Author: Abdelfatah, Sara and Efferth, Thomas / Organizational unit: Pharmazeutische Biologie / Data source: Europe PubMed Central - Universitätsbibliographie Search Results

Start Over Author Abdelfatah, Sara Author Efferth, Thomas Organizational unit Pharmazeutische Biologie Data source Europe PubMed Central

1. The triterpenoid ursolic acid ameliorates stress in Caenorhabditis elegans by affecting the depression-associated genes skn-1 and prdx2

Autoren:: Nass, Janine; Abdelfatah, Sara; Efferth, Thomas
Veröffentlichungsdatum:: 2021
Type:: Journal article

2. Pyrrolizidine alkaloids cause cell cycle and DNA damage repair defects as analyzed by transcriptomics in cytochrome P450 3A4-overexpressing HepG2 clone 9 cells

Autoren:: Abdelfatah, Sara; Nass, Janine; Knorz, Caroline; Klauck, Sabine M; Kuepper, Jan-Heiner; Efferth, Thomas
Veröffentlichungsdatum:: 2022
Type:: Journal article

3. Ursolic acid enhances stress resistance, reduces ROS accumulation and prolongs life span in C. elegans serotonin-deficient mutants

Autoren:: Nass, Janine; Abdelfatah, Sara; Efferth, Thomas
Veröffentlichungsdatum:: 2021
Type:: Journal article

4. Induction of stress resistance and extension of lifespan in Chaenorhabditis elegans serotonin-receptor knockout strains by withanolide A

Autoren:: Nass, Janine; Abdelfatah, Sara; Efferth, Thomas
Veröffentlichungsdatum:: 2021
Type:: Journal article

5. The alkaloid, soyauxinium chloride, displays remarkable cytotoxic effects towards a panel of cancer cells, inducing apoptosis, ferroptosis and necroptosis

Autoren:: Mbaveng, Armelle T; Noulala, Cedric GT; Samba, Anne RM; Tankeo, Simplice B; Abdelfatah, Sara; Fotso, Ghislain W; Happi, Emmanuel N; Ngadjui, Bonaventure T; Beng, Veronique P; Kuete, Victor; Efferth, Thomas
Veröffentlichungsdatum:: 2021
Type:: Journal article

6. N-acetylglycoside of oleanolic acid (aridanin) displays promising cytotoxicity towards human and animal cancer cells, inducing apoptotic, ferroptotic and necroptotic cell death

Autoren:: Mbaveng, Armelle T; Chi, Godloves F; Bonsou, Idrios N; Abdelfatah, Sara; Tamfu, Alfred N; Yeboah, Elisabeth MO; Kuete, Victor; Efferth, Thomas
Veröffentlichungsdatum:: 2020
Type:: Journal article

7. 8,8-bis-(Dihydroconiferyl)-diferulate displayed impressive cytotoxicity towards a panel of human and animal cancer cells

Autoren:: Mbaveng, Armelle T; Damen, Francois; Guefack, Michel-Gael F; Tankeo, Simplice Beaudelaire; Abdelfatah, Sara; Bitchagno, Gabin TM; Celik, Ilhami; Kuete, Victor; Efferth, Thomas
Veröffentlichungsdatum:: 2020
Type:: Journal article

8. Isopetasin and S-isopetasin as novel P-glycoprotein inhibitors against multidrug-resistant cancer cells

Autoren:: Abdelfatah, Sara; Boeckers, Madeleine; Asensio, Maitane; Kadioglu, Onat; Klinger, Anette; Fleischer, Edmond; Efferth, Thomas
Veröffentlichungsdatum:: 2021
Type:: Journal article

9. The antioxidant 2,3-dichloro,5,8-dihydroxy,1,4-naphthoquinone inhibits acetyl-cholinesterase activity and amyloid β42 aggregation: A dual target therapeutic candidate compound for the treatment of Alzheimer's disease

Autoren:: Khelifi, Imen; Tourrette, Audrey; Dhouafli, Zohra; Bouajila, Jalloul; Efferth, Thomas; Abdelfatah, Sara; Ksouri, Riadh; Hayouni, El Akrem
Veröffentlichungsdatum:: 2020
Type:: Journal article

10. MCC1019, a selective inhibitor of the Polo-box domain of Polo-like kinase 1 as novel, potent anticancer candidate

Autoren:: Abdelfatah, Sara; Berg, Angela; Huang, Qi; Yang, Li Jun; Hamdoun, Sami; Klinger, Anette; Greten, Henry J; Fleischer, Edmond; Berg, Thorsten; Wong, Vincent KW; Efferth, Thomas
Veröffentlichungsdatum:: 2019
Type:: Journal article