Tolerability and Tumor Markers
- Phytomedicine in Otorhinolaryngology and Pulmonology: Clinical Trials with Herbal Remedies
- Natural Products in Structure-Assisted Design of Molecular Cancer Therapeutics
- Effect of artesunate on immune cells in ret-transgenic mouse melanoma model
- EGFR but not PDGFR-β expression correlates to the antiproliferative effect of growth factor withdrawal in glioblastoma multiforme cell lines
- RECIPROCAL CORRELATION BETWEEN EXPRESSION OF P-GLYCOPROTEIN AND ACCUMULATION OF RHODAMINE-123 IN HUMAN TUMORS
- Small Molecules of Natural Origin for Cancer Therapy and Chemoprevention Part II: Pharmacogenomics and biotechnological applications of small molecules of natural origin for cancer therapy and chemoprevention
- Epidermal Growth Factor Receptors and Downstream Signalling Pathways as Cancer Treatment Targets for Medicinal Plants
- MODULATION OF CORTICOTROPIN RELEASING HORMONE SIGNALING IN MOUSE INTESTINAL ORGANOIDS BY STW 5-II: POSSIBLE MECHANISMS FOR THE MANGAEMNT OF DISORDERS OF GUT-BRAIN INTERACTIONS
- Animals and animal toxins in traditional and modern medicine
- Cytotoxicity of main anthraquinone aglycons towards drug sensitive and multi drug resistant T leukaemia cancer cells
- Cytotoxic activity of mammea type coumarins from Mammea siamensis flowers
- Differential expression of the drug resistance markers DNA topoisomerase IIα and glutathion S-transferase-π in the histological compartments of Wilms' tumors (vol 21, pg 771, 2001)
- Cell growth of sunitinib-resistant renal cell carcinoma was inhibited by Shikonin through necroptosis induction and Akt/mTOR signaling inhibition.
- Cell growth of sunitinib-resistant renal cell carcinoma was inhibited by Shikonin through necroptosis induction and Akt/mTOR signaling inhibition
- Editorial: Phytonutrients in the treatment of cancer: Mechanistic insights and therapeutic prospects
- Jozibrevine D from Ancistrocladus ileboensis, the fifth alkaloid in a series of six possible atropo-diastereomeric naphthylisoquinoline dimers, showing antiparasitic and antileukemic activities
- Pomiferin targets SERCA, mTOR, and P-gp to induce autophagic cell death in apoptosis-resistant cancer cells, and reverses the MDR phenotype in cisplatin-resistant tumors in vivo
- Phytochemical profiling of polyphenols and thyroid stimulatory activity of Ficus religiosa leaf extract in 6-propyl-thiouracil-induced hypothyroid rats
- In Silico and In Vitro Identification of P-Glycoprotein Inhibitors from a Library of 375 Phytochemicals
- The Effect of Plastic-Related Compounds on Transcriptome-Wide Gene Expression on CYP2C19-Overexpressing HepG2 Cells
- A critical review of machine-learning for "multi-omics" marine metabolite datasets
- Cytotoxicity, acute and sub-chronic toxicities of the leaves of Bauhinia thonningii (Schumach.) Milne-Redh. (Caesalpiniaceae)
- Anticancer activity of Bacopa monnieri through apoptosis induction and mitophagy-dependent NLRP3 inflammasome inhibition in oral squamous cell carcinoma
- Anti-inflammatory effects of herbal preparation STW5-II in cytokine challenged normal human colon cells
- Drug repurposing using transcriptome sequencing and virtual drug screening in a patient with glioblastoma
- West meets east: open up a dialogue on phytomedicine
- The triterpenoid ursolic acid ameliorates stress in Caenorhabditis elegans by affecting the depression-associated genes skn-1 and prdx2
- Anti-inflammatory and tight junction protective activity of the herbal preparation STW 5-II on mouse intestinal organoids
- Role of Levo-tetrahydropalmatine and its metabolites for management of chronic pain and opioid use disorders
- In Vitro and In Silico Studies of Two 1,4-Naphthoquinones and their Topi- cal Formulation in Bigels
- Botanicals and phytochemicals from the bark of Hypericum roeperianum (Hypericaceae) had strong antibacterial activity and showed synergistic effects with antibiotics against multidrug-resistant bacteria expressing active efflux pumps
- Cytotoxic alkaloids from the root of Zanthoxylum paracanthum (mildbr) Kokwaro
- Identification of novel drug resistance mechanisms by genomic and transcriptomic profiling of glioblastoma cells with mutation-activated EGFR
- Chemoprevention and therapeutic role of essential oils and phenolic compounds: Modeling tumor microenvironment in glioblastoma
- Withanone Ameliorates Stress Symptoms in Caenorhabditis Elegans by Acting through Serotonin Receptors
- Increased Stress Resistance and Lifespan in Chaenorhabditis elegans Wildtype and Knockout Mutants-Implications for Depression Treatment by Medicinal Herbs
- Bioactivity of fractions and constituents of Piper capense fruits towards a broad panel of cancer cells
- Toxicity as prime selection criterion among SARS-active herbal medications
- Induction of stress resistance and extension of lifespan in Chaenorhabditis elegans serotonin-receptor knockout strains by withanolide A
- Artesunate Impairs Growth in Cisplatin-Resistant Bladder Cancer Cells by Cell Cycle Arrest, Apoptosis and Autophagy Induction
- Ursolic acid ameliorates stress and reactive oxygen species in C. elegans knockout mutants by the dopamine Dop1 and Dop3 receptors
- Identification of metastasis-related genes by genomic and transcriptomic studies in murine melanoma
- AMG900 as novel inhibitor of the translationally controlled tumor protein
- Genomic landscape analyses in cervical carcinoma and consequences for treatment
- Exploring natural products-based cancer therapeutics derived from egyptian flora
- Induction of Apoptosis, Autophagy and Ferroptosis by Thymus vulgaris and Arctium lappa Extract in Leukemia and Multiple Myeloma Cell Lines
- Cytotoxicity of botanicals and isolated phytochemicals from Araliopsis soyauxii Engl. (Rutaceae) towards a panel of human cancer cells
- Cytotoxicity and apoptosis induction by Fumaria officinalis extracts in leukemia and multiple myeloma cell lines
- Multiple modes of cell death in neuroendocrine tumors induced by artesunate
- Evaluation of Long-Time Decoction-DetoxicatedHei-Shun-Pian(ProcessedAconitum carmichaeliDebeaux Lateral Root With Peel) for Its Acute Toxicity and Therapeutic Effect on Mono-Iodoacetate Induced Osteoarthritis
- Salvia ceratophyllaL. from South of Jordan: new insights on chemical composition and biological activities
- Steroidal saponins from Raphia vinifera and their cytotoxic activity
- Comprehensive Overview on Multiple Strategies Fighting COVID-19
- Cytotoxic bufadienolides from the leaves of a medicinal plant Melianthus comosus collected in South Africa
- Identification of potential inhibitors targeting BRAF-V600E mutant melanoma cells
- Investigation of cancer drug resistance mechanisms by phosphoproteomics
- Putative molecular determinants mediating sensitivity or resistance towards carnosic acid tumor cell responses
- Cytotoxic Bufadienolides from the Leaves of Melianthus major
- Targeting epigenetics in cancer: therapeutic potential of flavonoids
- N-acetylglycoside of oleanolic acid (aridanin) displays promising cytotoxicity towards human and animal cancer cells, inducing apoptotic, ferroptotic and necroptotic cell death
- Immunotoxicity of Therapeutic Antibodies and Nanoparticles
- Organoids of human airways to study infectivity and cytopathy of SARS-CoV-2
- 8,8-bis-(Dihydroconiferyl)-diferulate displayed impressive cytotoxicity towards a panel of human and animal cancer cells
- Cryptochlorogenic acid attenuates LPS-induced inflammatory response and oxidative stress via upregulation of the Nrf2/HO-1 signaling pathway in RAW 264.7 macrophages
- Indeno[1,2,3-cd]pyrene and picene mediate actions via estrogen receptor α signaling pathway in in vitro cell systems, altering gene expression
- Small molecule inhibitors and stimulators of inducible nitric oxide synthase in cancer cells from natural origin (phytochemicals, marine compounds, antibiotics)
- Retrospective study of small pet tumors treated with Artemisia annua and iron
- The antioxidant 2,3-dichloro,5,8-dihydroxy,1,4-naphthoquinone inhibits acetyl-cholinesterase activity and amyloid β42 aggregation: A dual target therapeutic candidate compound for the treatment of Alzheimer's disease
- Terpenoid bio-transformations and applications via cell/organ cultures: a systematic review
- A Machine Learning-Based Prediction Platform for P-Glycoprotein Modulators and Its Validation by Molecular Docking
- Comparison between tumors in plants and human beings: Mechanisms of tumor development and therapy with secondary plant metabolites
- Combining the wisdoms of traditional medicine with cutting-edge science and technology at the forefront of medical sciences
- Interactions between artemisinin derivatives and P-glycoprotein
- Professor Hildebert Wagner celebrates his 90th birthday
- Broad-spectrum Cross-resistance to Anticancer Drugs Mediated by Epidermal Growth Factor Receptor
- Antiulcer activity of Cyperus alternifolius in relation to its UPLC-MS metabolite fingerprint: A mechanistic study
- Editorial: Chemoprevention of cancer by natural products
- Plants mentioned in the Islamic Scriptures (Holy Qur'an and Ahadith): Traditional uses and medicinal importance in contemporary times
- Ca2+ signalling plays a role in celastrol-mediated suppression of synovial fibroblasts of rheumatoid arthritis patients and experimental arthritis in rats
- Chondroprotective effects of platelet lysate towards monoiodoacetate-induced arthritis by suppression of TNF-α-induced activation of NF-κB pathway in chondrocytes
- Collateral sensitivity of drug-resistant ABCB5-and mutation-activated EGFR overexpressing cells towards resveratrol due to modulation of SIRT1 expression
- Relationship between EGFR expression and subcellular localization with cancer development and clinical outcome
- Adaptogens in chemobrain (Part II): Effect of plant extracts on chemotherapy-induced cytotoxicity in neuroglia cells
- Cytotoxicity of isoflavones and biflavonoids from Ormocarpum kirkii towards multi-factorial drug resistant cancer
- 2′-O-galloylhyperin attenuates LPS-induced acute lung injury via upregulation antioxidation and inhibition of inflammatory responses in vivo
- Adaptogens in chemobrain (Part I): Plant extracts attenuate cancer chemotherapy-induced cognitive impairment - Transcriptome-wide microarray profiles of neuroglia cells
- IN VIVO ACUTE TOXICITY OF DETOXIFIED FUZI (LATERAL ROOT OF ACONITUM CARMICHAELI) AFTER A TRADITIONAL DETOXIFICATION PROCESS
- Cardenolides: Insights from chemical structure and pharmacological utility
- Cell Harvesting Methods Affect Cellular Integrity of Adherent Cells During Apoptosis Detection
- Agkistrodon ameliorates pain response and prevents cartilage degradation in monosodium iodoacetate-induced osteoarthritic rats by inhibiting chondrocyte hypertrophy and apoptosis
- Intra-Articular Injection of Fructus Ligustri Lucidi Extract Attenuates Pain Behavior and Cartilage Degeneration in Mono-Iodoacetate Induced Osteoarthritic Rats
- Cytotoxicity of nimbolide towards multidrug-resistant tumor cells and hypersensitivity via cellular metabolic modulation
- Curcumin downregulates expression of opioid-related nociceptin receptor gene (OPRL1) in isolated neuroglia cells
- Epimagnolin A, a tetrahydrofurofuranoid lignan from Magnolia fargesii, reverses ABCB1-mediated drug resistance
- Diabetes and Metabolism Disorders Medicinal Plants: A Glance at the Past and a Look to the Future 2018
- Biopiracy of medicinal plants: Finding fair solutions for the use of natural resources
- Correction: Immunogenicity of mammary tumor cells can be induced by shikonin via direct binding-interference with hnRNPA1
- Cytotoxicity of epunctanone and four other phytochemicals isolated from the medicinal plants Garcinia epunctata and Ptycholobium contortum towards multi-factorial drug resistant cancer cells
- Total ginsenosides of Chinese ginseng induces cell cycle arrest and apoptosis in colorectal carcinoma HT-29 cells
- Prospecting for cytotoxic and antiprotozoal 4-aryl-4H-chromenes and 10-aryldihydropyrano[2,3-f]chromenes
- Natural Products as a Source for New Leads in Cancer Research and Treatment
- Cytotoxicity of abietane diterpenoids from Salvia multicaulis towards multidrug-resistant cancer cells
- Selective inhibition of P-gp transporter by goniothalamin derivatives sensitizes resistant cancer cells to chemotherapy
- Identification of fatal outcome in a childhood nasopharyngeal carcinoma patient by protein expression profiling
- 2′-O-Galloylhyperin Isolated From Pyrola incarnata Fisch Attenuates LPS-Induced Inflammatory Response by Activation of SIRT1/Nrf2 and Inhibition of the NF-κB Pathways in Vitro and Vivo
- The hydrolysis of 6-phosphogluconolactone in the second step of pentose phosphate pathway occurs via a two-water mechanism
- Synthesis of Novel Hybrids of Quinazoline and Artemisinin with High Activities against Plasmodium falciparum, Human Cytomegalovirus, and Leukemia Cells
- Polyacanthoside A, a new oleanane-type triterpenoid saponin with cytotoxic effects from the leaves of Acacia polyacantha (Fabaceae)
- Antimicrobial and Antioxidant Activities of Natural Compounds
- Prevention of carcinogenesis and metastasis by Artemisinin-type drugs
- Betulinic Acid Exerts Cytotoxic Activity Against Multidrug-Resistant Tumor Cells via Targeting Autocrine Motility Factor Receptor (AMFR)
- Access to new highly potent antileukemia, antiviral and antimalarial agents via hybridization of natural products (homo)egonol, thymoquinone and artemisinin
- Oridonin Targets Multiple Drug-Resistant Tumor Cells as Determined by in Silico and in Vitro Analyses
- Total Synthesis and Biological Investigation of (-)-Artemisinin: The Antimalarial Activity of Artemisinin Is not Stereospecific
- Cytotoxic flavonoids from two Lonchocarpus species
- Insights into apoptotic proteins in chemotherapy: quantification techniques and informing therapy choice
- Aloe-emodin as drug candidate for cancer therapy
- Threats to human health by great ocean garbage patches
- Treatment of Multidrug-Resistant Leukemia Cells by Novel Artemisinin-, Egonol-, and Thymoquinone-Derived Hybrid Compounds
- In Vitro Antioxidant and Cytotoxic Activities of 18 Plants from the Erkowit Region, Eastern Sudan
