In Silico Design Enables the Rapid Production of Surface-Active Colloidal Amphiphiles
- Publication type:
- Journal article
- Metadata:
-
- Autoren
- Tatiana I Morozova
- Victoria Lee
- Navid Bizmark
- Sujit S Datta
- Robert K Prud'homme
- Arash Nikoubashman
- Rodney D Priestley
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000517832800011&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1021/acscentsci.9b00974
- eISSN
- 2374-7951
- Externe Identifier
- Clarivate Analytics Document Solution ID: KR7YK
- PubMed Identifier: 32123734
- ISSN
- 2374-7943
- Ausgabe der Veröffentlichung
- 2
- Zeitschrift
- ACS CENTRAL SCIENCE
- Paginierung
- 166 - 173
- Datum der Veröffentlichung
- 2020
- Status
- Published
- Titel
- In Silico Design Enables the Rapid Production of Surface-Active Colloidal Amphiphiles
- Sub types
- Article
- Ausgabe der Zeitschrift
- 6
Data source: Web of Science (Lite)
- Other metadata sources:
-
- Autoren
- Tatiana I Morozova
- Victoria E Lee
- Navid Bizmark
- Sujit S Datta
- Robert K Prud’homme
- Arash Nikoubashman
- Rodney D Priestley
- DOI
- 10.1021/acscentsci.9b00974
- eISSN
- 2374-7951
- ISSN
- 2374-7943
- Ausgabe der Veröffentlichung
- 2
- Zeitschrift
- ACS Central Science
- Sprache
- en
- Online publication date
- 2020
- Paginierung
- 166 - 173
- Datum der Veröffentlichung
- 2020
- Status
- Published
- Herausgeber
- American Chemical Society (ACS)
- Herausgeber URL
- http://dx.doi.org/10.1021/acscentsci.9b00974
- Datum der Datenerfassung
- 2023
- Titel
- In Silico Design Enables the Rapid Production of Surface-Active Colloidal Amphiphiles
- Ausgabe der Zeitschrift
- 6
Data source: Crossref
- Abstract
- A new technology platform built on the integration of theory and experiments to enable the design of Janus colloids with precision control of surface anisotropy and amphiphilicity could lead to a disruptive transformation in the next generation of surfactants, photonic or phononic materials, and coatings. Here, we exploit molecular dynamics (MD) simulations to guide the rational design of amphiphilic polymer Janus colloids by Flash NanoPrecipitation (FNP), a method capable of the production of colloids with complex structure without the compromise of reduced scalability. Aided by in silico design, we show in experiments that amphiphilic Janus colloids can be produced using a unique blend of hydrophobic homopolymers and the addition of an amphiphilic block copolymer. The final structure of the colloids depends on the mass fraction of each homopolymer as well as the concentration and composition of the block copolymer additive. To confirm the surface activity of the colloids, we demonstrate their potential to stabilize Pickering emulsions. This hybrid approach of simulations and experiments provides a pathway to designing and manufacturing complex polymeric colloids on an industrial scale.
- Addresses
- Institute of Physics, Johannes Gutenberg University Mainz, Staudingerweg 7, 55128 Mainz, Germany.
- Autoren
- Tatiana I Morozova
- Victoria E Lee
- Navid Bizmark
- Sujit S Datta
- Robert K Prud'homme
- Arash Nikoubashman
- Rodney D Priestley
- DOI
- 10.1021/acscentsci.9b00974
- eISSN
- 2374-7951
- Externe Identifier
- PubMed Identifier: 32123734
- PubMed Central ID: PMC7047274
- Funding acknowledgements
- Division of Materials Research: DMR-1420541
- National Science Foundation: IIP - 1827506
- Deutsche Forschungsgemeinschaft: NI 1487/2-1
- Open access
- true
- ISSN
- 2374-7943
- Ausgabe der Veröffentlichung
- 2
- Zeitschrift
- ACS central science
- Sprache
- eng
- Medium
- Print-Electronic
- Online publication date
- 2020
- Open access status
- Open Access
- Paginierung
- 166 - 173
- Datum der Veröffentlichung
- 2020
- Status
- Published
- Datum der Datenerfassung
- 2020
- Titel
- In Silico Design Enables the Rapid Production of Surface-Active Colloidal Amphiphiles.
- Sub types
- research-article
- Journal Article
- Ausgabe der Zeitschrift
- 6
Files
https://pubs.acs.org/doi/pdf/10.1021/acscentsci.9b00974 https://europepmc.org/articles/PMC7047274?pdf=render
Data source: Europe PubMed Central
- Abstract
- A new technology platform built on the integration of theory and experiments to enable the design of Janus colloids with precision control of surface anisotropy and amphiphilicity could lead to a disruptive transformation in the next generation of surfactants, photonic or phononic materials, and coatings. Here, we exploit molecular dynamics (MD) simulations to guide the rational design of amphiphilic polymer Janus colloids by Flash NanoPrecipitation (FNP), a method capable of the production of colloids with complex structure without the compromise of reduced scalability. Aided by in silico design, we show in experiments that amphiphilic Janus colloids can be produced using a unique blend of hydrophobic homopolymers and the addition of an amphiphilic block copolymer. The final structure of the colloids depends on the mass fraction of each homopolymer as well as the concentration and composition of the block copolymer additive. To confirm the surface activity of the colloids, we demonstrate their potential to stabilize Pickering emulsions. This hybrid approach of simulations and experiments provides a pathway to designing and manufacturing complex polymeric colloids on an industrial scale.
- Autoren
- Tatiana I Morozova
- Victoria E Lee
- Navid Bizmark
- Sujit S Datta
- Robert K Prud'homme
- Arash Nikoubashman
- Rodney D Priestley
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/32123734
- DOI
- 10.1021/acscentsci.9b00974
- Externe Identifier
- PubMed Central ID: PMC7047274
- ISSN
- 2374-7943
- Ausgabe der Veröffentlichung
- 2
- Zeitschrift
- ACS Cent Sci
- Sprache
- eng
- Country
- United States
- Paginierung
- 166 - 173
- Datum der Veröffentlichung
- 2020
- Status
- Published
- Titel
- In Silico Design Enables the Rapid Production of Surface-Active Colloidal Amphiphiles.
- Sub types
- Journal Article
- Ausgabe der Zeitschrift
- 6
Data source: PubMed
- Beziehungen:
- Property of