Radiopharmazeutische Chemie
- Beziehungen:
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- Relationship between dopamine D2 receptor occupancy, clinical response, and drug and monoamine metabolites levels in plasma and cerebrospinal fluid. A pilot study in patients suffering from first-episode schizophrenia treated with quetiapine (Retraction of vol 44, pg 754, 2010)
- Radiopharmaceutical Chemistry
- Measurement of Protein Synthesis: In Vitro Comparison of 68 Ga-DOTA-Puromycin,[3 H] Tyrosine, and 2-Fluoro-[3 H] tyrosine
- 339 SMALL ANIMAL PET-IMAGING WITH SCANDIUM-44-DOTATOC
- Kinetic modeling and parametric imaging for human [18F] desmethoxyfallypride dynamic PET studies
- Kinetic analysis of [18F] Desmethoxyfallypride by human dynamic PET
- Assessment of D2-receptor binding using 18F-Fallypride
- Opioidergic system and personality:: Investigations on the neurobiological correlate of personality traits of healthy subjects using [F-18]fluoro-ethyl-diprenorphine positron emission tomography
- NMR Hyperpolarization of established PET tracers
- Small Animal PET-Imaging with Scandium-44-DOTATOC
- 18F-LABELING AND EVALUATION OF NOVEL 18F-LABELED MDL 100907 DERIVATIVES
- Improved automated synthesis of [18F] fluoroethylcholine as a radiotracer for cancer imaging
- Parametric mapping of binding in human brain of D2 receptor ligands of different affinities
- Efficient alkali iodide promoted 18F-fluoroethylations with 2-[18F] fluoroethyl tosylate and 1-bromo-2-[18F] fluoroethane
- Structure Function Evaluation of Imidazopyridine Derivatives Selective for δ-Subunit-Containing γ-Aminobutyric Acid Type A (GABAA) Receptors
- Evaluation of various bifunctional chelators for the synthesis of radiometal-labeled CNS tracers
- MAOA-VNTR polymorphism modulates context-dependent dopamine release and aggressive behavior in males
- No evidence for attenuated stress-induced extrastriatal dopamine signaling in psychotic disorder
- Imaging of Protein Synthesis: In Vitro and In Vivo Evaluation of 44Sc-DOTA-Puromycin
- Synthesis, labelling and evaluation of hydantoin-substituted indole carboxylic acids as potential ligands for positron emission tomography imaging of the glycine binding site of the N-methyl-D-aspartate receptor
- P-Glycoprotein influence on the brain uptake of a 5-HT2A ligand:[18F] MH. MZ
- Synthesis and evaluation of 5, 7-dichloro-4-(3-$$4-[4-(2-[18F] fluoroethyl)-piperazin-1-yl]-phenyl$$-ureido)-1, 2, 3, 4-tetrahydroquinoline-2-carboxylic acid as a potential NMDA ligand to study glutamatergic neurotransmission in vivo
- The DAT ligand [(18) F] PR17. MZ mirrors the in vivo pharmacokinetic profile of [(11) C] cocaine with significantly improved monoamine transporter selectivity
- SYNTHESIS AND RADIOIODINATION OF HALOGENATED BENZAMIDE DERIVATIVES FOR THE NON-INVASIVE VISUALIZATION OF D2-LIKE DOPAMINE RECEPTORS
- SYNTHESIS, LABELLING AND EVALUATION OF A NEW FLUORINATED NMDA LIGAND TO STUDY GLUTAMATERGIC NEUROTRANSMISSION IN VIVO
- 18F-labeling and evaluation of novel MDL 100907 derivatives as potential 5-HT2A antagonists for molecular imaging
- Preliminary in vivo and ex vivo evaluation of the 5-HT2A imaging probe [18F] MH. MZ
- A performance comparison of Sc-44 to Ga-68 using preclinical PET scanners
- Influence of different anesthesia on the brain uptake of [18F]Fallypride
- In vitro and in vivo testing of 68Ga-Schiff base derivatives for myocardial PET imaging 1582
