Application of integrative cloud point extraction and concentration for the analysis of polyphenols and alkaloids in mulberry leaves

Publication type:
Journal article
Metadata:
Autoren
  • Na Guo
  • Yi-Wei Jiang
  • Ping Kou
  • Zhi-Ming Liu
  • Thomas Efferth
  • Yan-Yan Li
  • Yu-Jie Fu
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000462805600016&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.1016/j.jpba.2019.02.002
eISSN
1873-264X
Externe Identifier
  • Clarivate Analytics Document Solution ID: HR0GF
  • PubMed Identifier: 30771646
ISSN
0731-7085
Zeitschrift
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Schlüsselwörter
  • Mulberry leaves
  • Ultrasound-assisted cloud-point extraction
  • Triton X-114
  • Polyphenols
  • Alkaloids
Paginierung
132 - 139
Datum der Veröffentlichung
2019
Status
Published
Titel
Application of integrative cloud point extraction and concentration for the analysis of polyphenols and alkaloids in mulberry leaves
Sub types
  • Article
Ausgabe der Zeitschrift
167

Data source: Web of Science (Lite)

Other metadata sources:
Autoren
  • Na Guo
  • Yi-Wei Jiang
  • Ping Kou
  • Zhi-Ming Liu
  • Thomas Efferth
  • Yan-Yan Li
  • Yu-Jie Fu
DOI
10.1016/j.jpba.2019.02.002
ISSN
0731-7085
Zeitschrift
Journal of Pharmaceutical and Biomedical Analysis
Sprache
en
Paginierung
132 - 139
Datum der Veröffentlichung
2019
Status
Published
Herausgeber
Elsevier BV
Herausgeber URL
http://dx.doi.org/10.1016/j.jpba.2019.02.002
Datum der Datenerfassung
2020
Titel
Application of integrative cloud point extraction and concentration for the analysis of polyphenols and alkaloids in mulberry leaves
Ausgabe der Zeitschrift
167

Data source: Crossref

Abstract
A simple and efficient method based on cloud point extraction and concentration combined with high performance liquid chromatography was developed for the simultaneous separation and determination of five target compounds (deoxynojirimycin, chlorogenic acid, rutin, isoquercitrin and astragalin) in mulberry leaves samples. Firstly, to obtain a high extraction rate, the ultrasound assisted extraction was developed on acid modified Triton X-114 system. Under the optimal conditions, the total maximum extraction yields of five target compounds reached 20.80 mg/g, which was superior to conventional solvent extraction. After the cloud point extraction and concentration, the HPLC analysis parameters of calibration curve, intra-day and inter-day precision, limits of detection for the five target compounds were determined systematically. The proposed method was successfully used to extract, concentrate, separate and determine the polyphenols and alkaloids in mulberry leaves.
Addresses
  • Northeast Forestry University, Hexing Road 26, 150040, Harbin, PR China.
Autoren
  • Na Guo
  • Yi-Wei Jiang
  • Ping Kou
  • Zhi-Ming Liu
  • Thomas Efferth
  • Yan-Yan Li
  • Yu-Jie Fu
DOI
10.1016/j.jpba.2019.02.002
eISSN
1873-264X
Externe Identifier
  • PubMed Identifier: 30771646
Funding acknowledgements
  • Fundamental Research Funds for the Central Universities: 2572017ET03
  • Fundamental Research Funds for the Central Universities: 2572018AB12
  • Fundamental Research Funds for the Central Universities: 2572017EA03
  • National Key R&D Program of China: 2016YFD0600805
Open access
false
ISSN
0731-7085
Zeitschrift
Journal of pharmaceutical and biomedical analysis
Schlüsselwörter
  • Morus
  • Plant Leaves
  • Alkaloids
  • Solvents
  • Surface-Active Agents
  • Chromatography, High Pressure Liquid
  • Polyphenols
  • Liquid-Liquid Extraction
  • Ultrasonic Waves
Sprache
eng
Medium
Print-Electronic
Online publication date
2019
Paginierung
132 - 139
Datum der Veröffentlichung
2019
Status
Published
Datum der Datenerfassung
2019
Titel
Application of integrative cloud point extraction and concentration for the analysis of polyphenols and alkaloids in mulberry leaves.
Sub types
  • Journal Article
Ausgabe der Zeitschrift
167

Data source: Europe PubMed Central

Abstract
A simple and efficient method based on cloud point extraction and concentration combined with high performance liquid chromatography was developed for the simultaneous separation and determination of five target compounds (deoxynojirimycin, chlorogenic acid, rutin, isoquercitrin and astragalin) in mulberry leaves samples. Firstly, to obtain a high extraction rate, the ultrasound assisted extraction was developed on acid modified Triton X-114 system. Under the optimal conditions, the total maximum extraction yields of five target compounds reached 20.80 mg/g, which was superior to conventional solvent extraction. After the cloud point extraction and concentration, the HPLC analysis parameters of calibration curve, intra-day and inter-day precision, limits of detection for the five target compounds were determined systematically. The proposed method was successfully used to extract, concentrate, separate and determine the polyphenols and alkaloids in mulberry leaves.
Date of acceptance
2019
Autoren
  • Na Guo
  • Yi-Wei Jiang
  • Ping Kou
  • Zhi-Ming Liu
  • Thomas Efferth
  • Yan-Yan Li
  • Yu-Jie Fu
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/30771646
DOI
10.1016/j.jpba.2019.02.002
eISSN
1873-264X
Zeitschrift
J Pharm Biomed Anal
Schlüsselwörter
  • Alkaloids
  • Mulberry leaves
  • Polyphenols
  • Triton X-114
  • Ultrasound-assisted cloud-point extraction
  • Alkaloids
  • Chromatography, High Pressure Liquid
  • Liquid-Liquid Extraction
  • Morus
  • Plant Leaves
  • Polyphenols
  • Solvents
  • Surface-Active Agents
  • Ultrasonic Waves
Sprache
eng
Country
England
Paginierung
132 - 139
PII
S0731-7085(18)32539-1
Datum der Veröffentlichung
2019
Status
Published
Datum, an dem der Datensatz öffentlich gemacht wurde
2019
Titel
Application of integrative cloud point extraction and concentration for the analysis of polyphenols and alkaloids in mulberry leaves.
Sub types
  • Journal Article
Ausgabe der Zeitschrift
167

Data source: PubMed

Beziehungen:
Property of

Tools