Early Neolithic genomes from the eastern Fertile Crescent

Autoren

Farnaz Broushaki
Mark G Thomas
Vivian Link
Saioa Lopez
Lucy van Dorp
Karola Kirsanow
Zuzana Hofmanova
Yoan Diekmann
Lara M Cassidy
David Diez-del-Molino
Athanasios Kousathanas
Christian Sell
Harry K Robson
Rui Martiniano
Jens Bloecher
Amelie Scheu
Susanne Kreutzer
Ruth Bollongino
Dean Bobo
Hossein Davoudi
Olivia Munoz
Mathias Currat
Kamyar Abdi
Fereidoun Biglari
Oliver E Craig
Daniel G Bradley
Stephen Shennan
Krishna R Veeramah
Marjan Mashkour
Daniel Wegmann
Garrett Hellenthal
Joachim Burger

Autoren-URL

https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000380583600044&DestLinkType=FullRecord&DestApp=WOS_CPL

DOI

10.1126/science.aaf7943

eISSN

1095-9203

Externe Identifier

Clarivate Analytics Document Solution ID: DS2HC
PubMed Identifier: 27417496

ISSN

0036-8075

Ausgabe der Veröffentlichung

6298

Zeitschrift

SCIENCE

Paginierung

499 - 503

Datum der Veröffentlichung

2016

Status

Published

Titel

Early Neolithic genomes from the eastern Fertile Crescent

Sub types

Article

Ausgabe der Zeitschrift

353

Data source: Web of Science (Lite)

Abstract

Near Eastern genomes from Iran The genetic composition of populations in Europe changed during the Neolithic transition from hunting and gathering to farming. To better understand the origin of modern populations, Broushaki et al. sequenced ancient DNA from four individuals from the Zagros region of present-day Iran, representing the early Neolithic Fertile Crescent. These individuals unexpectedly were not ancestral to early European farmers, and their genetic structures did not contribute significantly to those of present-day Europeans. These data indicate that a parallel Neolithic transition probably resulted from structured farming populations across southwest Asia. Science , this issue p. 499

Autoren

Farnaz Broushaki
Mark G Thomas
Vivian Link
Saioa López
Lucy van Dorp
Karola Kirsanow
Zuzana Hofmanová
Yoan Diekmann
Lara M Cassidy
David Díez-del-Molino
Athanasios Kousathanas
Christian Sell
Harry K Robson
Rui Martiniano
Jens Blöcher
Amelie Scheu
Susanne Kreutzer
Ruth Bollongino
Dean Bobo
Hossein Davoudi
Olivia Munoz
Mathias Currat
Kamyar Abdi
Fereidoun Biglari
Oliver E Craig
Daniel G Bradley
Stephen Shennan
Krishna R Veeramah
Marjan Mashkour
Daniel Wegmann
Garrett Hellenthal
Joachim Burger

DOI

10.1126/science.aaf7943

eISSN

1095-9203

ISSN

0036-8075

Ausgabe der Veröffentlichung

6298

Zeitschrift

Science

Sprache

en

Paginierung

499 - 503

Datum der Veröffentlichung

2016

Status

Published

Herausgeber

American Association for the Advancement of Science (AAAS)

Herausgeber URL

http://dx.doi.org/10.1126/science.aaf7943

Datum der Datenerfassung

2024

Titel

Early Neolithic genomes from the eastern Fertile Crescent

Ausgabe der Zeitschrift

353

Data source: Crossref

Abstract

We sequenced Early Neolithic genomes from the Zagros region of Iran (eastern Fertile Crescent), where some of the earliest evidence for farming is found, and identify a previously uncharacterized population that is neither ancestral to the first European farmers nor has contributed substantially to the ancestry of modern Europeans. These people are estimated to have separated from Early Neolithic farmers in Anatolia some 46,000 to 77,000 years ago and show affinities to modern-day Pakistani and Afghan populations, but particularly to Iranian Zoroastrians. We conclude that multiple, genetically differentiated hunter-gatherer populations adopted farming in southwestern Asia, that components of pre-Neolithic population structure were preserved as farming spread into neighboring regions, and that the Zagros region was the cradle of eastward expansion.

