Lipid Carbonyl Groups Terminate the Hydrogen Bond Network of Membrane-Bound Water

Publication type:
Journal article
Metadata:
Autoren
  • Tatsuhiko Ohto
  • Ellen HG Backus
  • Cho-Shuen Hsieh
  • Marialore Sulpizi
  • Mischa Bonn
  • Yuki Nagata
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000365460700009&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.1021/acs.jpclett.5b02141
Externe Identifier
  • Clarivate Analytics Document Solution ID: CX1MQ
  • PubMed Identifier: 26506078
ISSN
1948-7185
Ausgabe der Veröffentlichung
22
Zeitschrift
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
Paginierung
4499 - 4503
Datum der Veröffentlichung
2015
Status
Published
Titel
Lipid Carbonyl Groups Terminate the Hydrogen Bond Network of Membrane-Bound Water
Sub types
  • Article
Ausgabe der Zeitschrift
6

Data source: Web of Science (Lite)

Other metadata sources:
Autoren
  • Tatsuhiko Ohto
  • Ellen HG Backus
  • Cho-Shuen Hsieh
  • Marialore Sulpizi
  • Mischa Bonn
  • Yuki Nagata
DOI
10.1021/acs.jpclett.5b02141
eISSN
1948-7185
ISSN
1948-7185
Ausgabe der Veröffentlichung
22
Zeitschrift
The Journal of Physical Chemistry Letters
Sprache
en
Online publication date
2015
Paginierung
4499 - 4503
Datum der Veröffentlichung
2015
Status
Published
Herausgeber
American Chemical Society (ACS)
Herausgeber URL
http://dx.doi.org/10.1021/acs.jpclett.5b02141
Datum der Datenerfassung
2023
Titel
Lipid Carbonyl Groups Terminate the Hydrogen Bond Network of Membrane-Bound Water
Ausgabe der Zeitschrift
6

Data source: Crossref

Abstract
We present a combined experimental sum-frequency generation (SFG) spectroscopy and ab initio molecular dynamics simulations study to clarify the structure and orientation of water at zwitterionic phosphatidylcholine (PC) lipid and amine N-oxide (AO) surfactant monolayers. Simulated O-H stretch SFG spectra of water show good agreement with the experimental data. The SFG response at the PC interface exhibits positive peaks, whereas both negative and positive bands are present for the similar zwitterionic AO interface. The positive peaks at the water/PC interface are attributed to water interacting with the lipid carbonyl groups, which act as efficient hydrogen bond acceptors. This allows the water hydrogen bond network to reach, with its (up-oriented) O-H groups, into the headgroup of the lipid, a mechanism not available for water underneath the AO surfactant. This highlights the role of the lipid carbonyl group in the interfacial water structure at the membrane interface, namely, stabilizing the water hydrogen bond network.
Addresses
  • Max-Planck Institute for Polymer Research , Ackermannweg 10, 55128 Mainz, Germany.
Autoren
  • Tatsuhiko Ohto
  • Ellen HG Backus
  • Cho-Shuen Hsieh
  • Marialore Sulpizi
  • Mischa Bonn
  • Yuki Nagata
DOI
10.1021/acs.jpclett.5b02141
eISSN
1948-7185
Externe Identifier
  • PubMed Identifier: 26506078
Funding acknowledgements
  • Ministry of Education, Culture, Sports, Science, and Technology: 26104522
  • Deutsche Forschungsgemeinschaft: TRR 146
Open access
false
ISSN
1948-7185
Ausgabe der Veröffentlichung
22
Zeitschrift
The journal of physical chemistry letters
Schlüsselwörter
  • Membranes
  • Water
  • Lipids
  • Phosphatidylcholines
  • Hydrogen Bonding
  • Molecular Dynamics Simulation
Sprache
eng
Medium
Print-Electronic
Online publication date
2015
Paginierung
4499 - 4503
Datum der Veröffentlichung
2015
Status
Published
Datum der Datenerfassung
2015
Titel
Lipid carbonyl groups terminate the hydrogen bond network of membrane-bound water.
Sub types
  • Research Support, Non-U.S. Gov't
  • Journal Article
Ausgabe der Zeitschrift
6

Data source: Europe PubMed Central

Abstract
We present a combined experimental sum-frequency generation (SFG) spectroscopy and ab initio molecular dynamics simulations study to clarify the structure and orientation of water at zwitterionic phosphatidylcholine (PC) lipid and amine N-oxide (AO) surfactant monolayers. Simulated O-H stretch SFG spectra of water show good agreement with the experimental data. The SFG response at the PC interface exhibits positive peaks, whereas both negative and positive bands are present for the similar zwitterionic AO interface. The positive peaks at the water/PC interface are attributed to water interacting with the lipid carbonyl groups, which act as efficient hydrogen bond acceptors. This allows the water hydrogen bond network to reach, with its (up-oriented) O-H groups, into the headgroup of the lipid, a mechanism not available for water underneath the AO surfactant. This highlights the role of the lipid carbonyl group in the interfacial water structure at the membrane interface, namely, stabilizing the water hydrogen bond network.
Autoren
  • Tatsuhiko Ohto
  • Ellen HG Backus
  • Cho-Shuen Hsieh
  • Marialore Sulpizi
  • Mischa Bonn
  • Yuki Nagata
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/26506078
DOI
10.1021/acs.jpclett.5b02141
eISSN
1948-7185
Ausgabe der Veröffentlichung
22
Zeitschrift
J Phys Chem Lett
Schlüsselwörter
  • amine N-oxide
  • hydrogen bond network
  • interfacial water
  • phosphatidylcholine
  • sum-frequency generation spectroscopy
  • Hydrogen Bonding
  • Lipids
  • Membranes
  • Molecular Dynamics Simulation
  • Phosphatidylcholines
  • Water
Sprache
eng
Country
United States
Paginierung
4499 - 4503
Datum der Veröffentlichung
2015
Status
Published
Datum, an dem der Datensatz öffentlich gemacht wurde
2016
Titel
Lipid carbonyl groups terminate the hydrogen bond network of membrane-bound water.
Sub types
  • Journal Article
  • Research Support, Non-U.S. Gov't
Ausgabe der Zeitschrift
6

Data source: PubMed

Beziehungen:
Property of

Tools