Integrating Nanosensors into Macroporous Hydrogels for Implantation
- Publication type:
- Journal article
- Metadata:
-
- Autoren
- Katja Buder
- Katharina Kaefer
- Bastian Flietel
- Huseyin Uzun
- Thies Schroeder
- Carsten Sonnichsen
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000781540500007&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1021/acsabm.1c01290
- Externe Identifier
- Clarivate Analytics Document Solution ID: 0L5VI
- PubMed Identifier: 35138094
- ISSN
- 2576-6422
- Ausgabe der Veröffentlichung
- 2
- Zeitschrift
- ACS APPLIED BIO MATERIALS
- Schlüsselwörter
- plasmon sensing
- macroporous scaffold
- polymer implant
- gold nanoparticles
- implantable sensors
- in vivo sensing
- Paginierung
- 465 - 470
- Datum der Veröffentlichung
- 2022
- Status
- Published
- Titel
- Integrating Nanosensors into Macroporous Hydrogels for Implantation
- Sub types
- Article
- Ausgabe der Zeitschrift
- 5
Data source: Web of Science (Lite)
- Other metadata sources:
-
- Autoren
- Katja Buder
- Katharina Kaefer
- Bastian Flietel
- Hüseyin Uzun
- Thies Schroeder
- Carsten Sönnichsen
- DOI
- 10.1021/acsabm.1c01290
- eISSN
- 2576-6422
- ISSN
- 2576-6422
- Ausgabe der Veröffentlichung
- 2
- Zeitschrift
- ACS Applied Bio Materials
- Sprache
- en
- Online publication date
- 2022
- Paginierung
- 465 - 470
- Datum der Veröffentlichung
- 2022
- Status
- Published
- Herausgeber
- American Chemical Society (ACS)
- Herausgeber URL
- http://dx.doi.org/10.1021/acsabm.1c01290
- Datum der Datenerfassung
- 2023
- Titel
- Integrating Nanosensors into Macroporous Hydrogels for Implantation
- Ausgabe der Zeitschrift
- 5
Data source: Crossref
- Abstract
- Macroporous hydrogels are an attractive platform for implantable sensors because the network of interconnected macropores facilitates tissue integration. Embedded sensing elements, in our case, plasmonic gold nanoparticles, can transduce the presence, absence, and concentration of biochemical markers to the outside. We present here how to integrate such nanosensors into a macroporous hydrogel while preserving the nanosensor functionality in order to produce implantable sensors. We demonstrate that out of four different polymers, the poly(2-hydroxyethyl methacrylate-poly(ethylene glycole)diacrylate copolymer (pHEMA-PEGDA) results in a working sensor. Our approach of incorporating nanosized sensor elements into a hydrogel matrix generally identifies suitable polymers for implantable sensor systems.
- Addresses
- Department of Chemistry, Johannes Gutenberg-University of Mainz, Duesbergweg 10-14, Mainz 55128, Germany.
- Autoren
- Katja Buder
- Katharina Kaefer
- Bastian Flietel
- Hüseyin Uzun
- Thies Schroeder
- Carsten Sönnichsen
- DOI
- 10.1021/acsabm.1c01290
- eISSN
- 2576-6422
- Externe Identifier
- PubMed Identifier: 35138094
- Funding acknowledgements
- Johannes Gutenberg-Universit?t Mainz:
- Stiftung Rheinland-Pfalz f?r Innovation: 1176
- Open access
- false
- ISSN
- 2576-6422
- Ausgabe der Veröffentlichung
- 2
- Zeitschrift
- ACS applied bio materials
- Schlüsselwörter
- Gold
- Polyhydroxyethyl Methacrylate
- Hydrogels
- Metal Nanoparticles
- Sprache
- eng
- Medium
- Print-Electronic
- Online publication date
- 2022
- Paginierung
- 465 - 470
- Datum der Veröffentlichung
- 2022
- Status
- Published
- Datum der Datenerfassung
- 2022
- Titel
- Integrating Nanosensors into Macroporous Hydrogels for Implantation.
- Sub types
- Research Support, Non-U.S. Gov't
- Journal Article
- Ausgabe der Zeitschrift
- 5
Data source: Europe PubMed Central
- Abstract
- Macroporous hydrogels are an attractive platform for implantable sensors because the network of interconnected macropores facilitates tissue integration. Embedded sensing elements, in our case, plasmonic gold nanoparticles, can transduce the presence, absence, and concentration of biochemical markers to the outside. We present here how to integrate such nanosensors into a macroporous hydrogel while preserving the nanosensor functionality in order to produce implantable sensors. We demonstrate that out of four different polymers, the poly(2-hydroxyethyl methacrylate-poly(ethylene glycole)diacrylate copolymer (pHEMA-PEGDA) results in a working sensor. Our approach of incorporating nanosized sensor elements into a hydrogel matrix generally identifies suitable polymers for implantable sensor systems.
- Autoren
- Katja Buder
- Katharina Kaefer
- Bastian Flietel
- Hüseyin Uzun
- Thies Schroeder
- Carsten Sönnichsen
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/35138094
- DOI
- 10.1021/acsabm.1c01290
- eISSN
- 2576-6422
- Ausgabe der Veröffentlichung
- 2
- Zeitschrift
- ACS Appl Bio Mater
- Schlüsselwörter
- gold nanoparticles
- implantable sensors
- in vivo sensing
- macroporous scaffold
- plasmon sensing
- polymer implant
- Gold
- Hydrogels
- Metal Nanoparticles
- Polyhydroxyethyl Methacrylate
- Sprache
- eng
- Country
- United States
- Paginierung
- 465 - 470
- Datum der Veröffentlichung
- 2022
- Status
- Published
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2022
- Titel
- Integrating Nanosensors into Macroporous Hydrogels for Implantation.
- Sub types
- Journal Article
- Research Support, Non-U.S. Gov't
- Ausgabe der Zeitschrift
- 5
Data source: PubMed
- Beziehungen:
- Property of