Impact of Cross-Linking Procedure on Perioperative Quality of Life in Keratoconus Patients
- Publication type:
- Journal article
- Metadata:
-
- Abstract
- <jats:p>Background: To evaluate the effect of crosslinking (CXL) with riboflavin for keratoconus (KC) therapy on quality of life (QoL): comparison of keratoconus patients with and without treatment. Methods: Prospective monocentric study. We recruited patients with progressive KC and with stable disease. Patients with progressive disease received cross-linking treatment; patients with stable disease were monitored. We compared QoL in both groups over 6 months and detected the influence of cross-linking treatment on QoL. QoL was assessed by NEI-VFQ-25, EQ-5D 5L, and EQ-Visual analog scale (VAS). In the evaluation of the Nei VFQ, the subgroups LFVFS and LFSES were calculated. Results: We enrolled 31 eyes of 31 patients in the intervention group and 37 eyes of 37 patients in the control group. Medians with standard deviations (SD) were calculated. All QoL-tests showed equal scores at baseline in both groups. At V2, one day after the treatment, EQ-VAS (56.4), LFVFS (57.4), and EQ5D5L (0.59) were significantly reduced. At V3 (one week after treatment), all results returned to baseline level. LFSES was not affected by the treatment. It remained stable (V2 85.4, V3 84.3). Comparing the baseline scores with the follow-up scores at month 6, we found a significant increase in QoL in all tests in the intervention group. Otherwise, the quality of life in the control group did not change over time. Conclusions: Cross-linking led only to a short-term reduction in QoL. Although the treatment is painful for a few days, no effect on general quality of life LVSES has been demonstrated. QoL already returned to baseline after one week and the patients were not limited anymore.</jats:p>
- Autoren
- Susanne Marx-Gross
- Angelina Kroell
- Daniel Wollschlaeger
- Alexander K Schuster
- Jana C Riedl
- Joanna Wasielica-Poslednik
- Norbert Pfeiffer
- DOI
- 10.3390/jcm12113833
- eISSN
- 2077-0383
- Ausgabe der Veröffentlichung
- 11
- Zeitschrift
- Journal of Clinical Medicine
- Sprache
- en
- Online publication date
- 2023
- Paginierung
- 3833 - 3833
- Status
- Published online
- Herausgeber
- MDPI AG
- Herausgeber URL
- http://dx.doi.org/10.3390/jcm12113833
- Datum der Datenerfassung
- 2023
- Titel
- Impact of Cross-Linking Procedure on Perioperative Quality of Life in Keratoconus Patients
- Ausgabe der Zeitschrift
- 12
Data source: Crossref
- Other metadata sources:
-
- Author's licence
- CC-BY
- Autoren
- Susanne Marx-Gross
- Angelina Kroell
- Daniel Wollschlaeger
- Alexander K Schuster
- Jana C Riedl
- Joanna Wasielica-Poslednik
- Norbert Pfeiffer
- Hosting institution
- Universitätsbibliothek Mainz
- Sammlungen
- DFG-491381577-G
- Resource version
- Published version
- DOI
- 10.3390/jcm12113833
- File(s) embargoed
- false
- Open access
- true
- ISSN
- 2077-0383
- Ausgabe der Veröffentlichung
- 11
- Zeitschrift
- Journal of Clinical Medicine
- Schlüsselwörter
- 610 Medizin
- 610 Medical sciences
- Sprache
- eng
- Open access status
- Open Access
- Paginierung
- 3833
- Datum der Veröffentlichung
- 2023
- Public URL
- https://openscience.ub.uni-mainz.de/handle/20.500.12030/10054
- Herausgeber
- MDPI
- Datum der Datenerfassung
- 2024
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2024
- Zugang
- Public
- Titel
- Impact of cross-linking procedure on perioperative quality of life in keratoconus patients
- Ausgabe der Zeitschrift
- 12
Files
impact_of_crosslinking_proced-20240205155314422.pdf
Data source: OPENSCIENCE.UB