Unprecedented new nonadecyl para-hydroperoxycinnamate isolated from Erythrina excelsa and its cytotoxic activity
- Publication type:
- Journal article
- Metadata:
-
- Autoren
- Guy MN Kwamou
- Louis P Sandjo
- Victor Kuete
- Anaelle AK Wandja
- Simplice B Tankeo
- Thomas Efferth
- Augustin E Nkengfack
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000353422200006&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1080/14786419.2014.959519
- eISSN
- 1478-6427
- Externe Identifier
- Clarivate Analytics Document Solution ID: CG6OT
- PubMed Identifier: 25220189
- ISSN
- 1478-6419
- Ausgabe der Veröffentlichung
- 10
- Zeitschrift
- NATURAL PRODUCT RESEARCH
- Schlüsselwörter
- para-hydroperoxycinnamate
- drug resistance
- Fabaceae
- anticancer activity
- Paginierung
- 921 - 925
- Datum der Veröffentlichung
- 2015
- Status
- Published
- Titel
- Unprecedented new nonadecyl <i>para</i>-hydroperoxycinnamate isolated from <i>Erythrina excelsa</i> and its cytotoxic activity
- Sub types
- Article
- Ausgabe der Zeitschrift
- 29
Data source: Web of Science (Lite)
- Other metadata sources:
-
- Autoren
- Guy MN Kwamou
- Louis P Sandjo
- Victor Kuete
- Anaelle AK Wandja
- Simplice B Tankeo
- Thomas Efferth
- Augustin E Nkengfack
- DOI
- 10.1080/14786419.2014.959519
- eISSN
- 1478-6427
- ISSN
- 1478-6419
- Ausgabe der Veröffentlichung
- 10
- Zeitschrift
- Natural Product Research
- Sprache
- en
- Online publication date
- 2014
- Paginierung
- 921 - 925
- Datum der Veröffentlichung
- 2015
- Status
- Published
- Herausgeber
- Informa UK Limited
- Herausgeber URL
- http://dx.doi.org/10.1080/14786419.2014.959519
- Datum der Datenerfassung
- 2016
- Titel
- Unprecedented new nonadecyl<i>para</i>-hydroperoxycinnamate isolated from<i>Erythrina excelsa</i>and its cytotoxic activity
- Ausgabe der Zeitschrift
- 29
Data source: Crossref
- Abstract
- A new unprecedented cinnamate derivative (1) was obtained from Erythrina excelsa (Leguminosae) and identified as nonadecyl para-hydroperoxycinnamate. This compound was isolated together with three known compounds, namely lupeol (2), mixture of sitosterol and stigmasterol (3), and isoneorautenol (4). Their structures were established on the basis of NMR and mass spectroscopic data in conjunction with those reported in the literature. Compound 1 was evaluated for its capability of inhibiting cancer cell lines and growth of a panel of microbial strains. It turned out that 1 is moderately to significantly cytotoxic against six cancer cell lines and shows weak to no antimicrobial activity.
- Addresses
- a Department of Organic Chemistry , University of Yaoundé I , P.O. Box 812, Yaoundé , Cameroon.
- Autoren
- Guy MN Kwamou
- Louis P Sandjo
- Victor Kuete
- Anaelle AK Wandja
- Simplice B Tankeo
- Thomas Efferth
- Thomas Efferth
- Augustin E Nkengfack
- DOI
- 10.1080/14786419.2014.959519
- eISSN
- 1478-6427
- Externe Identifier
- PubMed Identifier: 25220189
- Open access
- false
- ISSN
- 1478-6419
- Ausgabe der Veröffentlichung
- 10
- Zeitschrift
- Natural product research
- Schlüsselwörter
- Cell Line, Tumor
- Humans
- Erythrina
- Plant Bark
- Cinnamates
- Plant Extracts
- Antineoplastic Agents, Phytogenic
- Anti-Bacterial Agents
- Magnetic Resonance Spectroscopy
- Drug Screening Assays, Antitumor
- Molecular Structure
- Mass Spectrometry
- Sprache
- eng
- Medium
- Print-Electronic
- Online publication date
- 2014
- Paginierung
- 921 - 925
- Datum der Veröffentlichung
- 2015
- Status
- Published
- Datum der Datenerfassung
- 2014
- Titel
- Unprecedented new nonadecyl para-hydroperoxycinnamate isolated from Erythrina excelsa and its cytotoxic activity.
- Sub types
- Research Support, Non-U.S. Gov't
- Journal Article
- Ausgabe der Zeitschrift
- 29
Data source: Europe PubMed Central
- Abstract
- A new unprecedented cinnamate derivative (1) was obtained from Erythrina excelsa (Leguminosae) and identified as nonadecyl para-hydroperoxycinnamate. This compound was isolated together with three known compounds, namely lupeol (2), mixture of sitosterol and stigmasterol (3), and isoneorautenol (4). Their structures were established on the basis of NMR and mass spectroscopic data in conjunction with those reported in the literature. Compound 1 was evaluated for its capability of inhibiting cancer cell lines and growth of a panel of microbial strains. It turned out that 1 is moderately to significantly cytotoxic against six cancer cell lines and shows weak to no antimicrobial activity.
- Autoren
- Guy MN Kwamou
- Louis P Sandjo
- Victor Kuete
- Anaelle AK Wandja
- Simplice B Tankeo
- Thomas Efferth
- Augustin E Nkengfack
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/25220189
- DOI
- 10.1080/14786419.2014.959519
- eISSN
- 1478-6427
- Ausgabe der Veröffentlichung
- 10
- Zeitschrift
- Nat Prod Res
- Schlüsselwörter
- Fabaceae
- anticancer activity
- drug resistance
- para-hydroperoxycinnamate
- Anti-Bacterial Agents
- Antineoplastic Agents, Phytogenic
- Cell Line, Tumor
- Cinnamates
- Drug Screening Assays, Antitumor
- Erythrina
- Humans
- Magnetic Resonance Spectroscopy
- Mass Spectrometry
- Molecular Structure
- Plant Bark
- Plant Extracts
- Sprache
- eng
- Country
- England
- Paginierung
- 921 - 925
- Datum der Veröffentlichung
- 2015
- Status
- Published
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2015
- Titel
- Unprecedented new nonadecyl para-hydroperoxycinnamate isolated from Erythrina excelsa and its cytotoxic activity.
- Sub types
- Journal Article
- Research Support, Non-U.S. Gov't
- Ausgabe der Zeitschrift
- 29
Data source: PubMed
- Beziehungen:
- Property of