IMMUNOHISTOCHEMICAL DETECTION OF THE MULTI-DRUG-RESISTANCE MARKER P-GLYCOPROTEIN IN UTERINE CERVICAL CARCINOMAS AND NORMAL CERVICAL TISSUE

Publication type:
Journal article
Metadata:
Autoren
  • J SCHNEIDER
  • T EFFERTH
  • J MATTERN
  • FJ RODRIGUEZESCUDERO
  • M VOLM
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:A1992HJ88500009&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.1016/0002-9378(92)91341-7
Externe Identifier
  • Clarivate Analytics Document Solution ID: HJ885
  • PubMed Identifier: 1372471
ISSN
0002-9378
Ausgabe der Veröffentlichung
3
Zeitschrift
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
Schlüsselwörter
  • P-GLYCOPROTEIN
  • CARCINOMA
  • UTERUS
  • CERVIX
Paginierung
825 - 829
Datum der Veröffentlichung
1992
Status
Published
Titel
IMMUNOHISTOCHEMICAL DETECTION OF THE MULTI-DRUG-RESISTANCE MARKER P-GLYCOPROTEIN IN UTERINE CERVICAL CARCINOMAS AND NORMAL CERVICAL TISSUE
Sub types
  • Article
Ausgabe der Zeitschrift
166

Data source: Web of Science (Lite)

Other metadata sources:
Autoren
  • José Schneider
  • Thomas Efferth
  • Jürgen Mattern
  • Francisco-Javier Rodriguez-Escudero
  • Manfred Volm
DOI
10.1016/0002-9378(92)91341-7
ISSN
0002-9378
Ausgabe der Veröffentlichung
3
Zeitschrift
American Journal of Obstetrics and Gynecology
Sprache
en
Paginierung
825 - 829
Datum der Veröffentlichung
1992
Status
Published
Herausgeber
Elsevier BV
Herausgeber URL
http://dx.doi.org/10.1016/0002-9378(92)91341-7
Datum der Datenerfassung
2018
Titel
Immunohistochemical detection of the multi-drug-resistance marker P-glycoprotein in uterine cervical carcinomas and normal cervical tissue
Ausgabe der Zeitschrift
166

Data source: Crossref

Abstract
Uterine cervical carcinomas and normal cervical tissue (controls) were investigated for the presence of the multi-drug-resistance gene product P-glycoprotein by means of immunohistochemistry, with the C219 monoclonal antibody and the streptavidin-biotin-peroxidase technique. Ten of 11 cervical carcinomas, 2 of which were previously treated with chemotherapeutic agents of the multi-drug-resistance group, showed a positive reaction of tumor cells. All normal controls showed a positive reaction of the ectocervical and endocervical epithelial cells. P-glycoprotein seems to be implicated at least in part in resistance to chemotherapy of cervical carcinoma.
Addresses
  • University of the Basque Country, Hospital de Cruces, Bilbao, Spain.
Autoren
  • J Schneider
  • T Efferth
  • T Efferth
  • J Mattern
  • FJ Rodriguez-Escudero
  • M Volm
DOI
10.1016/0002-9378(92)91341-7
eISSN
1097-6868
Externe Identifier
  • PubMed Identifier: 1372471
Open access
false
ISSN
0002-9378
Ausgabe der Veröffentlichung
3
Zeitschrift
American journal of obstetrics and gynecology
Schlüsselwörter
  • Cervix Uteri
  • Humans
  • Carcinoma
  • Cisplatin
  • Vindesine
  • Bleomycin
  • Membrane Glycoproteins
  • Antineoplastic Combined Chemotherapy Protocols
  • Antibodies, Monoclonal
  • Immunohistochemistry
  • Tissue Distribution
  • Drug Resistance
  • Reference Values
  • Uterine Cervical Neoplasms
  • Female
  • Biomarkers
  • ATP Binding Cassette Transporter, Subfamily B, Member 1
Sprache
eng
Medium
Print
Paginierung
825 - 829
Datum der Veröffentlichung
1992
Status
Published
Datum der Datenerfassung
1992
Titel
Immunohistochemical detection of the multi-drug-resistance marker P-glycoprotein in uterine cervical carcinomas and normal cervical tissue.
Sub types
  • Research Support, Non-U.S. Gov't
  • Journal Article
Ausgabe der Zeitschrift
166

Data source: Europe PubMed Central

Abstract
Uterine cervical carcinomas and normal cervical tissue (controls) were investigated for the presence of the multi-drug-resistance gene product P-glycoprotein by means of immunohistochemistry, with the C219 monoclonal antibody and the streptavidin-biotin-peroxidase technique. Ten of 11 cervical carcinomas, 2 of which were previously treated with chemotherapeutic agents of the multi-drug-resistance group, showed a positive reaction of tumor cells. All normal controls showed a positive reaction of the ectocervical and endocervical epithelial cells. P-glycoprotein seems to be implicated at least in part in resistance to chemotherapy of cervical carcinoma.
Autoren
  • J Schneider
  • T Efferth
  • J Mattern
  • FJ Rodriguez-Escudero
  • M Volm
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/1372471
DOI
10.1016/0002-9378(92)91341-7
ISSN
0002-9378
Ausgabe der Veröffentlichung
3
Zeitschrift
Am J Obstet Gynecol
Schlüsselwörter
  • ATP Binding Cassette Transporter, Subfamily B, Member 1
  • Antibodies, Monoclonal
  • Antineoplastic Combined Chemotherapy Protocols
  • Biomarkers
  • Bleomycin
  • Carcinoma
  • Cervix Uteri
  • Cisplatin
  • Drug Resistance
  • Female
  • Humans
  • Immunohistochemistry
  • Membrane Glycoproteins
  • Reference Values
  • Tissue Distribution
  • Uterine Cervical Neoplasms
  • Vindesine
Sprache
eng
Country
United States
Paginierung
825 - 829
PII
0002-9378(92)91341-7
Datum der Veröffentlichung
1992
Status
Published
Datum, an dem der Datensatz öffentlich gemacht wurde
1992
Titel
Immunohistochemical detection of the multi-drug-resistance marker P-glycoprotein in uterine cervical carcinomas and normal cervical tissue.
Sub types
  • Journal Article
  • Research Support, Non-U.S. Gov't
Ausgabe der Zeitschrift
166

Data source: PubMed

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