Molecular target-guided tumor therapy with natural products derived from traditional Chinese medicine

Publication type:
Journal article
Metadata:
Autoren
  • Thomas Efferth
  • Yu-jie Fu
  • Yuan-gang Zu
  • Guenter Schwarz
  • Venkata Sai Badireenath Konkimalla
  • Michael Wink
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000248203400002&DestLinkType=FullRecord&DestApp=WOS_CPL
eISSN
1875-533X
Externe Identifier
  • Clarivate Analytics Document Solution ID: 192LN
  • PubMed Identifier: 17691944
ISSN
0929-8673
Ausgabe der Veröffentlichung
19
Zeitschrift
CURRENT MEDICINAL CHEMISTRY
Schlüsselwörter
  • phytochemistry
  • pharmacognosy
  • phytomedicine
  • biotechnology
  • pharmacogenomics
Paginierung
2024 - 2032
Datum der Veröffentlichung
2007
Status
Published
Titel
Molecular target-guided tumor therapy with natural products derived from traditional Chinese medicine
Sub types
  • Review
Ausgabe der Zeitschrift
14

Data source: Web of Science (Lite)

Other metadata sources:
Autoren
  • Thomas Efferth
  • Yu-jie Fu
  • Yuan-gang Zu
  • Gunter Schwarz
  • Venkata Sai Badireenath Konkimalla
  • Michael Wink
DOI
10.2174/092986707781368441
ISSN
0929-8673
Ausgabe der Veröffentlichung
19
Zeitschrift
Current Medicinal Chemistry
Sprache
en
Paginierung
2024 - 2032
Datum der Veröffentlichung
2007
Status
Published
Herausgeber
Bentham Science Publishers Ltd.
Herausgeber URL
http://dx.doi.org/10.2174/092986707781368441
Datum der Datenerfassung
2017
Titel
Molecular Target-Guided Tumor Therapy with Natural Products Derived from Traditional Chinese Medicine
Ausgabe der Zeitschrift
14

Data source: Crossref

Abstract
A tremendous interest exists in the Western world in Traditional Chinese Medicine (TCM) with rapidly increasing export rates of TCM products from China to Europe and USA. This led to a national decision of the Chinese government to implement a "Plan for the Modernization of Chinese Medicine". Concerning the use of Chinese medicinal herbs, two major directions can be distinguished. One field is phytochemistry and pharmacognosy. Secondary metabolites isolated from Chinese plants can be easily subjected to pharmacological, molecular biological, and pharmacogenomic analyses using methods of modern cell and molecular biology as exemplified for camptothecin from Camptotheca acuminata in the present review. The second field of interest is phytomedicine. Standardized international quality guidelines help to improve quality, safety and efficacy of Chinese medicinal herbs. Sustainability of natural products from TCM can be reached by breeding high-yield varieties or by biotechnological approaches. In the long term, natural products from TCM can contribute to the development of molecular target-guided therapies and individualized treatment strategies.
Addresses
  • German Cancer Research Center, Pharmaceutical Biology (C015), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany. t.efferth@dkfz.de
Autoren
  • Thomas Efferth
  • Thomas Efferth
  • Yu-Jie Fu
  • Yuan-Gang Zu
  • Günter Schwarz
  • Venkata Sai Badireenath Konkimalla
  • Michael Wink
DOI
10.2174/092986707781368441
eISSN
1875-533X
Externe Identifier
  • PubMed Identifier: 17691944
Open access
false
ISSN
0929-8673
Ausgabe der Veröffentlichung
19
Zeitschrift
Current medicinal chemistry
Schlüsselwörter
  • Humans
  • Neoplasms
  • Camptothecin
  • Antineoplastic Agents, Phytogenic
  • Medicine, Chinese Traditional
  • Pharmacognosy
  • Pharmacogenetics
Sprache
eng
Medium
Print
Paginierung
2024 - 2032
Datum der Veröffentlichung
2007
Status
Published
Datum der Datenerfassung
2007
Titel
Molecular target-guided tumor therapy with natural products derived from traditional Chinese medicine.
Sub types
  • Research Support, Non-U.S. Gov't
  • Review
  • Journal Article
Ausgabe der Zeitschrift
14

Data source: Europe PubMed Central

Abstract
A tremendous interest exists in the Western world in Traditional Chinese Medicine (TCM) with rapidly increasing export rates of TCM products from China to Europe and USA. This led to a national decision of the Chinese government to implement a "Plan for the Modernization of Chinese Medicine". Concerning the use of Chinese medicinal herbs, two major directions can be distinguished. One field is phytochemistry and pharmacognosy. Secondary metabolites isolated from Chinese plants can be easily subjected to pharmacological, molecular biological, and pharmacogenomic analyses using methods of modern cell and molecular biology as exemplified for camptothecin from Camptotheca acuminata in the present review. The second field of interest is phytomedicine. Standardized international quality guidelines help to improve quality, safety and efficacy of Chinese medicinal herbs. Sustainability of natural products from TCM can be reached by breeding high-yield varieties or by biotechnological approaches. In the long term, natural products from TCM can contribute to the development of molecular target-guided therapies and individualized treatment strategies.
Autoren
  • Thomas Efferth
  • Yu-Jie Fu
  • Yuan-Gang Zu
  • Günter Schwarz
  • Venkata Sai Badireenath Konkimalla
  • Michael Wink
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/17691944
DOI
10.2174/092986707781368441
ISSN
0929-8673
Ausgabe der Veröffentlichung
19
Zeitschrift
Curr Med Chem
Schlüsselwörter
  • Antineoplastic Agents, Phytogenic
  • Camptothecin
  • Humans
  • Medicine, Chinese Traditional
  • Neoplasms
  • Pharmacogenetics
  • Pharmacognosy
Sprache
eng
Country
United Arab Emirates
Paginierung
2024 - 2032
Datum der Veröffentlichung
2007
Status
Published
Datum, an dem der Datensatz öffentlich gemacht wurde
2007
Titel
Molecular target-guided tumor therapy with natural products derived from traditional Chinese medicine.
Sub types
  • Journal Article
  • Research Support, Non-U.S. Gov't
  • Review
Ausgabe der Zeitschrift
14

Data source: PubMed

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