Carbon fragmentation measurements and validation of the GEANT4 nuclear reaction models for hadrontherapy

Autoren

M De Napoli
C Agodi
G Battistoni
AA Blancato
GAP Cirrone
G Cuttone
F Giacoppo
MC Morone
D Nicolosi
L Pandola
V Patera
G Raciti
E Rapisarda
F Romano
D Sardina
A Sarti
A Sciubba
V Scuderi
C Sfienti
S Tropea

DOI

10.1088/0031-9155/57/22/7651

eISSN

1361-6560

ISSN

0031-9155

Ausgabe der Veröffentlichung

22

Zeitschrift

Physics in Medicine and Biology

Online publication date

2012

Paginierung

7651 - 7671

Datum der Veröffentlichung

2012

Status

Published

Herausgeber

IOP Publishing

Herausgeber URL

http://dx.doi.org/10.1088/0031-9155/57/22/7651

Datum der Datenerfassung

2020

Titel

Carbon fragmentation measurements and validation of the Geant4 nuclear reaction models for hadrontherapy

Ausgabe der Zeitschrift

57

Data source: Crossref

Abstract

Nuclear fragmentation measurements are necessary when using heavy-ion beams in hadrontherapy to predict the effects of the ion nuclear interactions within the human body. Moreover, they are also fundamental to validate and improve the Monte Carlo codes for their use in planning tumor treatments. Nowadays, a very limited set of carbon fragmentation cross sections are being measured, and in particular, to our knowledge, no double-differential fragmentation cross sections at intermediate energies are available in the literature. In this work, we have measured the double-differential cross sections and the angular distributions of the secondary fragments produced in the (12)C fragmentation at 62 A MeV on a thin carbon target. The experimental data have been used to benchmark the prediction capability of the Geant4 Monte Carlo code at intermediate energies, where it was never tested before. In particular, we have compared the experimental data with the predictions of two Geant4 nuclear reaction models: the Binary Light Ions Cascade and the Quantum Molecular Dynamic. From the comparison, it has been observed that the Binary Light Ions Cascade approximates the angular distributions of the fragment production cross sections better than the Quantum Molecular Dynamic model. However, the discrepancies observed between the experimental data and the Monte Carlo simulations lead to the conclusion that the prediction capability of both models needs to be improved at intermediate energies.

Addresses

INFN-Sezione di Catania, Catania, Italy. marzio.denapoli@ct.infn.it

Autoren

M De Napoli
C Agodi
G Battistoni
AA Blancato
GAP Cirrone
G Cuttone
F Giacoppo
MC Morone
D Nicolosi
L Pandola
V Patera
G Raciti
E Rapisarda
F Romano
D Sardina
A Sarti
A Sciubba
V Scuderi
C Sfienti
S Tropea

DOI

10.1088/0031-9155/57/22/7651

eISSN

1361-6560

Externe Identifier

PubMed Identifier: 23123643

Open access

false

ISSN

0031-9155

Ausgabe der Veröffentlichung

22

Zeitschrift

Physics in medicine and biology

Schlüsselwörter

Humans
Carbon
Monte Carlo Method
Heavy Ion Radiotherapy

Sprache

eng

Medium

Print-Electronic

Online publication date

2012

Paginierung

7651 - 7671

Datum der Veröffentlichung

2012

Status

Published

Datum der Datenerfassung

2012

Titel

Carbon fragmentation measurements and validation of the Geant4 nuclear reaction models for hadrontherapy.

Sub types

Research Support, Non-U.S. Gov't
Validation Study
Journal Article

Ausgabe der Zeitschrift

57

Data source: Europe PubMed Central

Abstract

Nuclear fragmentation measurements are necessary when using heavy-ion beams in hadrontherapy to predict the effects of the ion nuclear interactions within the human body. Moreover, they are also fundamental to validate and improve the Monte Carlo codes for their use in planning tumor treatments. Nowadays, a very limited set of carbon fragmentation cross sections are being measured, and in particular, to our knowledge, no double-differential fragmentation cross sections at intermediate energies are available in the literature. In this work, we have measured the double-differential cross sections and the angular distributions of the secondary fragments produced in the (12)C fragmentation at 62 A MeV on a thin carbon target. The experimental data have been used to benchmark the prediction capability of the Geant4 Monte Carlo code at intermediate energies, where it was never tested before. In particular, we have compared the experimental data with the predictions of two Geant4 nuclear reaction models: the Binary Light Ions Cascade and the Quantum Molecular Dynamic. From the comparison, it has been observed that the Binary Light Ions Cascade approximates the angular distributions of the fragment production cross sections better than the Quantum Molecular Dynamic model. However, the discrepancies observed between the experimental data and the Monte Carlo simulations lead to the conclusion that the prediction capability of both models needs to be improved at intermediate energies.

Autoren

M De Napoli
C Agodi
G Battistoni
AA Blancato
GAP Cirrone
G Cuttone
F Giacoppo
MC Morone
D Nicolosi
L Pandola
V Patera
G Raciti
E Rapisarda
F Romano
D Sardina
A Sarti
A Sciubba
V Scuderi
C Sfienti
S Tropea

Autoren-URL

https://www.ncbi.nlm.nih.gov/pubmed/23123643

DOI

10.1088/0031-9155/57/22/7651

eISSN

1361-6560

Ausgabe der Veröffentlichung

22

Zeitschrift

Phys Med Biol

Schlüsselwörter

Carbon
Heavy Ion Radiotherapy
Humans
Monte Carlo Method

Sprache

eng

Country

England

Paginierung

7651 - 7671

Datum der Veröffentlichung

2012

Status

Published

Datum, an dem der Datensatz öffentlich gemacht wurde

2013

Titel

Carbon fragmentation measurements and validation of the Geant4 nuclear reaction models for hadrontherapy.

Sub types

Journal Article
Research Support, Non-U.S. Gov't
Validation Study

Ausgabe der Zeitschrift

57

Data source: PubMed

Carbon fragmentation measurements and validation of the GEANT4 nuclear reaction models for hadrontherapy

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