Autor: Efferth, Thomas / Organisationseinheit: FB 09 Chemie, Pharmazie, Geographie und Geowissenschaften

1. Artemisian-Type Compounds: From Traditional Chinese Medicine to Novel Drugs

Autoren:: Efferth, Thomas
Veröffentlichungsdatum:: 2010
Typ:: Zeitschriftenaufsatz

2. From Molecular Tumor Diagnostics to Individualized Treatment with Phytochemicals Derived from Chinese Herbs

Autoren:: Efferth, Thomas
Veröffentlichungsdatum:: 2011
Typ:: Zeitschriftenaufsatz

3. Animal plant warfare and secondary metabolite evolution

Autoren:: Wöll, Steffen; Kim, Sun Hee; Greten, Henry Johannes; Efferth, Thomas
Veröffentlichungsdatum:: 2013
Typ:: Zeitschriftenaufsatz

4. Diversity of pharmacological properties in Chinese and European medicinal plants: Cytotoxicity, antiviral and antitrypanosomal screening of 82 herbal drugs

Autoren:: Herrmann, Florian; Romero, Marta R; Blazquez, Alba G; Kaufmann, Dorothea; Ashour, Mohamed L; Kahl, Stefan; Marin, Jose JG; Efferth, Thomas; Wink, Michael
Veröffentlichungsdatum:: 2011
Typ:: Zeitschriftenaufsatz

5. Prevention of plant crown gall tumor development by the anti-malarial artesunate of Artemisia annua

Autoren:: Ullrich, Cornelia I; Eitzen-Ritter, M von; Jockel, Annemarie; Efferth, Thomas; others,
Veröffentlichungsdatum:: 2009
Typ:: Zeitschriftenaufsatz

6. Molecular determinants of response of tumor cells to berberine

Autoren:: Efferth, Thomas; Chen, Zhongping; Kaina, Bernd; Wang, Gan
Veröffentlichungsdatum:: 2005
Typ:: Zeitschriftenaufsatz

7. Biotechnology has come of age

Autoren:: Efferth, Thomas
Veröffentlichungsdatum:: 1999
Typ:: Zeitschriftenaufsatz

8. Diagnosis and objective pain assessment of traditional Chinese medicine may be useful to demonstrate specific effects of acupuncture in low back pain: A prospective, randomized, controlled and single blinded pre-study

Autoren:: Seca, Susana; Capelo, Paula; Efferth, Thomas; Doenitz, Christoph Alexander; Schroeder, Sven; Anjos, Ana; Machado, Jorge; Greten, Henry Johannes
Veröffentlichungsdatum:: 2013
Typ:: Zeitschriftenaufsatz

9. Selected secondary plant metabolites for cancer therapy

Autoren:: Fulda, Simone; Efferth, Thomas; others,
Veröffentlichungsdatum:: 2015
Typ:: Zeitschriftenaufsatz

10. Anti-inflammatory and anti-cancer activity of boswellic acids from frankincense (Boswellia serrata Roxb. et Colebr, B. carterii Birdw.)

Autoren:: Efferth, Thomas; Greten, Henry Johannes
Veröffentlichungsdatum:: 2011
Typ:: Zeitschriftenaufsatz

11. Treatment of Iron-Loaded Veterinary Sarcoma by Artemisia annua

Autoren:: Breuer, Elmar; Efferth, Thomas
Veröffentlichungsdatum:: 2014
Typ:: Zeitschriftenaufsatz

12. Adaptogens in chemobrain (Part III): Antitoxic effects of plant extracts towards cancer chemotherapy-induced toxicity - transcriptome-wide microarray analysis of neuroglia cells

Autoren:: Seo, Ean-Jeong; Klauck, Sabine M; Efferth, Thomas; Panossian, Alexander
Veröffentlichungsdatum:: 2019
Typ:: Zeitschriftenaufsatz

13. Molecular bases of the poor response of liver cancer to chemotherapy

Autoren:: Marin, Jose JG; Briz, Oscar; Herraez, Elisa; Lozano, Elisa; Asensio, Maitane; Di Giacomo, Silvia; Romero, Marta R; Osorio-Padilla, Luis M; Santos-Llamas, Ana I; Serrano, Maria A; Armengol, Carolina; Efferth, Thomas; Macias, Rocio IR
Veröffentlichungsdatum:: 2018
Typ:: Zeitschriftenaufsatz

14. Cryptotanshinone deregulates unfolded protein response and eukaryotic initiation factor signaling in acute lymphoblastic leukemia cells

Autoren:: Wu, Ching-Fen; Seo, Ean-Jeong; Klauck, Sabine M; Efferth, Thomas
Veröffentlichungsdatum:: 2016
Typ:: Zeitschriftenaufsatz

15. Antiangiogenic Activity and Pharmacogenomics of Medicinal Plants from Traditional Korean Medicine

Autoren:: Seo, Ean-Jeong; Kuete, Victor; Kadioglu, Onat; Krusche, Benjamin; Schroeder, Sven; Greten, Henry Johannes; Arend, Joachim; Lee, Ik-Soo; Efferth, Thomas
Veröffentlichungsdatum:: 2013
Typ:: Zeitschriftenaufsatz

