Silica-coated Au@ZnO Janus particles and their stability in epithelial cells
- Publication type:
- Journal article
- Metadata:
-
- Autoren
- Moritz Susewind
- Anna-Maria Schilmann
- Julia Heim
- Andreas Henkel
- Thorben Link
- Karl Fischer
- Dennis Strand
- Ute Kolb
- Muhammad Nawaz Tahir
- Jürgen Brieger
- Wolfgang Tremel
- Sammlungen
- metadata
- ISSN
- 2050-750X
- Ausgabe der Veröffentlichung
- 9
- Zeitschrift
- Journal of materials chemistry : B
- Schlüsselwörter
- 540 Chemie
- 540 Chemistry and allied sciences
- Paginierung
- Seiten: 1813 - 1822
- Datum der Veröffentlichung
- 2015
- Herausgeber
- The Royal Society of Chemistry
- Herausgeber URL
- http://dx.doi.org/10.1039/C4TB02017K
- Datum der Datenerfassung
- 2020
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2020
- Zugang
- Public
- Titel
- Silica-coated Au@ZnO Janus particles and their stability in epithelial cells
- Ausgabe der Zeitschrift
- 3
Data source: METADATA.UB
- Other metadata sources:
-
- Autoren
- Moritz Susewind
- Anna-Maria Schilmann
- Julia Heim
- Andreas Henkel
- Thorben Link
- Karl Fischer
- Dennis Strand
- Ute Kolb
- Muhammad Nawaz Tahir
- Urgen Brieger
- Wolfgang Tremel
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000350343700008&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1039/c4tb02017k
- eISSN
- 2050-7518
- Externe Identifier
- Clarivate Analytics Document Solution ID: CC4SM
- PubMed Identifier: 32262254
- ISSN
- 2050-750X
- Ausgabe der Veröffentlichung
- 9
- Zeitschrift
- JOURNAL OF MATERIALS CHEMISTRY B
- Paginierung
- 1813 - 1822
- Datum der Veröffentlichung
- 2015
- Status
- Published
- Titel
- Silica-coated Au@ZnO Janus particles and their stability in epithelial cells
- Sub types
- Article
- Ausgabe der Zeitschrift
- 3
Data source: Web of Science (Lite)
- Abstract
- <p>Multicomponent particles have emerged in recent years as new compartmentalized colloids with two sides of different chemistry or polarity that have opened up a wide field of unique applications in medicine, physics and chemistry.</p>
- Autoren
- Moritz Susewind
- Anna-Maria Schilmann
- Julia Heim
- Andreas Henkel
- Thorben Link
- Karl Fischer
- Dennis Strand
- Ute Kolb
- Muhammad Nawaz Tahir
- Jürgen Brieger
- Wolfgang Tremel
- DOI
- 10.1039/c4tb02017k
- eISSN
- 2050-7518
- ISSN
- 2050-750X
- Ausgabe der Veröffentlichung
- 9
- Zeitschrift
- Journal of Materials Chemistry B
- Sprache
- en
- Online publication date
- 2015
- Paginierung
- 1813 - 1822
- Status
- Published online
- Herausgeber
- Royal Society of Chemistry (RSC)
- Herausgeber URL
- http://dx.doi.org/10.1039/c4tb02017k
- Datum der Datenerfassung
- 2024
- Titel
- Silica-coated Au@ZnO Janus particles and their stability in epithelial cells
- Ausgabe der Zeitschrift
- 3
Data source: Crossref
- Abstract
- Multicomponent particles have emerged in recent years as new compartmentalized colloids with two sides of different chemistry or polarity that have opened up a wide field of unique applications in medicine, biochemistry, optics, physics and chemistry. A drawback of particles containing a ZnO hemisphere is their low stability in biological environment due to the amphoteric properties of Zn<sup>2+</sup>. Therefore we have synthesized monodisperse Au@ZnO Janus particles by seed-mediated nucleation and growth whose ZnO domain was coated selectively with a thin SiO<sub>2</sub> layer as a protection from the surrounding environment that imparts stability in aqueous media while the Au domain remained untouched. The thickness of the SiO<sub>2</sub> layer could be precisely controlled. The SiO<sub>2</sub> coating of the oxide domain allows biomolecule conjugation (e.g. antibodies, proteins) in a single step for converting the photoluminescent and photocatalytic active Janus nanoparticles into multifunctional efficient vehicles for cell targeting. The SiO<sub>2</sub>-coated functionalized nanoparticles were stable in buffer solutions and other aqueous systems. Biocompatibility and potential biomedical applications of the Au@ZnO@SiO<sub>2</sub> Janus particles were assayed by a cell viability analysis by co-incubating the Au@ZnO@SiO<sub>2</sub> Janus particles with epithelia cells and compared to those of uncoated ZnO.
