Chemotherapy-induced resistance by ATP-binding cassette transporter genes
- Publication type:
- Journal article
- Metadata:
-
- Autoren
- Jean-Pierre Gillet
- Thomas Efferth
- Jose Remacle
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000247858100001&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1016/j.bbcan.2007.05.002
- eISSN
- 1879-2561
- Externe Identifier
- Clarivate Analytics Document Solution ID: 187OR
- PubMed Identifier: 17572300
- ISSN
- 0304-419X
- Ausgabe der Veröffentlichung
- 2
- Zeitschrift
- BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Schlüsselwörter
- ABC transporter genes
- multidrug resistance
- Paginierung
- 237 - 262
- Datum der Veröffentlichung
- 2007
- Status
- Published
- Titel
- Chemotherapy-induced resistance by ATP-binding cassette transporter genes
- Sub types
- Review
- Ausgabe der Zeitschrift
- 1775
Data source: Web of Science (Lite)
- Other metadata sources:
-
- Autoren
- J GILLET
- T EFFERTH
- J REMACLE
- DOI
- 10.1016/j.bbcan.2007.05.002
- ISSN
- 0304-419X
- Ausgabe der Veröffentlichung
- 2
- Zeitschrift
- Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
- Sprache
- en
- Paginierung
- 237 - 262
- Datum der Veröffentlichung
- 2007
- Status
- Published
- Herausgeber
- Elsevier BV
- Herausgeber URL
- http://dx.doi.org/10.1016/j.bbcan.2007.05.002
- Datum der Datenerfassung
- 2019
- Titel
- Chemotherapy-induced resistance by ATP-binding cassette transporter genes
- Ausgabe der Zeitschrift
- 1775
Data source: Crossref
- Abstract
- A key issue in the treatment of many cancers is the development of resistance to chemotherapeutic drugs. Resistance mechanisms are numerous and complex. One of them is mediated by the overexpression of ATP-binding cassette (ABC) transporters able to efflux drugs out of the tumor cell. The last two decades have seen notable growth of knowledge concerning the involvement of ABC transporters in resistance to chemotherapy. This review emphasizes these transporters, their clinical relevance and the diagnostic methods and strategies to circumvent multidrug resistance (MDR) mediated by ABC transporters.
- Addresses
- Department of Biology, University of Namur, 61 rue de Bruxelles, 5000 Namur, Belgium. gilletjp@mail.nih.gov
- Autoren
- Jean-Pierre Gillet
- Thomas Efferth
- Thomas Efferth
- José Remacle
- DOI
- 10.1016/j.bbcan.2007.05.002
- eISSN
- 1878-2434
- Externe Identifier
- PubMed Identifier: 17572300
- Open access
- false
- ISSN
- 0006-3002
- Ausgabe der Veröffentlichung
- 2
- Zeitschrift
- Biochimica et biophysica acta
- Schlüsselwörter
- Stem Cells
- Humans
- Neoplasms
- ATP-Binding Cassette Transporters
- Antineoplastic Agents
- Crystallography, X-Ray
- Protein Conformation
- Drug Resistance
- Genetic Therapy
- Sprache
- eng
- Medium
- Print-Electronic
- Online publication date
- 2007
- Paginierung
- 237 - 262
- Datum der Veröffentlichung
- 2007
- Status
- Published
- Datum der Datenerfassung
- 2007
- Titel
- Chemotherapy-induced resistance by ATP-binding cassette transporter genes.
- Sub types
- Review
- Journal Article
- Ausgabe der Zeitschrift
- 1775
Data source: Europe PubMed Central
- Abstract
- A key issue in the treatment of many cancers is the development of resistance to chemotherapeutic drugs. Resistance mechanisms are numerous and complex. One of them is mediated by the overexpression of ATP-binding cassette (ABC) transporters able to efflux drugs out of the tumor cell. The last two decades have seen notable growth of knowledge concerning the involvement of ABC transporters in resistance to chemotherapy. This review emphasizes these transporters, their clinical relevance and the diagnostic methods and strategies to circumvent multidrug resistance (MDR) mediated by ABC transporters.
- Date of acceptance
- 2007
- Autoren
- Jean-Pierre Gillet
- Thomas Efferth
- José Remacle
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/17572300
- DOI
- 10.1016/j.bbcan.2007.05.002
- ISSN
- 0006-3002
- Ausgabe der Veröffentlichung
- 2
- Zeitschrift
- Biochim Biophys Acta
- Schlüsselwörter
- ATP-Binding Cassette Transporters
- Antineoplastic Agents
- Crystallography, X-Ray
- Drug Resistance
- Genetic Therapy
- Humans
- Neoplasms
- Protein Conformation
- Stem Cells
- Sprache
- eng
- Country
- Netherlands
- Paginierung
- 237 - 262
- PII
- S0304-419X(07)00005-4
- Datum der Veröffentlichung
- 2007
- Status
- Published
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2007
- Titel
- Chemotherapy-induced resistance by ATP-binding cassette transporter genes.
- Sub types
- Journal Article
- Review
- Ausgabe der Zeitschrift
- 1775
Data source: PubMed
- Beziehungen:
- Property of