16. First Study of Oral Artenimol-R in Advanced Cervical Cancer: Clinical Benefit, Tolerability and Tumor Markers

Autoren:: Jansen, Frans Herwig; Adoubi, Innocent; Comoe, Kouassi JC; De Cnodder, Tinne; Jansen, Nicolas; Tschulakow, Alexander; Efferth, Thomas
Veröffentlichungsdatum:: 2011
Typ:: Zeitschriftenaufsatz

17. Phytomedicine in Otorhinolaryngology and Pulmonology: Clinical Trials with Herbal Remedies

Autoren:: Ghazi-Moghadam, Koosha; Inançlı, Hasan Mete; Bazazy, Nazanin; Plinkert, Peter K; Efferth, Thomas; Sertel, Serkan
Veröffentlichungsdatum:: 2012
Typ:: Zeitschriftenaufsatz

18. Natural Products in Structure-Assisted Design of Molecular Cancer Therapeutics

Autoren:: Pfisterer, Petra H; Wolber, Gerhard; Efferth, Thomas; Rollinger, Judith M; Stuppner, Hermann
Veröffentlichungsdatum:: 2010
Typ:: Zeitschriftenaufsatz

19. Effect of artesunate on immune cells in ret-transgenic mouse melanoma model

Autoren:: Ramacher, Marcel; Umansky, Viktor; Efferth, Thomas
Veröffentlichungsdatum:: 2009
Typ:: Zeitschriftenaufsatz

20. Epidermal Growth Factor Receptors and Downstream Signalling Pathways as Cancer Treatment Targets for Medicinal Plants

Autoren:: Seo, Ean-Jeong; Wu, Ching-Fen; Greten, Henny J; Efferth, Thomas
Veröffentlichungsdatum:: 2015
Typ:: Kapitel

21. MODULATION OF CORTICOTROPIN RELEASING HORMONE SIGNALING IN MOUSE INTESTINAL ORGANOIDS BY STW 5-II: POSSIBLE MECHANISMS FOR THE MANGAEMNT OF DISORDERS OF GUT-BRAIN INTERACTIONS

Autoren:: Elbadawi, Mohamed A; Ammar, Ramy M; Rabini, Sabine; Efferth, Thomas
Veröffentlichungsdatum:: 2022
Typ:: Konferenzbeitrag

22. Animals and animal toxins in traditional and modern medicine

Autoren:: Kaufmann, Anke; Greten, Henry Johannes; Efferth, Thomas
Veröffentlichungsdatum:: 2014
Typ:: Zeitschriftenaufsatz

23. Cell growth of sunitinib-resistant renal cell carcinoma was inhibited by Shikonin through necroptosis induction and Akt/mTOR signaling inhibition.

Autoren:: Juengel, Eva; Markowitsch, Sascha D; Vakhrusheva, Olesya; Akele, Yasminn; Kitanovic, Jovanna; Schupp, Patricia; Slade, Kimberly S; Thomas, Anita; Tsaur, Igor; Mager, Rene; Efferth, Thomas; Haferkamp, Axel
Veröffentlichungsdatum:: 2022
Typ:: Konferenzbeitrag

24. Cell growth of sunitinib-resistant renal cell carcinoma was inhibited by Shikonin through necroptosis induction and Akt/mTOR signaling inhibition

Autoren:: Juengel, Eva; Markowitsch, Sascha D; Vakhrusheva, Olesya; Akele, Yasminn; Kitanovic, Jovanna; Schupp, Patricia; Slade, Kimberly S; Thomas, Anita; Tsaur, Igor; Mager, Rene; Efferth, Thomas; Haferkamp, Axel
Veröffentlichungsdatum:: 2022
Typ:: Konferenzbeitrag

25. Editorial: Phytonutrients in the treatment of cancer: Mechanistic insights and therapeutic prospects

Autoren:: Khan, Haroon; Efferth, Thomas; Tejada, Silvia
Veröffentlichungsdatum:: 2023
Typ:: Zeitschriftenaufsatz

26. Jozibrevine D from Ancistrocladus ileboensis, the fifth alkaloid in a series of six possible atropo-diastereomeric naphthylisoquinoline dimers, showing antiparasitic and antileukemic activities

Autoren:: Li, Jun; Tajuddeen, Nasir; Feineis, Doris; Mudogo, Virima; Kaiser, Marcel; Seo, Ean-Jeong; Efferth, Thomas; Bringmann, Gerhard
Veröffentlichungsdatum:: 2023
Typ:: Zeitschriftenaufsatz

27. Phytochemical profiling of polyphenols and thyroid stimulatory activity of Ficus religiosa leaf extract in 6-propyl-thiouracil-induced hypothyroid rats

Autoren:: Kar, Anand; Mahar, Durgesh; Biswas, Sagarika; Chakraborty, Debolina; Efferth, Thomas; Panda, Sunanda
Veröffentlichungsdatum:: 2023
Typ:: Zeitschriftenaufsatz