- Addresses
- Institut für Anorganische Chemie und Analytische Chemie, Johannes Gutenberg-Universität, Duesbergweg 10-14, D-55099 Mainz, Germany. tremel@uni-mainz.de tahir@uni-mainz.de.
- Autoren
- Moritz Susewind
- Anna-Maria Schilmann
- Julia Heim
- Andreas Henkel
- Thorben Link
- Karl Fischer
- Dennis Strand
- Ute Kolb
- Muhammad Nawaz Tahir
- Jürgen Brieger
- Wolfgang Tremel
- DOI
- 10.1039/c4tb02017k
- eISSN
- 2050-7518
- Externe Identifier
- PubMed Identifier: 32262254
- Open access
- false
- ISSN
- 2050-750X
- Ausgabe der Veröffentlichung
- 9
- Zeitschrift
- Journal of materials chemistry. B
- Sprache
- eng
- Medium
- Print-Electronic
- Online publication date
- 2015
- Paginierung
- 1813 - 1822
- Datum der Veröffentlichung
- 2015
- Status
- Published
- Datum der Datenerfassung
- 2020
- Titel
- Silica-coated Au@ZnO Janus particles and their stability in epithelial cells.
- Sub types
- Journal Article
- Ausgabe der Zeitschrift
- 3
Data source: Europe PubMed Central
- Abstract
- Multicomponent particles have emerged in recent years as new compartmentalized colloids with two sides of different chemistry or polarity that have opened up a wide field of unique applications in medicine, biochemistry, optics, physics and chemistry. A drawback of particles containing a ZnO hemisphere is their low stability in biological environment due to the amphoteric properties of Zn2+. Therefore we have synthesized monodisperse Au@ZnO Janus particles by seed-mediated nucleation and growth whose ZnO domain was coated selectively with a thin SiO2 layer as a protection from the surrounding environment that imparts stability in aqueous media while the Au domain remained untouched. The thickness of the SiO2 layer could be precisely controlled. The SiO2 coating of the oxide domain allows biomolecule conjugation (e.g. antibodies, proteins) in a single step for converting the photoluminescent and photocatalytic active Janus nanoparticles into multifunctional efficient vehicles for cell targeting. The SiO2-coated functionalized nanoparticles were stable in buffer solutions and other aqueous systems. Biocompatibility and potential biomedical applications of the Au@ZnO@SiO2 Janus particles were assayed by a cell viability analysis by co-incubating the Au@ZnO@SiO2 Janus particles with epithelia cells and compared to those of uncoated ZnO.
- Autoren
- Moritz Susewind
- Anna-Maria Schilmann
- Julia Heim
- Andreas Henkel
- Thorben Link
- Karl Fischer
- Dennis Strand
- Ute Kolb
- Muhammad Nawaz Tahir
- Jürgen Brieger
- Wolfgang Tremel
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/32262254
- DOI
- 10.1039/c4tb02017k
- eISSN
- 2050-7518
- Ausgabe der Veröffentlichung
- 9
- Zeitschrift
- J Mater Chem B
- Sprache
- eng
- Country
- England
- Paginierung
- 1813 - 1822
- Datum der Veröffentlichung
- 2015
- Status
- Published
- Titel
- Silica-coated Au@ZnO Janus particles and their stability in epithelial cells.
- Sub types
- Journal Article
- Ausgabe der Zeitschrift
- 3
Data source: PubMed
- Autoren
- Andreas Henkel
- Wolfgang Tremel
- Urgen Brieger
- Muhammad Nawaz Tahir
- Ute Kolb
- Dennis Strand
- Karl Fischer
- Thorben Link
- Andreas Henkel
- Julia Heim
- Anna-Maria Schilmann
- Moritz Susewind
- DOI
- 10.1039/C4TB02017K
- Zeitschrift
- Journal of Materials Chemistry B
- Datum der Veröffentlichung
- 2015
- Herausgeber URL
- http://doi.org/10.1039/C4TB02017K
- Datum der Datenerfassung
- 2019
- Titel
- Silica-coated Au@ZnO Janus particles and their stability in epithelial cells
- Sub types
- article
Data source: Manual
- Beziehungen:
- Property of