Electrochemical Synthesis of Isoxazoles and Isoxazolines via Anodic Oxidation of Oximes
- Publication type:
- Journal article
- Metadata:
-
- Abstract
- <jats:title>Abstract</jats:title><jats:p>Isoxazol(in)es are widely featured structural motifs in natural products, agrochemicals, and pharmaceuticals. The first intermolecular approach for a direct electrochemical synthesis from readily available aldoximes is reported. Isoxazoles and isoxazolines were obtained in yields up to 81 %. The synthesis is carried out in an undivided cell as the simplest electrochemical set‐up and requires only the use of electric current as traceless oxidizing agent. The application of inexpensive and widely available electrode materials in combination with recyclable supporting electrolytes and solvents paves the path for translation of the presented reaction onto preparative scale. This is underlined by successful scale‐up to multi‐gram runs.</jats:p>
- Autoren
- Silja Hofmann
- Johannes Winter
- Tobias Prenzel
- María de Jesús Gálvez‐Vázquez
- Siegfried R Waldvogel
- DOI
- 10.1002/celc.202300434
- eISSN
- 2196-0216
- ISSN
- 2196-0216
- Ausgabe der Veröffentlichung
- 22
- Zeitschrift
- ChemElectroChem
- Sprache
- en
- Online publication date
- 2023
- Datum der Veröffentlichung
- 2023
- Status
- Published
- Herausgeber
- Wiley
- Herausgeber URL
- http://dx.doi.org/10.1002/celc.202300434
- Datum der Datenerfassung
- 2023
- Titel
- Electrochemical Synthesis of Isoxazoles and Isoxazolines via Anodic Oxidation of Oximes
- Ausgabe der Zeitschrift
- 10
Data source: Crossref
- Other metadata sources:
-
- Author's licence
- CC-BY
- Autoren
- Silja Hofmann
- Johannes Winter
- Tobias Prenzel
- María de Jesús Gálvez-Vázquez
- Siegfried R Waldvogel
- Hosting institution
- Universitätsbibliothek Mainz
- Sammlungen
- DFG-491381577-G
- Resource version
- Published version
- DOI
- 10.1002/celc.202300434
- File(s) embargoed
- false
- Open access
- true
- ISSN
- 2196-0216
- Ausgabe der Veröffentlichung
- 22
- Zeitschrift
- ChemElectroChem
- Schlüsselwörter
- 540 Chemie
- 540 Chemistry and allied sciences
- Sprache
- eng
- Open access status
- Open Access
- Paginierung
- e202300434
- Datum der Veröffentlichung
- 2023
- Public URL
- https://openscience.ub.uni-mainz.de/handle/20.500.12030/9770
- Herausgeber
- Wiley-VCH
- Datum der Datenerfassung
- 2023
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2023
- Zugang
- Public
- Titel
- Electrochemical synthesis of isoxazoles and isoxazolines via anodic oxidation of oximes
- Ausgabe der Zeitschrift
- 10
Files
electrochemical_synthesis_of_-20231205123825416.pdf
Data source: OPENSCIENCE.UB