Cameroonian medicinal plants: pharmacology and derived natural products

Publication type:
Journal article
Metadata:
Autoren
  • Victor Kuete
  • Thomas Efferth
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000209177100023&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.3389/fphar.2010.00123
Externe Identifier
  • Clarivate Analytics Document Solution ID: V35WY
  • PubMed Identifier: 21833168
ISSN
1663-9812
Zeitschrift
FRONTIERS IN PHARMACOLOGY
Schlüsselwörter
  • medicinal plants
  • ethnopharmacology
  • Africa
Artikelnummer
ARTN 123
Datum der Veröffentlichung
2010
Status
Published
Titel
Cameroonian medicinal plants: pharmacology and derived natural products
Sub types
  • Review
Ausgabe der Zeitschrift
1

Data source: Web of Science (Lite)

Other metadata sources:
Autoren
  • Victor Kuete
  • Thomas Efferth
DOI
10.3389/fphar.2010.00123
eISSN
1663-9812
Zeitschrift
Frontiers in Pharmacology
Online publication date
2010
Status
Published online
Herausgeber
Frontiers Media SA
Herausgeber URL
http://dx.doi.org/10.3389/fphar.2010.00123
Datum der Datenerfassung
2015
Titel
Cameroonian Medicinal Plants: Pharmacology and Derived Natural Products
Ausgabe der Zeitschrift
1

Data source: Crossref

Abstract
Many developing countries including Cameroon have mortality patterns that reflect high levels of infectious diseases and the risk of death during pregnancy and childbirth, in addition to cancers, cardiovascular diseases and chronic respiratory diseases that account for most deaths in the developed world. Several medicinal plants are used traditionally for their treatment. In this review, plants used in Cameroonian traditional medicine with evidence for the activities of their crude extracts and/or derived products have been discussed. A considerable number of plant extracts and isolated compounds possess significant antimicrobial, anti-parasitic including antimalarial, anti-proliferative, anti-inflammatory, anti-diabetes, and antioxidant effects. Most of the biologically active compounds belong to terpenoids, phenolics, and alkaloids. Terpenoids from Cameroonian plants showed best activities as anti-parasitic, but rather poor antimicrobial effects. The best antimicrobial, anti-proliferative, and antioxidant compounds were phenolics. In conclusion, many medicinal plants traditionally used in Cameroon to treat various ailments displayed good activities in vitro. This explains the endeavor of Cameroonian research institutes in drug discovery from indigenous medicinal plants. However, much work is still to be done to standardize methodologies and to study the mechanisms of action of isolated natural products.
Addresses
  • Department of Biochemistry, Faculty of Science, University of Dschang Dschang, Cameroon.
Autoren
DOI
10.3389/fphar.2010.00123
eISSN
1663-9812
Externe Identifier
  • PubMed Identifier: 21833168
  • PubMed Central ID: PMC3153003
Open access
true
ISSN
1663-9812
Zeitschrift
Frontiers in pharmacology
Sprache
eng
Medium
Electronic-eCollection
Online publication date
2010
Open access status
Open Access
Paginierung
123
Datum der Veröffentlichung
2010
Status
Published
Datum der Datenerfassung
2011
Titel
Cameroonian medicinal plants: pharmacology and derived natural products.
Sub types
  • review-article
  • Journal Article
Ausgabe der Zeitschrift
1

Files

https://www.frontiersin.org/articles/10.3389/fphar.2010.00123/pdf https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21833168/pdf/?tool=EBI https://europepmc.org/articles/PMC3153003?pdf=render

Data source: Europe PubMed Central

Abstract
Many developing countries including Cameroon have mortality patterns that reflect high levels of infectious diseases and the risk of death during pregnancy and childbirth, in addition to cancers, cardiovascular diseases and chronic respiratory diseases that account for most deaths in the developed world. Several medicinal plants are used traditionally for their treatment. In this review, plants used in Cameroonian traditional medicine with evidence for the activities of their crude extracts and/or derived products have been discussed. A considerable number of plant extracts and isolated compounds possess significant antimicrobial, anti-parasitic including antimalarial, anti-proliferative, anti-inflammatory, anti-diabetes, and antioxidant effects. Most of the biologically active compounds belong to terpenoids, phenolics, and alkaloids. Terpenoids from Cameroonian plants showed best activities as anti-parasitic, but rather poor antimicrobial effects. The best antimicrobial, anti-proliferative, and antioxidant compounds were phenolics. In conclusion, many medicinal plants traditionally used in Cameroon to treat various ailments displayed good activities in vitro. This explains the endeavor of Cameroonian research institutes in drug discovery from indigenous medicinal plants. However, much work is still to be done to standardize methodologies and to study the mechanisms of action of isolated natural products.
Date of acceptance
2010
Autoren
  • Victor Kuete
  • Thomas Efferth
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/21833168
DOI
10.3389/fphar.2010.00123
eISSN
1663-9812
Externe Identifier
  • PubMed Central ID: PMC3153003
Zeitschrift
Front Pharmacol
Schlüsselwörter
  • Africa
  • ethnopharmacology
  • medicinal plants
Sprache
eng
Country
Switzerland
Paginierung
123
Datum der Veröffentlichung
2010
Status
Published online
Datum, an dem der Datensatz öffentlich gemacht wurde
2011
Titel
Cameroonian medicinal plants: pharmacology and derived natural products.
Sub types
  • Journal Article
Ausgabe der Zeitschrift
1

Data source: PubMed

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