- Multifactorial Modes of Action of Arsenic Trioxide in Cancer Cells as Analyzed by Classical and Network Pharmacology
- Daphne striata Tratt. and D. mezereum L.: a study of anti-proliferative activity towards human cancer cells and antioxidant properties
- Cytotoxic activity of medicinal plants of the Kakamega County (Kenya) against drug-sensitive and multidrug-resistant cancer cells
- Role of TCTP for Cellular Differentiation and Cancer Therapy
- Cancer combination therapy of the sesquiterpenoid artesunate and the selective EGFR-tyrosine kinase inhibitor erlotinib
- Introduction: Novel hybrid combinations containing synthetic or antibiotic drugs with plant-derived phenolic or terpenoid compounds
- Lawsone derivatives target the Wnt/β-catenin signaling pathway in multidrug-resistant acute lymphoblastic leukemia cells
- Artemisinin Derivatives Target Topoisomerase 1 and Cause DNA Damage in Silico and in Vitro
- North African Medicinal Plants Traditionally Used in Cancer Therapy
- Cytotoxicity and mode of action of a naturally occurring naphthoquinone, 2-acetyl-7-methoxynaphtho[2,3-b]furan-4,9-quinone towards multi-factorial drug-resistant cancer cells
- Antileukemic ancistrobenomine B and related 5,1'-coupled naphthylisoquinoline alkaloids from the Chinese liana Ancistrocladus tectorius
- Synthesis and cytotoxic activity of new artemisinin hybrid molecules against human leukemia cells
- Mode of Action Analyses of Neferine, a Bisbenzylisoquinoline Alkaloid of Lotus (Nelumbo nucifera) against Multidrug-Resistant Tumor Cells
- Answer to the comment of Hai Lu et al. regarding "Hepatotoxicity by combination treatment of temozolomide, artesunate and Chinese herbs in a glioblastoma multiforme patient: case report and review of the literature. Arch Toxicol (2016)"
- Drug Repurposing of the Anthelmintic Niclosamide to Treat Multidrug-Resistant Leukemia
- The road in front of us: Phytomedical research for the years to come
- Both Phenolic and Non-phenolic Green Tea Fractions Inhibit Migration of Cancer Cells
- Total coumarins of Hedyotis diffusa induces apoptosis of myelodysplastic syndrome SKM-1 cells by activation of caspases and inhibition of PI3K/Akt pathway proteins
- Anti-Proliferative and Apoptosis-Inducing Effect of Theabrownin against Non-small Cell Lung Adenocarcinoma A549 Cells
- Genomic and transcriptomic profiling of resistant CEM/ADR-5000 and sensitive CCRF-CEM leukaemia cells for unravelling the full complexity of multi- factorial multidrug resistance
- Systematic Review on Post-Traumatic Stress Disorder Among Survivors of the Wenchuan Earthquake
- Ancistectorine D, a naphthylisoquinoline alkaloid with antiprotozoal and antileukemic activities, and further 5,8′- and 7,1′-linked metabolites from the Chinese liana Ancistrocladus tectorius
- Substrate Specificity of Aglaia loheri Active Isolate towards P-glycoprotein in Multidrug-Resistant Cancer Cells
- Fatal Liver and Bone Marrow Toxicity by Combination Treatment of Dichloroacetate and Artesunate in a Glioblastoma Multiforme Patient: Case Report and Review of the Literature
- Antibacterial activities and structure-activity relationships of a panel of 48 compounds from Kenyan plants against multidrug resistant phenotypes
- Tumor Heterogeneity, Single-Cell Sequencing, and Drug Resistance
- Modulation of P-glycoprotein activity by novel synthetic curcumin derivatives in sensitive and multidrug-resistant T-cell acute lymphoblastic leukemia cell lines
- Cytotoxicity of 15 Cameroonian medicinal plants against drug sensitive and multi-drug resistant cancer cells
- Pharmacogenomics of Scopoletin in Tumor Cells
- Peptide aptamer identified by molecular docking targeting translationally controlled tumor protein in leukemia cells
- Hildebert Wagner Award Laureate announcement December 2015
- In Vivo Cardiotoxicity Induced by Sodium Aescinate in Zebrafish Larvae
- Cytotoxicity of an unprecedented brominated oleanolide and a new furoceramide from the Cameroonian spice, Echinops giganteus
- Interactions of human P-glycoprotein transport substrates and inhibitors at the drug binding domain: Functional and molecular docking analyses
- Production of rosmarinic acid and salvianolic acid B from callus culture of Salvia miltiorrhiza with cytotoxicity towards acute lymphoblastic leukemia cells
- Cytotoxicity of 91 Kenyan indigenous medicinal plants towards human CCRF-CEM leukemia cells
- A Five-year Survey of Cancer Prevalence in Sudan
- Activity of Artemisia annua and artemisinin derivatives, in prostate carcinoma
- Hormesis: Decoding Two Sides of the Same Coin
- Anticancer activity of cryptotanshinone on acute lymphoblastic leukemia cells
- Molecular Docking Analysis of Steroid-based Copper Transporter 1 Inhibitors
- The broad-spectrum antiinfective drug artesunate interferes with the canonical nuclear factor kappa B (NF-κB) pathway by targeting RelA/p65
- Activity of the antiestrogenic cajanin stilbene acid towards breast cancer
- Human ABCB1 confers cells resistance to cytotoxic guanidine alkaloids from Pterogyne nitens
- Cytotoxicity of a naturally occurring furoquinoline alkaloid and four acridone alkaloids towards multi-factorial drug-resistant cancer cells
- Cytotoxicity of 35 medicinal plants from Sudan towards sensitive and multidrug-resistant cancer cells
- Highly potent artemisinin-derived dimers and trimers: Synthesis and evaluation of their antimalarial, antileukemia and antiviral activities
- Cytotoxicity of anthraquinones from the roots of Pentas schimperi towards multi-factorial drug-resistant cancer cells
- New efficient artemisinin derived agents against human leukemia cells, human cytomegalovirus and Plasmodium falciparum: 2nd generation 1,2,4-trioxane-ferrocene hybrids
- Novel sequential stress model for functional dyspepsia: Efficacy of the herbal preparation STW5
- Bacteria-Derived Compatible Solutes Ectoine and 5α-Hydroxyectoine Act as Intestinal Barrier Stabilizers to Ameliorate Experimental Inflammatory Bowel Disease
- Miltirone Induces G2/M Cell Cycle Arrest and Apoptosis in CCRF-CEM Acute Lymphoblastic Leukemia Cells
- Cell cycle arrest and induction of apoptosis by cajanin stilbene acid from Cajanus cajun in breast cancer cells
- Kaempferol Is an Anti-Inflammatory Compound with Activity towards NF-xB Pathway Proteins
- Cytotoxicity of medicinal plants of the West-Canadian Gwich'in Native Americans towards sensitive and multidrug-resistant cancer cells
- Quantitative Structure-Activity Relationship and Molecular Docking of Artemisinin Derivatives to Vascular Endothelial Growth Factor Receptor 1
- Substituted Steroidal Compounds Containing Amino and Amido Groups Reverse Multidrug Resistance of Mouse T-Lymphoma and Two Human Prostate Cancer Cell Lines In Vitro
- Cytotoxicity of natural products and derivatives toward MCF-7 cell monolayers and cancer stem-like mammospheres
- Cytotoxicity of the indole alkaloid reserpine from Rauwoffia serpentina against drug-resistant tumor cells
- Cytotoxicity of cardiotonic steroids in sensitive and multidrug-resistant leukemia cells and the link with Na+/K+-ATPase
- Laurus nobilis L. Seed Extract Reveals Collateral Sensitivity in Multidrug-Resistant P-Glycoprotein-Expressing Tumor Cells
- Aptamers as a novel tool for diagnostics and therapy
- Shikonin and its derivatives inhibit the epidermal growth factor receptor signaling and synergistically kill glioblastoma cells in combination with erlotinib
- Pharmacogenomic Characterization of Cytotoxic Compounds from Salvia officinalis in Cancer Cells
- Synthetic cajanin stilbene acid derivatives inhibit c-MYC in breast cancer cells
- Dis-organizing Centrosomal Clusters: Specific Cancer Therapy for a Generic Spread?
- Phytochemical profile and bioactivity of traditional ayurvedic decoctions and hydro-alcoholic macerations of Boerhaavia diffusa L. and Curculigo orchioides Gaertn.
- Pharmacogenomic and molecular docking studies on the cytotoxicity of the natural steroid wortmannin against multidrug-resistant tumor cells
- Efficient Production of Isoflavonoids by Astragalus membranaceus Hairy Root Cultures and Evaluation of Antioxidant Activities of Extracts
- Posttraumatic stress disorder among earthquake survivors of the Wenchuan area (Sichuan, China)
- Pharmacogenetic Prediction of Individual Variability in Drug Response Based on CYP2D6, CYP2C9 and CYP2C19 Genetic Polymorphisms
- Cytotoxicity of the bisphenolic honokiol from Magnolia officinalis against multiple drug-resistant tumor cells as determined by pharmacogenomics and molecular docking
- Identification of new P-glycoprotein inhibitors derived from cardiotonic steroids
- Cytotoxic Benzophenanthridine and Furoquinoline Alkaloids from Zanthoxylum buesgenii (Rutaceae)
- Synthesis and Anti-Tumor Activity of Novel Aminomethylated Derivatives of Isoliquiritigenin
- Targeting epidermal growth factor receptors and downstream signaling pathways in cancer by phytochemicals
- Acupuncture and Herbal Medicine for Cancer Patients 2014
- Unprecedented new nonadecyl para-hydroperoxycinnamate isolated from Erythrina excelsa and its cytotoxic activity
- Negative pressure cavitation-microwave assisted preparation of extract of Pyrola incarnata Fisch. rich in hyperin, 2′-O-galloylhyperin and chimaphilin and evaluation of its antioxidant activity
- Resistance mechanisms of cancer cells to the novel vacuolar H+-ATPase inhibitor archazolid B
- Effects of Acupuncture on Leucopenia, Neutropenia, NK, and B Cells in Cancer Patients: A Randomized Pilot Study
- Up-regulation of cholesterol associated genes as novel resistance mechanism in glioblastoma cells in response to archazolid B
- Cytotoxicity and inhibition of P-glycoprotein by selected medicinal plants from Thailand
- The ability of molecular docking to unravel the controversy and challenges related to P-glycoprotein-a well-known, yet poorly understood drug transporter
- Cytotoxicity and modes of action of five Cameroonian medicinal plants against multi-factorial drug resistance of tumor cells
- Contributions from emerging transcriptomics technologies and computational strategies for drug discovery
- Tumor-specific blood serum factors as determinants of tumor growth.
- Cytotoxicity of Novel Sulfanilamides Towards Sensitive and Multidrug-resistant Leukemia Cells
- The lignan, (-)-sesamin reveals cytotoxicity toward cancer cells: Pharmacogenomic determination of genes associated with sensitivity or resistance
- Synthesis and study of cytotoxic activity of 1,2,4-trioxane- and egonol-derived hybrid molecules against Plasmodium falciparum and multidrug-resistant human leukemia cells
- Acupuncture and Herbal Medicine for Cancer Patients
- Pharmacogenomics of cantharidin in tumor cells
- Nitensidine A, a guanidine alkaloid from Pterogyne nitens, is a novel substrate for human ABC transporter ABCB1
- A phenolic ester from Aglaia loheri leaves reveals cytotoxicity towards sensitive and multidrug-resistant cancer cells
- Variation in Contents of Main Active Components and Antioxidant Activity in Leaves of Different Pigeon Pea Cultivars during Growth
- Cytotoxicity of Elaoephorbia drupifera and other Cameroonian medicinal plants against drug sensitive and multidrug resistant cancer cells
- Cytotoxicity and Pharmacogenomics of Medicinal Plants from Traditional Korean Medicine
- Integration of Different "-omics" Technologies Identifies Inhibition of the IGF1R-Akt-mTOR Signaling Cascade Involved in the Cytotoxic Effect of Shikonin against Leukemia Cells
- Antiproliferative and Erythroid Differentiation of Piperazine and Triphenyl Derivatives Against K-562 Human Chronic Myelogenous Leukemia
- Novel artemisinin derivatives with potential usefulness against liver/colon cancer and viral hepatitis
- Safety and Efficacy Field Study of Artesunate for Dogs with Non-resectable Tumours
- Microwave-Assisted Synthesis of New Selenazole Derivatives with Antiproliferative Activity
- Cajaninstilbene acid (CSA) exerts cytoprotective effects against oxidative stress through the Nrf2-dependent antioxidant pathway
- Objectifying Acupuncture Effects by Lung Function and Numeric Rating Scale in Patients Undergoing Heart Surgery
- Dihydroquercetin (DHQ) Induced HO-1 and NQO1 Expression against Oxidative Stress through the Nrf2-Dependent Antioxidant Pathway
- Polo-like kinase 1 as target for cancer therapy
- UV-Induced Changes of Active Components and Antioxidant Activity in Postharvest Pigeon Pea [Cajanus cajan (L.) Millsp.] Leaves
- Alkamides from Echinacea angustifolia Interact with P-Glycoprotein of Primary Brain Capillary Endothelial Cells Isolated from Porcine Brain Blood Vessels
- Identification by High-throughput In Silico Screening of Radio-protecting Compounds Targeting the DNA-binding Domain of the Tumor Suppressor p53
- Qigong therapy for physiotherapists suffering from burnout: a preliminary study
- Mode of Cell Death Induction by Pharmacological Vacuolar H+-ATPase (V-ATPase) Inhibition
- Aspidin PB, a phloroglucinol derivative, induces apoptosis in human hepatocarcinoma HepG2 cells by modulating PI3K/Akt/GSK3β pathway
- Molecular interaction of artemisinin with translationally controlled tumor protein (TCTP) of Plasmodium falciparum
- Inhibition in vivo of the activity of botulinum neurotoxin A by small molecules selected by virtual screening
- Growth-dependent release of carbohydrate metabolism-related and antioxidant enzymes from Staphylococcus aureus strain 6 as determined by proteomic analysis
- Effects of qigong on performance-related anxiety and physiological stress functions in transverse flute music schoolchildren: a feasibility study
- New artesunic acid homodimers: Potent reversal agents of multidrug resistance in leukemia cells
- Microarray-based mRNA Expression Profiling of Leukemia Cells Treated with the Flavonoid, Casticin
- Polyhydroxylated Steroidal Glycosides from Paris polyphylla
- Anti-Infective and Antiproliferative Potential of African Medicinal Plants
- Can heat and cold be parameterized? Clinical data of a preliminary study
- In Vitro Antioxidant and Antimicrobial Activity of Extracts from Morus alba L. Leaves, Stems and Fruits
- The European directive on traditional herbal medicinal products: friend or foe for plant-based therapies?
