Simulation of plasticity in the adult visual cortex

Publication type:
Journal article
Metadata:
Autoren
  • MA Andrade
  • EM Muro
  • F Morán
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000169042400005&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.1007/PL00007988
eISSN
1432-0770
Externe Identifier
  • Clarivate Analytics Document Solution ID: 438FF
  • PubMed Identifier: 11417056
ISSN
0340-1200
Ausgabe der Veröffentlichung
6
Zeitschrift
BIOLOGICAL CYBERNETICS
Paginierung
445 - 451
Datum der Veröffentlichung
2001
Status
Published
Titel
Simulation of plasticity in the adult visual cortex
Sub types
  • Article
Ausgabe der Zeitschrift
84

Data source: Web of Science (Lite)

Other metadata sources:
Autoren
  • Miguel A Andrade
  • Enrique M Muro
  • Federico Morán
DOI
10.1007/pl00007988
ISSN
0340-1200
Ausgabe der Veröffentlichung
6
Zeitschrift
Biological Cybernetics
Sprache
en
Paginierung
445 - 451
Datum der Veröffentlichung
2001
Status
Published
Herausgeber
Springer Science and Business Media LLC
Herausgeber URL
http://dx.doi.org/10.1007/pl00007988
Datum der Datenerfassung
2019
Titel
Simulation of plasticity in the adult visual cortex
Ausgabe der Zeitschrift
84

Data source: Crossref

Abstract
Retinal plasticity has been shown in the adult visual nervous system in mammals. Following a retinal lesion (scotoma) there is a reorganization of the cortical receptive field distribution: cortical neurons selective to visual stimuli in the area of the visual field corresponding to the retinal lesion, become selective to other parts of the visual field. In this work, we study this effect with a self-organizing neural network. In a first stage, the network reaches a pattern of connectivity that represents normal development of neuronal selectivity. The scotoma is simulated by perturbing accordingly the properties of a region of the input layer representing the retina. The system evolves to a new receptive field distribution mainly by means of the reorganization of the intra cortical connectivity. No major change of the geniculo cortical connectivity is detected. This may explain the surprisingly short time scale of the event.
Addresses
  • Departamento de Bioquímica y Biología Molecular I, Facultad de Químicas, Universidad Complutense de Madrid, 28040 Madrid, Spain.
Autoren
  • MA Andrade
  • EM Muro
  • F Morán
DOI
10.1007/pl00007988
eISSN
1432-0770
Externe Identifier
  • PubMed Identifier: 11417056
Open access
false
ISSN
0340-1200
Ausgabe der Veröffentlichung
6
Zeitschrift
Biological cybernetics
Schlüsselwörter
  • Visual Cortex
  • Animals
  • Mammals
  • Scotoma
  • Age Factors
  • Neuronal Plasticity
  • Visual Fields
  • Models, Neurological
  • Computer Simulation
Sprache
eng
Medium
Print
Paginierung
445 - 451
Datum der Veröffentlichung
2001
Status
Published
Datum der Datenerfassung
2001
Titel
Simulation of plasticity in the adult visual cortex.
Sub types
  • Research Support, Non-U.S. Gov't
  • Journal Article
Ausgabe der Zeitschrift
84

Data source: Europe PubMed Central

Abstract
Retinal plasticity has been shown in the adult visual nervous system in mammals. Following a retinal lesion (scotoma) there is a reorganization of the cortical receptive field distribution: cortical neurons selective to visual stimuli in the area of the visual field corresponding to the retinal lesion, become selective to other parts of the visual field. In this work, we study this effect with a self-organizing neural network. In a first stage, the network reaches a pattern of connectivity that represents normal development of neuronal selectivity. The scotoma is simulated by perturbing accordingly the properties of a region of the input layer representing the retina. The system evolves to a new receptive field distribution mainly by means of the reorganization of the intra cortical connectivity. No major change of the geniculo cortical connectivity is detected. This may explain the surprisingly short time scale of the event.
Autoren
  • MA Andrade
  • EM Muro
  • F Morán
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/11417056
DOI
10.1007/PL00007988
ISSN
0340-1200
Ausgabe der Veröffentlichung
6
Zeitschrift
Biol Cybern
Schlüsselwörter
  • Age Factors
  • Animals
  • Computer Simulation
  • Mammals
  • Models, Neurological
  • Neuronal Plasticity
  • Scotoma
  • Visual Cortex
  • Visual Fields
Sprache
eng
Country
Germany
Paginierung
445 - 451
Datum der Veröffentlichung
2001
Status
Published
Datum, an dem der Datensatz öffentlich gemacht wurde
2001
Titel
Simulation of plasticity in the adult visual cortex.
Sub types
  • Journal Article
  • Research Support, Non-U.S. Gov't
Ausgabe der Zeitschrift
84

Data source: PubMed

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