Addresses

Palaeogenetics Group, Johannes Gutenberg University Mainz, 55099 Mainz, Germany.

Autoren

Farnaz Broushaki
Mark G Thomas
Vivian Link
Saioa López
Lucy van Dorp
Karola Kirsanow
Zuzana Hofmanová
Yoan Diekmann
Lara M Cassidy
David Díez-Del-Molino
Athanasios Kousathanas
Christian Sell
Harry K Robson
Rui Martiniano
Jens Blöcher
Amelie Scheu
Susanne Kreutzer
Ruth Bollongino
Dean Bobo
Hossein Davudi
Olivia Munoz
Mathias Currat
Kamyar Abdi
Fereidoun Biglari
Oliver E Craig
Daniel G Bradley
Stephen Shennan
Krishna Veeramah
Marjan Mashkour
Daniel Wegmann
Garrett Hellenthal
Joachim Burger

DOI

10.1126/science.aaf7943

eISSN

1095-9203

Externe Identifier

PubMed Identifier: 27417496
PubMed Central ID: PMC5113750

Funding acknowledgements

Wellcome Trust:
Biotechnology and Biological Sciences Research Council: BB/L009382/1
Wellcome Trust Senior Research Fellowship:
INST: 247/602-1 FUGG
Swiss NSF: 31003A_149920
Swiss NSF: 31003A_156853
National Institute for Health Research University College London Hospitals Biomedical Research Centre:
DFG:
Wellcome Trust: 098386
Royal Society: 098386/Z/12/Z
Wellcome Trust: 100719/Z/12/Z
Wellcome Trust: 098386/Z/12/Z
Deutsche Forschungsgemeinschaft (DFG): BO 4119/1
Engineering and Physical Sciences Research Council: EP/F500351/1
Irish Research Council: GOIPG/2013/1219
National Institute for Health Research (NIHR):

Open access

false

ISSN

0036-8075

Ausgabe der Veröffentlichung

6298

Zeitschrift

Science (New York, N.Y.)

Schlüsselwörter

Humans
Genome, Human
Agriculture
History, Ancient
Afghanistan
Iran
Pakistan
Genetic Variation
Human Migration
Ethnicity
White People

Sprache

eng

Medium

Print-Electronic

Online publication date

2016

Paginierung

499 - 503

Datum der Veröffentlichung

2016

Status

Published

Datum der Datenerfassung

2016

Titel

Early Neolithic genomes from the eastern Fertile Crescent.

Sub types

Historical Article
Research Support, Non-U.S. Gov't
research-article
Journal Article

Ausgabe der Zeitschrift

353

Files

https://science.sciencemag.org/content/sci/353/6298/499.full.pdf https://europepmc.org/articles/PMC5113750?pdf=render

Data source: Europe PubMed Central

Abstract

We sequenced Early Neolithic genomes from the Zagros region of Iran (eastern Fertile Crescent), where some of the earliest evidence for farming is found, and identify a previously uncharacterized population that is neither ancestral to the first European farmers nor has contributed substantially to the ancestry of modern Europeans. These people are estimated to have separated from Early Neolithic farmers in Anatolia some 46,000 to 77,000 years ago and show affinities to modern-day Pakistani and Afghan populations, but particularly to Iranian Zoroastrians. We conclude that multiple, genetically differentiated hunter-gatherer populations adopted farming in southwestern Asia, that components of pre-Neolithic population structure were preserved as farming spread into neighboring regions, and that the Zagros region was the cradle of eastward expansion.