- Utilizing inherent fluorescence of therapeutics to analyze real-time uptake and multi-parametric effector kinetics
- Effects of Scrophularia ningpoensis Hemsl. on Inhibition of Proliferation, Apoptosis Induction and NF-κB Signaling of Immortalized and Cancer Cell Lines
- In Silico Analysis of Microarray-Based Gene Expression Profiles Predicts Tumor Cell Response to Withanolides
- Artesunate Induces Oxidative DNA Damage, Sustained DNA Double-Strand Breaks, and the ATM/ATR Damage Response in Cancer Cells
- Targeting the mitochondrial pathway to induce apoptosis/necrosis through ROS by a newly developed Schiff's base to overcome MDR in cancer
- Antibacterial Activity and Cytotoxicity of Selected Egyptian Medicinal Plants
- Anticancer activity of Salvia officinalis essential oil against HNSCC cell line (UMSCC1)
- Cytotoxic activity of secondary metabolites derived from Artemisia annua L. towards cancer cells in comparison to its designated active constituent artemisinin
- Pharmacogenomic determination of genes associated with sensitivity or resistance of tumor cells to curcumin and curcumin derivatives
- Establishment and comparative characterization of novel squamous cell non-small cell lung cancer cell lines and their corresponding tumor tissue
- Pharmacogenomics of Cameroonian traditional herbal medicine for cancer therapy
- Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1
- Inhibition of Tumor Angiogenesis by Antibodies, Synthetic Small Molecules and Natural Products
- Catalytic Synthesis of α-Oxoketene S,S-Acetals in a Wet Ionic Liquid [Bmim]Cl/H2O Homogeneous System
- Efficient Lewis Acid Ionic Liquid-Catalyzed Synthesis of the Key Intermediate of Coenzyme Q10 under Microwave Irradiation
- Chemistry and Pharmacology of Neglected Helminthic Diseases
- Molecular docking and pharmacogenomics of Vinca alkaloids and their monomeric precursors, vindoline and catharanthine
- Vaccination and Antiviral Treatment of Neglected Diseases Caused by Flaviviral Infections
- Toxicogenomics for the Prediction of Toxicity Related to Herbs from Traditional Chinese Medicine
- Transcript profiling identifies novel key players mediating the growth inhibitory effect of NS-398 on human pancreatic cancer cells
- Natural Products Derived from Traditional Chinese Medicine as Novel Inhibitors of the Epidermal Growth Factor Receptor
- MicroRNA expression profile of MCF-7 human breast cancer cells and the effect of green tea polyphenon-60.
- Therapeutic and Diagnostic Applications of Nanoparticles
- EVALUATION OF DRUG TRANSPORTERS' SIGNIFICANCE FOR MULTIDRUG RESISTANCE IN HEAD AND NECK SQUAMOUS CELL CARCINOMA
- Activity investigation of pinostrobin towards herpes simplex virus-1 as determined by atomic force microscopy
- Fighting mycobacterial infections by antibiotics, phytochemicals and vaccines
- Cancer Therapy with Natural Products and Medicinal Plants
- Sensitivity and resistance towards isoliquiritigenin, doxorubicin and methotrexate in T cell acute lymphoblastic leukaemia cell lines by pharmacogenomics
- Identification of serpin (alpha-1-antitrypsin) as serum growth inhibitory factor in murine ehrlich carcinoma by proteomics.
- Design of novel artemisinin-like derivatives with cytotoxic and anti-angiogenic properties
- Inhibition of P-glycoprotein at the blood-brain barrier by phytochemicals derived from traditional Chinese medicine.
- Personalized Cancer Medicine: From Molecular Diagnostics to Targeted Therapy with Natural Products
- Cytotoxicity of Artesunic Acid Homo- and Heterodimer Molecules toward Sensitive and Multidrug-Resistant CCRF-CEM Leukemia Cells
- Enhanced extraction of astragalosides from Radix Astragali by negative pressure cavitation-accelerated enzyme pretreatment
- Strategies for Overcoming Chemotherapy Resistance in Enterohepatic Tumours
- Fighting Cancer with Red Wine? Molecular Mechanisms of Resveratrol
- Berberine Inhibits Cell Growth and Mediates Caspase-Independent Cell Death in Human Pancreatic Cancer Cells
- A petrol ether extract of the roots of Onosma paniculatum induces cell death in a caspase dependent manner
- First evidence that the antimalarial drug artesunate inhibits invasion and in vivo metastasis in lung cancer by targeting essential extracellular proteases
- Pharmacogenomic Identification of c-Myc/Max-Regulated Genes Associated with Cytotoxicity of Artesunate towards Human Colon, Ovarian and Lung Cancer Cell Lines
- Antioxidant Activities and Xanthine Oxidase Inhibitory Effects of Extracts and Main Polyphenolic Compounds Obtained from Geranium sibiricum L.
- Inhibition of epidermal growth factor receptor-overexpressing cancer cells by camptothecin, 20-(N,N-diethyl) glycinate
- Factors determining sensitivity or resistance of tumor cell lines towards artesunate
- Traditional Chinese Medicines (TCMs) for Molecular Targeted Therapies of Tumours
- Toxicity of the antimalarial artemisinin and its dervatives
- Inhibition of inducible nitric oxide synthase by bis(helenalinyl)glutarate in RAW264.7 macrophages
- Plasma pharmacokinetics and tissue distribution study of cajaninstilbene acid in rats by liquid chromatography with tandem mass spectrometry
- Cytotoxic Activity of Curcumin towards CCRF-CEM Leukemia Cells and Its Effect on DNA Damage
- Ethnobotanical survey and cytotoxicity testing of plants of South-western Nigeria used to treat cancer, with isolation of cytotoxic constituents from Cajanus cajan Millsp leaves
- Neglected Diseases Caused By Bacterial Infections
- Inhibition of epidermal growth factor receptor over-expressing cancer cells by the aphorphine-type isoquinoline alkaloid, dicentrine
- Rapid microwave-assisted transesterification of yellow horn oil to biodiesel using a heteropolyacid solid catalyst
- Determination of paclitaxel and its analogues in the needles of Taxus species by using negative pressure cavitation extraction followed by HPLC-MS-MS
- Microarray analysis of gene expression in medicinal plant research.
- Chemical composition and biological activity of the essential oil obtained from Bupleurum marginatum (Apiaceae)
- Natural products pave their way in cancer therapy
- Detection and Characterization of a Glutathione Conjugate of a Novel Copper Complex
- Induction of resistance to murine tumor development is associated with alterations in the glycosylation of blood serum proteins
- Negative-pressure cavitation extraction for the determination of flavonoids in pigeon pea leaves by liquid chromatography-tandem mass spectrometry
- Drug Resistance of Human Immunodeficiency Virus and Overcoming it by Natural Products
- Gene expression profiling identifies novel key players involved in the cytotoxic effect of Artesunate on pancreatic cancer cells
- The Role of Downstream Signaling Pathways of the Epidermal Growth Factor Receptor for Artesunate's Activity in Cancer Cells
- Lipid rafts play an important role in the vesicular stomatitis virus life cycle
- Cytotoxic Activity of Isoliquiritigenin towards CCRF-CEM Leukemia Cells and its Effect on DNA Damage
- The Antibacterial Activity of Clove Essential Oil Against Propionibacterium acnes and Its Mechanism of Action
- Determination and quantification of astragalosides in Radix Astragali and its medicinal products using LC-MS
- Drug Resistance in Plasmodium: Natural Products in the Fight Against Malaria
- Natural products as promising drug candidates for the treatment of hepatitis B and C
- Molecular Mechanisms of and Clinical Evidence for Interactions Between Natural Products and Drugs
- Molecular Mechanisms Underlying St. John's Wort Drug Interactions
- Human cytomegalovirus: Drug resistance and new treatment options using natural products
- Herpes simplex virus: Drug resistance and new treatment options using natural products (Review)
- Artesunate derived from traditional Chinese medicine induces DNA damage and repair
- Activation of the mitochondria-driven pathway of apoptosis in human PC-3 prostate cancer cells by a novel hydrophilic paclitaxel derivative, 7-xylosyl-10-deacetylpaclitaxel
- Role of transporter genes in cisplatin resistance
- Microarray-based expression of DNA repair genes does not correlate with growth inhibition of cancer cells by natural products derived from traditional Chinese medicine.
- Hemoglobin-associated proteins isolated from blood serum of Ehrlich carcinoma-bearing mice
- Cytotoxicity and p-glycoprotein modulating effects of quinolones and indoloquinazolines from the Chinese herb Evodia rutaecarpa
- Determination of vitexin and isovitexin in pigeonpea using ultrasonic extraction followed by LC-MS
- Phytochemistry and pharmacogenomics of natural products derived from traditional Chinese medicine and Chinese materia medica with activity against tumor cells
- Anti-cancer natural product library from traditional Chinese medicine
- In vitro cytotoxicity and P-glycoprotein modulating effects of geranylated Furocoumarins from Tetradium daniellii
- Separation of 7-xylosyl-10-deacetyl paclitaxel and 10-deacetylbaccatin III from the remainder extracts free of paclitaxel using macroporous resins
- Role of Transferrin Receptor and the ABC Transporters ABCB6 and ABCB7 for Resistance and Differentiation of Tumor Cells towards Artesunate
- Pharmacogenomics of a traditional Japanese herbal medicine (Kampo) for cancer therapy.
- Molecular target-guided tumor therapy with natural products derived from traditional Chinese medicine
- Three-Dimensional Modeling of Glucose-6-phosphate Dehydrogenase-Deficient Variants from German Ancestry
- Effect of cantharidin, cephalotaxine and homoharringtonine on "in vitro" models of hepatitis B virus (HBV) and bovine viral diarrhoea virus (BVDV) replication
- Chemotherapy-induced resistance by ATP-binding cassette transporter genes
- Modulation of human BCRP (ABCG2) activity by anti-HIV drugs
- Diagnosis and therapy of oral squamous cell carcinoma
- Willmar Schwabe Award 2006: Antiplasmodial and antitumor activity of arternisinin - From bench to bedside
- Cytotoxic and new tetralone derivatives from Berchemia floribunda (WALL.) BRONGN.
- New glycosides from Tetracentron sinense and their cytotoxic activity
- A novel copper complex induces ROS generation in doxorubicin resistant Ehrlich ascitis carcinoma cells and increases activity of antioxidant enzymes in vital organs in vivo
- Optimization of luteolin separation from pigeonpea [Cajanus cajan (L.) Millsp.] leaves by macroporous resins
- ABCA3 as a possible cause of drug resistance in childhood acute myeloid leukemia
- Activity-guided isolation of scopoletin and isoscopoletin, the inhibitory active principles towards CCRF-CEM leukaemia cells and multi-drug resistant CEM/ADR5000 cells, from Artemisia argyi
- Antiviral effect of artemisinin from Artemisia annua against a model member of the Flaviviridae family, the bovine viral diarrhoea virus (BVDV)
- Expression profiling of ATP-binding cassette transporters in childhood T-cell acute lymphoblastic leukemia
- Overcoming drug-resistant cancer by a newly developed copper chelate through host-protective cytokine-mediated apoptosis
- Part 1: Pharmacognosy and molecular pharmacology of small molecules of natural origin for cancer therapy and chemoprevention
- Molecular pharmacology and pharmacogenomics of artemisinin and its derivatives in cancer cells
- Reversal of drug resistance in P-glycoprotein-expressing T-cell acute lymphoblastic CEM leukemia cells by copper N-(2-hydroxy acetophenone) glycinate and oxalyl bis (N-phenyl) hydroxamic acid
- Microarray expression profiles of angiogenesis-related genes predict tumor cell response to artemisinins
- Microarray Expression Profiling of ABC Transporters in Human Breast Cancer.
- Artesunate in the treatment of metastatic uveal melanoma - first experiences
- Role of glucose-6-phosphate dehydrogenase for oxidative stress and apoptosis
- The anti-malaria drug artesunate inhibits replication of cytomegalovirus in vitro and in vivo
- Relationship between molecular variants and clinical manifestions in twelve glucose-6-phosphate dehydrogenase-deficient patients in Jordan
- Effect of artemisinin/artesunate as inhibitors of hepatitis B virus production in an "in vitro" replicative system
- Molecular modeling of O6-methylguanine-DNA methyltransferase mutant proteins encoded by single nucleotide polymorphisms
- Glutathione-related enzymes contribute to resistance of tumor cells and low toxicity in normal organs to artesunate
- Pharmacogenetics for individualized cancer chemotherapy
- FISH studies on the telomeric regions of the T-cell acute lymphoblastic leukemia cell line CCRF-CEM
- Molecular modes of action of cantharidin in tumor cells
- Indole and carbazole alkaloids from Glycosmis montana with weak anti-HIV and cytotoxic activities
- Genomic gain of the epidermal growth factor receptor harboring band 7p12 is part of a complex pattern of genomic imbalances in oral squamous cell carcinomas
- Microarray-based prediction of cytotoxicity of tumor cells to cantharidin
- Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron
- Glucose-6-phosphate dehydrogenase (G6PD) deficiency-type Zurich: a splice site mutation as an uncommon mechanism producing enzyme deficiency
- Homozygous deletions of CDKN2A caused by alternative mechanisms in various human cancer cell lines
- Activity of novel plant extracts against medullary thyroid carcinoma cells
- Oxidative stress response of tumor cells: microarray-based comparison between artemisinins and anthracyclines
- Microarray-based Prediction of Cytotoxicity of Tumor Cells to Arsenic Trioxide.
- Inverse correlation of epidermal growth factor receptor messenger RNA induction and suppression of anchorage-independent growth by OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in glioblastoma multiforme cell lines
- Combination-treatment of glioblastoma multiforme cell lines with the anti-malarial artesunate and the epidermal growth factor receptor tyrosine kinase inhibitor OSI-774
- Lung Cancer Protein Expression Profiles of Smokers and Non-Smokers.
- Identification of gene expression profiles predicting tumor cell response to L-alanosine
- Protein Expression Profiles Indicative for Drug Resistance of Kidney Carcinoma.
- Analysis of single nucleotide polymorphism C3435T of the multidrug resistance gene MDR1 in acute lymphoblastic leukemia
- MDR1 single nucleotide polymorphism C3435T in normal colorectal tissue and colorectal carcinomas detected by MALDI-TOF mass spectrometry
- Molecular modes of action of cephalotaxine and homoharringtonine from the coniferous tree Cephalotaxus hainanensis in human tumor cell lines
- Comparative M-FISH and CGH analyses in sensitive and drug-resistant human T-cell acute leukemia cell lines
- Specific patterns of DNA copy number gains and losses in eight new glioblastoma multiforme cell lines
- Synergism between rViscumin and cisplatin is not dependent on ERCC-1 expression
- Adenosine triphosphate-binding cassette transporter genes in ageing and age-related diseases
- Genomic imbalances in drug-resistant T-cell acute lymphoblastic CEM leukemia cell lines
- Activity of ascaridol from the anthelmintic herb Chenopodium anthelminticum L. against sensitive and multidrug resistant tumor cells
- Protein expression profiles indicative for drug resistance of non-small cell lung cancer
- Protein expression profile of primary human squamous cell lung carcinomas indicative of the incidence of metastases
- Genomic imbalances in T-cell acute lymphoblastic leukemia cell lines
- mRNA expression profiles for the response of human tumor cell lines to the antimalarial drugs artesunate, arteether, and artemether
- Protein expression profile of newly diagnosed acute lymphoblastic leukemia in children developing relapses
- Protein expression profiles of non-small cell lung carcinomas:: Correlation with histological subtype
- Activity of Drugs from Traditional Chinese Medicine toward Sensitive and MDR1- or MRP1-Overexpressing Multidrug-Resistant Human CCRF-CEM Leukemia Cells
- Use of CpG island microarrays to identify colorectal tumors with a high degree of concurrent methylation
- Antiviral activity of artesunate towards wild-type, recombinant, and ganciclovir-resistant human cytomegaloviruses
- Methylthioadenosine phosphorylase as target for chemoselective treatment of T-cell acute lymphoblastic leukemic cells
- Interleukin-6 affects melphalan-induced DNA damage and repair in human multiple myeloma cells
- Expression profile of genes in non-small cell lung carcinomas from long-term surviving patients
- Expression profile of proteins involved in the xenotransplantability of non-small cell lung cancers into athymic nude mice
- The Human ATP-Binding Cassette Transporter Genes From the Bench to the Bedside
- [Hope for gene therapy. Is this the future of tumor treatment?].
