Therapeutic and Diagnostic Applications of Nanoparticles

Publication type:
Journal article
Metadata:
Autoren
  • Mahmoud Youns
  • Joerg D Hoheisel
  • Thomas Efferth
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000288997300007&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.2174/138945011794815257
eISSN
1873-5592
Externe Identifier
  • Clarivate Analytics Document Solution ID: 743DK
  • PubMed Identifier: 20955146
ISSN
1389-4501
Ausgabe der Veröffentlichung
3
Zeitschrift
CURRENT DRUG TARGETS
Schlüsselwörter
  • Nanotechnology
  • cancer
  • microarray
  • molecular targets
Paginierung
357 - 365
Datum der Veröffentlichung
2011
Status
Published
Titel
Therapeutic and Diagnostic Applications of Nanoparticles
Sub types
  • Review
Ausgabe der Zeitschrift
12

Data source: Web of Science (Lite)

Other metadata sources:
Autoren
  • Mahmoud Youns
  • Jorg D. Hoheisel
  • Thomas Efferth
DOI
10.2174/138945011794815257
ISSN
1389-4501
Ausgabe der Veröffentlichung
3
Zeitschrift
Current Drug Targets
Sprache
en
Paginierung
357 - 365
Datum der Veröffentlichung
2011
Status
Published
Herausgeber
Bentham Science Publishers Ltd.
Herausgeber URL
http://dx.doi.org/10.2174/138945011794815257
Datum der Datenerfassung
2015
Titel
Therapeutic and Diagnostic Applications of Nanoparticles
Ausgabe der Zeitschrift
12

Data source: Crossref

Abstract
Nanoparticles are sphere-like biocompatible materials made of inert silica, metal or crystals of a few nanometers in size. They are emerging as a novel class of therapeutics for cancer treatment. Being more selective and specific toward their targets, nanoparticles have the ability to enhance the anticancer effects and to simultaneously reduce systemic toxicity compared with conventional therapeutics. Furthermore, they offer the potential to overcome drug resistance leading to higher intracellular drug accumulation. Nowadays, nanotechnologies are applied to molecular diagnostics and incorporated in cutting-edge molecular diagnostic methods, such as DNA and protein microarray biochips. Nanotechnologies enable diagnosis at the single-cell and single-molecule levels. Recent progress in cancer nanotechnology raises exciting opportunities for specific drug delivery. The purpose of this review is to give an overview about different types of nanoparticles and to summarize the latest results regarding their diagnostic and therapeutic applications in the clinic with more focus on cancer treatment. Furthermore, we discuss opportunities, limitations, and challenges faced by therapeutic nanoparticles.
Addresses
  • Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemistry, University of Mainz, Staudinger Weg 5, Mainz, Germany.
Autoren
DOI
10.2174/138945011794815257
eISSN
1873-5592
Externe Identifier
  • PubMed Identifier: 20955146
Open access
false
ISSN
1389-4501
Ausgabe der Veröffentlichung
3
Zeitschrift
Current drug targets
Schlüsselwörter
  • Animals
  • Humans
  • Neoplasms
  • Antineoplastic Agents
  • Drug Carriers
  • Drug Delivery Systems
  • Microarray Analysis
  • Nanomedicine
  • Nanoparticles
Sprache
eng
Medium
Print
Paginierung
357 - 365
Datum der Veröffentlichung
2011
Status
Published
Datum der Datenerfassung
2010
Titel
Therapeutic and diagnostic applications of nanoparticles.
Sub types
  • Review
  • Journal Article
Ausgabe der Zeitschrift
12

Data source: Europe PubMed Central

Abstract
Nanoparticles are sphere-like biocompatible materials made of inert silica, metal or crystals of a few nanometers in size. They are emerging as a novel class of therapeutics for cancer treatment. Being more selective and specific toward their targets, nanoparticles have the ability to enhance the anticancer effects and to simultaneously reduce systemic toxicity compared with conventional therapeutics. Furthermore, they offer the potential to overcome drug resistance leading to higher intracellular drug accumulation. Nowadays, nanotechnologies are applied to molecular diagnostics and incorporated in cutting-edge molecular diagnostic methods, such as DNA and protein microarray biochips. Nanotechnologies enable diagnosis at the single-cell and single-molecule levels. Recent progress in cancer nanotechnology raises exciting opportunities for specific drug delivery. The purpose of this review is to give an overview about different types of nanoparticles and to summarize the latest results regarding their diagnostic and therapeutic applications in the clinic with more focus on cancer treatment. Furthermore, we discuss opportunities, limitations, and challenges faced by therapeutic nanoparticles.
Date of acceptance
2010
Autoren
  • Mahmoud Youns
  • Jörg D Hoheisel
  • Thomas Efferth
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/20955146
DOI
10.2174/138945011794815257
eISSN
1873-5592
Ausgabe der Veröffentlichung
3
Zeitschrift
Curr Drug Targets
Schlüsselwörter
  • Animals
  • Antineoplastic Agents
  • Drug Carriers
  • Drug Delivery Systems
  • Humans
  • Microarray Analysis
  • Nanomedicine
  • Nanoparticles
  • Neoplasms
Sprache
eng
Country
United Arab Emirates
Paginierung
357 - 365
PII
BSP/CDT/E-Pub/00187
Datum der Veröffentlichung
2011
Status
Published
Datum, an dem der Datensatz öffentlich gemacht wurde
2011
Titel
Therapeutic and diagnostic applications of nanoparticles.
Sub types
  • Journal Article
  • Review
Ausgabe der Zeitschrift
12

Data source: PubMed

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