Beyond the Transport Function of Import Receptors: What's All the FUS about?

Publication type:
Journal article
Metadata:
Autoren
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000430677400007&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.1016/j.cell.2018.04.002
eISSN
1097-4172
Externe Identifier
  • Clarivate Analytics Document Solution ID: GD7GB
  • PubMed Identifier: 29677508
ISSN
0092-8674
Ausgabe der Veröffentlichung
3
Zeitschrift
CELL
Paginierung
549 - 553
Datum der Veröffentlichung
2018
Status
Published
Titel
Beyond the Transport Function of Import Receptors: What's All the FUS about?
Sub types
  • Review
Ausgabe der Zeitschrift
173

Data source: Web of Science (Lite)

Other metadata sources:
Autoren
DOI
10.1016/j.cell.2018.04.002
ISSN
0092-8674
Ausgabe der Veröffentlichung
3
Zeitschrift
Cell
Sprache
en
Paginierung
549 - 553
Datum der Veröffentlichung
2018
Status
Published
Herausgeber
Elsevier BV
Herausgeber URL
http://dx.doi.org/10.1016/j.cell.2018.04.002
Datum der Datenerfassung
2020
Titel
Beyond the Transport Function of Import Receptors: What’s All the FUS about?
Ausgabe der Zeitschrift
173

Data source: Crossref

Abstract
Nuclear import receptors are central players in transporting protein cargoes into the nucleus. Moving beyond this role, four newly published articles describe a function in regulating supramolecular assemblies by fine-tuning the phase separating properties of RNA-binding proteins, which has implications for a variety of devastating neurodegenerative disorders.
Addresses
  • European Molecular Biology Laboratory, Meyerhofstrasse 1, 69117 Heidelberg, Germany.
Autoren
DOI
10.1016/j.cell.2018.04.002
eISSN
1097-4172
Externe Identifier
  • PubMed Identifier: 29677508
  • PubMed Central ID: PMC7611746
Funding acknowledgements
  • DFG: SFB1129
  • European Research Council: SMPFv2.0
  • European Research Council: 646451
Open access
false
ISSN
0092-8674
Ausgabe der Veröffentlichung
3
Zeitschrift
Cell
Schlüsselwörter
  • Cell Nucleus
  • Animals
  • Humans
  • Amyotrophic Lateral Sclerosis
  • Neurodegenerative Diseases
  • Karyopherins
  • RNA-Binding Proteins
  • RNA-Binding Protein FUS
  • DNA-Binding Proteins
  • Proteome
  • Receptors, Cytoplasmic and Nuclear
  • RNA
  • Active Transport, Cell Nucleus
  • Models, Biological
Sprache
eng
Medium
Print
Paginierung
549 - 553
Datum der Veröffentlichung
2018
Status
Published
Datum der Datenerfassung
2018
Titel
Beyond the Transport Function of Import Receptors: What's All the FUS about?
Sub types
  • Research Support, Non-U.S. Gov't
  • research-article
  • Review
  • Journal Article
Ausgabe der Zeitschrift
173

Files

http://www.cell.com/article/S0092867418304550/pdf https://europepmc.org/articles/PMC7611746?pdf=render

Data source: Europe PubMed Central

Abstract
Nuclear import receptors are central players in transporting protein cargoes into the nucleus. Moving beyond this role, four newly published articles describe a function in regulating supramolecular assemblies by fine-tuning the phase separating properties of RNA-binding proteins, which has implications for a variety of devastating neurodegenerative disorders.
Autoren
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/29677508
DOI
10.1016/j.cell.2018.04.002
eISSN
1097-4172
Externe Identifier
  • NIH Manuscript Submission ID: EMS134951
  • PubMed Central ID: PMC7611746
Funding acknowledgements
  • European Research Council: 646451
Ausgabe der Veröffentlichung
3
Zeitschrift
Cell
Schlüsselwörter
  • Active Transport, Cell Nucleus
  • Amyotrophic Lateral Sclerosis
  • Animals
  • Cell Nucleus
  • DNA-Binding Proteins
  • Humans
  • Karyopherins
  • Models, Biological
  • Neurodegenerative Diseases
  • Proteome
  • RNA
  • RNA-Binding Protein FUS
  • RNA-Binding Proteins
  • Receptors, Cytoplasmic and Nuclear
Sprache
eng
Country
United States
Paginierung
549 - 553
PII
S0092-8674(18)30455-0
Datum der Veröffentlichung
2018
Status
Published
Datum, an dem der Datensatz öffentlich gemacht wurde
2019
Titel
Beyond the Transport Function of Import Receptors: What's All the FUS about?
Sub types
  • Journal Article
  • Research Support, Non-U.S. Gov't
  • Review
Ausgabe der Zeitschrift
173

Data source: PubMed

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