Activities of Ten Essential Oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 Cancer Cells
- Publication type:
- Journal article
- Metadata:
-
- Autoren
- Yuangang Zu
- Huimin Yu
- Lu Liang
- Yujie Fu
- Thomas Efferth
- Xia Liu
- Nan Wu
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000278105400017&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.3390/molecules15053200
- Externe Identifier
- Clarivate Analytics Document Solution ID: 601YY
- PubMed Identifier: 20657472
- ISSN
- 1420-3049
- Ausgabe der Veröffentlichung
- 5
- Zeitschrift
- MOLECULES
- Schlüsselwörter
- essential oils
- activities
- Propionibacterium acnes
- cytotoxicity
- cancer cell lines
- Paginierung
- 3200 - 3210
- Datum der Veröffentlichung
- 2010
- Status
- Published
- Titel
- Activities of Ten Essential Oils towards <i>Propionibacterium acnes</i> and PC-3, A-549 and MCF-7 Cancer Cells
- Sub types
- Article
- Ausgabe der Zeitschrift
- 15
Data source: Web of Science (Lite)
- Other metadata sources:
-
- Autoren
- Yuangang Zu
- Huimin Yu
- Lu Liang
- Yujie Fu
- Thomas Efferth
- Xia Liu
- Nan Wu
- DOI
- 10.3390/molecules15053200
- eISSN
- 1420-3049
- Ausgabe der Veröffentlichung
- 5
- Zeitschrift
- Molecules
- Sprache
- en
- Online publication date
- 2010
- Paginierung
- 3200 - 3210
- Status
- Published online
- Herausgeber
- MDPI AG
- Herausgeber URL
- http://dx.doi.org/10.3390/molecules15053200
- Datum der Datenerfassung
- 2018
- Titel
- Activities of Ten Essential Oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 Cancer Cells
- Ausgabe der Zeitschrift
- 15
Data source: Crossref
- Abstract
- Ten essential oils, namely, mint (Mentha spicata L., Lamiaceae), ginger (Zingiber officinale Rosc., Zingiberaceae), lemon (Citrus limon Burm.f., Rutaceae), grapefruit (Citrus paradisi Macf., Rutaceae), jasmine (Jasminum grandiflora L., Oleaceae), lavender (Mill., Lamiaceae), chamomile (Matricaria chamomilla L., Compositae), thyme (Thymus vulgaris L., Lamiaceae), rose (Rosa damascena Mill., Rosaceae) and cinnamon (Cinnamomum zeylanicum N. Lauraceae) were tested for their antibacterial activities towards Propionibacterium acnes and in vitro toxicology against three human cancer cell lines. Thyme, cinnamon and rose essential oils exhibited the best antibacterial activities towards P. acnes, with inhibition diameters of 40 +/- 1.2 mm, 33.5 +/- 1.5 mm and 16.5 +/- 0.7 mm, and minimal inhibitory concentrations of 0.016% (v/v), 0.016% (v/v) and 0.031% (v/v), respectively. Time-kill dynamic procedures showed that thyme, cinnamon, rose, and lavender essential oils exhibited the strongest bactericidal activities at a concentration of 0.25% (v/v), and P. acnes was completely killed after 5 min. The thyme essential oil exhibited the strongest cytotoxicity towards three human cancer cells. Its inhibition concentration 50% (IC(50)) values on PC-3, A549 and MCF-7 tumor cell lines were 0.010% (v/v), 0.011% (v/v) and 0.030% (v/v), respectively. The cytotoxicity of 10 essential oils on human prostate carcinoma cell (PC-3) was significantly stronger than on human lung carcinoma (A549) and human breast cancer (MCF-7) cell lines.
