Artesunate as a potent antiviral agent in a patient with late drug-resistant cytomegalovirus infection after hematopoietic stem cell transplantation
- Publication type:
- Journal article
- Metadata:
-
- Autoren
- Michael Y Shapira
- Igor B Resnick
- Sunwen Chou
- Avidan U Neumann
- Nell S Lurain
- Thomas Stamminger
- Orit Caplan
- Niveen Saleh
- Thomas Efferth
- Manfred Marschall
- Dana G Wolf
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000254784300023&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1086/587106
- Externe Identifier
- Clarivate Analytics Document Solution ID: 285NU
- PubMed Identifier: 18419454
- ISSN
- 1058-4838
- Ausgabe der Veröffentlichung
- 9
- Zeitschrift
- CLINICAL INFECTIOUS DISEASES
- Paginierung
- 1455 - 1457
- Datum der Veröffentlichung
- 2008
- Status
- Published
- Titel
- Artesunate as a potent antiviral agent in a patient with late drug-resistant cytomegalovirus infection after hematopoietic stem cell transplantation
- Sub types
- Editorial Material
- Ausgabe der Zeitschrift
- 46
Data source: Web of Science (Lite)
- Other metadata sources:
-
- Autoren
- Michael Y Shapira
- Igor B Resnick
- Sunwen Chou
- Avidan U Neumann
- Nell S Lurain
- Thomas Stamminger
- Orit Caplan
- Niveen Saleh
- Thomas Efferth
- Manfred Marschall
- Dana G Wolf
- DOI
- 10.1086/587106
- eISSN
- 1537-6591
- ISSN
- 1058-4838
- Ausgabe der Veröffentlichung
- 9
- Zeitschrift
- Clinical Infectious Diseases
- Sprache
- en
- Paginierung
- 1455 - 1457
- Datum der Veröffentlichung
- 2008
- Status
- Published
- Herausgeber
- Oxford University Press (OUP)
- Herausgeber URL
- http://dx.doi.org/10.1086/587106
- Datum der Datenerfassung
- 2017
- Titel
- Artesunate as a Potent Antiviral Agent in a Patient with Late Drug‐Resistant Cytomegalovirus Infection after Hematopoietic Stem Cell Transplantation
- Ausgabe der Zeitschrift
- 46
Data source: Crossref
- Abstract
- This is the first report of treatment of cytomegalovirus infection with artesunate, for a stem cell transplant recipient with a newly identified foscarnet-resistant and ganciclovir-resistant DNA polymerase L776M mutation. Artesunate treatment resulted in a 1.7-2.1-log reduction in viral load by treatment day 7, with a viral half-life of 0.9-1.9 days, indicating a highly effective block in viral replication.
- Addresses
- Hadassah Hebrew University Medical Center, Jerusalem, Israel.
- Autoren
- Michael Y Shapira
- Igor B Resnick
- Sunwen Chou
- Avidan U Neumann
- Nell S Lurain
- Thomas Stamminger
- Orit Caplan
- Niveen Saleh
- Thomas Efferth
- Thomas Efferth
- Manfred Marschall
- Dana G Wolf
- DOI
- 10.1086/587106
- eISSN
- 1537-6591
- Externe Identifier
- PubMed Identifier: 18419454
- Funding acknowledgements
- NIAID NIH HHS: AI39938
- Open access
- false
- ISSN
- 1058-4838
- Ausgabe der Veröffentlichung
- 9
- Zeitschrift
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
- Schlüsselwörter
- Humans
- Cytomegalovirus
- Cytomegalovirus Infections
- Foscarnet
- Artemisinins
- Antiviral Agents
- Treatment Outcome
- Hematopoietic Stem Cell Transplantation
- Drug Resistance, Viral
- Child
- Male
- Artesunate
- Sprache
- eng
- Medium
- Paginierung
- 1455 - 1457
- Datum der Veröffentlichung
- 2008
- Status
- Published
- Datum der Datenerfassung
- 2008
- Titel
- Artesunate as a potent antiviral agent in a patient with late drug-resistant cytomegalovirus infection after hematopoietic stem cell transplantation.
- Sub types
- Research Support, Non-U.S. Gov't
- Journal Article
- Case Reports
- Research Support, N.I.H., Extramural
- Ausgabe der Zeitschrift
- 46
Data source: Europe PubMed Central
- Abstract
- This is the first report of treatment of cytomegalovirus infection with artesunate, for a stem cell transplant recipient with a newly identified foscarnet-resistant and ganciclovir-resistant DNA polymerase L776M mutation. Artesunate treatment resulted in a 1.7-2.1-log reduction in viral load by treatment day 7, with a viral half-life of 0.9-1.9 days, indicating a highly effective block in viral replication.
- Autoren
- Michael Y Shapira
- Igor B Resnick
- Sunwen Chou
- Avidan U Neumann
- Nell S Lurain
- Thomas Stamminger
- Orit Caplan
- Niveen Saleh
- Thomas Efferth
- Manfred Marschall
- Dana G Wolf
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/18419454
- DOI
- 10.1086/587106
- eISSN
- 1537-6591
- Funding acknowledgements
- NIAID NIH HHS: AI39938
- Ausgabe der Veröffentlichung
- 9
- Zeitschrift
- Clin Infect Dis
- Schlüsselwörter
- Antiviral Agents
- Artemisinins
- Artesunate
- Child
- Cytomegalovirus
- Cytomegalovirus Infections
- Drug Resistance, Viral
- Foscarnet
- Hematopoietic Stem Cell Transplantation
- Humans
- Male
- Treatment Outcome
- Sprache
- eng
- Country
- United States
- Paginierung
- 1455 - 1457
- Datum der Veröffentlichung
- 2008
- Status
- Published
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2008
- Titel
- Artesunate as a potent antiviral agent in a patient with late drug-resistant cytomegalovirus infection after hematopoietic stem cell transplantation.
- Sub types
- Case Reports
- Journal Article
- Research Support, N.I.H., Extramural
- Research Support, Non-U.S. Gov't
- Ausgabe der Zeitschrift
- 46
Data source: PubMed
- Beziehungen:
- Property of