Electrochemical Installation of CFH2−, CF2H−, CF3−, and Perfluoroalkyl Groups into Small Organic Molecules

Publication type:
Journal article
Metadata:
Abstract
<jats:title>Abstract</jats:title><jats:p>Electrosynthesis can be considered a powerful and sustainable methodology for the synthesis of small organic molecules. Due to its intrinsic ability to generate highly reactive species under mild conditions by anodic oxidation or cathodic reduction, electrosynthesis is particularly interesting for otherwise challenging transformations. One such challenge is the installation of fluorinated alkyl groups, which has gained significant attention in medicinal chemistry and material science due to their unique physicochemical features. Unsurprisingly, several electrochemical fluoroalkylation methods have been established. In this review, we survey recent developments and established methods in the field of electrochemical mono‐, di‐, and trifluoromethylation, and perfluoroalkylation of small organic molecules.</jats:p>
Autoren
  • Camila M Kisukuri
  • Vitor A Fernandes
  • José AC Delgado
  • Andreas P Häring
  • Márcio W Paixão
  • Siegfried R Waldvogel
DOI
10.1002/tcr.202100065
eISSN
1528-0691
ISSN
1527-8999
Ausgabe der Veröffentlichung
9
Zeitschrift
The Chemical Record
Sprache
en
Online publication date
2021
Paginierung
2502 - 2525
Datum der Veröffentlichung
2021
Status
Published
Herausgeber
Wiley
Herausgeber URL
http://dx.doi.org/10.1002/tcr.202100065
Datum der Datenerfassung
2023
Titel
Electrochemical Installation of CFH<sub>2</sub>−, CF<sub>2</sub>H−, CF<sub>3</sub>−, and Perfluoroalkyl Groups into Small Organic Molecules
Ausgabe der Zeitschrift
21

Data source: Crossref

Other metadata sources:
Author's licence
CC-BY-NC-ND
Autoren
  • Camila M Kisukuri
  • Vitor A Fernandes
  • José AC Delgado
  • Andreas P Häring
  • Márcio W Paixão
  • Siegfried R Waldvogel
Hosting institution
Universitätsbibliothek Mainz
Sammlungen
  • JGU-Publikationen
Resource version
Published version
DOI
10.1002/tcr.202100065
File(s) embargoed
false
Open access
true
ISSN
1528-0691
Ausgabe der Veröffentlichung
9
Zeitschrift
The chemical record
Schlüsselwörter
  • 540 Chemie
  • 540 Chemistry and allied sciences
Sprache
eng
Open access status
Open Access
Paginierung
2502 - 2525
Datum der Veröffentlichung
2021
Public URL
https://openscience.ub.uni-mainz.de/handle/20.500.12030/8093
Herausgeber
Wiley-VCH
Datum der Datenerfassung
2022
Datum, an dem der Datensatz öffentlich gemacht wurde
2022
Zugang
Public
Titel
Electrochemical installation of CFH2−, CF2H−, CF3−, and perfluoroalkyl groups into small organic molecules
Ausgabe der Zeitschrift
21

Files

electrochemical_installation_-20221017144559712.pdf

Data source: OPENSCIENCE.UB

Tools