28. In Silico and In Vitro Identification of P-Glycoprotein Inhibitors from a Library of 375 Phytochemicals

Autoren:: Schaefer, Julia; Kloesgen, Vincent Julius; Omer, Ejlal A; Kadioglu, Onat; Mbaveng, Armelle T; Kuete, Victor; Hildebrandt, Andreas; Efferth, Thomas
Veröffentlichungsdatum:: 2023
Typ:: Zeitschriftenaufsatz

29. The Effect of Plastic-Related Compounds on Transcriptome-Wide Gene Expression on CYP2C19-Overexpressing HepG2 Cells

Autoren:: Rosellini, Matteo; Schulze, Alicia; Omer, Ejlal A; Ali, Nadeen T; Marini, Federico; Kuepper, Jan-Heiner; Efferth, Thomas
Veröffentlichungsdatum:: 2023
Typ:: Zeitschriftenaufsatz

30. A critical review of machine-learning for "multi-omics" marine metabolite datasets

Autoren:: Manochkumar, Janani; Cherukuri, Aswani Kumar; Kumar, Raju Suresh; Almansour, Abdulrahman I; Ramamoorthy, Siva; Efferth, Thomas
Veröffentlichungsdatum:: 2023
Typ:: Zeitschriftenaufsatz

31. Cytotoxicity, acute and sub-chronic toxicities of the leaves of Bauhinia thonningii (Schumach.) Milne-Redh. (Caesalpiniaceae)

Autoren:: Matieta, Valaire Y; Mbaveng, Armelle T; Nouemsi, Guy R Sado; Tankeo, Simplice B; Kamsu, Gabriel T; Nayim, Paul; Lannang, Alain M; Celik, Ilhami; Efferth, Thomas; Kuete, Victor
Veröffentlichungsdatum:: 2023
Typ:: Zeitschriftenaufsatz

32. Anticancer activity of Bacopa monnieri through apoptosis induction and mitophagy-dependent NLRP3 inflammasome inhibition in oral squamous cell carcinoma

Autoren:: Mishra, Soumya Ranjan; Behera, Bishnu Prasad; Singh, Vineet Kumar; Mahapatra, Kewal Kumar; Mundkinajeddu, Deepak; Bhat, Deeksha; Minz, Aruna Mukti; Sethi, Gautam; Efferth, Thomas; Das, Surajit; Bhutia, Sujit Kumar
Veröffentlichungsdatum:: 2024
Typ:: Zeitschriftenaufsatz

33. Drug repurposing using transcriptome sequencing and virtual drug screening in a patient with glioblastoma

Autoren:: Saeed, Mohamed EM; Kadioglu, Onat; Greten, Henry Johannes; Yildirim, Adem; Mayr, Katharina; Wenz, Frederik; Giordano, Frank A; Efferth, Thomas
Veröffentlichungsdatum:: 2021
Typ:: Zeitschriftenaufsatz

34. Antiproliferative Properties of a Few Auranofin-Related Gold (I) and Silver (I) Complexes in Leukemia Cells and their Interferences with the Ubiquitin Proteasome System

Autoren:: Cirri, Damiano; Schirmeister, Tanja; Seo, Ean-Jeong; Efferth, Thomas; Massai, Lara; Messori, Luigi; Micale, Nicola
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

35. Identification of NF-κB as Determinant of Posttraumatic Stress Disorder and Its Inhibition by the Chinese Herbal Remedy Free and Easy Wanderer

Autoren:: Hong, Chunlan; Schueffler, Anja; Kauhl, Ulrich; Cao, Jingming; Wu, Ching-Fen; Opatz, Till; Thines, Eckhard; Efferth, Thomas
Veröffentlichungsdatum:: 2017
Typ:: Zeitschriftenaufsatz

36. Elatumic Acid: A New Ursolic Acid Congener from Omphalocarpum elatum Miers (Sapotaceae)

Autoren:: Sandjo, Louis P; Fru, Chi G; Kuete, Victor; Nana, Frederic; Yeboah, Samuel O; Mapitse, Renameditswe; Abegaz, Berhanu M; Efferth, Thomas; Opatz, Till; Ngadjui, Bonaventure T
Veröffentlichungsdatum:: 2014
Typ:: Zeitschriftenaufsatz

37. West meets east: open up a dialogue on phytomedicine

Autoren:: Li, Xiuzhu; Chen, Weijie; Simal-Gandara, Jesus; Georgiev, Milen I; Li, Hongyi; Hu, Hao; Wu, Xu; Efferth, Thomas; Wang, Shengpeng
Veröffentlichungsdatum:: 2021
Typ:: Zeitschriftenaufsatz

38. The triterpenoid ursolic acid ameliorates stress in Caenorhabditis elegans by affecting the depression-associated genes skn-1 and prdx2

Autoren:: Nass, Janine; Abdelfatah, Sara; Efferth, Thomas
Veröffentlichungsdatum:: 2021
Typ:: Zeitschriftenaufsatz