- 5-azacytidine modulates the response of sensitive and multidrug-resistant K562 leukemic cells to cytostatic drugs
- Prognostic impacts of cytogenetic findings in clear cell renal cell carcinoma:: Gain of 5q31-qter predicts a distinct clinical phenotype with favorable prognosis
- Differential expression of the heat shock protein 70 in the histological compartments of nephroblastomas
- Differential expression of the drug resistance markers DNA topoisomerase IIα and glutathione S-transferase-π in the histological compartments of Wilms' tumors
- Differential expression of the lung resistance-related protein/major vault protein in the histological compartments of nephroblastomas
- Differential expression of the multidrug resistance-related protein MRP1 in the histological compartments of nephroblastomas
- The anti-malarial artesunate is also active against cancer
- DNA damage and apoptosis in mononuclear cells from glucose-6-phosphate dehydrogenase-deficient patients (G6PD Aachen variant) after UV irradiation
- Damage of the kinesin heavy chain gene contributes to the antagonism of cisplatin and paclitaxel
- Biomedical technology in Franconia
- Molecular characterization of a German variant of glucose-6-phosphate dehydrogenase deficiency (G6PD Aachen)
- Leptin contributes to the protection of human leukemic cells from cisplatinum cytotoxicity
- Impact of viral oncogenesis on responses to anti-cancer drugs and irradiation
- Testing for tumor drug resistance in the age of molecular medicine. A contribution to the Debate Round-Table on phenotypic and genotypic analyses of multidrug resistance (MDR) in clinical hospital practice
- Apoptosis and resistance to daunorubicin in human leukemic cells
- SISTER-CHROMATID EXCHANGE INDUCING DNA LESIONS AND DEPRESSION OF ACTIVATION MARKERS ON THE SURFACE OF CULTURED PERIPHERAL-BLOOD MONONUCLEAR-CELLS AFTER THE ADDITION OF STREPTOCOCCAL PYROGENIC EXOTOXIN-A AND EXOTOXINC
- Detection of apoptosis in KG-1a leukemic cells treated with investigational drugs
- Anti-Fas/Apo-1 monoclonal antibody CH-11 depletes glutathione and kills multidrug-resistant human leukemic cells
- INDUCTION OF P-GLYCOPROTEIN, GLUTATHIONE-S-TRANSFERASE-PI, CATALASE, C-FOS AND C-ERBB1 IN RODENT CELL-LINES AFTER EXPOSURE TO DOXORUBICIN, ETHANOL AND CAFFEINE
- EXPRESSION OF APOPTOSIS-RELATED ONCOPROTEINS AND MODULATION OF APOPTOSIS BY CAFFEINE IN HUMAN LEUKEMIC-CELLS
- INCREASED INDUCTION OF APOPTOSIS IN MONONUCLEAR-CELLS OF A GLUCOSE-6-PHOSPHATE-DEHYDROGENASE DEFICIENT PATIENT
- OVERCOMING DRUG-RESISTANCE OF TUMORS
- INTRINSIC OVEREXPRESSION OF 2 DIFFERENT MECHANISMS OF RESISTANCE TO CHEMOTHERAPY (P-GLYCOPROTEIN AND GST-PI) IN HUMAN ENDOMETRIAL CARCINOMA
- INCREASE OF ALKALINE-PHOSPHATASE IN MULTIDRUG-RESISTANT TUMOR-CELLS AND THEIR CROSS-RESISTANCE TO 6-THIOGUANINE
- MODULATION OF P-GLYCOPROTEIN-MEDIATED MULTIDRUG-RESISTANCE BY MONOCLONAL-ANTIBODIES, IMMUNOTOXINS OR ANTISENSE OLIGODEOXYNUCLEOTIDES IN KIDNEY CARCINOMA AND NORMAL KIDNEY-CELLS
- REVERSAL OF INHERENT MULTIDRUG-RESISTANCE IN PRIMARY HUMAN RENAL-CELL CARCINOMA CELL-CULTURES BY S-9788
- REVERSAL OF DOXORUBICIN-RESISTANCE IN SARCOMA-180 TUMOR-CELLS BY INHIBITION OF DIFFERENT RESISTANCE MECHANISMS
- EXPRESSION OF PROTEIN-KINASE-C IN HUMAN RENAL-CELL CARCINOMA-CELLS WITH INHERENT RESISTANCE TO DOXORUBICIN
- HIGH-RATE OF EXPRESSION OF MULTIDRUG RESISTANCE-ASSOCIATED P-GLYCOPROTEIN IN HUMAN ENDOMETRIAL CARCINOMA AND NORMAL ENDOMETRIAL TISSUE
- EXPRESSION OF RESISTANCE FACTORS (P-GLYCOPROTEIN, GLUTATHIONE-S-TRANSFERASE-PI, AND TOPOISOMERASE-II) AND THEIR INTERRELATIONSHIP TO PROTOONCOGENE PRODUCTS IN RENAL-CELL CARCINOMAS
- EXPRESSION OF SEVERAL RESISTANCE MECHANISMS IN UNTREATED HUMAN KIDNEY AND LUNG CARCINOMAS
- RESISTANCE MECHANISMS IN MURINE TUMORS WITH ACQUIRED MULTIDRUG RESISTANCE
- OVEREXPRESSION OF C-FOS AND C-ERBB1 ENCODED PROTEINS IN SQUAMOUS-CELL CARCINOMAS OF THE LUNG OF SMOKERS
- IMMUNOCYTOCHEMICAL DETECTION OF ONCOPROTEINS IN ANIMAL AND HUMAN TUMOR LINES WITH ACQUIRED OR INHERENT MULTIDRUG RESISTANCE
- ANTIBODY-DIRECTED THERAPY OF MULTIDRUG-RESISTANT TUMOR-CELLS
- ONCOPROTEIN (C-MYC, C-ERBB1, C-ERBB2, C-FOS) AND SUPPRESSOR GENE-PRODUCT (P53) EXPRESSION IN SQUAMOUS-CELL CARCINOMAS OF THE LUNG - CLINICAL AND BIOLOGICAL CORRELATIONS
- IMMUNOHISTOCHEMICAL DETECTION OF P-GLYCOPROTEIN, GLUTATHIONE-S-TRANSFERASE AND DNA TOPOISOMERASE-II IN HUMAN TUMORS
- CIRCUMVENTION OF MULTIDRUG RESISTANCE IN HUMAN KIDNEY AND KIDNEY CARCINOMA INVITRO
- SELECTIVE GROWTH-INHIBITION OF MULTIDRUG-RESISTANT CHO-CELLS BY THE MONOCLONAL-ANTIBODY 265/F4
- OVEREXPRESSION OF P-GLYCOPROTEIN IN HUMAN LUNG-CARCINOMA XENOGRAFTS AFTER FRACTIONATED-IRRADIATION INVIVO
- RESISTANCE TO DOXORUBICIN IN TUMOR-CELLS INVITRO AND INVIVO AFTER PRETREATMENT WITH VERAPAMIL
- REVERSING MULTIDRUG RESISTANCE IN L1210 TUMOR-CELLS BY HYCANTHONE OR CHLOROPHENOXAMINE INVITRO AND INVIVO
- DETECTION OF DRUG-RESISTANCE AND P-GLYCOPROTEIN IN HUMAN RENAL-CELL CARCINOMAS
- OVEREXPRESSION OF P-GLYCOPROTEIN IN RAT HEPATOCELLULAR CARCINOMAS INDUCED WITH N-NITROSOMORPHOLINE
- RELATIONSHIP OF DNA PLOIDY TO CHEMORESISTANCE OF TUMORS AS MEASURED BY INVITRO TESTS
- CORRELATIONS BETWEEN NATURAL-RESISTANCE TO DOXORUBICIN, PROLIFERATIVE ACTIVITY, AND EXPRESSION OF P-GLYCOPROTEIN-170 IN HUMAN KIDNEY TUMOR-CELL LINES
- DETECTION OF THE MULTIDRUG RESISTANT PHENOTYPE IN HUMAN-TUMORS BY MONOCLONAL-ANTIBODIES AND THE STREPTAVIDIN BIOTINYLATED PHYCOERYTHRIN COMPLEX METHOD
- ACQUIRED DRUG-RESISTANCE IN HUMAN-LUNG CARCINOMA XENOGRAFTS
- DETECTION OF P-GLYCOPROTEIN IN HUMAN LEUKEMIAS USING MONOCLONAL-ANTIBODIES
- DETECTION OF DRUG-RESISTANCE IN HUMAN OVARIAN-CARCINOMA
- INDUCED MULTIDRUG RESISTANCE IN MURINE LEUKEMIA-L1210 AND ASSOCIATED CHANGES IN A SURFACE-MEMBRANE GLYCOPROTEIN
- INDUCED MULTIDRUG-RESISTANCE IN MURINE SARCOMA 180 CELLS GROWN-INVITRO AND INVIVO AND ASSOCIATED CHANGES IN EXPRESSION OF MULTIDRUG-RESISTANCE DNA-SEQUENCES AND MEMBRANE-GLYCOPROTEINS
- RAPID DETECTION ASSAYS FOR MULTIDRUG RESISTANCE
- IMMUNOCYTOCHEMICAL DETECTION OF A RESISTANCE-ASSOCIATED GLYCOPROTEIN IN TISSUE-CULTURE CELLS, ASCITES TUMORS AND HUMAN-TUMOR XENOGRAFTS BY MAB 265 F4
- DETECTION OF MURINE S180 CELLS EXPRESSING A MULTIDRUG RESISTANCE PHENOTYPE USING DIFFERENT INVITRO TEST SYSTEMS AND A MONOCLONAL-ANTIBODY
- Breaking the spores of the fungus Ganoderma lucidum by supercritical CO2
- The impact of "omics" technologies for grapevine (Vitis vinifera) research
- Tumor preventive properties of selected marine pigments against colon and breast cancer
- Shikonin impairs the growth of docetaxel-resistant prostate cancer cells by necroptosis.
- Artesunate reduces tumor growth and induces different kinds of cell death in docetaxel-resistant prostate carcinoma cells
- Cytotoxic polyoxygenated isopimarane diterpenoids from the edible rhizomes of Kaempferia galanga (kencur)
- Synthesis of novel xanthone and acridone carboxamides with potent antiproliferative activities
- The new journal Phytomedicine Plus to meet the increasing demand for publishing in the fields of phytotherapy and phytopharmacology
- Medicinal plants and phytochemicals against multidrug-resistant tumor cells expressing ABCB1, ABCG2, or ABCB5: a synopsis of 2 decades
- Two new flavonoids from Dracaena usambarensis Engl.
- Multifactorial anti-inflammatory activity of STW5-II towards murine intestinal organoids
- New phenolics, cytotoxicity and chemosystematic significance of Atriplex semibaccata
- Interviews and personal stories: A humanities approach in pharmaceutical education
- Gastroprotective effects of ursolic acid isolated from Ochrosia elliptica on ethanol-induced gastric ulcer in rats
- Artesunate reduces tumor growth in sunitinb-resistant renal cell carcinoma cells
- ANTI-INFLAMMATORY AND EPITHELIAL PROTECTIVE EFFECTS OF HERBAL PREPARATION STW5-II ON MOUSE INTESTINAL ORGANOIDS
- Biotechnology Applications of Plant Callus Cultures
- Euonymus maackii Rupr. Seed oil as a new potential non-edible feedstock for biodiesel
- Beyond malaria: Second career of artesunate as cancer drug
- Catalytic transesterification of Pistacia chinensis seed oil using HPW immobilized on magnetic composite graphene oxide/cellulose microspheres
- Phytochemical constituents and chemosystematic significance of Pulicaria jaubertii E.Gamal-Eldin (Asteraceae)
- Heterocycles 44. Synthesis, characterization and anticancer activity of new thiazole ortho-hydroxychalcones
- Polyphenolic compounds, antioxidant and anti-inflammatory effects of Abeliophyllum distichum Nakai extract
- The anticancer activity of the antimalarial artesunate
- Improvement of resveratrol production from waste residue of grape seed by biotransformation of edible immobilized Aspergillus oryzae cells and negative pressure cavitation bioreactor using biphasic ionic liquid aqueous system pretreatment
- Neuroprotection and antioxidative effects of Sijunzi Tang Decoction in the nematode Caenorhabditis elegans
- Shikonin causes cancer cell death by inducing mitochondria! dysfunction
- Fishing for artemisin-ininteracting proteins from human nasopharyngeal cancer cells
- Development of resistance towards artesunate in MDA-MB-231 human breast cancer cells
- Synthesis and Cytotoxicity of 1,4-Dihydropyridines and an Unexpected 1,3-Oxazin-6-one
- Correlation of cultivation time of Panax ginseng with metabolic profiles of nine ginsenosides and mRNA expression of genes encoding major biosynthetic enzymes
- Negative-pressure cavitation coupled with aqueous two-phase extraction and enrichment of flavonoids and stilbenes from the pigeon pea leaves and the evaluation of antioxidant activities
- Discovering New Underlying Mechanisms in the Treatment of Functional Dyspepsia With the Herbal Preparation, STW5 Using a Novel Sequential Stress Model
- Receptor Modulation and MAP-Kinase Signaling Induced by STW5 and by the Proton-Pump Inhibitor Omeprazol in a Rat Model for Gastroesophageal Reflux Disease and in HET1A-Cells
- Ethylene increases accumulation of compatible solutes and decreases oxidative stress to improve plant tolerance to water stress in Arabidopsis
- Modulation of the pharmacokinetics, therapeutic and adverse effects of NSAIDs by Chinese herbal medicines
- INHIBITION OF P-GLYCOPROTEIN IN CANCER CELLS BY SYNTHETIC AND NATURAL COMPOUNDS
- Phytochemicals for the treatment of inflammatory bowel diseases
- Free radical scavenging capability, antioxidant activity and chemical constituents of Pyrola incarnata Fisch leaves
- Antioxidant properties, superoxide dismutase and glutathione reductase activities in HepG2 cells with a fungal endophyte producing apigenin from pigeon pea [Cajanus cajan (L.) Millsp.]
