Traditional Chinese medicine research in the post-genomic era: Good practice, priorities, challenges and opportunities

Publication type:
Journal article
Metadata:
Autoren
  • Halil Uzuner
  • Rudolf Bauer
  • Tai-Ping Fan
  • De-An Guo
  • Alberto Dias
  • Hani El-Nezami
  • Thomas Efferth
  • Elizabeth M Williamson
  • Michael Heinrich
  • Nicola Robinson
  • Peter J Hylands
  • Bruce M Hendry
  • Yung-Chi Cheng
  • Qihe Xu
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000302844100002&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.1016/j.jep.2012.02.028
eISSN
1872-7573
Externe Identifier
  • Clarivate Analytics Document Solution ID: 926PU
  • PubMed Identifier: 22387462
ISSN
0378-8741
Ausgabe der Veröffentlichung
3
Zeitschrift
JOURNAL OF ETHNOPHARMACOLOGY
Schlüsselwörter
  • GP-TCM
  • Traditional Chinese medicine
  • Chinese herbal medicine
  • Acupuncture
  • Omics
  • Guidelines
Paginierung
458 - 468
Datum der Veröffentlichung
2012
Status
Published
Titel
Traditional Chinese medicine research in the post-genomic era: Good practice, priorities, challenges and opportunities
Sub types
  • Editorial Material
Ausgabe der Zeitschrift
140

Data source: Web of Science (Lite)

Other metadata sources:
Autoren
  • Halil Uzuner
  • Rudolf Bauer
  • Tai-Ping Fan
  • De-an Guo
  • Alberto Dias
  • Hani El-Nezami
  • Thomas Efferth
  • Elizabeth M Williamson
  • Michael Heinrich
  • Nicola Robinson
  • Peter J Hylands
  • Bruce M Hendry
  • Yung-Chi Cheng
  • Qihe Xu
DOI
10.1016/j.jep.2012.02.028
ISSN
0378-8741
Ausgabe der Veröffentlichung
3
Zeitschrift
Journal of Ethnopharmacology
Sprache
en
Paginierung
458 - 468
Datum der Veröffentlichung
2012
Status
Published
Herausgeber
Elsevier BV
Herausgeber URL
http://dx.doi.org/10.1016/j.jep.2012.02.028
Datum der Datenerfassung
2018
Titel
Traditional Chinese medicine research in the post-genomic era: Good practice, priorities, challenges and opportunities
Ausgabe der Zeitschrift
140

Data source: Crossref

Abstract
<h4>Background and aims</h4>GP-TCM is the 1st EU-funded Coordination Action consortium dedicated to traditional Chinese medicine (TCM) research. This paper aims to summarise the objectives, structure and activities of the consortium and introduces the position of the consortium regarding good practice, priorities, challenges and opportunities in TCM research. Serving as the introductory paper for the GP-TCM Journal of Ethnopharmacology special issue, this paper describes the roadmap of this special issue and reports how the main outputs of the ten GP-TCM work packages are integrated, and have led to consortium-wide conclusions.<h4>Materials and methods</h4>Literature studies, opinion polls and discussions among consortium members and stakeholders.<h4>Results</h4>By January 2012, through 3 years of team building, the GP-TCM consortium had grown into a large collaborative network involving ∼200 scientists from 24 countries and 107 institutions. Consortium members had worked closely to address good practice issues related to various aspects of Chinese herbal medicine (CHM) and acupuncture research, the focus of this Journal of Ethnopharmacology special issue, leading to state-of-the-art reports, guidelines and consensus on the application of omics technologies in TCM research. In addition, through an online survey open to GP-TCM members and non-members, we polled opinions on grand priorities, challenges and opportunities in TCM research. Based on the poll, although consortium members and non-members had diverse opinions on the major challenges in the field, both groups agreed that high-quality efficacy/effectiveness and mechanistic studies are grand priorities and that the TCM legacy in general and its management of chronic diseases in particular represent grand opportunities. Consortium members cast their votes of confidence in omics and systems biology approaches to TCM research and believed that quality and pharmacovigilance of TCM products are not only grand priorities, but also grand challenges. Non-members, however, gave priority to integrative medicine, concerned on the impact of regulation of TCM practitioners and emphasised intersectoral collaborations in funding TCM research, especially clinical trials.<h4>Conclusions</h4>The GP-TCM consortium made great efforts to address some fundamental issues in TCM research, including developing guidelines, as well as identifying priorities, challenges and opportunities. These consortium guidelines and consensus will need dissemination, validation and further development through continued interregional, interdisciplinary and intersectoral collaborations. To promote this, a new consortium, known as the GP-TCM Research Association, is being established to succeed the 3-year fixed term FP7 GP-TCM consortium and will be officially launched at the Final GP-TCM Congress in Leiden, the Netherlands, in April 2012.
Addresses
  • King's College London, Department of Renal Medicine, London, UK. halil.uzuner@kcl.ac.uk
Autoren
  • Halil Uzuner
  • Rudolf Bauer
  • Tai-Ping Fan
  • De-An Guo
  • Alberto Dias
  • Hani El-Nezami
  • Thomas Efferth
  • Thomas Efferth
  • Elizabeth M Williamson
  • Michael Heinrich
  • Nicola Robinson
  • Peter J Hylands
  • Bruce M Hendry
  • Yung-Chi Cheng
  • Qihe Xu
DOI
10.1016/j.jep.2012.02.028
eISSN
1872-7573
Externe Identifier
  • PubMed Identifier: 22387462
Funding acknowledgements
  • European Commission: 223154
Open access
false
ISSN
0378-8741
Ausgabe der Veröffentlichung
3
Zeitschrift
Journal of ethnopharmacology
Schlüsselwörter
  • Humans
  • Drugs, Chinese Herbal
  • Acupuncture Therapy
  • Medicine, Chinese Traditional
  • Phytotherapy
  • Cooperative Behavior
  • Systems Biology
  • Genomics
  • Evidence-Based Medicine
  • Biomedical Research
  • European Union
  • Guidelines as Topic
  • Integrative Medicine
  • Pharmacovigilance
Sprache
eng
Medium
Print-Electronic
Online publication date
2012
Paginierung
458 - 468
Datum der Veröffentlichung
2012
Status
Published
Publisher licence
CC BY-NC-ND
Datum der Datenerfassung
2012
Titel
Traditional Chinese medicine research in the post-genomic era: good practice, priorities, challenges and opportunities.
Sub types
  • Research Support, Non-U.S. Gov't
  • Journal Article
Ausgabe der Zeitschrift
140