39. Anti-inflammatory and tight junction protective activity of the herbal preparation STW 5-II on mouse intestinal organoids

Autoren:: Elbadawi, Mohamed; Ammar, Ramy M; Aziz-Kalbhenn, Heba; Rabini, Sabine; Klauck, Sabine M; Dawood, Mona; Saeed, Mohamed EM; Kampf, Christopher J; Efferth, Thomas
Veröffentlichungsdatum:: 2021
Typ:: Zeitschriftenaufsatz

40. Role of Levo-tetrahydropalmatine and its metabolites for management of chronic pain and opioid use disorders

Autoren:: Liu, Jing; Dai, Ronghua; Damiescu, Roxana; Efferth, Thomas; Lee, David YW
Veröffentlichungsdatum:: 2021
Typ:: Zeitschriftenaufsatz

41. In Vitro and In Silico Studies of Two 1,4-Naphthoquinones and their Topi- cal Formulation in Bigels

Autoren:: Khelifi, Imen; Tourrette, Audrey; Khelifi, Daycem; Efferth, Thomas; Hayouni, El Akrem; Ksouri, Riadh; Bouajila, Jalloul
Veröffentlichungsdatum:: 2021
Typ:: Zeitschriftenaufsatz

42. Botanicals and phytochemicals from the bark of Hypericum roeperianum (Hypericaceae) had strong antibacterial activity and showed synergistic effects with antibiotics against multidrug-resistant bacteria expressing active efflux pumps

Autoren:: Demgne, Olive Monique F; Damen, Francois; Fankam, Aime G; Guefack, Michel-Gael F; Wamba, Brice EN; Nayim, Paul; Mbaveng, Armelle T; Bitchagno, Gabin TM; Tapondjou, Leon Azefack; Penlap, Veronique B; Tane, Pierre; Efferth, Thomas; Kuete, Victor
Veröffentlichungsdatum:: 2021
Typ:: Zeitschriftenaufsatz

43. Cytotoxic alkaloids from the root of Zanthoxylum paracanthum (mildbr) Kokwaro

Autoren:: Omosa, Leonidah Kerubo; Nchiozem-Ngnitedem, Vaderament-A; Mukavi, Justus; Atieno Okoko, Brenda; Ombui Nyaboke, Helder; Hashim, Ibrahim; Obegi Matundura, Jackson; Efferth, Thomas; Spiteller, Michael
Veröffentlichungsdatum:: 2022
Typ:: Zeitschriftenaufsatz

44. Identification of novel drug resistance mechanisms by genomic and transcriptomic profiling of glioblastoma cells with mutation-activated EGFR

Autoren:: Kadioglu, Onat; Saeed, Mohamed EM; Mahmoud, Nuha; Azawi, Shaymaa; Mrasek, Kristin; Liehr, Thomas; Efferth, Thomas
Veröffentlichungsdatum:: 2021
Typ:: Zeitschriftenaufsatz

45. Withanone Ameliorates Stress Symptoms in Caenorhabditis Elegans by Acting through Serotonin Receptors

Autoren:: Nass, Janine; Efferth, Thomas
Veröffentlichungsdatum:: 2021
Typ:: Zeitschriftenaufsatz

46. Increased Stress Resistance and Lifespan in Chaenorhabditis elegans Wildtype and Knockout Mutants-Implications for Depression Treatment by Medicinal Herbs

Autoren:: Nass, Janine; Kampf, Christopher J; Efferth, Thomas
Veröffentlichungsdatum:: 2021
Typ:: Zeitschriftenaufsatz

47. Bioactivity of fractions and constituents of Piper capense fruits towards a broad panel of cancer cells

Autoren:: Mbaveng, Armelle T; Wamba, Brice EN; Bitchagno, Gabin TM; Tankeo, Simplice Beaudelaire; Celik, Ilhami; Atontsa, Brice CK; Lonfouo, Antoine H Nkuete; Kuete, Victor; Efferth, Thomas
Veröffentlichungsdatum:: 2021
Typ:: Zeitschriftenaufsatz

48. Toxicity as prime selection criterion among SARS-active herbal medications

Autoren:: Oesch, Franz; Oesch-Bartlomowicz, Barbara; Efferth, Thomas
Veröffentlichungsdatum:: 2021
Typ:: Zeitschriftenaufsatz

49. Artesunate Impairs Growth in Cisplatin-Resistant Bladder Cancer Cells by Cell Cycle Arrest, Apoptosis and Autophagy Induction

Autoren:: Zhao, Fuguang; Vakhrusheva, Olesya; Markowitsch, Sascha D; Slade, Kimberly S; Tsaur, Igor; Cinatl, Jindrich Jr; Michaelis, Martin; Efferth, Thomas; Haferkamp, Axel; Juengel, Eva
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

50. Ursolic acid ameliorates stress and reactive oxygen species in C. elegans knockout mutants by the dopamine Dop1 and Dop3 receptors

