Electrochemical Synthesis of Sulfonamides in Single‐Pass Flow
- Publication type:
- Journal article
- Metadata:
-
- Abstract
- <jats:title>Abstract</jats:title><jats:p>An electrochemical multicomponent synthesis of sulfonamides at room temperature in single‐pass flow is presented. In contrast to batch‐type electrolysis, an undivided flow cell setup with a stainless‐steel cathode and either a boron‐doped diamond (BDD) anode or a glassy carbon anode can be employed. Simply by using SO<jats:sub>2</jats:sub> stock solutions, less atom‐economic sulfur dioxide surrogates can be avoided. Moreover, no additional supporting electrolytes are required due to the in‐situ generation of amidosulfinates, which also serve as intermediate for this transformation. This protocol allows sulfonamides to be synthesized directly from non‐prefunctionalized electron‐rich arenes with amines and SO<jats:sub>2</jats:sub>. In total, 10 examples are demonstrated with isolated yields up to 92 %. The robust scalability of this electrosynthesis with an easy downstream processing was also proven.</jats:p>
- Autoren
- Johannes Schneider
- Stephan P Blum
- Siegfried R Waldvogel
- DOI
- 10.1002/celc.202300456
- eISSN
- 2196-0216
- ISSN
- 2196-0216
- Ausgabe der Veröffentlichung
- 23
- Zeitschrift
- ChemElectroChem
- Sprache
- en
- Online publication date
- 2023
- Datum der Veröffentlichung
- 2023
- Status
- Published
- Herausgeber
- Wiley
- Herausgeber URL
- http://dx.doi.org/10.1002/celc.202300456
- Datum der Datenerfassung
- 2023
- Titel
- Electrochemical Synthesis of Sulfonamides in Single‐Pass Flow
- Ausgabe der Zeitschrift
- 10
Data source: Crossref
- Other metadata sources:
-
- Author's licence
- CC-BY
- Autoren
- Johannes Schneider
- Stephan P Blum
- Siegfried R Waldvogel
- Hosting institution
- Universitätsbibliothek Mainz
- Sammlungen
- DFG-491381577-G
- Resource version
- Published version
- DOI
- 10.1002/celc.202300456
- File(s) embargoed
- false
- Open access
- true
- ISSN
- 2196-0216
- Ausgabe der Veröffentlichung
- 23
- Zeitschrift
- ChemElectroChem
- Schlüsselwörter
- 540 Chemie
- 540 Chemistry and allied sciences
- Sprache
- eng
- Open access status
- Open Access
- Paginierung
- e202300456
- Datum der Veröffentlichung
- 2023
- Public URL
- https://openscience.ub.uni-mainz.de/handle/20.500.12030/9803
- Herausgeber
- Wiley-VCH
- Datum der Datenerfassung
- 2023
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2023
- Zugang
- Public
- Titel
- Electrochemical synthesis of sulfonamides in single-pass flow
- Ausgabe der Zeitschrift
- 10
Files
electrochemical_synthesis_of_-20231211112008463.pdf
Data source: OPENSCIENCE.UB