Data source: Europe PubMed Central

Abstract
BACKGROUND AND AIMS: GP-TCM is the 1st EU-funded Coordination Action consortium dedicated to traditional Chinese medicine (TCM) research. This paper aims to summarise the objectives, structure and activities of the consortium and introduces the position of the consortium regarding good practice, priorities, challenges and opportunities in TCM research. Serving as the introductory paper for the GP-TCM Journal of Ethnopharmacology special issue, this paper describes the roadmap of this special issue and reports how the main outputs of the ten GP-TCM work packages are integrated, and have led to consortium-wide conclusions. MATERIALS AND METHODS: Literature studies, opinion polls and discussions among consortium members and stakeholders. RESULTS: By January 2012, through 3 years of team building, the GP-TCM consortium had grown into a large collaborative network involving ∼200 scientists from 24 countries and 107 institutions. Consortium members had worked closely to address good practice issues related to various aspects of Chinese herbal medicine (CHM) and acupuncture research, the focus of this Journal of Ethnopharmacology special issue, leading to state-of-the-art reports, guidelines and consensus on the application of omics technologies in TCM research. In addition, through an online survey open to GP-TCM members and non-members, we polled opinions on grand priorities, challenges and opportunities in TCM research. Based on the poll, although consortium members and non-members had diverse opinions on the major challenges in the field, both groups agreed that high-quality efficacy/effectiveness and mechanistic studies are grand priorities and that the TCM legacy in general and its management of chronic diseases in particular represent grand opportunities. Consortium members cast their votes of confidence in omics and systems biology approaches to TCM research and believed that quality and pharmacovigilance of TCM products are not only grand priorities, but also grand challenges. Non-members, however, gave priority to integrative medicine, concerned on the impact of regulation of TCM practitioners and emphasised intersectoral collaborations in funding TCM research, especially clinical trials. CONCLUSIONS: The GP-TCM consortium made great efforts to address some fundamental issues in TCM research, including developing guidelines, as well as identifying priorities, challenges and opportunities. These consortium guidelines and consensus will need dissemination, validation and further development through continued interregional, interdisciplinary and intersectoral collaborations. To promote this, a new consortium, known as the GP-TCM Research Association, is being established to succeed the 3-year fixed term FP7 GP-TCM consortium and will be officially launched at the Final GP-TCM Congress in Leiden, the Netherlands, in April 2012.
Date of acceptance
2012
Autoren
  • Halil Uzuner
  • Rudolf Bauer
  • Tai-Ping Fan
  • De-An Guo
  • Alberto Dias
  • Hani El-Nezami
  • Thomas Efferth
  • Elizabeth M Williamson
  • Michael Heinrich
  • Nicola Robinson
  • Peter J Hylands
  • Bruce M Hendry
  • Yung-Chi Cheng
  • Qihe Xu
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/22387462
DOI
10.1016/j.jep.2012.02.028
eISSN
1872-7573
Ausgabe der Veröffentlichung
3
Zeitschrift
J Ethnopharmacol
Schlüsselwörter
  • Acupuncture Therapy
  • Biomedical Research
  • Cooperative Behavior
  • Drugs, Chinese Herbal
  • European Union
  • Evidence-Based Medicine
  • Genomics
  • Guidelines as Topic
  • Humans
  • Integrative Medicine
  • Medicine, Chinese Traditional
  • Pharmacovigilance
  • Phytotherapy
  • Systems Biology
Sprache
eng
Country
Ireland
Paginierung
458 - 468
PII
S0378-8741(12)00111-0
Datum der Veröffentlichung
2012
Status
Published
Datum, an dem der Datensatz öffentlich gemacht wurde
2012
Titel
Traditional Chinese medicine research in the post-genomic era: good practice, priorities, challenges and opportunities.
Sub types
  • Journal Article
  • Research Support, Non-U.S. Gov't
Ausgabe der Zeitschrift
140

Data source: PubMed

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