Autoren:: Nass, Janine; Efferth, Thomas
Veröffentlichungsdatum:: 2021
Typ:: Zeitschriftenaufsatz

51. Identification of metastasis-related genes by genomic and transcriptomic studies in murine melanoma

Autoren:: Kadioglu, Onat; Saeed, Mohamed EM; Mahmoud, Nuha; Azawi, Shaymaa S Hussein; Rincic, Martina; Liehr, Thomas; Efferth, Thomas
Veröffentlichungsdatum:: 2021
Typ:: Zeitschriftenaufsatz

52. AMG900 as novel inhibitor of the translationally controlled tumor protein

Autoren:: Fischer, Nicolas; Seo, Ean-Jeong; Klinger, Anette; Fleischer, Edmond; Efferth, Thomas
Veröffentlichungsdatum:: 2021
Typ:: Zeitschriftenaufsatz

53. Genomic landscape analyses in cervical carcinoma and consequences for treatment

Autoren:: Diefenbach, Dominik; Greten, Henry Johannes; Efferth, Thomas
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

54. Exploring natural products-based cancer therapeutics derived from egyptian flora

Autoren:: El-Seedi, Hesham R; Yosri, Nermeen; Khalifa, Shaden AM; Guo, Zhiming; Musharraf, Syed Ghulam; Xiao, Jianbo; Saeed, Aamer; Du, Ming; Khatib, Alfi; Abdel-Daim, Mohamed M; Efferth, Thomas; Goransson, Ulf; Verpoorte, Rob
Veröffentlichungsdatum:: 2021
Typ:: Zeitschriftenaufsatz

55. Induction of Apoptosis, Autophagy and Ferroptosis by Thymus vulgaris and Arctium lappa Extract in Leukemia and Multiple Myeloma Cell Lines

Autoren:: N. Adham, Aveen; F. Hegazy, Mohamed Elamir; Naqishbandi, Alaadin M; Efferth, Thomas
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

56. Cytotoxicity and apoptosis induction by Fumaria officinalis extracts in leukemia and multiple myeloma cell lines

Autoren:: Adham, Aveen N; Naqishbandi, Alaadin M; Efferth, Thomas
Veröffentlichungsdatum:: 2021
Typ:: Zeitschriftenaufsatz

57. Multiple modes of cell death in neuroendocrine tumors induced by artesunate

Autoren:: Yan, Ge; Dawood, Mona; Boeckers, Madeleine; Klauck, Sabine M; Fottner, Christian; Weber, Matthias M; Efferth, Thomas
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

58. Evaluation of Long-Time Decoction-DetoxicatedHei-Shun-Pian(ProcessedAconitum carmichaeliDebeaux Lateral Root With Peel) for Its Acute Toxicity and Therapeutic Effect on Mono-Iodoacetate Induced Osteoarthritis

Autoren:: Zhang, Lei; Li, Ting; Wang, Rongrong; Xu, Jiaan; Zhou, Li; Yan, Li; Hu, Zhengyan; Li, Hongwen; Liu, Fucun; Du, Wenxi; Tong, Peijian; Wu, Huiling; Zhang, Shanxing; Shan, Letian; Efferth, Thomas
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

59. Salvia ceratophyllaL. from South of Jordan: new insights on chemical composition and biological activities

Autoren:: Abu-Darwish, Mohammad Sanad; Cabral, Celia; Ali, Zulfigar; Wang, Mei; Khan, Shabana I; Jacob, Melissa R; Jain, Surendra K; Tekwani, Babu L; Zulfiqar, Fazila; Khan, Ikhlas A; Taifour, Hatem; Salgueiro, Ligia; Efferth, Thomas
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

60. Steroidal saponins from Raphia vinifera and their cytotoxic activity

Autoren:: Chi, Godloves Fru; Sop, Rodrigue VT; Mbaveng, Armelle T; Ombito, Japheth Omollo; Fotso, Ghislain Wabo; Nguenang, Gaelle S; Kuete, Victor; Efferth, Thomas; Ngadjui, Bonaventure T
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

61. Comprehensive Overview on Multiple Strategies Fighting COVID-19

Autoren:: Khalifa, Shaden AM; Mohamed, Briksam S; Elashal, Mohamed H; Du, Ming; Guo, Zhiming; Zhao, Chao; Musharraf, Syed Ghulam; Boskabady, Mohammad H; El-Seedi, Haged HR; Efferth, Thomas; El-Seedi, Hesham R
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

62. Cytotoxic bufadienolides from the leaves of a medicinal plant Melianthus comosus collected in South Africa

Autoren:: Bedane, Kibrom Gebreheiwot; Brieger, Lukas; Strohmann, Carsten; Seo, Ean-Jeong; Efferth, Thomas; Spiteller, Michael
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

63. Identification of potential inhibitors targeting BRAF-V600E mutant melanoma cells

Autoren:: Kadioglu, Onat; Saeed, Mohamed EM; Greten, Henry J; Mayr, Katharina; Schrama, David; Roos, Wynand P; Efferth, Thomas
Veröffentlichungsdatum:: 2021
Typ:: Zeitschriftenaufsatz

