Rapid Precipitation of Ionomers for Stabilization of Polymeric Colloids

Autoren

Douglas M Scott
Arash Nikoubashman
Richard A Register
Rodney D Priestley
Robert K Prud’homme

DOI

10.1021/acs.langmuir.2c02850

eISSN

1520-5827

ISSN

0743-7463

Ausgabe der Veröffentlichung

1

Zeitschrift

Langmuir

Sprache

en

Online publication date

2022

Paginierung

570 - 578

Datum der Veröffentlichung

2023

Status

Published

Herausgeber

American Chemical Society (ACS)

Herausgeber URL

http://dx.doi.org/10.1021/acs.langmuir.2c02850

Datum der Datenerfassung

2023

Titel

Rapid Precipitation of Ionomers for Stabilization of Polymeric Colloids

Ausgabe der Zeitschrift

39

Data source: Crossref

Abstract

Polymeric colloids have shown potential as "building blocks" in applications ranging from formulations of Pickering emulsions and drug delivery systems to advanced materials, including colloidal crystals and composites. However, for applications requiring tunable properties of charged colloids, obstacles in fabrication can arise through limitations in process scalability and chemical versatility. In this work, the capabilities of flash nanoprecipitation (FNP), a scalable nanoparticle (NP) fabrication technology, are expanded to produce charged polystyrene colloids using sulfonated polystyrene ionomers as a new class of NP stabilizers. Through experimental exploration of formulation parameters, increases in the ionomer content are shown to reduce the particle size, mitigating a significant trade-off between the final particle size and inlet concentration; thus, expanding the processable material throughput of FNP. Further, the degree of sulfonation is found to impact stabilization with optimal performance achieved by selecting ionomers with intermediate (2.45-5.2 mol %) sulfonation. Simulations of single ionomer chains and their arrangement in multicomponent NPs provide molecular insights into the assembly and structure of NPs wherein the partitioning of ionomers to the particle surface depends on the polymer molecular weight and degree of sulfonation. By combining the insights from simulations with diffusion-limited growth kinetics and parametric fits to experimental data, a simple design formulation relation is proposed and validated. This work highlights the potential of ionomer-based stabilizers for controllably producing charged NP dispersions in a scalable manner.

Addresses

Department of Chemical and Biological Engineering, Princeton University, Princeton, New Jersey08544, United States.

Autoren

Douglas M Scott
Arash Nikoubashman
Richard A Register
Rodney D Priestley
Robert K Prud'homme

DOI

10.1021/acs.langmuir.2c02850

eISSN

1520-5827

Externe Identifier

PubMed Identifier: 36577027

Funding acknowledgements

Division of Materials Research: DMR-2011750
Deutsche Forschungsgemeinschaft: 233630050
Deutsche Forschungsgemeinschaft: 274340645
Deutsche Forschungsgemeinschaft: 405552959
Deutsche Forschungsgemeinschaft: 445740352
Deutsche Forschungsgemeinschaft: 470113688

Open access

false

ISSN

0743-7463

Ausgabe der Veröffentlichung

1

Zeitschrift

Langmuir : the ACS journal of surfaces and colloids

Sprache

eng

Medium

Print-Electronic

Online publication date

2022

Paginierung

570 - 578

Datum der Veröffentlichung

2023

Status

Published

Datum der Datenerfassung

2022

Titel

Rapid Precipitation of Ionomers for Stabilization of Polymeric Colloids.

Sub types

Journal Article

Ausgabe der Zeitschrift

39

Data source: Europe PubMed Central

Abstract

Polymeric colloids have shown potential as "building blocks" in applications ranging from formulations of Pickering emulsions and drug delivery systems to advanced materials, including colloidal crystals and composites. However, for applications requiring tunable properties of charged colloids, obstacles in fabrication can arise through limitations in process scalability and chemical versatility. In this work, the capabilities of flash nanoprecipitation (FNP), a scalable nanoparticle (NP) fabrication technology, are expanded to produce charged polystyrene colloids using sulfonated polystyrene ionomers as a new class of NP stabilizers. Through experimental exploration of formulation parameters, increases in the ionomer content are shown to reduce the particle size, mitigating a significant trade-off between the final particle size and inlet concentration; thus, expanding the processable material throughput of FNP. Further, the degree of sulfonation is found to impact stabilization with optimal performance achieved by selecting ionomers with intermediate (2.45-5.2 mol %) sulfonation. Simulations of single ionomer chains and their arrangement in multicomponent NPs provide molecular insights into the assembly and structure of NPs wherein the partitioning of ionomers to the particle surface depends on the polymer molecular weight and degree of sulfonation. By combining the insights from simulations with diffusion-limited growth kinetics and parametric fits to experimental data, a simple design formulation relation is proposed and validated. This work highlights the potential of ionomer-based stabilizers for controllably producing charged NP dispersions in a scalable manner.

Autoren

Douglas M Scott
Arash Nikoubashman
Richard A Register
Rodney D Priestley
Robert K Prud'homme

Autoren-URL

https://www.ncbi.nlm.nih.gov/pubmed/36577027

DOI

10.1021/acs.langmuir.2c02850

eISSN

1520-5827

Ausgabe der Veröffentlichung

1

Zeitschrift

Langmuir

Sprache

eng

Country

United States

Paginierung

570 - 578

Datum der Veröffentlichung

2023

Status

Published

Datum, an dem der Datensatz öffentlich gemacht wurde

2023

Titel

Rapid Precipitation of Ionomers for Stabilization of Polymeric Colloids.

Sub types

Journal Article

Ausgabe der Zeitschrift

39

Data source: PubMed

Rapid Precipitation of Ionomers for Stabilization of Polymeric Colloids

Tools