REVERSAL OF INHERENT MULTIDRUG-RESISTANCE IN PRIMARY HUMAN RENAL-CELL CARCINOMA CELL-CULTURES BY S-9788

Publication type:
Journal article
Metadata:
Autoren
  • T EFFERTH
  • TA DUNN
  • M BERLION
  • H LANGENBAHN
  • EW POMMERENKE
  • M VOLM
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:A1993LR81300014&DestLinkType=FullRecord&DestApp=WOS_CPL
Externe Identifier
  • Clarivate Analytics Document Solution ID: LR813
  • PubMed Identifier: 8102519
ISSN
0250-7005
Ausgabe der Veröffentlichung
4
Zeitschrift
ANTICANCER RESEARCH
Schlüsselwörter
  • S-9788
  • MULTIDRUG-RESISTANCE
  • P-GLYCOPROTEIN
  • HUMAN RENAL CELL CARCINOMA
Paginierung
905 - 908
Datum der Veröffentlichung
1993
Status
Published
Titel
REVERSAL OF INHERENT MULTIDRUG-RESISTANCE IN PRIMARY HUMAN RENAL-CELL CARCINOMA CELL-CULTURES BY S-9788
Sub types
  • Article
Ausgabe der Zeitschrift
13

Data source: Web of Science (Lite)

Other metadata sources:
Abstract
In a panel of 14 primary cultures of human renal cell carcinomas the reversal of inherent multidrug-resistance by S 9788, a new triazinoaminopiperidine derivative, was analysed. In combination with doxorubicin S 9788 revealed an evident reversal of multidrug resistance in 12 cell cultures. Two cell cultures remained unaffected. An association between reversal and P-glycoprotein (P-170) expression suggests that S 9788 exerts its activity through P-glycoprotein.
Addresses
  • German Cancer Research Center, Heidelberg.
Autoren
  • T Efferth
  • TA Dunn
  • M Berlion
  • H Langenbahn
  • EW Pommerenke
  • M Volm
eISSN
1791-7530
Externe Identifier
  • PubMed Identifier: 8102519
Open access
false
ISSN
0250-7005
Ausgabe der Veröffentlichung
4
Zeitschrift
Anticancer research
Schlüsselwörter
  • Tumor Cells, Cultured
  • Animals
  • Humans
  • Mice
  • Sarcoma 180
  • Carcinoma, Renal Cell
  • Kidney Neoplasms
  • Piperidines
  • Triazines
  • Doxorubicin
  • Carrier Proteins
  • Membrane Glycoproteins
  • Antineoplastic Agents
  • Cell Division
  • Dose-Response Relationship, Drug
  • Drug Interactions
  • Drug Resistance
  • Kinetics
  • ATP Binding Cassette Transporter, Subfamily B, Member 1
Sprache
eng
Medium
Print
Paginierung
905 - 908
Datum der Veröffentlichung
1993
Status
Published
Datum der Datenerfassung
1993
Titel
Reversal of inherent multidrug-resistance in primary human renal cell carcinoma cell cultures by S 9788.
Sub types
  • Journal Article
Ausgabe der Zeitschrift
13

Data source: Europe PubMed Central

Abstract
In a panel of 14 primary cultures of human renal cell carcinomas the reversal of inherent multidrug-resistance by S 9788, a new triazinoaminopiperidine derivative, was analysed. In combination with doxorubicin S 9788 revealed an evident reversal of multidrug resistance in 12 cell cultures. Two cell cultures remained unaffected. An association between reversal and P-glycoprotein (P-170) expression suggests that S 9788 exerts its activity through P-glycoprotein.
Autoren
  • T Efferth
  • TA Dunn
  • M Berlion
  • H Langenbahn
  • EW Pommerenke
  • M Volm
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/8102519
ISSN
0250-7005
Ausgabe der Veröffentlichung
4
Zeitschrift
Anticancer Res
Schlüsselwörter
  • ATP Binding Cassette Transporter, Subfamily B, Member 1
  • Animals
  • Antineoplastic Agents
  • Carcinoma, Renal Cell
  • Carrier Proteins
  • Cell Division
  • Dose-Response Relationship, Drug
  • Doxorubicin
  • Drug Interactions
  • Drug Resistance
  • Humans
  • Kidney Neoplasms
  • Kinetics
  • Membrane Glycoproteins
  • Mice
  • Piperidines
  • Sarcoma 180
  • Triazines
  • Tumor Cells, Cultured
Sprache
eng
Country
Greece
Paginierung
905 - 908
Datum der Veröffentlichung
1993
Status
Published
Datum, an dem der Datensatz öffentlich gemacht wurde
1993
Titel
Reversal of inherent multidrug-resistance in primary human renal cell carcinoma cell cultures by S 9788.
Sub types
  • Journal Article
Ausgabe der Zeitschrift
13

Data source: PubMed

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