64. Investigation of cancer drug resistance mechanisms by phosphoproteomics

Autoren:: Boulos, Joelle C; Idres, Muhammad Rahama Yousof; Efferth, Thomas
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

65. Putative molecular determinants mediating sensitivity or resistance towards carnosic acid tumor cell responses

Autoren:: Mahmoud, Nuha; Saeed, Mohamed EM; Sugimoto, Yoshikazu; Klinger, Anette; Fleischer, Edmond; Efferth, Thomas
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

66. Cytotoxic Bufadienolides from the Leaves of Melianthus major

Autoren:: Bedane, Kibrom Gebreheiwot; Brieger, Lukas; Strohmann, Carsten; Seo, Ean-Jeong; Efferth, Thomas; Spiteller, Michael
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

67. Targeting epigenetics in cancer: therapeutic potential of flavonoids

Autoren:: Khan, Haroon; Belwal, Tarun; Efferth, Thomas; Farooqi, Ammad Ahmad; Sanches-Silva, Ana; Vacca, Rosa Anna; Nabavi, Seyed Fazel; Khan, Fazlullah; Prasad Devkota, Hari; Barreca, Davide; Sureda, Antoni; Tejada, Silvia; Dacrema, Marco; Daglia, Maria; Suntar, Ipek; Xu, Suowen; Ullah, Hammad; Battino, Maurizio; Giampieri, Francesca; Nabavi, Seyed Mohammad
Veröffentlichungsdatum:: 2021
Typ:: Zeitschriftenaufsatz

68. Immunotoxicity of Therapeutic Antibodies and Nanoparticles

Autoren:: Ozenver, Nadire; Efferth, Thomas
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

69. Organoids of human airways to study infectivity and cytopathy of SARS-CoV-2

Autoren:: Elbadawi, Mohamed; Efferth, Thomas
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

70. 8,8-bis-(Dihydroconiferyl)-diferulate displayed impressive cytotoxicity towards a panel of human and animal cancer cells

Autoren:: Mbaveng, Armelle T; Damen, Francois; Guefack, Michel-Gael F; Tankeo, Simplice Beaudelaire; Abdelfatah, Sara; Bitchagno, Gabin TM; Celik, Ilhami; Kuete, Victor; Efferth, Thomas
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

71. Cryptochlorogenic acid attenuates LPS-induced inflammatory response and oxidative stress via upregulation of the Nrf2/HO-1 signaling pathway in RAW 264.7 macrophages

Autoren:: Zhao, Xue-Lian; Yu, Liang; Zhang, Sun-Dong; Ping, Kou; Ni, Hai-Yan; Qin, Xiang-Yu; Zhao, Chun-Jian; Wang, Wei; Efferth, Thomas; Fu, Yu-Jie
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

72. Indeno[1,2,3-cd]pyrene and picene mediate actions via estrogen receptor α signaling pathway in in vitro cell systems, altering gene expression

Autoren:: Boeckers, Madeleine; Paul, Norbert W; Efferth, Thomas
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

73. Small molecule inhibitors and stimulators of inducible nitric oxide synthase in cancer cells from natural origin (phytochemicals, marine compounds, antibiotics)

Autoren:: Oezenver, Nadire; Efferth, Thomas
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

74. Retrospective study of small pet tumors treated with Artemisia annua and iron

Autoren:: Saeed, Mohamed EM; Breuer, Elmar; Hegazy, Mohamed-Elamir F; Efferth, Thomas
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

75. The antioxidant 2,3-dichloro,5,8-dihydroxy,1,4-naphthoquinone inhibits acetyl-cholinesterase activity and amyloid β42 aggregation: A dual target therapeutic candidate compound for the treatment of Alzheimer's disease

Autoren:: Khelifi, Imen; Tourrette, Audrey; Dhouafli, Zohra; Bouajila, Jalloul; Efferth, Thomas; Abdelfatah, Sara; Ksouri, Riadh; Hayouni, El Akrem
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

76. Terpenoid bio-transformations and applications via cell/organ cultures: a systematic review

Autoren:: Hegazy, Mohamed-Elamir F; Elshamy, Abdelsamed I; Mohamed, Tarik A; Hussien, Taha A; Helaly, Soleiman E; Abdel-Azim, Nahla S; Shams, Khaled A; Shahat, Abdelaaty A; Tawfik, Wafaa A; Shahen, Alaa M; Debbab, Abdessamad; El Saedi, Hesham R; Mohamed, Abou El-Hamd H; Hammouda, Faiza M; Sakr, Mahmoud; Pare, Paul W; Efferth, Thomas
Veröffentlichungsdatum:: 2020
Typ:: Zeitschriftenaufsatz

77. A Machine Learning-Based Prediction Platform for P-Glycoprotein Modulators and Its Validation by Molecular Docking

Autoren:: Kadioglu, Onat; Efferth, Thomas
Veröffentlichungsdatum:: 2019
Typ:: Zeitschriftenaufsatz

