Multiple Protein Sequence Alignment with MSAProbs
- Publication type:
- Chapter
- Metadata:
-
- Autoren
- Yongchao Liu
- Bertil Schmidt
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000328376500015&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1007/978-1-62703-646-7_14
- ISBN-13
- 978-1-62703-646-7
- Schlüsselwörter
- Multiple sequence alignment
- Progressive alignment
- Hidden Markov models
- Partition function
- Consistency-based scheme
- Paginierung
- 211 - 218
- Buchtitel
- MULTIPLE SEQUENCE ALIGNMENT METHODS
- Datum der Veröffentlichung
- 2014
- Status
- Published
- Titel
- Multiple Protein Sequence Alignment with MSAProbs
- Ausgabe der Zeitschrift
- 1079
Data source: Web of Science (Lite)
- Other metadata sources:
-
- Autoren
- Yongchao Liu
- Bertil Schmidt
- DOI
- 10.1007/978-1-62703-646-7_14
- ISBN-13
- 9781627036450
- Online publication date
- 2013
- Paginierung
- 211 - 218
- Buchtitel
- Methods in Molecular Biology
- Datum der Veröffentlichung
- 2014
- Status
- Published
- Herausgeber
- Humana Press
- Herausgeber URL
- http://dx.doi.org/10.1007/978-1-62703-646-7_14
- Datum der Datenerfassung
- 2019
- Titel
- Multiple Protein Sequence Alignment with MSAProbs
Data source: Crossref
- Abstract
- Multiple sequence alignment (MSA) generally constitutes the foundation of many bioinformatics studies involving functional, structural, and evolutionary relationship analysis between sequences. As a result of the exponential computational complexity of the exact approach to producing optimal multiple alignments, the majority of state-of-the-art MSA algorithms are designed based on the progressive alignment heuristic. In this chapter, we outline MSAProbs, a parallelized MSA algorithm for protein sequences based on progressive alignment. To achieve high alignment accuracy, this algorithm employs a hybrid combination of a pair hidden Markov model and a partition function to calculate posterior probabilities. Furthermore, we provide some practical advice on the usage of the algorithm.
- Addresses
- Institut für Informatik, Johannes Gutenberg Universitat Mainz, Mainz, Germany.
- Autoren
- Yongchao Liu
- Bertil Schmidt
- DOI
- 10.1007/978-1-62703-646-7_14
- Open access
- false
- Schlüsselwörter
- Proteins
- Markov Chains
- Sequence Alignment
- Computational Biology
- Algorithms
- Software
- Medium
- Paginierung
- 211 - 218
- Datum der Veröffentlichung
- 2014
- Status
- Published
- Datum der Datenerfassung
- 2013
- Titel
- Multiple protein sequence alignment with MSAProbs.
- Ausgabe der Zeitschrift
- 1079
Data source: Europe PubMed Central
- Abstract
- Multiple sequence alignment (MSA) generally constitutes the foundation of many bioinformatics studies involving functional, structural, and evolutionary relationship analysis between sequences. As a result of the exponential computational complexity of the exact approach to producing optimal multiple alignments, the majority of state-of-the-art MSA algorithms are designed based on the progressive alignment heuristic. In this chapter, we outline MSAProbs, a parallelized MSA algorithm for protein sequences based on progressive alignment. To achieve high alignment accuracy, this algorithm employs a hybrid combination of a pair hidden Markov model and a partition function to calculate posterior probabilities. Furthermore, we provide some practical advice on the usage of the algorithm.
- Autoren
- Yongchao Liu
- Bertil Schmidt
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/24170405
- DOI
- 10.1007/978-1-62703-646-7_14
- Schlüsselwörter
- Algorithms
- Computational Biology
- Markov Chains
- Proteins
- Sequence Alignment
- Software
- Paginierung
- 211 - 218
- Datum der Veröffentlichung
- 2014
- Status
- Published
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2014
- Titel
- Multiple protein sequence alignment with MSAProbs.
- Ausgabe der Zeitschrift
- 1079
Data source: PubMed
- Beziehungen:
- Property of