- Enzyme pretreatment and negative pressure cavitation extraction of genistein and apigenin from the roots of pigeon pea [Cajanus cajan (L.) Millspl and the evaluation of antioxidant activity
- Potential of 'Omics' Technologies for Implementation in Research on Phytotherapeutical Toxicology
- Molecular approaches for individualized tumor therapy with standard drugs, phytochemicals, and medicinal herbs
- Enhanced extraction of isoflavonoids from Radix Astragali by incubation pretreatment combined with negative pressure cavitation and its antioxidant activity
- Negative pressure cavitation accelerated processing for extraction of main bioactive flavonoids from Radix Scutellariae
- Resin adsorption as a means to enrich rare stilbenes and coumarin from pigeon pea leaves extracts
- Preparation and antioxidant activity of Radix Astragali residues extracts rich in calycosin and formononetin
- Negative-pressure cavitation extraction of cajaninstilbene acid and pinostrobin from pigeon pea [Cajanus cajan (L.) Millsp.] leaves and evaluation of antioxidant activity
- Virtual screening of small molecule inhibitors towards the tumor suppressor p53 to overcome radioresistance of nasopharyngeal carcinoma cells
- Enzymatic water extraction of taxifolin from wood sawdust of Larix gmelini (Rupr.) Rupr. and evaluation of its antioxidant activity
- Negative pressure cavitation extraction and antioxidant activity of genistein and genistin from the roots of pigeon pea [Cajanus cajan (L.) Millsp.]
- Rapid microwave-assisted transesterification for the preparation of fatty acid methyl esters from the oil of yellow horn (Xanthoceras sorbifolia Bunge.)
- Antimicrobial activity and cytotoxicity towards cancer cells of Melaleuca alternifolia (tea tree) oil
- Immunohistological detection of P-glycoprotein 170 in multidrug resistant cells
- P-GLYCOPROTEIN AS MARKER FOR MULTIDRUG-RESISTANCE IN TUMORS AND NORMAL-TISSUES
- CLINICAL RELEVANCE OF THE MDR-1 GENE AND ITS GENE-PRODUCT, P-GLYCOPROTEIN, FOR CANCER-CHEMOTHERAPY - A METAANALYSIS
- Curcumin Shows Promising Anti-Tumor Effects in Mice, at Least
- Quality management for biomedical research in Germany
- Didactics of molecular ecology
- IS THERE A REALISTIC CHANCE FOR THE CLINICAL MODULATION OF MULTIDRUG-RESISTANCE
- Artesunate Inhibits the Growth Behavior of Docetaxel-Resistant Prostate Cancer Cells
- Der Virtuelle Campus Rheinland-Pfalz.
- Selective growth-inhibition of multidrug-resistant CHO-cells by the monoclonal antibody 265/F4
- Molekulare Pharmakologie und Toxikologie Biologische Grundlagen von Arzneimitteln und Giften
- Resistance to Targeted ABC Transporters in Cancer
- Biodiversity, Natural Products and Cancer Treatment
- Shikonin Inhibits Cell Growth of Sunitinib-Resistant Renal Cell Carcinoma by Activating the Necrosome Complex and Inhibiting the AKT/mTOR Signaling Pathway
- In Silico and In Vitro Identification of Pan-Coronaviral Main Protease Inhibitors from a Large Natural Product Library
- Cancer combination therapy with carnosic acid
- Plant cell cultures: An enzymatic tool for polyphenolic and flavonoid transformations
- Fuzi decoction ameliorates pain and cartilage degeneration of osteoarthritic rats through PI3K-Akt signaling pathway and its clinical retrospective evidence
- Transcriptomics, molecular docking, and cross-resistance profiling of nobiletin in cancer cells and synergistic interaction with doxorubicin upon SOX5 transfection
- Regulation of endoplasmic reticulum stress by hesperetin: Focus on antitumor and cytoprotective effects
- Liver and gastrointestinal cancers
- Individualized Tumor Therapy: Biomarkers and Possibilities for Targeted Therapy with Natural Products
- Naphthoquinone derivatives as P-glycoprotein inducers in inflammatory bowel disease: 2D monolayers, 3D spheroids, and in vivo models
- Biflavonoids from Ginkgo biloba leaves as a novel anti-atherosclerotic candidate: Inhibition potency and mechanistic analysis
- Flavanols from Tetrapleura tetraptera with cytotoxic activities
- A saponin from astragalus promotes pancreatic ductal organoids differentiation into insulin-producing cells
- Protein Expression Profiling and Virtual Drug Screening as an Approach for Individualized Therapy of Small Cell Vaginal Carcinoma
- Onset of p53/NF-κB signaling crosstalk in human melanoma cells in response to anti-cancer theabrownin
- Drug targets and resistance mechanisms in multiple myeloma
- Modulation of Intestinal Corticotropin-Releasing Hormone Signaling by the Herbal Preparation STW 5-II: Possible Mechanisms for Irritable Bowel Syndrome Management
- Lessons from COVID-19 to increase opioid vaccine acceptance
- A Multicenter, Single-Blind, Case-Control, Immunohistochemical Study of Orbital Tissue in Thyroid Eye Disease
- Targeting Angiogenesis By Phytochemicals
- Editorial: II Bio.natural-bioactive natural products research meeting: Pharmacology perspectives
- Novel Class of Proteasome Inhibitors: In Silico and In Vitro Evaluation of Diverse Chloro(trifluoromethyl)aziridines
- Plant extracts and compounds for combating schistosomiasis
- Network Pharmacology of Ginseng (Part III): Antitumor Potential of a Fixed Combination of Red Ginseng and Red Sage as Determined by Transcriptomics
- Parvifloron D-based potential therapy for glioblastoma: Inducing apoptosis via the mitochondria dependent pathway
- Biomarker Expression Profiling in Cervix Carcinoma Biopsies Unravels WT1 as a Target of Artesunate
- Chemometric discrimination of Hylocereus undulatus from different geographical origins via their metabolic profiling and antidiabetic activity
- Can Essential Oils Provide an Alternative Adjuvant Therapy for COVID-19 Infections and Pain Management at the Same Time?
- Antileishmanial Activities of Medicinal Herbs and Phytochemicals In Vitro and In Vivo: An Update for the Years 2015 to 2021
- Current research in biotechnology: Exploring the biotech forefront
- A Comparative Evaluation of the Antimicrobial Activities of the Essential Oils of Three Salvia Species Growing in Egypt, Obtained by Hydrodistillation and Microwave-Assisted Hydro-distillation
- Feature-Based Molecular Networking for the Exploration of the Metabolome Diversity of Common Egyptian Centaurea Species in Relation to Their Cytotoxic Activity
- Identification of Prognostic and Predictive Biomarkers and Druggable Targets among 205 Antioxidant Genes in 21 Different Tumor Types via Data-Mining
- Cytotoxicity of the methanol extracts and compounds of Brucea antidysenterica (Simaroubaceae) towards multifactorial drug-resistant human cancer cell lines
- Phytochemistry, structural diversity, biological activities and pharmacokinetics of iridoids isolated from various genera of the family Scrophulariaceae Juss.
- Network Pharmacology of Triptolide in Cancer Cells: Implications for Transcription Factor Binding
- Modulatory Activity of the Copper Chelate, Copper N-(2-Hydroxy Acetophenone) Glycinate, in ABC-transporter-expressing Cell Lines
- Evidence and rational based research on chinese drugs
- Phytochemical screening of medicinal plants of the Kakamega Country, Kenya commonly used against Cancer
- Targeting Angiogenesis by Therapeutic Antibodies
- Tanshinone Diterpenes: Chemistry and Multifunctional Biological Activities
- In Vitro and In Silico Studies of Two 1, 4-Naphthoquinones and Their Topical Formulation in Bigels
- Therapeutic targeting of SNAIL, RKIP, and YY1 in tumor metastasis and drug resistance
- Integration of Phytochemicals and Phytotherapy into Cancer Precision Medicine
- Mitosis Inhibitors and Medicinal Plants: Neurotoxicity and Neuroprotection
- Identification of chemosensitizers by drug repurposing to enhance the efficacy of cancer therapy
- Anticancer Activity of Salvia miltiorrhiza and Its Secondary Metabolites
- Lernplattformen–entscheidungen mit weitblick
- Inhibition of P-glycoprotein by two artemisinin derivatives
- Activity of artemisinin-type compounds against cancer cells
- Novel developments on Artemisinin and its derivatives for cancer therapy
- Bioactivity of Salvia miltiorrhiza and its constituents
- Teratogenicity and developmental toxicity of herbal products
- Collateral sensitivity in drug-resistant tumor cells
- Adaptogens in chemobrain (part IV): Adaptogenic plants prevent the chemotherapeutics-induced imbalance of redox homeostasis by modulation of expression of genes encoding Nrf2-mediated signaling proteins and antioxidant, metabolizing, detoxifying enzymes in neuroglia cells
- Inverse correlation of epidermal growth factor receptor messenger RNA induction and suppression of anchorage-independent growth by OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in glioblastoma multiforme cell lines
- Quantitative regulation of melanoma growth in the host by tumor-specific serpins in blood serum is a main reason for inefficient tumor treatment
- Growth inhibition of human acute lymphoblastic CCRF-CEM leukemia cells by medicinal plants of the West-Canadian Gwich’in Native Americans
- Herbal Medicines: Boon or Bane for the Human Liver?
- Phytochemical characterization and biological activities of green tea (Camellia sinensis) produced in the Azores, Portugal
- Synthesis, Antibacterial and Cytotoxic Activities of Cyanoenonebenzenesulfonamide, Acetamide and Pyridine-3-carbonitrile Derivatives
- Prognostic and Therapeutic Applications of RKIP in Cancer
- The antimalarial artesunate is also a potent anticancer drug
- 2$\prime$ O-galloylhyperin attenuates LPS-induced acute lung injury via up-regulation antioxidation and inhibition of inflammatory responses in vivo
- Pharmaceutical biology of traditional Chinese medicine for cancer therapy
- High TCTP expression as prognostic factor in different cancer types
- Chemical-biology of natural products from medicinal plants for cancer therapy
- Pharmacogenomics of Biotic and Abiotic Natural Products Derived from Traditional Chinese Medicine for Cancer Therapy
- Activation of Mitochondria-Driven Pathways by Artemisinin and Its Derivatives
- Inhibition of ATP-binding cassette transporters by Chinese herbs and phytochemicals
- Role of nitric oxide for modulation of cancer therapy resistance
- Artemisinin: A versatile weapon from traditional Chinese medicine
- Substanzklassen und Wirkmechanismen
- Self-medication with nutritional supplements and herbal over-thecounter products
- Seminars in cancer biology
- Development of drug resistance in Trichomonas vaginalis and its overcoming with natural products
- Antiviral medicinal herbs and phytochemicals
- Overcoming of P-glycoprotein-mediated multidrug resistance of tumors in vivo by drug combinations
- Expression of the multidrug-resistance gene product P-glycoprotein in gynecological tumors
- Coronaviral ion channels as target for Chinese herbal medicine
- Evaluation of quality of life in patients treated with traditional Chinese medicine
- Ayurveda for cancer treatment
- Expanding the therapeutic spectrum of artemisinin: Activity against infectious diseases beyond malaria and novel pharmaceutical developments
- Artemisinin–second career as anticancer drug?
- Second career for grayanotoxins?
- Medicinal plants and DNA methylation of cancer
- Medicinal and aromatic plant research in the 21st century
- Quality control for medicinal plants
- Polyphenols-Versatile Weapons in Plants and Human Beings
- E-learning in pharmacology and pharmacy
- Perspectives for globalized natural medicines
- Preface: Molecular Approaches of Chinese Medicine
- Therapeutic Intervention of Post-traumatic Stress Disorder by Chinese Medicine: Perspectives for Transdisciplinary Cooperation between Life Sciences and Humanities
- Doctrine of signatures-mystic heritage or outdated relict from middle-aged phytotherapy
- Impact of Plastic-Related Compounds on P-Glycoprotein and Breast Cancer Resistance Protein In Vitro
- Parvifloron D-based therapy for glioblastoma: targeting tumor microenvironment with a natural drug lead
- Anti-inflammatory and epithelial protective effects of herbal preparation STW5-II on mouse intestinal organoids
- Strategies to assess drug interactions in oncology
- The application of TCM to the treatment of psychiatry diseases: in vitro anti-oxidation and anti-inflammatory effect of Free and Easy Wanderer
- Chrysophanol- and nepodin-8-O-β-D-glucopyranoside from Rumex acetosella, the cytotoxicity towards drug sensitive and multi- drug resistant T leukaemia cancer cells
- Chemical characterisation and cytotoxicity evaluation of Convolvulus pluricaulis Sieb. ex Spreng. (Convolvulaceae) extracts towards sensitive and multidrug-resistant cancer cells
- Supporting evidence for the potential usefulness of the herbal preparation STW 5 in an experimental model of Crohn's disease
- Two new genetic mouse models for ulcerative colitis based on lateral tight junction disruption.
- The anti-inflammatory action of the herbal preparation STW5-II in normal human colonic mucosal cells
- Preservation of gastric functional activity in a novel stress model of functional dyspepsia by the herbal preparation, STW5
- Beyond acid insult: TREM-1 signalling and lipid-receptors contribute to the pathogenesis of reflux oesophagitis
- Novel mechanisms underlying the effectiveness of the herbal preparation, STW 5, in functional dyspepsia
- The Eucalyptus oil ingredient 1,8-cineol induces oxidative DNA damage
- Disruption of phosphatidylcholine paracellular movement to intestinal mucus predisposes to Ulcerative Colitis
- Identification of mitochondrial and PI3K-Akt-mTOR pathways as targets of naphtoquinones in cancer cells by pharmacogenomics
- Understanding adaptogens: new evidence on their possible effectiveness in stress-induced and ageing-associated disorders from a DNA microarray study of neuroglia cells
- Artenimol-R in advanced cervical cancer
- Interactions of Chinese medicine with standard treatments
- Modulation of P-glycoprotein, cytochrome P450, and glutathione-S-transferase by resveratrol in human cancer cells
- Digitonin reverses doxorubicin resistance in cancer cells
- Natural products derived from traditional chinese medicine as novel inhibitors of the epidermal growth factor receptor in cancer cells
- The influence of the TCM drug artesunate on the sensitivity of tumor cell lines and his cytotoxic an genotoxic activity
- Genome-scale microRNA identify small RNA modulators of the effect of berberine on pancreatic cancer cell growth
- Effects of dimethylacrylshikonin and epoxyshikonin on melanoma cell lines
- Inhibition of P-glycoprotein, cytochrome P450, and glutathione-S-transferase in human cancer cells by Polygonium cuspidatum
- Approaches for the integration of phytochemicals into classical cancer chemotherapy by modulation of multi-factorial drug resistance
- The TCM drug artesunate induces DNA damage in glioblastoma cells
- Expression profiling and network-based analysis for the effect of curcumin on pancreatic cancer cells
- Thai medicinal plants and the search for new anti-inflammatory and anticancer agents
- A petrol ether extract of Onosma paniculatum Bur. & Franch. shows strong anti-proliferative activity and induces apoptosis in human cancer cell lines
- Inhibition of P-glycoprotein at the blood brain barrier by phytochemicals derived from traditional Chinese medicine
- Workshops for Young Researchers: Cell Culture
- From the Bench to the Bedside: How Natural Products Can Find Their Way
- Anticancer, NF-κB inhibitory and antioxidant properties of Thai traditional anti-inflammatory plants
- Anti-leukemic activity-guided fractionation of Mammea siamensis flowers
- Molecular interactions of artemisinin with DNA and specific target proteins in cancer cells
- Artesunate mediates growth inhibitory effects in human pancreatic cancer cells through modulation of multiple signalling pathways
- Anti-inflammatory and anti-oxidant activity of six Cistus species
- Grayanotoxin III shows microtubule-targeted activity
- In vitro cytotoxicity and p-glycoprotein modulating effects of geranylated furocournarins from Tetradium daniellii
- Molecular mechanism of action of stilbene compounds from Cajanus cajan leaves in cancer cell lines
- Anti-inflammatory and anti-leukemic activities of the flower extracts from Thai medicinal plants
- Molecular mechanism of action of the flavanone pinostrobin from Cajanus cajan leaves in cancer cells
- From molecular diagnostics to molecular targeted therapy with natural product small molecule inhibitors in oral squamous cell carcinoma
- Artesunate as a potent anti-CMV agent in a patient after mismatched haematopietic cell transplantation
- Artemisinin derivatives induce generation of nitric oxide and reactive oxygen species in cell lines of hematopoietic origin
- In silica screening and experimental validation of novel inhibitors of nitric oxide from a database of natural products derived from traditional chinese medicine
- Stilbenes from Cajanus cajan engage apoptotic signals in acute human T-lymphoblastic leukaemia cell lines
- Additive antiviral effect of artemisinin and ribavirin on an "in vitro" model of hepatitis C infection
- Inhibition of tumor angiogenesis in vitro and in vivo by the anti-malarial artesunate
- Expression profiling of ATP-binding cassette (ABC) transporter genes by a low density microarray to detect drug resistance of tumors
- ABCChips as new diagnostic tool to monitoring multidrug resistance in human tumor cells to chemotherapeutics agents by expression profiling of ATP-binding cassette transporter genes.