78. Comparison between tumors in plants and human beings: Mechanisms of tumor development and therapy with secondary plant metabolites

Autoren:: Ullrich, Cornelia I; Aloni, Roni; Saeed, Mohamed EM; Ullrich, Wolfram; Efferth, Thomas
Veröffentlichungsdatum:: 2019
Typ:: Zeitschriftenaufsatz

79. Combining the wisdoms of traditional medicine with cutting-edge science and technology at the forefront of medical sciences

Autoren:: Efferth, Thomas; Xu, An-Long; Lee, David YW
Veröffentlichungsdatum:: 2019
Typ:: Zeitschriftenaufsatz

80. Interactions between artemisinin derivatives and P-glycoprotein

Autoren:: Wang, Yulin; Li, Yongjie; Shang, Dong; Efferth, Thomas
Veröffentlichungsdatum:: 2019
Typ:: Zeitschriftenaufsatz

81. Professor Hildebert Wagner celebrates his 90th birthday

Autoren:: Efferth, Thomas
Veröffentlichungsdatum:: 2019
Typ:: Zeitschriftenaufsatz

82. Broad-spectrum Cross-resistance to Anticancer Drugs Mediated by Epidermal Growth Factor Receptor

Autoren:: Yan, Ge; Efferth, Thomas
Veröffentlichungsdatum:: 2019
Typ:: Zeitschriftenaufsatz

83. Antiulcer activity of Cyperus alternifolius in relation to its UPLC-MS metabolite fingerprint: A mechanistic study

Autoren:: Farrag, Abdel Razik H; Abdallah, Heba MI; Khattab, Amira R; Elshamy, Abdelsamed I; El Gendy, Abd El-Nasser G; Mohamed, Tarik A; Farag, Mohamed A; Efferth, Thomas; Hegazy, Mohamed-Elamir F
Veröffentlichungsdatum:: 2019
Typ:: Zeitschriftenaufsatz

84. Editorial: Chemoprevention of cancer by natural products

Autoren:: Efferth, Thomas
Veröffentlichungsdatum:: 2019
Typ:: Zeitschriftenaufsatz

85. Plants mentioned in the Islamic Scriptures (Holy Qur'an and Ahadith): Traditional uses and medicinal importance in contemporary times

Autoren:: El-Seedi, Hesham R; Khalifa, Shaden AM; Yosri, Nermeen; Khatib, Alfi; Chen, Lei; Saeed, Aamer; Efferth, Thomas; Verpoorte, Rob
Veröffentlichungsdatum:: 2019
Typ:: Zeitschriftenaufsatz

86. Ca2+ signalling plays a role in celastrol-mediated suppression of synovial fibroblasts of rheumatoid arthritis patients and experimental arthritis in rats

Autoren:: Wong, Vincent Kam Wai; Qiu, Congling; Xu, Su-Wei; Law, Betty Yuen Kwan; Zeng, Wu; Wang, Hui; Michelangeli, Francesco; Dias, Ivo Ricardo De Seabra Rodrigues; Qu, Yuan Qing; Chan, Tsz Wai; Han, Yu; Zhang, Ni; Mok, Simon Wing Fai; Chen, Xi; Yu, Lu; Pan, Hudan; Hamdoun, Sami; Efferth, Thomas; Yu, Wen Jing; Zhang, Wei; Li, Zheng; Xie, Yuesheng; Luo, Riqiang; Jiang, Quan; Liu, Liang
Veröffentlichungsdatum:: 2019
Typ:: Zeitschriftenaufsatz

87. Chondroprotective effects of platelet lysate towards monoiodoacetate-induced arthritis by suppression of TNF-α-induced activation of NF-κB pathway in chondrocytes

Autoren:: Yan, Li; Zhou, Li; Xie, Danting; Du, Wenxi; Chen, Fangming; Yuan, Qiang; Tong, Peijian; Shan, Letian; Efferth, Thomas
Veröffentlichungsdatum:: 2019
Typ:: Zeitschriftenaufsatz

88. Collateral sensitivity of drug-resistant ABCB5-and mutation-activated EGFR overexpressing cells towards resveratrol due to modulation of SIRT1 expression

Autoren:: Saeed, Mohamed EM; Rahama, Muhammad; Kuete, Victor; Dawooda, Mona; Elbadawi, Mohamed; Sugimoto, Yoshikazu; Efferth, Thomas
Veröffentlichungsdatum:: 2019
Typ:: Zeitschriftenaufsatz

89. Relationship between EGFR expression and subcellular localization with cancer development and clinical outcome

Autoren:: Yan, Ge; Saeed, Mohamed EM; Foersch, Sebastian; Schneider, Jose; Roth, Wilfried; Efferth, Thomas
Veröffentlichungsdatum:: 2019
Typ:: Zeitschriftenaufsatz

90. Adaptogens in chemobrain (Part II): Effect of plant extracts on chemotherapy-induced cytotoxicity in neuroglia cells

Autoren:: Seo, Ean-Jeong; Klauck, Sabine M; Efferth, Thomas; Panossian, Alexander
Veröffentlichungsdatum:: 2019
Typ:: Zeitschriftenaufsatz