- In vivo evaluation of pegylated [18F]harmine derivatives: Selective reversible MAO-A inhibitors
- Radiosynthesis of [18F]fluoromethyl tosylate for [18F]fluoromethylation
- 44Sc-DOTA-Puromycin: μPET-imaging of protein synthesis
- Evaluation of P-glycoprotein modulation of Fluorine-18-fallypride
- 18F-Labeling and evaluation of novel 18F-labelled MDL 100907 derivatives as potential 5-HT2A antagonists
- NMR hyperpolarization of established PET tracers for potential application as fMRI tracers
- Curcumin-based 68Ga-radiotraces: radiolabeling strategies and bifunctional chelator approach
- Impact of high energy co-emitted gamma quanta on quantification of Sc-44
- SYNTHESIS AND IN VITRO AFFINITIES OF VARIOUS MDL 100907 DERIVATIVES AS POTENTIAL 18F-RADIOLIGANDS FOR 5-HT2A RECEPTOR IMAGING WITH PET
- Dopamine, Noradrenaline and Serotonin Receptor Densities in the Striatum of Hemiparkinsonian Rats following Botulinum Neurotoxin-A Injection
- Comparison of parametric methods for the analysis of PET studies with D2-receptor ligands of different affinities: Poster No.: P13
- In vivo quantification of dopamine D2 receptor binding using PET:: Comparison of parametric images with ROI based quantification methods applied to PET ligands with different affinity.
- CHANGES IN THE EXPRESSION OF NEUROTRANSMITTER RECEPTORS IN PARKIN AND DJ-1 KNOCKOUT MICE - A QUANTITATIVE MULTIRECEPTOR STUDY
- Synthese, n.c.a. 18F-Markierung und Evaluierung von Antagonisten der Strychnin-unempfindlichen-Glycinbindungsstelle auf Basis der 4- Amino-5,7-Dichlor-1,2,3,4-Tetrahydro-Chinolin-2-Carbonsäure
- Neurotransmitter receptor density changes in pitx3(ak) mice : a model relevant to parkinson's disease
- Synthesis of 2-amino-6-(2-[18F]fluoro-pyridine-4-ylmethoxy)-9-(octyl-β-D-glucosyl)-purine:: a novel radioligand for positron emission tomography studies of the O6-methylguanine-DNA methyltransferase (MGMT) status of tumour tissue
- Two-step radiosynthesis of [18F]FE--CIT and [18F]PR04.MZ
- Total synthesis and evaluation of [18F] MHMZ
- In vitro affinities of various halogenated benzamide derivatives as potential radioligands for non-invasive quantification of D2-like dopamine receptors
- Synthesis and in vitro affinities of various MDL 100907 derivatives as potential 18F-radioligands for 5-HT2A receptor imaging with PET
- Preliminary assessment of the imaging capability of the YAP–(S) PET small animal scanner in neuroscience
- Rapid radiosynthesis of [11C] and [14C] azelaic, suberic, and sebacic acids for in vivo mechanistic studies of systemic acquired resistance in plants
- Surrogate markers for cerebral blood flow correlate with [18F]-fallypride binding potential at dopamine D2/3 receptors in human striatum
- Synthese und Nukleophile NCA 18 F-Markierung von Benzamidderivaten
- Synthesis, fluorine-18 labelling and evaluation of hydantoine-substituted indole carboxylic acids as radiotracers for imaging the NMDA-receptor status in vivo
- Serum levels of aripiprazole and dehydroaripiprazole, clinical response and side effects
- [18F]PR04. MZ for Quantification of Striatal and Extrastriatal Dopamine Transporters in Patients with Idiopathic Parkinson's Disease
- Initial human PET studies with [18F]PR04.MZ for quantification of striatal and extrastriatal dopamine transporters
- [18F]Fallypride a substrate of the abcb1ab transporter? Effects on brain imaging
