Right atrium size in the general population
- Publication type:
- Journal article
- Metadata:
-
- Abstract
- <jats:title>Abstract</jats:title><jats:p>Echocardiography is the most common routine cardiac imaging method. Nevertheless, only few data about sex-specific reference limits for right atrium (RA) dimensions are available. Transthoracic echocardiographic RA measurements were studied in 9511 participants of the Gutenberg-Health-Study. A reference sample of 1942 cardiovascular healthy subjects without chronic obstructive pulmonary disease was defined. We assessed RA dimensions and sex-specific reference limits were defined using the 95th percentile of the reference sample. Results showed sex-specific differences with larger RA dimensions in men that were attenuated by standardization for body-height. RA-volume was 20.2 ml/m in women (5th–95th: 12.7–30.4 ml/m) and 26.1 ml/m in men (5th–95th: 16.0–40.5 ml/m). Multivariable regressions identified body-mass-index (BMI), coronary artery disease (CAD), chronic heart failure (CHF) and atrial fibrillation (AF) as independent key correlates of RA-volume in both sexes. All-cause mortality after median follow-up-period of 10.7 (9.81/11.6) years was higher in individuals who had RA volume/height outside the 95% reference limit (HR 1.70 [95%CI 1.29–2.23], <jats:italic>P</jats:italic> = 0.00014)). Based on a large community-based sample, we present sex-specific reference-values for RA dimensions normalized for height. RA-volume varies with BMI, CHF, CAD and AF in both sexes. Individuals with RA-volume outside the reference limit had a 1.7-fold higher mortality than those within reference limits. </jats:p>
- Autoren
- Karsten Keller
- Christoph Sinning
- Andreas Schulz
- Claus Jünger
- Volker H Schmitt
- Omar Hahad
- Tanja Zeller
- Manfred Beutel
- Norbert Pfeiffer
- Konstantin Strauch
- Stefan Blankenberg
- Karl J Lackner
- Jürgen H Prochaska
- Eberhard Schulz
- Thomas Münzel
- Philipp S Wild
- DOI
- 10.1038/s41598-021-01968-y
- eISSN
- 2045-2322
- Ausgabe der Veröffentlichung
- 1
- Zeitschrift
- Scientific Reports
- Sprache
- en
- Artikelnummer
- 22523
- Online publication date
- 2021
- Status
- Published online
- Herausgeber
- Springer Science and Business Media LLC
- Herausgeber URL
- http://dx.doi.org/10.1038/s41598-021-01968-y
- Datum der Datenerfassung
- 2022
- Titel
- Right atrium size in the general population
- Ausgabe der Zeitschrift
- 11
Data source: Crossref
- Other metadata sources:
-
- Author's licence
- CC-BY
- Autoren
- Karsten Keller
- Christoph Sinning
- Andreas Schulz
- Claus Jünger
- Volker H Schmitt
- Omar Hahad
- Tanja Zeller
- Manfred Beutel
- Norbert Pfeiffer
- Konstantin Strauch
- Stefan Blankenberg
- Karl J Lackner
- Jürgen H Prochaska
- Eberhard Schulz
- Thomas Münzel
- Philipp S Wild
- Hosting institution
- Universitätsbibliothek Mainz
- Sammlungen
- JGU-Publikationen
- Resource version
- Published version
- DOI
- 10.1038/s41598-021-01968-y
- File(s) embargoed
- false
- Open access
- true
- ISSN
- 2045-2322
- Zeitschrift
- Scientific reports
- Schlüsselwörter
- 610 Medizin
- 610 Medical sciences
- Sprache
- eng
- Open access status
- Open Access
- Paginierung
- 22523
- Datum der Veröffentlichung
- 2021
- Public URL
- https://openscience.ub.uni-mainz.de/handle/20.500.12030/7535
- Herausgeber
- Macmillan Publishers Limited, part of Springer Nature
- Datum der Datenerfassung
- 2022
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2022
- Zugang
- Public
- Titel
- Right atrium size in the general population
- Ausgabe der Zeitschrift
- 11
Files
right_atrium_size_in_the_gene-20220805120923187.pdf
Data source: OPENSCIENCE.UB