91. 2′-O-galloylhyperin attenuates LPS-induced acute lung injury via upregulation antioxidation and inhibition of inflammatory responses in vivo

Autoren:: Zhang, Sun-Dong; Wang, Peng; Zhang, Jing; Wang, Wei; Yao, Li-Ping; Gu, Cheng-Bo; Efferth, Thomas; Fu, Yu-Jie
Veröffentlichungsdatum:: 2019
Typ:: Zeitschriftenaufsatz

92. Adaptogens in chemobrain (Part I): Plant extracts attenuate cancer chemotherapy-induced cognitive impairment - Transcriptome-wide microarray profiles of neuroglia cells

Autoren:: Seo, Ean-Jeong; Klauck, Sabine M; Efferth, Thomas; Panossian, Alexander
Veröffentlichungsdatum:: 2019
Typ:: Zeitschriftenaufsatz

93. IN VIVO ACUTE TOXICITY OF DETOXIFIED FUZI (LATERAL ROOT OF ACONITUM CARMICHAELI) AFTER A TRADITIONAL DETOXIFICATION PROCESS

Autoren:: Sun, Wan; Yan, Bo; Wang, Rongrong; Liu, Fucun; Hu, Zhengyan; Zhou, Li; Yan, Li; Zhou, Kang; Huang, Jiawei; Tong, Peijian; Shan, Letian; Efferth, Thomas
Veröffentlichungsdatum:: 2018
Typ:: Zeitschriftenaufsatz

94. Cardenolides: Insights from chemical structure and pharmacological utility

Autoren:: El-Seedi, Hesham R; Khalifa, Shaden AM; Taher, Eman A; Farag, Mohamed A; Saeed, Aamer; Gamal, Mohamed; Hegazy, Mohamed-Elamir F; Youssef, Diaa; Musharraf, Syed G; Alajlani, Muaaz M; Xiao, Jianbo; Efferth, Thomas
Veröffentlichungsdatum:: 2019
Typ:: Zeitschriftenaufsatz

95. Cell Harvesting Methods Affect Cellular Integrity of Adherent Cells During Apoptosis Detection

Autoren:: Yan, Ge; Efferth, Thomas
Veröffentlichungsdatum:: 2018
Typ:: Zeitschriftenaufsatz

96. Agkistrodon ameliorates pain response and prevents cartilage degradation in monosodium iodoacetate-induced osteoarthritic rats by inhibiting chondrocyte hypertrophy and apoptosis

Autoren:: Wang, Caiwei; Yan, Li; Yan, Bo; Zhou, Li; Sun, Wan; Yu, Lingying; Liu, Fucun; Du, Wenxi; Yu, Guangping; Hu, Zhengyan; Yuan, Qiang; Xiao, Luwei; Li, Hongwen; Tong, Peijian; Zhang, Jida; Shan, Letian; Efferth, Thomas
Veröffentlichungsdatum:: 2019
Typ:: Zeitschriftenaufsatz

97. Intra-Articular Injection of Fructus Ligustri Lucidi Extract Attenuates Pain Behavior and Cartilage Degeneration in Mono-Iodoacetate Induced Osteoarthritic Rats

Autoren:: Yan, Bo; Zhou, Li; Wang, Caiwei; Wang, Rongrong; Yan, Li; Yu, Lingying; Liu, Fucun; Du, Wenxi; Yu, Guangping; Yuan, Qiang; Tong, Peijian; Shan, Letian; Efferth, Thomas
Veröffentlichungsdatum:: 2018
Typ:: Zeitschriftenaufsatz

98. Cytotoxicity of nimbolide towards multidrug-resistant tumor cells and hypersensitivity via cellular metabolic modulation

Autoren:: Mahmoud, Nuha; Saeed, Mohamed EM; Sugimoto, Yoshikazu; Klauck, Sabine M; Greten, Henry J; Efferth, Thomas
Veröffentlichungsdatum:: 2018
Typ:: Zeitschriftenaufsatz

99. Curcumin downregulates expression of opioid-related nociceptin receptor gene (OPRL1) in isolated neuroglia cells

Autoren:: Seo, Ean-Jeong; Efferth, Thomas; Panossian, Alexander
Veröffentlichungsdatum:: 2018
Typ:: Zeitschriftenaufsatz

100. Epimagnolin A, a tetrahydrofurofuranoid lignan from Magnolia fargesii, reverses ABCB1-mediated drug resistance

Autoren:: Mitani, Yuji; Satake, Kazuhiro; Tsukamoto, Megumi; Nakamura, Ichiro; Kadioglu, Onat; Teruya, Toshiaki; Yonezawa, Takayuki; Byung-Yoon, Cha; Efferth, Thomas; Je-Tae, Woo; Nakagawa, Hiroshi
Veröffentlichungsdatum:: 2018
Typ:: Zeitschriftenaufsatz

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