- Expression profiling of ABC-transporters in childhood AML reveals ABCA3 as a potential cause of drug resistance.
- Biological activity of plant extracts in medullary thyroid carcinoma
- Molecular modes of action of antimalarial artemisinin derivatives as novel anticancer drugs
- The antimalarial artesunate acts also as a potent anticancer drug via both p53-dependent and -independent pathways
- Molecular Modes of Action of an Aqueous Nerium oleander Extract in Cancer Cells In Vitro and In Vivo
- The Novel Artemisinin Dimer Isoniazide ELI-XXIII-98-2 Induces c-MYC Inhibition, DNA Damage, and Autophagy in Leukemia Cells
- Modes of Action of a Novel c-MYC Inhibiting 1,2,4-Oxadiazole Derivative in Leukemia and Breast Cancer Cells
- A whole-genome scan for Artemisinin cytotoxicity reveals a novel therapy for human brain tumors
- The antiviral activities of artemisinin and artesunate
- Leishmaniasis: Drug resistance and natural products (Review)
- Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo
- The Impact of Artificial Intelligence on Traditional Chinese Medicine
- Cytotoxic phytochemicals from the crude extract of Tetrapleura tetraptera fruits towards multi-factorial drug resistant cancer cells
- Cytotoxic and chemotaxonomic study of isolated metabolites fromCentaurea aegyptiaca
- Artesunate as a potent antiviral agent in a patient with late drug-resistant cytomegalovirus infection after hematopoietic stem cell transplantation
- Molecular docking-based virtual drug screening revealing an oxofluorenyl benzamide and a bromonaphthalene sulfonamido hydroxybenzoic acid as HDAC6 inhibitors with cytotoxicity against leukemia cells
- Cytotoxicity of a naturally occuring spirostanol saponin, progenin III, towards a broad range of cancer cell lines by induction of apoptosis, autophagy and necroptosis
- Nanocarriers to enhance solubility, bioavailability, and efficacy of artemisinins
- Organophosphate ester tri-o-cresyl phosphate interacts with estrogen receptor α in MCF-7 breast cancer cells promoting cancer growth
- Novel secondary metabolites from endophytic fungi: synthesis and biological properties
- Collateral sensitivity of natural products in drug-resistant cancer cells
- Cytotoxicity of the crude extract and constituents of the bark of Fagara tessmannii towards multi-factorial drug resistant cancer cells
- A selective inhibitor of the Polo-box domain of Polo-like kinase 1 identified by virtual screening
- Cytotoxicity of fagaramide derivative and canthin-6-one from Zanthoxylum (Rutaceae) species against multidrug resistant leukemia cells
- Cytotoxicity of cucurbitacin E from Citrullus colocynthis against multidrug-resistant cancer cells
- Hepatoprotective and anti-inflammatory effects of total flavonoids of Qu Zhi Ke (peel of Citrus changshan-huyou) on non-alcoholic fatty liver disease in rats via modulation of NF-κB and MAPKs
- The pharmacology of the genus Sophora (Fabaceae): An updated review
- Euphosantianane A-D: Antiproliferative Premyrsinane Diterpenoids from the Endemic Egyptian Plant Euphorbia Sanctae-Catharinae
- Pharmacogenomic Characterization and Isobologram Analysis of the Combination of Ascorbic Acid and Curcumin-Two Main Metabolites of Curcuma longa-in cancer Cells
- Cytotoxicity of methanol extracts of 10 Cameroonian medicinal plants towards multi-factorial drug-resistant cancer cell lines
- Cytotoxicity of 18 Cameroonian medicinal plants against drug sensitive and multi-factorial drug resistant cancer cells
- Multiple resistance to carcinogens and xenobiotics: P-glycoproteins as universal detoxifiers
- Antiproliferative activity against leukemia cells of sesquiterpene lactones from the Turkish endemic plant Centaurea drabifolia subsp detonsa
- Ginkgolic acids inhibit migration in breast cancer cells by inhibition of NEMO sumoylation and NF-κB activity
- Reversal of multidrug resistance by Marsdenia tenacissima and its main active ingredients polyoxypregnanes
- Cytotoxic benzylbenzofuran derivatives from Dorstenia kameruniana
- P-glycoprotein and its inhibition in tumors by phytochemicals derived from Chinese herbs
- Cytotoxicity of compounds from Xylopia aethiopica towards multi-factorial drug-resistant cancer cells
- Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells
- Anti-leukemia activity of semi-synthetic phenolic derivatives from Polygonum limbatum Meisn
- Cytotoxicity and modes of action of 4′-hydroxy-2′,6′-dimethoxychalcone and other flavonoids toward drug-sensitive and multidrug-resistant cancer cell lines
- Phytochemical Analysis and Cytotoxicity Towards Multidrug-Resistant Leukemia Cells of Essential Oils Derived from Lebanese Medicinal Plants
- Aqueous enzymatic process assisted by microwave extraction of oil from yellow horn (Xanthoceras sorbifolia Bunge.) seed kernels and its quality evaluation
- Dryofragin, a phloroglucinol derivative, induces apoptosis in human breast cancer MCF-7 cells through ROS-mediated mitochondrial pathway
- Stem Cells, Cancer Stem-Like Cells, and Natural Products
- Antibacterial Activity and Anticancer Activity of Rosmarinus officinalis L. Essential Oil Compared to That of Its Main Components
- Cytotoxicity and Mode of Action of Four Naturally Occuring Flavonoids from the Genus Dorstenia: Gancaonin Q, 4-Hydroxylonchocarpin, 6-Prenylapigenin, and 6,8-Diprenyleriodictyol
- Cytotoxic flavonoids and isoflavonoids from Erythrina sigmoidea towards multi-factorial drug resistant cancer cells
- Activity of three cytotoxic isoflavonoids from Erythrina excelsa and Erythrina senegalensis (neobavaisoflavone, sigmoidin H and isoneorautenol) toward multi-factorial drug resistant cancer cells
- Cytotoxicity and modes of action of three naturally occurring xanthones (8-hydroxycudraxanthone G, morusignin I and cudraxanthone I) against sensitive and multidrug-resistant cancer cell lines
- A conceptually new treatment approach for relapsed glioblastoma: Coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care.
- Cytotoxicity of some Cameroonian spices and selected medicinal plant extracts
- Artesunate Activates Mitochondrial Apoptosis in Breast Cancer Cells via Iron-catalyzed Lysosomal Reactive Oxygen Species Production
- Cajanol Inhibits the Growth of Escherichia coli and Staphylococcus aureus by Acting on Membrane and DNA Damage
- Cytotoxic Compounds from the Fruits of Uapaca togoensis towards Multifactorial Drug-Resistant Cancer Cells
- Anticancer activities of six selected natural compounds of some Cameroonian medicinal plants
- Combination treatment of malignant B cells using the anti-CD20 antibody rituximab and the anti-malarial artesunate
- Molecular principles of cancer invasion and metastasis (Review)
- Simultaneous determination of main taxoids in Taxus needles extracts by solid-phase extraction-high-performance liquid chromatography with pentafluorophenyl column
- Cajanol, a novel anticancer agent from Pigeonpea [Cajanus cajan (L.) Millsp.] roots, induces apoptosis in human breast cancer cells through a ROS-mediated mitochondrial pathway
- Traditionally used Thai medicinal plants: In vitro anti-inflammatory, anticancer and antioxidant activities
- Antioxidant Activities and Xanthine Oxidase Inhibitory Effects of Extracts and Main Polyphenolic Compounds Obtained from Geranium sibiricum L.
- Supercritical carbon dioxide extraction of seed oil from yellow horn (Xanthoceras sorbifolia Bunge.) and its anti-oxidant activity
- Chemical composition and biological activities of Artemisia judaica essential oil from southern desert of Jordan
- Artemisia herba-alba essential oil from Buseirah (South Jordan): Chemical characterization and assessment of safe antifungal and anti-inflammatory doses
- Signal Transduction Pathways of the Epidermal Growth Factor Receptor in Colorectal Cancer and their Inhibition by Small Molecules
- Artificial intelligence-directed acupuncture: a review
- Identification of Gedunin from a Phytochemical Depository as a Novel Multidrug Resistance-Bypassing Tubulin Inhibitor of Cancer Cells
- Expression of Chemoresistance-Associated ABC Proteins in Hepatobiliary, Pancreatic and Gastrointestinal Cancers
- Expression of the Stem Cell Marker ABCB5 in Normal and Tumor Tissues
- Seed oil of Rosa roxburghii Tratt against non-alcoholic fatty liver disease in vivo and in vitro through PPARα/PGC-1α-mediated mitochondrial oxidative metabolism
- Antileukemia Activity and Mechanism of Platinum(II)-Based Metal Complexes
- Disruption of Lipid Raft Microdomains, Regulation of CD38, TP53, and MYC Signaling, and Induction of Apoptosis by Lomitapide in Multiple Myeloma Cells
- Medicinal Chemistry of Paclitaxel and its Analogues
- Induction of apoptosis, depletion of glutathione, and DNA damage by extracorporeal photochemotherapy and psoralen with exposure to UV light in vitro
- p53 expression in Wilms' tumor:: A possible role as prognostic factor
- In Silico, In Vitro, and In Vivo Investigations on Adapalene as Repurposed Third Generation Retinoid against Multiple Myeloma and Leukemia
- Health(care) in the Crisis: Reflections in Science and Society on Opioid Addiction
- First Nations Healing: From Traditional Medicine to Experimental Ethnopharmacology
- Mbandakamine-Type Naphthylisoquinoline Dimers and Related Alkaloids from the Central African Liana Ancistrocladus ealaensis with Antiparasitic and Antileukemic Activities
- Molecular Determinants of Sensitivity or Resistance of Cancer Cells Toward Sanguinarine
- Medicinal Plants from Near East for Cancer Therapy
- Ancistrolikokine I and further 5,8′-coupled naphthylisoquinoline alkaloids from the Congolese liana Ancistrocladus likoko and their cytotoxic activities against drug-sensitive and multidrug resistant human leukemia cells
- Theabrownin triggers DNA damage to suppress human osteosarcoma U2OS cells by activating p53 signalling pathway
- Prevention from radiation damage by natural products
- Inhibition of human monoamine oxidase A and B by flavonoids isolated from two Algerian medicinal plants
- Genetic Mouse Models with Intestinal-Specific Tight Junction Deletion Resemble an Ulcerative Colitis Phenotype
- Review of current and "omics" methods for assessing the toxicity (genotoxicity, teratogenicity and nephrotoxicity) of herbal medicines and mushrooms
- Cameroonian medicinal plants: pharmacology and derived natural products
- Efficient extraction and preparative separation of four main isoflavonoids from Dalbergia odorifera T. Chen leaves by deep eutectic solvents-based negative pressure cavitation extraction followed by macroporous resin column chromatography
- Cytotoxicity of methanol extracts of Annona muricata, Passiflora edulis and nine other Cameroonian medicinal plants towards multi-factorial drug-resistant cancer cell lines
- Immunogenicity of mammary tumor cells can be induced by shikonin via direct binding-interference with hnRNPA1
- Molecular mechanisms of rosmarinic acid from Salvia miltiorrhiza in acute lymphoblastic leukemia cells
- GPR84 and TREM-1 Signaling Contribute to the Pathogenesis of Reflux Esophagitis
- Kaempferol Derivatives as Antiviral Drugs against the 3a Channel Protein of Coronavirus
- Cytotoxicity, mode of action and antibacterial activities of selected Saudi Arabian medicinal plants
- A radiosensitizing effect of artesunate in glioblastoma cells is associated with a diminished expression of the inhibitor of apoptosis protein survivin
- Characterization of Five Fungal Endophytes Producing Cajaninstilbene Acid Isolated from Pigeon Pea [Cajanus cajan (L.) Millsp.]
- Nobel Prize for artemisinin brings phytotherapy into the spotlight
- Cytotoxicity of three naturally occurring flavonoid derived compounds (artocarpesin, cycloartocarpesin and isobavachalcone) towards multi-factorial drug-resistant cancer cells
- Toxicities by Herbal Medicines with Emphasis to Traditional Chinese Medicine
- Chemical Composition and Antiproliferative Activity of Essential Oil from the Leaves of a Medicinal Herb, Levisticum officinale, against UMSCC1 Head and Neck Squamous Carcinoma Cells
- Cytotoxicity of Thymus vulgaris Essential Oil Towards Human Oral Cavity Squamous Cell Carcinoma
- Complex Interactions between Phytochemicals. The Multi-Target Therapeutic Concept of Phytotherapy
- Anti-Infectious Bronchitis Virus (IBV) Activity of 1,8-cineole: Effect on Nucleocapsid (N) Protein
- Ursolic acid enhances stress resistance, reduces ROS accumulation and prolongs life span in C. elegans serotonin-deficient mutants
- Cytotoxicity of sesquiterpene alkaloids from Nuphar plants toward sensitive and drug-resistant cell lines
- The prophylactic effect of a Eugenia aquea extract against oxidative stress and inflammation associated with the development of arthritis in an adjuvant-induced arthritis rat model
- The protective role of Ocimum basilicum L. (Basil) against aspirin-induced gastric ulcer in mice: Impact on oxidative stress, inflammation, motor deficits and anxiety-like behavior
- Ancistrocyclinones A and B, unprecedented pentacyclic N,C-coupled naphthylisoquinoline alkaloids, from the Chinese liana Ancistrocladus tectorius
- Chemoresistance and chemosensitization in cholangiocarcinoma
- An effective negative pressure cavitation-microwave assisted extraction for determination of phenolic compounds in P. calliantha H. Andr.