- Addresses
- Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, China. zygorl@vip.hl.cn
- Autoren
- Yuangang Zu
- Huimin Yu
- Lu Liang
- Yujie Fu
- Thomas Efferth
- Thomas Efferth
- Xia Liu
- Nan Wu
- DOI
- 10.3390/molecules15053200
- eISSN
- 1420-3049
- Externe Identifier
- PubMed Identifier: 20657472
- PubMed Central ID: PMC6263286
- Open access
- true
- ISSN
- 1420-3049
- Ausgabe der Veröffentlichung
- 5
- Zeitschrift
- Molecules (Basel, Switzerland)
- Schlüsselwörter
- Cell Line, Tumor
- Humans
- Propionibacterium acnes
- Neoplasms
- Oils, Volatile
- Antineoplastic Agents
- Anti-Bacterial Agents
- Microbial Sensitivity Tests
- Female
- Male
- Sprache
- eng
- Medium
- Electronic
- Online publication date
- 2010
- Open access status
- Open Access
- Paginierung
- 3200 - 3210
- Datum der Veröffentlichung
- 2010
- Status
- Published
- Publisher licence
- CC BY
- Datum der Datenerfassung
- 2010
- Titel
- Activities of ten essential oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 cancer cells.
- Sub types
- Research Support, Non-U.S. Gov't
- research-article
- Journal Article
- Ausgabe der Zeitschrift
- 15
Files
https://www.mdpi.com/1420-3049/15/5/3200/pdf?version=1403112754 https://europepmc.org/articles/PMC6263286?pdf=render
Data source: Europe PubMed Central
- Abstract
- Ten essential oils, namely, mint (Mentha spicata L., Lamiaceae), ginger (Zingiber officinale Rosc., Zingiberaceae), lemon (Citrus limon Burm.f., Rutaceae), grapefruit (Citrus paradisi Macf., Rutaceae), jasmine (Jasminum grandiflora L., Oleaceae), lavender (Mill., Lamiaceae), chamomile (Matricaria chamomilla L., Compositae), thyme (Thymus vulgaris L., Lamiaceae), rose (Rosa damascena Mill., Rosaceae) and cinnamon (Cinnamomum zeylanicum N. Lauraceae) were tested for their antibacterial activities towards Propionibacterium acnes and in vitro toxicology against three human cancer cell lines. Thyme, cinnamon and rose essential oils exhibited the best antibacterial activities towards P. acnes, with inhibition diameters of 40 +/- 1.2 mm, 33.5 +/- 1.5 mm and 16.5 +/- 0.7 mm, and minimal inhibitory concentrations of 0.016% (v/v), 0.016% (v/v) and 0.031% (v/v), respectively. Time-kill dynamic procedures showed that thyme, cinnamon, rose, and lavender essential oils exhibited the strongest bactericidal activities at a concentration of 0.25% (v/v), and P. acnes was completely killed after 5 min. The thyme essential oil exhibited the strongest cytotoxicity towards three human cancer cells. Its inhibition concentration 50% (IC(50)) values on PC-3, A549 and MCF-7 tumor cell lines were 0.010% (v/v), 0.011% (v/v) and 0.030% (v/v), respectively. The cytotoxicity of 10 essential oils on human prostate carcinoma cell (PC-3) was significantly stronger than on human lung carcinoma (A549) and human breast cancer (MCF-7) cell lines.
- Date of acceptance
- 2010
- Autoren
- Yuangang Zu
- Huimin Yu
- Lu Liang
- Yujie Fu
- Thomas Efferth
- Xia Liu
- Nan Wu
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/20657472
- DOI
- 10.3390/molecules15053200
- eISSN
- 1420-3049
- Externe Identifier
- PubMed Central ID: PMC6263286
- Ausgabe der Veröffentlichung
- 5
- Zeitschrift
- Molecules
- Schlüsselwörter
- Anti-Bacterial Agents
- Antineoplastic Agents
- Cell Line, Tumor
- Female
- Humans
- Male
- Microbial Sensitivity Tests
- Neoplasms
- Oils, Volatile
- Propionibacterium acnes
- Sprache
- eng
- Country
- Switzerland
- Paginierung
- 3200 - 3210
- PII
- 15053200
- Datum der Veröffentlichung
- 2010
- Status
- Published online
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2010
- Titel
- Activities of ten essential oils towards Propionibacterium acnes and PC-3, A-549 and MCF-7 cancer cells.
- Sub types
- Journal Article
- Research Support, Non-U.S. Gov't
- Ausgabe der Zeitschrift
- 15
Data source: PubMed
- Beziehungen:
- Property of