Childhood glaucoma registry in Germany: initial database, clinical care and research (pilot study)
- Publication type:
- Journal article
- Metadata:
-
- Abstract
- <jats:title>Abstract</jats:title><jats:sec> <jats:title>Objective</jats:title> <jats:p>The aim of this prospective pilot study is to establish an initial database to register patients diagnosed with different types of childhood glaucoma and the set-up of a national registry for childhood glaucoma (ReCG) in Germany. 28 children with different types of diagnosed childhood glaucoma, who were admitted and treated at the Childhood Glaucoma Center of the University Medical Center Mainz, Germany were included. Main outcome measures were the type of childhood glaucoma, mean intraocular pressure (IOP) and genetic data of the patients.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>The documents and questionnaires for each individual included: informed consent form of the parents, medical history form of the child, patient’s gestational history questionnaire and general anesthesia examination form. Primary congenital and secondary childhood glaucoma were revealed in 11 (39%) and 17 (61%) patients, respectively. The mean IOP measured with Perkins tonometer in all patients under general anesthesia at the time of inclusion was 17.5 ± 11.8 mmHg in the right and 17 ± 8.9 mmHg in the left eyes. In 33% of children with glaucoma mutations in the CYP1B1, FOXC1, LTBP2 and TEK genes were found. The development of specific questionnaires for childhood glaucoma provides detailed baseline data to establish a ReCG in Germany for the first time.</jats:p> </jats:sec>
- Autoren
- Fidan A Aghayeva
- Alexander K Schuster
- Heidi Diel
- Panagiotis Chronopoulos
- Felix M Wagner
- Franz Grehn
- Nina Pirlich
- Susann Schweiger
- Norbert Pfeiffer
- Esther M Hoffmann
- DOI
- 10.1186/s13104-022-05921-8
- eISSN
- 1756-0500
- Ausgabe der Veröffentlichung
- 1
- Zeitschrift
- BMC Research Notes
- Sprache
- en
- Artikelnummer
- 32
- Online publication date
- 2022
- Datum der Veröffentlichung
- 2022
- Status
- Published
- Herausgeber
- Springer Science and Business Media LLC
- Herausgeber URL
- http://dx.doi.org/10.1186/s13104-022-05921-8
- Datum der Datenerfassung
- 2022
- Titel
- Childhood glaucoma registry in Germany: initial database, clinical care and research (pilot study)
- Ausgabe der Zeitschrift
- 15
Data source: Crossref
- Other metadata sources:
-
- Author's licence
- CC-BY
- Autoren
- Fidan A Aghayeva
- Alexander K Schuster
- Heidi Diel
- Panagiotis Chronopoulos
- Felix M Wagner
- Franz Grehn
- Nina Pirlich
- Susann Schweiger
- Norbert Pfeiffer
- Esther M Hoffmann
- Hosting institution
- Universitätsbibliothek Mainz
- Sammlungen
- DFG-491381577-G
- Resource version
- Published version
- DOI
- 10.1186/s13104-022-05921-8
- Funding acknowledgements
- Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) - Projektnummer 491381577
- File(s) embargoed
- false
- Open access
- true
- ISSN
- 1756-0500
- Zeitschrift
- BMC Research Notes
- Schlüsselwörter
- 610 Medizin
- 610 Medical sciences
- Sprache
- eng
- Open access status
- Open Access
- Paginierung
- 32
- Datum der Veröffentlichung
- 2022
- Public URL
- https://openscience.ub.uni-mainz.de/handle/20.500.12030/8770
- Herausgeber
- BMC
- Datum der Datenerfassung
- 2023
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2023
- Zugang
- Public
- Titel
- Childhood glaucoma registry in Germany : initial database, clinical care and research (pilot study)
- Ausgabe der Zeitschrift
- 15
Files
childhood_glaucoma_registry_i-20230202104252672.pdf
Data source: OPENSCIENCE.UB