- Bioinformatic and experimental fishing for artemisinin-interacting proteins from human nasopharyngeal cancer cells
- Isopetasin and S-isopetasin as novel P-glycoprotein inhibitors against multidrug-resistant cancer cells
- SERCA and P-glycoprotein inhibition and ATP depletion are necessary for celastrol-induced autophagic cell death and collateral sensitivity in multidrug-resistant tumor cells
- Repurposing of plant alkaloids for cancer therapy: Pharmacology and toxicology
- The alkaloid, soyauxinium chloride, displays remarkable cytotoxic effects towards a panel of cancer cells, inducing apoptosis, ferroptosis and necroptosis
- Target Identification of Active Constituents of Shen Qi Wan to Treat Kidney Yang Deficiency Using Computational Target Fishing and Network Pharmacology
- Cytotoxicity of ungeremine towards multi-factorial drug resistant cancer cells and induction of apoptosis, ferroptosis, necroptosis and autophagy
- Cytotoxicity of selected Cameroonian medicinal plants and Nauclea pobeguinii towards multi-factorial drug-resistant cancer cells
- Cytotoxicity of two naturally occurring flavonoids (dorsmanin F and poinsettifolin B) towards multi-factorial drug-resistant cancer cells
- Cytochrome P450 reaction phenotyping and inhibition and induction studies of pinostrobin in human liver microsomes and hepatocytes
- Cytotoxicity of seven naturally occurring phenolic compounds towards multi-factorial drug-resistant cancer cells
- Phytochemical and pharmacological properties of essential oils from Cedrus species
- A Survey of Chinese Medicinal Herbal Treatment for Chemotherapy-Induced Oral Mucositis
- Daedalea gibbosa substances inhibit LPS-induced expression of NOS by suppression of NF-κB and MAPK activities in RAW 264.7 macrophage cells
- Activities of Ten Essential Oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 Cancer Cells
- Effects of artesunate on cytokinesis and G₂/M cell cycle progression of tumour cells and budding yeast.
- Role of antioxidant genes for the activity of artesunate against tumor cells
- Prediction of broad spectrum resistance of tumors towards anticancer drugs
- Evidence-based Chinese medicine for cancer therapy
- Investigation of antibacterial activity of rosemary essential oil against propionibacterium acnes with atomic force microscopy
- Prediction of Drug Sensitivity and Resistance of Cancer by Protein Expression Profiling.
- Sarcoehrenbergilides D-F: cytotoxic cembrene diterpenoids from the soft coral Sarcophyton ehrenbergi
- Synthesis and in vitro biological evaluation of novel diaminothiophene scaffolds as antitumor and antiinfluenza virus agents. Part
- Network Pharmacology of Adaptogens in the Assessment of Their Pleiotropic Therapeutic Activity
- Cytotoxicity, acute and sub-chronic toxicities of the fruit extract of Tetrapleura tetraptera (Schumm. & Thonn.) Taub. (Fabaceae)
- Biomarker Profiling Revealed Carcinoembryonic Antigen as a Target of Artesunate in a Ductal Breast Cancer Patient
- Phytochemicals with activity against methicillin-resistant Staphylococcus aureus
- Role of medicinal plants in inhibiting SARS-CoV-2 and in the management of post-COVID-19 complications
- Rethinking Subthreshold Effects in Regulatory Chemical Risk Assessments
- Aucubin as a natural potential anti-acute hepatitis candidate: Inhibitory potency and hepatoprotective mechanism
- Phytochemical Study and Antiglioblastoma Activity Assessment of Plectranthus hadiensis (Forssk.) Schweinf. ex Sprenger var. hadiensis Stems
- In Silico and In Vitro Screening of 50 Curcumin Compounds as EGFR and NF-κB Inhibitors
- Chemistry and the Potential Antiviral, Anticancer, and Anti-Inflammatory Activities of Cardiotonic Steroids Derived from Toads
- Growth factors-based beneficial effects of platelet lysate on umbilical cord-derived stem cells and their synergistic use in osteoarthritis treatment
- Blue Biotechnology: Computational Screening of Sarcophyton Cembranoid Diterpenes for SARS-CoV-2 Main Protease Inhibition
- Traditional Chinese herbal medicine at the forefront battle against COVID-19: Clinical experience and scientific basis
- Cytotoxicity of apigenin toward multiple myeloma cell lines and suppression of iNOS and COX-2 expression in STAT1-transfected HEK293 cells
- Artesunate Inhibits Growth of Sunitinib-Resistant Renal Cell Carcinoma Cells through Cell Cycle Arrest and Induction of Ferroptosis
- In silico drug discovery of major metabolites from spices as SARS-CoV-2 main protease inhibitors
- Synthesis and biological evaluation of antimalarial and antileukemic activity of new C-10 modified artemisinin derivatives
- Synthesis, computational docking and biological evaluation of celastrol derivatives as dual inhibitors of SERCA and P-glycoprotein in cancer therapy
- Can eastern wisdom resolve western epidemics? Traditional Chinese medicine therapies and the opioid crisis
- Chemotherapeutic efficacy of curcumin and resveratrol against cancer: Chemoprevention, chemoprotection, drug synergism and clinical pharmacokinetics
- Multi-omics approaches to improve malaria therapy
- Pyrrolizidine alkaloids cause cell cycle and DNA damage repair defects as analyzed by transcriptomics in cytochrome P450 3A4-overexpressing HepG2 clone 9 cells
- Screening for natural and derived bio-active compounds in preclinical and clinical studies: One of the frontlines of fighting the coronaviruses pandemic
- Identification of novel compounds against three targets of SARS CoV-2 coronavirus by combined virtual screening and supervised machine learning
- 2α-Hydroxyalantolactone from Pulicaria undulata: activity against multidrug-resistant tumor cells and modes of action
- Furoquinolines and dihydrooxazole alkaloids with cytotoxic activity from the stem bark of Araliopsis soyauxii
- Enzyme assisted extraction of luteolin and apigenin from pigeonpea [Cajanus cajan (L.) Millsp.] leaves
- Development of drug resistance in Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense.: Treatment of human African trypanosomiasis with natural products (Review)
- From traditional Chinese medicine to rational cancer therapy
- Phytochemical inhibitors of the NLRP3 inflammasome for the treatment of inflammatory diseases
- In Silico Mining of Terpenes from Red-Sea Invertebrates for SARS-CoV-2 Main Protease (Mpro) Inhibitors
- Inhibition of cell migration and induction of apoptosis by a novel class II histone deacetylase inhibitor, MCC2344
- Repurposing old drugs to fight multidrug resistant cancers
- Bisphenolic compounds alter gene expression in MCF-7 cells through interaction with estrogen receptor α
- Antimicrobial activity of clove and rosemary essential oils alone and in combination
- Vitamin K3 chloro derivative (VKT-2) inhibits HDAC6, activates autophagy and apoptosis, and inhibits aggresome formation in hepatocellular carcinoma cells
- Ancistrobreveines A- D and related dehydrogenated naphthylisoquinoline alkaloids with antiproliferative activities against leukemia cells, from the West African liana Ancistrocladus abbreviatus
- Cytotoxicity of 40 Egyptian plant extracts targeting mechanisms of drug-resistant cancer cells
- Collateral Sensitivity of Parthenolide via NF-κB and HIF-α Inhibition and Epigenetic Changes in Drug-Resistant Cancer Cell Lines
- Optimization of fermentation parameters with magnetically immobilized Bacillus natto on Ginkgo seeds and evaluation of bioactivity and safety
- MCC1019, a selective inhibitor of the Polo-box domain of Polo-like kinase 1 as novel, potent anticancer candidate
- Shikonin derivatives for cancer prevention and therapy
- Cancer combination therapies with artemisinin-type drugs
- Integration of phytochemicals and phytotherapy into cancer precision medicine
- Hepatotoxicity by combination treatment of temozolomide, artesunate and Chinese herbs in a glioblastoma multiforme patient: case report review of the literature
- Theabrownin Inhibits Cell Cycle Progression and Tumor Growth of Lung Carcinoma through c-myc-Related Mechanism
- Network pharmacology of cancer: From understanding of complex interactomes to the design of multi-target specific therapeutics from nature
- Cynaropicrin disrupts tubulin and c-Myc-related signaling and induces parthanatos-type cell death in multiple myeloma
- The cardiac glycoside ZINC253504760 induces parthanatos-type cell death and G2/M arrest via downregulation of MEK1/2 phosphorylation in leukemia cells
- Tanshinol suppresses osteosarcoma by specifically inducing apoptosis of U2-OS cells through p53-mediated mechanism
- Antiproliferative Potential of African Medicinal Plants
- Quinones and Benzophenones from the Medicinal Plants of Africa
- Phytochemistry and bioactivities of the main constituents of Polyporus umbellatus (Pers.) Fries
- Identification of active components in Andrographis paniculata targeting on CD81 in esophageal cancer in vitro and in vivo
- Natural medicine HLXL targets multiple pathways of amyloid-mediated neuroinflammation and immune response in treating alzheimer's disease
- Untapping the protective role of carotenoids against respiratory diseases
- Medicinal plants and their secondary metabolites in alleviating knee osteoarthritis: A systematic review
- The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis
- Green tea-derived theabrownin suppresses human non-small cell lung carcinoma in xenograft model through activation of not only p53 signaling but also MAPK/JNK signaling pathway
- Coptis chinensis Franch. exhibits neuroprotective properties against oxidative stress in human neuroblastoma cells
- Synergy and antagonism of active constituents of ADAPT-232 on transcriptional level of metabolic regulation of isolated neuroglial cells
- Determination of paclitaxel and other six taxoids in Taxus species by high-performance liquid chromatography-tandem mass spectrometry
- Molecular determinants of cancer cell sensitivity and resistance towards the sesquiterpene farnesol
- Mechanistic perspectives for 1,2,4-trioxanes in anti-cancer therapy
- Microarray-based detection of multidrug resistance in human tumor cells by expression profiling of ATP-binding cassette transporter genes
- Molecular modes of action of artesunate in tumor cell lines
- IMMUNOHISTOCHEMICAL DETECTION OF THE MULTI-DRUG-RESISTANCE MARKER P-GLYCOPROTEIN IN UTERINE CERVICAL CARCINOMAS AND NORMAL CERVICAL TISSUE
- Trypanosomatid Parasites Causing Neglected Diseases
- The role of copper in drug-resistant murine and human tumors
- Inhibition of angiogenesis in vivo and growth of Kaposi's sarcoma xenograft tumors by the anti-malarial artesunate
- COX2-Inhibitory and Cytotoxic Activities of Phytoconstituents of Matricaria chamomilla L.
- Two palladium (II) complexes derived from halogen-substituted Schiff bases and 2-picolylamine induce parthanatos-type cell death in sensitive and multi-drug resistant CCRF-CEM leukemia cells
- Natural products in drug discovery: Advances and opportunities
- Cajanin stilbene acid: A direct inhibitor of colistin resistance protein MCR-1 that restores the efficacy of polymyxin B against resistant Gram-negative bacteria
- Carotenoids for lung cancer chemoprevention and chemotherapy: Promises and controversies
- Essential oil of Acorus tatarinowii Schott inhibits neuroinflammation by suppressing NLRP3 inflammasome activation in 3 x Tg-AD transgenic mice
- Factors Determining Sensitivity and Resistance of Tumor Cells to Arsenic Trioxide
- Broken dreams or time to test? Chemoselective treatment of MTAP-deficient tumors with L-alanosine
- Cardiotoxicity and Cardioprotection by Artesunate in Larval Zebrafish
- Therapeutic potential of polyphenols in cardiovascular diseases: Regulation of mTOR signaling pathway
- Anti-inflammatory and anti-cancer activities of frankincense: Targets, treatments and toxicities
- The emergence of drug resistance to targeted cancer therapies: Clinical evidence
- Best practice in research - Overcoming common challenges in phytopharmacological research
- Effect of ABC transporter expression and mutational status on survival rates of cancer patients
- Tumor microenvironment and epithelial mesenchymal transition as targets to overcome tumor multidrug resistance
- Shikonin Reduces Growth of Docetaxel-Resistant Prostate Cancer Cells Mainly through Necroptosis
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
- Screening of potent phytochemical inhibitors against SARS-CoV-2 protease and its two Asian mutants
- In Vitro Study of the Cytotoxic, Cytostatic, and Antigenotoxic Profile of Hemidesmus indicus (L.) R.Br. (Apocynaceae) Crude Drug Extract on T Lymphoblastic Cells
- Beyond malaria: The inhibition of viruses by artemisinin-type compounds
- Phytochemicals as inhibitors of NF-κB for treatment of Alzheimer's disease
- A naturally occuring triterpene saponin ardisiacrispin B displayed cytotoxic effects in multi-factorial drug resistant cancer cells via ferroptotic and apoptotic cell death
- The activity of Artemisia spp. and their constituents against Trypanosomiasis
- Synthesis of Thymoquinone-Artemisinin Hybrids: New Potent Antileukemia, Antiviral, and Antimalarial Agents
- Application of integrative cloud point extraction and concentration for the analysis of polyphenols and alkaloids in mulberry leaves
- Repurposing of Bromocriptine for Cancer Therapy
- Novel molecular mechanisms for the adaptogenic effects of herbal extracts on isolated brain cells using systems biology
- Long-term add-on therapy (compassionate use) with oral artesunate in patients with metastatic breast cancer after participating in a phase I study (ARTIC M33/2)
- Resveratrol mediated cancer cell apoptosis, and modulation of multidrug resistance proteins and metabolic enzymes
- MicroRNA targeting by quercetin in cancer treatment and chemoprotection
- Pinolenic acid ameliorates oleic acid-induced lipogenesis and oxidative stress via AMPK/SIRT1 signaling pathway in HepG2 cells
- Development of artemisinin resistance in malaria therapy
- Anti-poliovirus activity of Nerium oleander aqueous extract
- Effects of anti-inflammatory and adaptogenic herbal extracts on gene expression of eicosanoids signaling pathways in isolated brain cells
- African Flora Has the Potential to Fight Multidrug Resistance of Cancer
- Synergy assessment of fixed combinations of Herba Andrographidis and Radix Eleutherococci extracts by transcriptome-wide microarray profiling
- A Randomised, Double Blind, Placebo-Controlled Pilot Study of Oral Artesunate Therapy for Colorectal Cancer
- Cytotoxicity of South-African medicinal plants towards sensitive and multidrug-resistant cancer cells
- Antischistosomal activity of artemisinin derivatives in vivo and in patients
- Pharmacogenetics and Pharmacotherapy of Military Personnel Suffering from Post-traumatic Stress Disorder
- The role of p53 in cancer drug resistance and targeted chemotherapy
- Dioncophyllines C2, D2, and F and Related Naphthylisoquinoline Alkaloids from the Congolese Liana Ancistrocladus ileboensis with Potent Activities against Plasmodium falciparum and against Multiple Myeloma and Leukemia Cell Lines
- Anti-inflammatory Effects of Herbal Preparations STW5 and STW5-II in Cytokine-Challenged Normal Human Colon Cells
- The Combined Effects of Ethylene and MeJA on Metabolic Profiling of Phenolic Compounds in Catharanthus roseus Revealed by Metabolomics Analysis
- Pharmacological and chemical features of Nepeta L. genus: Its importance as a therapeutic agent
- Potential of Central, Eastern and Western Africa Medicinal Plants for Cancer Therapy: Spotlight on Resistant Cells and Molecular Targets
- From ancient herb to modern drug: Artemisia annua and artemisinin for cancer therapy
- Prospective open uncontrolled phase I study to define a well-tolerated dose of oral artesunate as add-on therapy in patients with metastatic breast cancer (ARTIC M33/2)
- Nitensidine A, a guanidine alkaloid from Pterogyne nitens, induces osteoclastic cell death
- Cytotoxicity and modes of action of four Cameroonian dietary spices ethno-medically used to treat Cancers: Echinops giganteus, Xylopia aethiopica, Imperata cylindrica and Piper capense
- Can Medical Herbs Stimulate Regeneration or Neuroprotection and Treat Neuropathic Pain in Chemotherapy-Induced Peripheral Neuropathy?
