Specific adhesion of membranes: Mapping to an effective bond lattice gas
- Publication type:
- Journal article
- Metadata:
-
- Autoren
- Thomas Speck
- Ellen Reister
- Udo Seifert
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000281296000007&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1103/PhysRevE.82.021923
- eISSN
- 1550-2376
- Externe Identifier
- Clarivate Analytics Document Solution ID: 643KT
- PubMed Identifier: 20866853
- ISSN
- 1539-3755
- Ausgabe der Veröffentlichung
- 2
- Zeitschrift
- PHYSICAL REVIEW E
- Artikelnummer
- ARTN 021923
- Datum der Veröffentlichung
- 2010
- Status
- Published
- Titel
- Specific adhesion of membranes: Mapping to an effective bond lattice gas
- Sub types
- Article
- Ausgabe der Zeitschrift
- 82
Data source: Web of Science (Lite)
- Other metadata sources:
-
- Autoren
- Thomas Speck
- Ellen Reister
- Udo Seifert
- DOI
- 10.1103/physreve.82.021923
- eISSN
- 1550-2376
- ISSN
- 1539-3755
- Ausgabe der Veröffentlichung
- 2
- Zeitschrift
- Physical Review E
- Sprache
- en
- Artikelnummer
- 021923
- Online publication date
- 2010
- Status
- Published online
- Herausgeber
- American Physical Society (APS)
- Herausgeber URL
- http://dx.doi.org/10.1103/physreve.82.021923
- Datum der Datenerfassung
- 2021
- Titel
- Specific adhesion of membranes: Mapping to an effective bond lattice gas
- Ausgabe der Zeitschrift
- 82
Data source: Crossref
- Abstract
- We theoretically consider specific adhesion of a fluctuating membrane to a hard substrate via the formation of bonds between receptors attached to the substrate and ligands in the membrane. By integrating out the degrees of freedom of the membrane shape, we show that in the biologically relevant limit specific adhesion is well described by a lattice gas model, where lattice sites correspond to bond sites. We derive an explicit expression for the effective bond interactions induced by the thermal undulations of the membrane. Furthermore, we compare kinetic Monte Carlo simulations for our lattice gas model with full dynamic simulations that take into account both the shape fluctuations of the membrane and reactions between receptors and ligands at bond sites. We demonstrate that an appropriate mapping of the height dependent binding and unbinding rates in the full scheme to rates in the lattice gas model leads to good agreement.
- Addresses
- Department of Chemistry, University of California, Berkeley, 94720, USA.
- Autoren
- Thomas Speck
- Ellen Reister
- Udo Seifert
- DOI
- 10.1103/physreve.82.021923
- eISSN
- 1550-2376
- Externe Identifier
- PubMed Identifier: 20866853
- Open access
- false
- ISSN
- 1539-3755
- Ausgabe der Veröffentlichung
- 2 Pt 1
- Zeitschrift
- Physical review. E, Statistical, nonlinear, and soft matter physics
- Schlüsselwörter
- Cell Membrane
- Gases
- Membrane Proteins
- Protein Binding
- Adhesiveness
- Models, Chemical
- Computer Simulation
- Sprache
- eng
- Medium
- Print-Electronic
- Online publication date
- 2010
- Paginierung
- 021923
- Datum der Veröffentlichung
- 2010
- Status
- Published
- Datum der Datenerfassung
- 2010
- Titel
- Specific adhesion of membranes: Mapping to an effective bond lattice gas.
- Sub types
- Research Support, Non-U.S. Gov't
- Research Support, U.S. Gov't, Non-P.H.S.
- Journal Article
- Ausgabe der Zeitschrift
- 82
Data source: Europe PubMed Central
- Abstract
- We theoretically consider specific adhesion of a fluctuating membrane to a hard substrate via the formation of bonds between receptors attached to the substrate and ligands in the membrane. By integrating out the degrees of freedom of the membrane shape, we show that in the biologically relevant limit specific adhesion is well described by a lattice gas model, where lattice sites correspond to bond sites. We derive an explicit expression for the effective bond interactions induced by the thermal undulations of the membrane. Furthermore, we compare kinetic Monte Carlo simulations for our lattice gas model with full dynamic simulations that take into account both the shape fluctuations of the membrane and reactions between receptors and ligands at bond sites. We demonstrate that an appropriate mapping of the height dependent binding and unbinding rates in the full scheme to rates in the lattice gas model leads to good agreement.
- Autoren
- Thomas Speck
- Ellen Reister
- Udo Seifert
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/20866853
- DOI
- 10.1103/PhysRevE.82.021923
- eISSN
- 1550-2376
- Ausgabe der Veröffentlichung
- 2 Pt 1
- Zeitschrift
- Phys Rev E Stat Nonlin Soft Matter Phys
- Schlüsselwörter
- Adhesiveness
- Cell Membrane
- Computer Simulation
- Gases
- Membrane Proteins
- Models, Chemical
- Protein Binding
- Sprache
- eng
- Country
- United States
- Paginierung
- 021923
- Datum der Veröffentlichung
- 2010
- Status
- Published
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2011
- Titel
- Specific adhesion of membranes: Mapping to an effective bond lattice gas.
- Sub types
- Journal Article
- Research Support, Non-U.S. Gov't
- Research Support, U.S. Gov't, Non-P.H.S.
- Ausgabe der Zeitschrift
- 82
Data source: PubMed
- Abstract
- We theoretically consider specific adhesion of a fluctuating membrane to a hard substrate via the formation of bonds between receptors attached to the substrate and ligands in the membrane. By integrating out the degrees of freedom of the membrane shape, we show that in the biologically relevant limit specific adhesion is well described by a lattice gas model, where lattice sites correspond to bond sites. We derive an explicit expression for the effective bond interactions induced by the thermal undulations of the membrane. Furthermore, we compare kinetic Monte Carlo simulations for our lattice gas model with full dynamic simulations that take into account both the shape fluctuations of the membrane and reactions between receptors and ligands at bond sites. We demonstrate that an appropriate mapping of the height dependent binding and unbinding rates in the full scheme to rates in the lattice gas model leads to good agreement.
- Autoren
- Thomas Speck
- Ellen Reister
- Udo Seifert
- Autoren-URL
- http://arxiv.org/abs/1004.2696v1
- Zeitschrift
- Phys. Rev. E
- Schlüsselwörter
- cond-mat.soft
- cond-mat.soft
- cond-mat.stat-mech
- Paginierung
- 021923
- Datum der Veröffentlichung
- 2010
- Herausgeber URL
- http://dx.doi.org/10.1103/PhysRevE.82.021923
- Datum der Datenerfassung
- 2010
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2010
- Titel
- Specific Adhesion of Membranes: Mapping to an Effective Bond Lattice Gas
- Ausgabe der Zeitschrift
- 82
Files
1004.2696v1.pdf
Data source: arXiv
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