Chromosomenbiologie

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The following list shows all publications with a direct relation to the organisational unit. To retrieve a list which includes publications of subordinate organisational units, use the search facet "Organizational structure".

• Getting in (and out of) the loop: regulating higher order telomere structures
• Telomere regulation
• Role of the ESCRT Complexes in Telomere Biology
• No DDRama at chromosome ends: TRF2 takes centre stage
• Breaking new ground: digging into TERRA function
• The Mph1 helicase can promote telomere uncapping and premature senescence in budding yeast
• Rif2 promotes a telomere fold-back structure through Rpd3L recruitment in budding yeast
• Subtelomeric repetitive elements determine TERRA regulation by Rap1/Rif and Rap1/Sir complexes in yeast
• Mixed Integer Linear Programming based machine learning approach identifies regulators of telomerase in yeast
• High nutrient levels and TORC1 activity reduce cell viability following prolonged telomere dysfunction and cell cycle arrest
• Saccharomyces cerevisiae Ebs1p is a putative ortholog of human Smg7 and promotes nonsense-mediated mRNA decay
• Telomeres and disease: enter TERRA
• Deregulated telomere transcription causes replication-dependent telomere shortening and promotes cellular senescence
• The Replisome-Coupled E3 Ubiquitin Ligase Rtt101Mms22 Counteracts Mrc1 Function to Tolerate Genotoxic Stress
• TERRA: telomeric repeat-containing RNA
• Yeast Uri1p promotes translation initiation and may provide a link to cotranslational quality control
• From \textquotedblCellular\textquotedbl RNA to \textquotedblSmart\textquotedbl RNA: Multiple Roles of RNA in Genome Stability and Beyond
• Exploring Quantitative Yeast Phenomics with Single-Cell Analysis of DNA Damage Foci
• The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae
• FANCM regulates DNA chain elongation and is stabilized by S-phase checkpoint signalling
• The F-box protein Dia2 overcomes replication impedance to promote genome stability in Saccharomyces cerevisiae
• Control of nutrient-sensitive transcription programs by the unconventional prefoldin URI
• The cullin Rtt101p promotes replication fork progression through damaged DNA and natural pause sites
• The PIAS homologue Siz2 regulates perinuclear telomere position and telomerase activity in budding yeast
• Telomeric RNA-DNA hybrids affect telomere-length dynamics and senescence
• Regulatory R-loops as facilitators of gene expression and genome stability
• Molecular and physiological consequences of faulty eukaryotic ribonucleotide excision repair
• Telomerase is essential to alleviate pif1-induced replication stress at telomeres
• The Rat1p 5’ to 3’ exonuclease degrades telomeric repeat-containing RNA and promotes telomere elongation in Saccharomyces cerevisiae
• Mre11-Rad50 oligomerization promotes DNA double-strand break repair
• Non-coding RNAs at the Eukaryotic rDNA Locus: RNA-DNA Hybrids and Beyond
• ClpX stimulates the mitochondrial unfolded protein response (UPRmt) in mammalian cells
• The AB loop and D-helix in binding site III of human Oncostatin M (OSM) are required for OSM receptor activation
• Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNA
• Chromatin modifiers and recombination factors promote a telomere fold-back structure, that is lost during replicative senescence
• Telomere Interacting Proteins and TERRA Regulation
• Nitric Oxide-associated Protein 1 (NOA1) Is Necessary for Oxygen-dependent Regulation of Mitochondrial Respiratory Complexes
• Npl3 stabilizes R-loops at telomeres to prevent accelerated replicative senescence
• The Bidirectional Link Between RNA Cleavage and Polyadenylation and Genome Stability: Recent Insights From a Systematic Screen
• Phosphoproteomics of the developing heart identifies PERM1-An outer mitochondrial membrane protein
• Hypoxic transcription gene profiles under the modulation of nitric oxide in nuclear run on-microarray and proteomics
• Genetic requirements for repair of lesions caused by single genomic ribonucleotides in S phase
• Binding to G-quadruplex RNA activates the mitochondrial GTPase NOA1
• Skeletal Muscle-Specific Methyltransferase METTL21C Trimethylates p97 and Regulates Autophagy-Associated Protein Breakdown
• NOA1, a Novel ClpXP Substrate, Takes an Unexpected Nuclear Detour Prior to Mitochondrial Import
• Noncovalent, site-specific biotinylation of histidine-tagged proteins
• Postnatal cardiomyocyte growth and mitochondrial reorganization cause multiple changes in the proteome of human cardiomyocytes
• PrimPol is required for replication reinitiation after mtDNA damage
• Genetic requirements for repair of lesions caused by single genomic ribonucleotides in S phase
• Telomere Length Determines TERRA and R-Loop Regulation through the Cell Cycle
• Checkpoint adaptation in recombination-deficient cells drives aneuploidy and resistance to genotoxic agents
• Inactivation of folylpolyglutamate synthetase Met7 results in genome instability driven by an increased dUTP/dTTP ratio
• RNA-DNA hybrids prevent resection at dysfunctional telomeres
• DNA-RNA Hybrids at Telomeres in Budding Yeast
• DNA damage repair proteins across the Tree of Life
• TERRA increases at short telomeres in yeast survivors and regulates survivor associated senescence (SAS)
• Increased TERRA levels and RNase H sensitivity are conserved hallmarks of post-senescent survivors in budding yeast
• RNase H1 and H2 Are Differentially Regulated to Process RNA-DNA Hybrids
• Metabolic remodeling maintains a reducing environment for rapid activation of the yeast DNA replication checkpoint
• The Smc5/6 complex regulates the yeast Mph1 helicase at RNA-DNA hybrid-mediated DNA damage
• A subtelomeric region affects telomerase-negative replicative senescence in Saccharomyces cerevisiae
• Transcription of ncRNAs promotes repair of UV induced DNA lesions in Saccharomyces cerevisiae subtelomeres
• R-loop proximity proteomics identifies a role of DDX41 in transcription-associated genomic instability
• Chromatin modifiers and recombination factors promote a telomere fold-back structure, that is lost during replicative senescence
• The differential processing of telomeres in response to increased telomeric transcription and RNA-DNA hybrid accumulation
• A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34+ hematopoietic stem cells not reversible by mTOR-inhibition
• Mte1 interacts with Mph1 and promotes crossover recombination and telomere maintenance
• TERRA and the state of the telomere
• Chromatin modifiers and recombination factors promote a telomere fold-back structure, that is lost during replicative senescence
• Checkpoint adaptation in repair-deficient cells drives aneuploidy and resistance to genotoxic agents
• RNase H1 and H2 are differentially regulated to eliminate RNA-DNA hybrids
• R-loop proximity proteomics identifies a role of DDX41 in transcription-associated genomic instability
• Non-coding RNAs at the Eukaryotic rDNA Locus: RNA-DNA Hybrids and Beyond
• Npl3 stabilizes R-loops at telomeres to prevent accelerated replicative senescence

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• Institut für Entwicklungs- und Neurobiologie