Preparation of substituted tetrahydropyran derivatives, using solid-phase synthesis, for use as medicines or diagnostic agents
Publication type:
Patent
Metadata:
Abstract
The invention relates to compounds of the formula [I; R-R4 independently = H, (un)substituted alkyl, (un)substituted alkenyl, (un)substituted alkynyl, alkoxy, (un)substituted carbamoyl, C(O)OR5; R5 = H, (un)substituted alkyl,(un)substituted alkenyl, (un)substituted alkynyl, alkoxy; R1,R2 or R2,R3 or R3,R4 together = (un)substituted alkyl; X = N, O], a method for producing them in a solid phase, and their use as medicines (no data). Thus, a differentially protected glycoside could be tethered to a solid support (Tentagel or aminomethyl-polystyrene), selectively deprotected, reacted to give derivatives, and de-tethered to give protected glycoside derivatives as α/β mixtures
Autoren
W Schmidt
S Henke
H Kunz
C Kallus
T Obatz
T Wunberg
Schlüsselwörter
saccharide derivative preparation solidphase
Notes
CAplus AN 1999:126910 (Patent)
Datum der Datenerfassung
2024
Awarded date
1999
Titel
Preparation of substituted tetrahydropyran derivatives, using solid-phase synthesis, for use as medicines or diagnostic agents