- Glycyrrhizic acid nanoparticles inhibit LPS-induced inflammatory mediators in 264.7 mouse macrophages compared with unprocessed glycyrrhizic acid
- Mechanisms of Herb-Induced Nephrotoxicity
- Cytotoxicity of four Aframomum species (A. arundinaceum, A. alboviolaceum, A. kayserianum and A. polyanthum) towards multi-factorial drug resistant cancer cell lines
- Identification of cellular and molecular factors determining the response of cancer cells to six ergot alkaloids
- Mechanism of action of Rhodiola, salidroside, tyrosol and triandrin in isolated neuroglial cells: An interactive pathway analysis of the downstream effects using RNA microarray data
- The eucalyptus oil ingredient 1,8-cineol induces oxidative DNA damage
- Activity of the dietary flavonoid, apigenin, against multidrug-resistant tumor cells as determined by pharmacogenomics and molecular docking
- Human cytomegalovirus kinetics following institution of artesunate after hematopoietic stem cell transplantation
- Traditional Chinese medicine research in the post-genomic era: Good practice, priorities, challenges and opportunities
- Effect of artemisinins and other endoperoxides on nitric oxide-related signaling pathway in RAW 264.7 mouse macrophage cells
- Artesunate Induces ROS-Mediated Apoptosis in Doxorubicin-Resistant T Leukemia Cells
- P-GLYCOPROTEIN EXPRESSION IN TREATED AND UNTREATED HUMAN-BREAST CANCER
- N-BENZYLADRIAMYCIN-14-VALERATE VERSUS PROGRESSIVELY DOXORUBICIN-RESISTANT MURINE TUMORS - CELLULAR PHARMACOLOGY AND CHARACTERIZATION OF CROSS-RESISTANCE INVITRO AND INVIVO
- Differentially Tolerized Mouse Antigen Presenting Cells Share a Common miRNA Signature Including Enhanced mmu-miR-223-3p Expression Which Is Sufficient to Imprint a Protolerogenic State
- Xylochemical Synthesis and Biological Evaluation of Shancigusin C and Bletistrin G
- Network pharmacology of triptolide in cancer cells: implications for transcription factor binding
- Activity of Cordycepin From Cordyceps sinensis Against Drug-Resistant Tumor Cells as Determined by Gene Expression and Drug Sensitivity Profiling
- Synergistic inhibition of angiogenesis by artesunate and captopril in vitro and in vivo
- Targeting angiogenesis by phytochemicals
- Interaction of antihistaminic drugs with human translationally controlled tumor protein (TCTP) as novel approach for differentiation therapy
- Cytotoxicity and modes of action of the methanol extracts of six Cameroonian medicinal plants against multidrug-resistant tumor cells
- Identification of Novel Rare ABCC1 Transporter Mutations in Tumor Biopsies of Cancer Patients
- Chemometric and Transcriptomic Profiling, Microtubule Disruption and Cell Death Induction by Secalonic Acid in Tumor Cells
- Synthesis and biological evaluation of a D-ring-contracted analogue of lamellarin D
- Nimbolide inhibits 2D and 3D prostate cancer cells migration, affects microtubules and angiogenesis and suppresses B-RAF/p.ERK-mediated in vivo tumor growth
- The intestinal 3M (microbiota, metabolism, metabolome) zeitgeist-from fundamentals to future challenges
- Phytomedicine mourns the death of its founding editor Professor Hildebert Wagner
- The Chinese herbal formula Free and Easy Wanderer ameliorates oxidative stress through KEAP1-NRF2/HO-1 pathway
- Identification of Phlogacantholide C as a Novel ADAM10 Enhancer from Traditional Chinese Medicinal Plants
- Cytotoxicity of Salvia miltiorrhiza Against Multidrug-Resistant Cancer Cells
- Extract of Caragana sinica as a potential therapeutic option for increasing alpha-secretase gene expression
- Evaluating ancient Egyptian prescriptions today : anti-inflammatory activity of Ziziphus spina-christi
- Paeonia lactiflora Pall. ameliorates acetaminophen-induced oxidative stress and apoptosis via inhibiting the PKC-ERK pathway
- A drug repurposing approach for individualized cancer therapy based on transcriptome sequencing and virtual drug screening
- A novel moniliformin derivative as pan-inhibitor of histone deacetylases triggering apoptosis of leukemia cells
- Repurposing of artemisinin-type drugs for the treatment of acute leukemia
- Cytotoxicity and antimitotic activity of Rhinella schneideri and Rhinella marina venoms
- Natural products targeting tumour angiogenesis
- Novel artemisinin derivative FO8643 with anti-angiogenic activity inhibits growth and migration of cancer cells via VEGFR2 signaling
- Anti-Inflammatory Effect of a TCM Formula Li-Ru-Kang in Rats With Hyperplasia of Mammary Gland and the Underlying Biological Mechanisms
- Clinical Efficacy and Safety of Xinmailong Injection for the Treatment of Chronic Heart Failure: A Meta-Analysis
- Hepatoprotective Effect of San-Cao Granule on Con A-Induced Liver Injury in Mice and Mechanisms of Action Exploration
- Zingiberis rhizoma mediated enhancement of the pharmacological effect of aconiti lateralis radix praeparata against acute heart failure and the underlying biological mechanisms
- The protective effects of compatibility of Aconiti Lateralis Radix Praeparata and Zingiberis Rhizoma on rats with heart failure by enhancing mitochondrial biogenesis via Sirt1/PGC-1α pathway
- Evaluation of the Antibacterial Effects of Flavonoid Combination from the Leaves of Dracontomelon dao by Microcalorimetry and the Quadratic Rotary Combination Design
- Therapeutic efficacy and safety of Shexiang Baoxin Pill combined with trimetazidine in elderly patients with heart failure secondary to ischaemic cardiomyopathy
- Network Pharmacology of Angiogenesis Inhibitors Inspired by Nature
- Artemisinin derivative FO-ARS-123 as a novel VEGFR2 inhibitor suppresses angiogenesis and cell migration
- Artemisinin Derivative FO-ARS-123 as a Novel VEGFR2 Inhibitor Suppresses Angiogenesis, Cell Migration, and Invasion
- A novel moniliformin derivative as pan-inhibitor of histone deacetylases triggering apoptosis of leukemia cells
- Artemisinin derivative FO-ARS-123 as a novel VEGFR2 inhibitor suppresses angiogenesis, cell migration, and invasion
- Potential Coronaviral Inhibitors of the Nucleocapsid Protein Identified In Silico and In Vitro from a Large Natural Product Library
- Coronavirus Inhibitors Targeting nsp16
- Shikonin Directly Targets Mitochondria and Causes Mitochondrial Dysfunction in Cancer Cells
- Cytotoxicity, anti-angiogenic, apoptotic effects and transcript profiling of a naturally occurring naphthyl butenone, Guieranone A
- Molecular biology of cantharidin in cancer cells
- Development of resistance towards artesunate in mda-mb-231 human breast cancer cells
- Identification of potential novel drug resistance mechanisms by genomic and transcriptomic profiling of colon cancer cells with p53 deletion
- Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress- and aging-related diseases
- Cytotoxicity of Crude Extract and Isolated Constituents of the Dichrostachys cinerea Bark towards Multifactorial Drug-Resistant Cancer Cells
- Identification of inhibitors of the polo-box domain of polo-like kinase 1 from natural and semisynthetic compounds
- Vitamin K3 thio-derivative: a novel specific apoptotic inducer in the doxorubicin-sensitive and -resistant cancer cells
- Nanoscale delivery of phytochemicals targeting CRISPR/Cas9 for cancer therapy
- Synthesis and Cytotoxicity of Diarylpentanoids against Sensitive CCRF-CEM and Multidrug-Resistant CEM/ADR5000 Leukemia Cells
- Network Pharmacology of Red Ginseng (Part I): Effects of Ginsenoside Rg5 at Physiological and Sub-Physiological Concentrations
- Epigenetic Alterations Upstream and Downstream of p53 Signaling in Colorectal Carcinoma
- Dietary polyphenols in chemoprevention and synergistic effect in cancer: Clinical evidences and molecular mechanisms of action
- Cytotoxicity and modes of action of four naturally occuring Benzophenones : 2,2',5,6'-tetrahydroxybenzophenone, guttiferone E, isogarcinol and isoxanthochymol
- Ethnopharmacology, phytochemistry, chemical ecology and invasion biology of Acanthus mollis L.
- Repurposing of the ALK Inhibitor Crizotinib for Acute Leukemia and Multiple Myeloma Cells
- The immunosuppressive activity of artemisinin-type drugs towards inflammatory and autoimmune diseases
- Identification and characterization of deschloro-chlorothricin obtained from a large natural product library targeting aurora A kinase in multiple myeloma (vol 39, pg 348, 2021)
- Selection of safe artemisinin derivatives using a machine learning-based cardiotoxicity platform and in vitro and in vivo validation
- Identification and characterization of deschloro-chlorothricin obtained from a large natural product library targeting aurora A kinase in multiple myeloma
- A novel ligand of the translationally controlled tumor protein (TCTP) identified by virtual drug screening for cancer differentiation therapy
- Biopiracy versus One-World Medicine-From colonial relicts to global collaborative concepts
- Broken heart, tako-tsubo or stress cardiomyopathy? Metaphors, meanings and their medical impact
- Biopiracy of natural products and good bioprospecting practice
- Prediction of cancer drug resistance and implications for personalized medicine
- Network Pharmacology of Red Ginseng (Part I): Effects of Ginsenoside Rg5 at Physiological and Sub-Physiological Concentrations
- Green Tea-Derived Theabrownin Induces Cellular Senescence and Apoptosis of Hepatocellular Carcinoma via P53 Signaling-Mediated Mechanism Bypassed by JNK Regulation
- Dendrobium officinale Polysaccharide Alleviates Intestinal Inflammation by Promoting Small Extracellular Vesicle Packaging of miR-433-3p
- Cardioprotective effects of phytopigments via multiple signaling pathways
- Network Pharmacology of Ginseng (Part II): The Differential Effects of Red Ginseng and Ginsenoside Rg5 in Cancer and Heart Diseases as Determined by Transcriptomics
- Suppression of colorectal carcinogenesis by naringin
- Kinome-Wide Profiling Identifies Human WNK3 as a Target of Cajanin Stilbene Acid from Cajanus cajan (L.) Millsp.
- Network Pharmacology of Ginseng (Part II): The Differential Effects of Red Ginseng and Ginsenoside Rg5 in Cancer and Heart Diseases as Determined by Transcriptomics
- Cytotoxicity of 4-hydroxy-N-(naphthalen-1-yl)-2-oxo-2H-chromene-3-car-boxamide in multidrug-resistant cancer cells through activation of PERK/eIF2α/ATF4 pathway
- The neuroprotective potential of carotenoids in vitro and in vivo
- Green tea-derived theabrownin induces cellular senescence and apoptosis of hepatocellular carcinoma through p53 signaling activation and bypassed JNK signaling suppression
- Fungal Biofilms as a Valuable Target for the Discovery of Natural Products That Cope with the Resistance of Medically Important Fungi-Latest Findings
- Identification of Novel Anthracycline Resistance Genes and Their Inhibitors
- Inhibition of c-MYC with involvement of ERK/JNK/MAPK and AKT pathways as a novel mechanism for shikonin and its derivatives in killing leukemia cells
- Transport processes of radiopharmaceuticals and -modulators
- Effect of Extraction Methodology on the Phytochemical Composition for Camelia sinensis "Powdered Tea Extracts" from Different Provenances
- Jozimine A2, a Dimeric Naphthylisoquinoline (NIQ) Alkaloid, Shows In Vitro Cytotoxic Effects against Leukemia Cells through NF-κB Inhibition
- Botanical hybrid preparations (BHP) in phytomedicine and phytotherapy research: background and perspectives
- Advances in antitumor activity and mechanism of natural steroidal saponins: A review of advances, challenges, and future prospects
- Molecular networking-guided investigation of the secondary metabolome of four Morus species and their in vivo neuroprotective potential for the mitigation of Alzheimer's disease
- State-of-the-Art Review on Botanical Hybrid Preparations in Phytomedicine and Phytotherapy Research: Background and Perspectives
- Molecular insights into experimental models and therapeutics for cholestasis
- Optimized therapeutic potential of Yinchenhao decoction for cholestatic hepatitis by combined network meta-analysis and network pharmacology
- SIRT1-activating butein inhibits arecoline-induced mitochondrial dysfunction through PGC1α and MTP18 in oral cancer
- Anticancer diterpenes of African natural products: Mechanistic pathways and preclinical developments
- Impact of plastic-related compounds on the gene expression signature of HepG2 cells transfected with CYP3A4
- Identification of Antagonistic Action of Pyrrolizidine Alkaloids in Muscarinic Acetylcholine Receptor M1 by Computational Target Prediction Analysis
- Lignan contents of Schisandra chinensis (Turcz.) Baill. from different origins—A new model for evaluating the content of prominent components of Chinese herbs
- Obituary: Phytomedicine's Associate Editor Professor Dr. David Yue-Wei Lee has passed away
Besitzt PublikationDie Publikationsliste für die Kategorie "Organisationseinheit" zeigt alle Publikationen, die der einzelnen Organisationseinheit direkt zugeordnet sind. Für eine Liste, die auch alle Publikationen von untergeordneten Organisationseinheiten inkludiert, nutzen Sie die Liste in der Facette "Organisationseinheit".