Date of acceptance

2016

Autoren

Farnaz Broushaki
Mark G Thomas
Vivian Link
Saioa López
Lucy van Dorp
Karola Kirsanow
Zuzana Hofmanová
Yoan Diekmann
Lara M Cassidy
David Díez-Del-Molino
Athanasios Kousathanas
Christian Sell
Harry K Robson
Rui Martiniano
Jens Blöcher
Amelie Scheu
Susanne Kreutzer
Ruth Bollongino
Dean Bobo
Hossein Davudi
Olivia Munoz
Mathias Currat
Kamyar Abdi
Fereidoun Biglari
Oliver E Craig
Daniel G Bradley
Stephen Shennan
Krishna Veeramah
Marjan Mashkour
Daniel Wegmann
Garrett Hellenthal
Joachim Burger

Autoren-URL

https://www.ncbi.nlm.nih.gov/pubmed/27417496

DOI

10.1126/science.aaf7943

eISSN

1095-9203

Externe Identifier

NIH Manuscript Submission ID: EMS70186
PubMed Central ID: PMC5113750

Funding acknowledgements

Wellcome Trust: 098386
Wellcome Trust: 098386/Z/12/Z
Biotechnology and Biological Sciences Research Council: BB/L009382/1
Department of Health:

Ausgabe der Veröffentlichung

6298

Zeitschrift

Science

Schlüsselwörter

Afghanistan
Agriculture
Ethnicity
Genetic Variation
Genome, Human
History, Ancient
Human Migration
Humans
Iran
Pakistan
White People

Sprache

eng

Country

United States

Paginierung

499 - 503

Datum der Veröffentlichung

2016

Status

Published

Datum, an dem der Datensatz öffentlich gemacht wurde

2016

Titel

Early Neolithic genomes from the eastern Fertile Crescent.

Sub types

Historical Article
Journal Article
Research Support, Non-U.S. Gov't

Ausgabe der Zeitschrift

353

Data source: PubMed

Author's licence

InCopyright

Autoren

Farnaz Broushaki
Mark G Thomas
Vivian Link
Saioa López
Lucy van Dorp
Karola Kirsanow
Zuzana Hofmanová
Yoan Diekmann
Lara M Cassidy
David Díez-del-Molino
Athanasios Kousathanas
Christian Sell
Harry K Robson
Rui Martiniano
Jens Blöcher
Amelie Scheu
Susanne Kreutzer
Ruth Bollongino
Dean Bobo
Hossein Davoudi
Olivia Munoz
Mathias Currat
Kamyar Abdi
Fereidoun Biglari
Oliver E Craig
Daniel G Bradley
Stephen Shennan
Krishna R Veeramah
Marjan Mashkour
Daniel Wegmann
Garrett Hellenthal
Joachim Burger

Hosting institution

Universitätsbibliothek Mainz

Sammlungen

DFG-OA-Publizieren (2012 - 2017)

Resource version

Published version

DOI

10.1126/science.aaf7943

Funding acknowledgements

DFG, Open Access-Publizieren Universität Mainz / Universitätsmedizin

File(s) embargoed

false

Open access

true

ISSN

0036-8075

Ausgabe der Veröffentlichung

6298

Zeitschrift

Science

Schlüsselwörter

570 Biowissenschaften
570 Life sciences

Sprache

eng

Open access status

Open Access

Paginierung

499 - 503

Datum der Veröffentlichung

2016

Public URL

https://openscience.ub.uni-mainz.de/handle/20.500.12030/8510

Herausgeber

American Association for the Advancement of Science

Herausgeber URL

http://dx.doi.org/10.1126/science.aaf7943

Datum der Datenerfassung

2022

Datum, an dem der Datensatz öffentlich gemacht wurde

2022

Zugang

Public

Titel

Early Neolithic genomes from the eastern Fertile Crescent

Ausgabe der Zeitschrift

353

Files

early_neolithic_genomes_from_-20220925175801112.pdf

Data source: OPENSCIENCE.UB

Early Neolithic genomes from the eastern Fertile Crescent

Files

Files

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