Sarcoehrenbergilides D-F: cytotoxic cembrene diterpenoids from the soft coral Sarcophyton ehrenbergi

Publication type:
Journal article
Metadata:
Autoren
  • Mohamed-Elamir F Hegazy
  • Tarik A Mohamed
  • Abdelsamed I Elshamy
  • Ahmed R Hamed
  • Mahmoud AA Ibrahim
  • Shinji Ohta
  • Akemi Umeyama
  • Paul W Pare
  • Thomas Efferth
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000487054800006&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.1039/c9ra04158c
eISSN
2046-2069
Externe Identifier
  • Clarivate Analytics Document Solution ID: IZ4LH
  • PubMed Identifier: 35529183
Ausgabe der Veröffentlichung
47
Zeitschrift
RSC ADVANCES
Paginierung
27183 - 27189
Datum der Veröffentlichung
2019
Status
Published
Titel
Sarcoehrenbergilides D-F: cytotoxic cembrene diterpenoids from the soft coral <i>Sarcophyton ehrenbergi</i>
Sub types
  • Article
Ausgabe der Zeitschrift
9

Data source: Web of Science (Lite)

Other metadata sources:
Abstract
<p>A solvent extract of the soft coral <italic>Sarcophyton ehrenbergi</italic> afforded cembrene diterpenoids, sarcoehrenbergilid D–F (<bold>1–3</bold>).</p>
Autoren
  • Mohamed-Elamir F Hegazy
  • Tarik A Mohamed
  • Abdelsamed I Elshamy
  • Ahmed R Hamed
  • Mahmoud AA Ibrahim
  • Shinji Ohta
  • Akemi Umeyama
  • Paul W Paré
  • Thomas Efferth
DOI
10.1039/c9ra04158c
eISSN
2046-2069
Ausgabe der Veröffentlichung
47
Zeitschrift
RSC Advances
Sprache
en
Online publication date
2019
Paginierung
27183 - 27189
Status
Published online
Herausgeber
Royal Society of Chemistry (RSC)
Herausgeber URL
http://dx.doi.org/10.1039/c9ra04158c
Datum der Datenerfassung
2024
Titel
Sarcoehrenbergilides D–F: cytotoxic cembrene diterpenoids from the soft coral <i>Sarcophyton ehrenbergi</i>
Ausgabe der Zeitschrift
9

Data source: Crossref

Abstract
A solvent extract of the soft coral <i>Sarcophyton ehrenbergi</i> afforded cembrene diterpenoids, sarcoehrenbergilid D-F (1-3). Chemical structures were established by modern spectroscopic techniques with absolute stereochemistries determined by circular dichroism (CD) and time-dependent density functional theory electronic CD calculations (TDDFT-ECD). Cytotoxicity activities for 1-3 were evaluated against three human cancer cell lines: lung (A549), colon (Caco-2) and liver (HepG2).
Addresses
  • Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemistry, Johannes Gutenberg University Staudinger Weg 5 55128 Mainz Germany.
Autoren
  • Mohamed-Elamir F Hegazy
  • Tarik A Mohamed
  • Abdelsamed I Elshamy
  • Ahmed R Hamed
  • Mahmoud AA Ibrahim
  • Shinji Ohta
  • Akemi Umeyama
  • Paul W Paré
  • Thomas Efferth
DOI
10.1039/c9ra04158c
eISSN
2046-2069
Externe Identifier
  • PubMed Identifier: 35529183
  • PubMed Central ID: PMC9070672
Funding acknowledgements
  • Alexander von Humboldt-Stiftung:
  • National Research Centre:
  • Science and Technology Development Fund: 5480
  • Science and Technology Development Fund: 7972
  • Takeda Science Foundation:
  • Welch Foundation: D1478
Open access
true
ISSN
2046-2069
Ausgabe der Veröffentlichung
47
Zeitschrift
RSC advances
Sprache
eng
Medium
Electronic-eCollection
Online publication date
2019
Open access status
Open Access
Paginierung
27183 - 27189
Datum der Veröffentlichung
2019
Status
Published
Publisher licence
CC BY
Datum der Datenerfassung
2022
Titel
Sarcoehrenbergilides D-F: cytotoxic cembrene diterpenoids from the soft coral <i>Sarcophyton ehrenbergi</i>.
Sub types
  • research-article
  • Journal Article
Ausgabe der Zeitschrift
9

Files

https://pubs.rsc.org/en/content/articlepdf/2019/ra/c9ra04158c https://europepmc.org/articles/PMC9070672?pdf=render

Data source: Europe PubMed Central

Abstract
A solvent extract of the soft coral Sarcophyton ehrenbergi afforded cembrene diterpenoids, sarcoehrenbergilid D-F (1-3). Chemical structures were established by modern spectroscopic techniques with absolute stereochemistries determined by circular dichroism (CD) and time-dependent density functional theory electronic CD calculations (TDDFT-ECD). Cytotoxicity activities for 1-3 were evaluated against three human cancer cell lines: lung (A549), colon (Caco-2) and liver (HepG2).
Date of acceptance
2019
Autoren
  • Mohamed-Elamir F Hegazy
  • Tarik A Mohamed
  • Abdelsamed I Elshamy
  • Ahmed R Hamed
  • Mahmoud AA Ibrahim
  • Shinji Ohta
  • Akemi Umeyama
  • Paul W Paré
  • Thomas Efferth
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/35529183
DOI
10.1039/c9ra04158c
eISSN
2046-2069
Externe Identifier
  • PubMed Central ID: PMC9070672
Ausgabe der Veröffentlichung
47
Zeitschrift
RSC Adv
Sprache
eng
Country
England
Paginierung
27183 - 27189
PII
c9ra04158c
Datum der Veröffentlichung
2019
Status
Published online
Titel
Sarcoehrenbergilides D-F: cytotoxic cembrene diterpenoids from the soft coral Sarcophyton ehrenbergi.
Sub types
  • Journal Article
Ausgabe der Zeitschrift
9

Data source: PubMed

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