Resting state alpha frequency is associated with menstrual cycle phase, estradiol and use of oral contraceptives

Autoren

Christina P Brötzner
Wolfgang Klimesch
Michael Doppelmayr
Andrea Zauner
Hubert H Kerschbaum

DOI

10.1016/j.brainres.2014.06.034

ISSN

0006-8993

Zeitschrift

Brain Research

Sprache

en

Paginierung

36 - 44

Datum der Veröffentlichung

2014

Status

Published

Herausgeber

Elsevier BV

Herausgeber URL

http://dx.doi.org/10.1016/j.brainres.2014.06.034

Datum der Datenerfassung

2019

Titel

Resting state alpha frequency is associated with menstrual cycle phase, estradiol and use of oral contraceptives

Ausgabe der Zeitschrift

1577

Data source: Crossref

Abstract

Ongoing intrinsic brain activity in resting, but awake humans is dominated by alpha oscillations. In human, individual alpha frequency (IAF) is associated with cognitive performance. Noticeable, performance in cognitive and emotional tasks in women is associated with menstrual cycle phase and sex hormone levels, respectively. In the present study, we correlated frequency of alpha oscillation in resting women with menstrual cycle phase, sex hormone level, or use of oral contraceptives. Electroencephalogram (EEG) was recorded from 57 women (aged 24.07 ± 3.67 years) having a natural menstrual cycle as well as from 57 women (aged 22.37 ± 2.20 years) using oral contraceptives while they sat in an armchair with eyes closed. Alpha frequency was related to the menstrual cycle phase. Luteal women showed highest and late follicular women showed lowest IAF or center frequency. Furthermore, IAF as well as center frequency correlated negatively with endogenous estradiol level, but did not reveal an association with endogenous progesterone. Women using oral contraceptives showed an alpha frequency similar to women in the early follicular phase. We suggest that endogenous estradiol modulate resting alpha frequency.

Addresses

Department of Cell Biology, University of Salzburg, Salzburg, Austria; Department of Physiological Psychology, University of Salzburg, Salzburg, Austria.

Autoren

Christina P Brötzner
Wolfgang Klimesch
Michael Doppelmayr
Andrea Zauner
Hubert H Kerschbaum

DOI

10.1016/j.brainres.2014.06.034

eISSN

1872-6240

Externe Identifier

PubMed Identifier: 25010817
PubMed Central ID: PMC4152552

Funding acknowledgements

Doctoral College “Imaging the Mind” of the Austrian Science Fund: FWF-W1233
Austrian Science Fund FWF: W 1233

Open access

true

ISSN

0006-8993

Zeitschrift

Brain research

Schlüsselwörter

Brain
Humans
Estradiol
Progesterone
Contraceptives, Oral
Electroencephalography
Alpha Rhythm
Follicular Phase
Luteal Phase
Rest
Adolescent
Adult
Female
Young Adult

Sprache

eng

Medium

Print-Electronic

Online publication date

2014

Open access status

Open Access

Paginierung

36 - 44

Datum der Veröffentlichung

2014

Status

Published

Publisher licence

CC BY-NC-ND

Datum der Datenerfassung

2014

Titel

Resting state alpha frequency is associated with menstrual cycle phase, estradiol and use of oral contraceptives.

Sub types

Research Support, Non-U.S. Gov't
research-article
Journal Article

Ausgabe der Zeitschrift

1577

Data source: Europe PubMed Central

Abstract

Ongoing intrinsic brain activity in resting, but awake humans is dominated by alpha oscillations. In human, individual alpha frequency (IAF) is associated with cognitive performance. Noticeable, performance in cognitive and emotional tasks in women is associated with menstrual cycle phase and sex hormone levels, respectively. In the present study, we correlated frequency of alpha oscillation in resting women with menstrual cycle phase, sex hormone level, or use of oral contraceptives. Electroencephalogram (EEG) was recorded from 57 women (aged 24.07 ± 3.67 years) having a natural menstrual cycle as well as from 57 women (aged 22.37 ± 2.20 years) using oral contraceptives while they sat in an armchair with eyes closed. Alpha frequency was related to the menstrual cycle phase. Luteal women showed highest and late follicular women showed lowest IAF or center frequency. Furthermore, IAF as well as center frequency correlated negatively with endogenous estradiol level, but did not reveal an association with endogenous progesterone. Women using oral contraceptives showed an alpha frequency similar to women in the early follicular phase. We suggest that endogenous estradiol modulate resting alpha frequency.

Date of acceptance

2014

Autoren

Christina P Brötzner
Wolfgang Klimesch
Michael Doppelmayr
Andrea Zauner
Hubert H Kerschbaum

Autoren-URL

https://www.ncbi.nlm.nih.gov/pubmed/25010817

DOI

10.1016/j.brainres.2014.06.034

eISSN

1872-6240

Externe Identifier

PubMed Central ID: PMC4152552

Funding acknowledgements

Austrian Science Fund FWF: W 1233

Ausgabe der Veröffentlichung

100

Zeitschrift

Brain Res

Schlüsselwörter

Center frequency
Estradiol
Individual alpha frequency
Oral contraceptive
Adolescent
Adult
Alpha Rhythm
Brain
Contraceptives, Oral
Electroencephalography
Estradiol
Female
Follicular Phase
Humans
Luteal Phase
Progesterone
Rest
Young Adult

Sprache

eng

Country

Netherlands

Paginierung

36 - 44

PII

S0006-8993(14)00879-8

Datum der Veröffentlichung

2014

Status

Published

Datum, an dem der Datensatz öffentlich gemacht wurde

2015

Titel

Resting state alpha frequency is associated with menstrual cycle phase, estradiol and use of oral contraceptives.

Sub types

Journal Article
Research Support, Non-U.S. Gov't

Ausgabe der Zeitschrift

1577

Data source: PubMed

Resting state alpha frequency is associated with menstrual cycle phase, estradiol and use of oral contraceptives

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