Stem Cells, Cancer Stem-Like Cells, and Natural Products
- Publication type:
- Journal article
- Metadata:
-
- Autoren
- Thomas Efferth
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000306105700002&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1055/s-0031-1298540
- eISSN
- 1439-0221
- Externe Identifier
- Clarivate Analytics Document Solution ID: 970CM
- PubMed Identifier: 22573366
- ISSN
- 0032-0943
- Ausgabe der Veröffentlichung
- 10
- Zeitschrift
- PLANTA MEDICA
- Schlüsselwörter
- general methods
- cancer
- Paginierung
- 935 - 942
- Datum der Veröffentlichung
- 2012
- Status
- Published
- Titel
- Stem Cells, Cancer Stem-Like Cells, and Natural Products
- Sub types
- Review
- Ausgabe der Zeitschrift
- 78
Data source: Web of Science (Lite)
- Other metadata sources:
-
- Autoren
- Thomas Efferth
- DOI
- 10.1055/s-0031-1298540
- eISSN
- 1439-0221
- ISSN
- 0032-0943
- Ausgabe der Veröffentlichung
- 10
- Zeitschrift
- Planta Medica
- Sprache
- en
- Online publication date
- 2012
- Paginierung
- 935 - 942
- Datum der Veröffentlichung
- 2012
- Status
- Published
- Herausgeber
- Georg Thieme Verlag KG
- Herausgeber URL
- http://dx.doi.org/10.1055/s-0031-1298540
- Datum der Datenerfassung
- 2017
- Titel
- Stem Cells, Cancer Stem-Like Cells, and Natural Products
- Ausgabe der Zeitschrift
- 78
Data source: Crossref
- Abstract
- Somatic stem cells can be found in many rapidly regenerating tissues, e.g., the skin, gastrointestinal mucosa, and hematopoietic system, but are also present at low numbers in non-regenerative organs such as the heart and brain. In these organs, somatic stem cells aid in normal tissue homeostasis and repair after injury as well as self-renewal and the generation of specific progenitor cells during differentiation. Cancer stem-like cells are a small subpopulation of self-renewing cells that are able to proliferate upon appropriate stimulation and differentiate into heterogeneous lineages in tumors. Modulation of the behavior of normal tissue stem cells and cancer stem-like cells is an emerging and thriving new field of research. The present review gives an overview of the state-of-the-art findings and highlights perspectives for future scientific developments and clinical application.
- Addresses
- Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemistry, Johannes Gutenberg University, Mainz, Germany. efferth@uni-mainz.de
- Autoren
- Thomas Efferth
- Thomas Efferth
- DOI
- 10.1055/s-0031-1298540
- eISSN
- 1439-0221
- Externe Identifier
- PubMed Identifier: 22573366
- Open access
- false
- ISSN
- 0032-0943
- Ausgabe der Veröffentlichung
- 10
- Zeitschrift
- Planta medica
- Schlüsselwörter
- Pluripotent Stem Cells
- Humans
- Neoplasms
- Tretinoin
- Antineoplastic Agents, Phytogenic
- Biological Products
- Signal Transduction
- Cell Differentiation
- Cell Proliferation
- Cell Survival
- Cell Lineage
- Embryonic Stem Cells
- Neoplastic Stem Cells
- Cell Cycle Checkpoints
- Sprache
- eng
- Medium
- Print-Electronic
- Online publication date
- 2012
- Paginierung
- 935 - 942
- Datum der Veröffentlichung
- 2012
- Status
- Published
- Datum der Datenerfassung
- 2012
- Titel
- Stem cells, cancer stem-like cells, and natural products.
- Sub types
- Review
- Journal Article
- Ausgabe der Zeitschrift
- 78
Data source: Europe PubMed Central
- Abstract
- Somatic stem cells can be found in many rapidly regenerating tissues, e.g., the skin, gastrointestinal mucosa, and hematopoietic system, but are also present at low numbers in non-regenerative organs such as the heart and brain. In these organs, somatic stem cells aid in normal tissue homeostasis and repair after injury as well as self-renewal and the generation of specific progenitor cells during differentiation. Cancer stem-like cells are a small subpopulation of self-renewing cells that are able to proliferate upon appropriate stimulation and differentiate into heterogeneous lineages in tumors. Modulation of the behavior of normal tissue stem cells and cancer stem-like cells is an emerging and thriving new field of research. The present review gives an overview of the state-of-the-art findings and highlights perspectives for future scientific developments and clinical application.
- Autoren
- Thomas Efferth
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/22573366
- DOI
- 10.1055/s-0031-1298540
- eISSN
- 1439-0221
- Ausgabe der Veröffentlichung
- 10
- Zeitschrift
- Planta Med
- Schlüsselwörter
- Antineoplastic Agents, Phytogenic
- Biological Products
- Cell Cycle Checkpoints
- Cell Differentiation
- Cell Lineage
- Cell Proliferation
- Cell Survival
- Embryonic Stem Cells
- Humans
- Neoplasms
- Neoplastic Stem Cells
- Pluripotent Stem Cells
- Signal Transduction
- Tretinoin
- Sprache
- eng
- Country
- Germany
- Paginierung
- 935 - 942
- Datum der Veröffentlichung
- 2012
- Status
- Published
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2012
- Titel
- Stem cells, cancer stem-like cells, and natural products.
- Sub types
- Journal Article
- Review
- Ausgabe der Zeitschrift
- 78
Data source: PubMed
- Beziehungen:
- Property of