- Measurement of protein synthesis: In vitro comparison of 44Sc-DOTA-Puromycin vs. [3H-Methyl]-Methionine and 35S-Methionine
- Development of a 11C-labeling method for the plant hormone azelaic acid to investigate the molecular specificity of the systemic acquired resistance (SAR) in nicotiana tabacum and zea mayz
- DETERMINATION OF POSSIBLE P-GLYCOPROTEIN INTERATION OF A NOVEL 5-HT2A LIGAND [18F] MH.MZ
- SYNTHESIS, RADIOIODINATION AND EVALUATION OF NEW MGMT-INHIBITORS AND THEIR GLUCOSE CONJUGATES
- SYNTHESIS, LABELLING AND EVALUATION OF 4,6-DICHLORO-3-((3-(4-(2-FLUOROETHOXY)PHENYL)2,4-DIOXOIMIDAZOLIDINE)-1H-INDOLE-2-CARBOXYLIC ACID AS RADIOTRACER FOR IMAGING THE NMDA-RECEPTOR STATUS IN VIVO
- Relationship between dopamine D2 receptor occupancy, clinical response, and drug and monoamine metabolites levels in plasma and cerebrospinal fluid. A pilot study in patients suffering from first-episode schizophrenia treated with quetiapine (Retracted article. See vol. 46, pg. 1108, 2012)
- Selective binding to monoamine oxidase a : in vitro and in vivo evaluation of f-18-labeled beta-carboline derivatives
- Positron emission tomography in cns drug discovery and drug monitoring
- In vitro and in vivo structure-property relationship of ga-68-labeled schiff base derivatives for functional myocardial pet imaging
- Evaluation of p-glycoprotein (abcb1a/b) modulation of [f-18]fallypride in micropet imaging studies
- Automated synthesis and purification of [18f]fluoro-[di-deutero]methyl tosylate
- 68Ga-Labelled Tropane Analogues for the Visualization of the Dopaminergic System
- Radiochemie/Tracer
- Radiosynthesis of (±)-(2-((4-(2-[18F]fluoroethoxy)phenyl)bis(4-methoxy-phenyl) methoxy)ethylpiperidine-3-carboxylic acid:: a potential GAT-3 PET ligand to study GABAergic neuro-transmission in vivo
- Pet imaging of D2-like dopamine receptors in the human brain with [18F]desmethoxyfallypride
- Efficient synthesis of 2-bromo-1-[18F]fluoroethane and its application in the automated preparation of 18F-fluoroethylated compounds
- Image quality analysis of 44Sc on two preclinical PET scanners: a comparison to 68Ga
- Gallium-68 and scandium-44 labelled radiotracers based on curcumin structure linked to bifunctional chelators: Synthesis and characterization of potential PET radiotracers
- Quantification of D2-like dopamine receptors in the human brain with 18F-desmethoxyfallypride
- On the consensus nomenclature rules for radiopharmaceutical chemistry - Reconsideration of radiochemical conversion
- High opiate receptor binding potential in the human lateral pain system
- Decreased dopamine D2/D3-receptor binding in temporal lobe epilepsy: An [18F] fallypride PET study
- Synthesis and evaluation of (S)-2-(2-[18F] fluoroethoxy)-4-([3-methyl-1-(2-piperidin-1-yl-phenyl)-butyl-carbamoyl]-methyl)-benzoic acid ([18F] repaglinide): a promising radioligand for quantification of pancreatic β-cell mass with positron emission tomography (PET)
- In vitro and in vivo evaluation of novel glibenclamide derivatives as imaging agents for the non-invasive assessment of the pancreatic islet cell mass in animals and humans
- Synthesis of 131I-Labeled Glucose-Conjugated Inhibitors of O 6-Methylguanine-DNA Methyltransferase (MGMT) and Comparison with Nonconjugated Inhibitors as Potential Tools for in Vivo MGMT Imaging
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