Enhanced extraction of isoflavonoids from Radix Astragali by incubation pretreatment combined with negative pressure cavitation and its antioxidant activity

Publication type:
Journal article
Metadata:
Autoren
  • Bao-Shan Zhao
  • Yu-Jie Fu
  • Wei Wang
  • Yuan-Gang Zu
  • Cheng-Bo Gu
  • Meng Luo
  • Thomas Efferth
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000297232000023&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.1016/j.ifset.2011.05.003
eISSN
1878-5522
Externe Identifier
  • Clarivate Analytics Document Solution ID: 850XD
ISSN
1466-8564
Ausgabe der Veröffentlichung
4
Zeitschrift
INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES
Schlüsselwörter
  • Incubation pretreatment
  • Endogenous enzyme
  • Negative-pressure cavitation extraction
  • Calycosin
  • Formononetin
  • Radix Astragali
Paginierung
577 - 585
Datum der Veröffentlichung
2011
Status
Published
Titel
Enhanced extraction of isoflavonoids from Radix Astragali by incubation pretreatment combined with negative pressure cavitation and its antioxidant activity
Sub types
  • Article
Ausgabe der Zeitschrift
12

Data source: Web of Science (Lite)

Other metadata sources:
Autoren
  • Bao-Shan Zhao
  • Yu-Jie Fu
  • Wei Wang
  • Yuan-Gang Zu
  • Cheng-Bo Gu
  • Meng Luo
  • Thomas Efferth
DOI
10.1016/j.ifset.2011.05.003
ISSN
1466-8564
Ausgabe der Veröffentlichung
4
Zeitschrift
Innovative Food Science & Emerging Technologies
Sprache
en
Paginierung
577 - 585
Datum der Veröffentlichung
2011
Status
Published
Herausgeber
Elsevier BV
Herausgeber URL
http://dx.doi.org/10.1016/j.ifset.2011.05.003
Datum der Datenerfassung
2022
Titel
Enhanced extraction of isoflavonoids from Radix Astragali by incubation pretreatment combined with negative pressure cavitation and its antioxidant activity
Ausgabe der Zeitschrift
12

Data source: Crossref

Abstract
Incubation pretreatment with the function of endogenous enzyme combined with negative-pressure cavitation extraction (IP-NPCE) was established to extract calycosin and formononetin from Radix Astragali. Significant factors involved in the process were selected using Plackett–Burman factorial design (PBD) and then were optimized by central composite design (CCD). The optimum experimental conditions were incubation at 35°C, 60min, pH 4.0 and extraction at negative pressure −0.080MPa, ethanol concentration 60%, 60 mesh, 30min, solid-to-liquid ratio 1:25 and two cycles. Under the optimal conditions, the extraction yields of calycosin and formononetin were 0.650±0.015 and 0.307±0.013mg/g (n=3), which were 94.67% and 56.63% higher than those without incubation pretreatment, respectively. Furthermore, the antioxidant activities of extracts of IP-NPCE were 1.845mg/mL (IC₅₀) and 0.703mmol Fe(II)/g according to the DPPH and FRAP assays, respectively. This novel extraction technique gave higher yields and better antioxidant activities against other extraction methods. INDUSTRIAL RELEVANCE: According to our present study, the decomposition of the material itself endogenous enzyme combined with NPCE for the target components was first proposed. This novel extraction technique also processes the advantages of mild operating conditions, high material throughput and low equipment expenditure. The results of the present study may provide valuable data for process design and pilot-scale as well as industrial scale-up applications.
Autoren
  • Bao-Shan Zhao
  • Yu-Jie Fu
  • Wei Wang
  • Yuan-Gang Zu
  • Cheng-Bo Gu
  • Meng Luo
  • Thomas Efferth
  • Thomas Efferth
DOI
10.1016/j.ifset.2011.05.003
Open access
false
ISSN
1466-8564
Ausgabe der Veröffentlichung
4
Zeitschrift
Innovative Food Science and Emerging Technologies.
Sprache
eng
Medium
Undetermined
Paginierung
577 - 585
Datum der Veröffentlichung
2011
Status
Published
Datum der Datenerfassung
2014
Titel
Enhanced extraction of isoflavonoids from Radix Astragali by incubation pretreatment combined with negative pressure cavitation and its antioxidant activity
Sub types
  • Journal Article
Ausgabe der Zeitschrift
12

Data source: Europe PubMed Central

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