Anti-poliovirus activity of Nerium oleander aqueous extract
- Publication type:
- Journal article
- Metadata:
-
- Autoren
- Giuseppina Sanna
- Silvia Madeddu
- Alessandra Serra
- David Collu
- Thomas Efferth
- F Lukmanul Hakkim
- Luay Rashan
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000613796200014&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1080/14786419.2019.1582046
- eISSN
- 1478-6427
- Externe Identifier
- Clarivate Analytics Document Solution ID: QA9WW
- PubMed Identifier: 30908090
- ISSN
- 1478-6419
- Ausgabe der Veröffentlichung
- 4
- Zeitschrift
- NATURAL PRODUCT RESEARCH
- Schlüsselwörter
- Apocynaceae
- Nerium oleander
- hot extract
- cold extract
- poliovirus
- antiviral activity
- Paginierung
- 633 - 636
- Datum der Veröffentlichung
- 2021
- Status
- Published
- Titel
- Anti-poliovirus activity of <i>Nerium oleander</i> aqueous extract
- Sub types
- Article
- Ausgabe der Zeitschrift
- 35
Data source: Web of Science (Lite)
- Other metadata sources:
-
- Autoren
- Giuseppina Sanna
- Silvia Madeddu
- Alessandra Serra
- David Collu
- Thomas Efferth
- F Lukmanul Hakkim
- Luay Rashan
- DOI
- 10.1080/14786419.2019.1582046
- eISSN
- 1478-6427
- ISSN
- 1478-6419
- Ausgabe der Veröffentlichung
- 4
- Zeitschrift
- Natural Product Research
- Sprache
- en
- Online publication date
- 2019
- Paginierung
- 633 - 636
- Datum der Veröffentlichung
- 2021
- Status
- Published
- Herausgeber
- Informa UK Limited
- Herausgeber URL
- http://dx.doi.org/10.1080/14786419.2019.1582046
- Datum der Datenerfassung
- 2021
- Titel
- Anti-poliovirus activity of <i>Nerium oleander</i> aqueous extract
- Ausgabe der Zeitschrift
- 35
Data source: Crossref
- Abstract
- <i>Nerium oleander</i> (NO), a member of the Apocynaceae family, is an ornamental plant. In this study, we evaluated the antiviral activity of hot and cold extract of NO against six different viruses such as herpes simplex virus type 1 (HSV-1), polio virus type 1 (Sb-1), vesicular stomatitis virus (VSV), reovirus type-1 (Reo-1), human immunodeficiency virus type-1 (HIV-1), and yellow fever virus (YFV). Interestingly the results of plaque reduction assay demonstrated that both, hot extract and cold extract (breastin) of NO inhibited Sb-1 viral infection.In order to identify the mechanism by which NO exerts its antiviral activity, the virucidal effect, the time of addition and the adsorption assay were carried out. Results demonstrated that NO exerts its effect after infection period, particularly during the first two hours post infection.
- Addresses
- Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, Italy.
- Autoren
- Giuseppina Sanna
- Silvia Madeddu
- Alessandra Serra
- David Collu
- Thomas Efferth
- F Lukmanul Hakkim
- Luay Rashan
- DOI
- 10.1080/14786419.2019.1582046
- eISSN
- 1478-6427
- Externe Identifier
- PubMed Identifier: 30908090
- Open access
- false
- ISSN
- 1478-6419
- Ausgabe der Veröffentlichung
- 4
- Zeitschrift
- Natural product research
- Schlüsselwörter
- Vero Cells
- Animals
- Poliovirus
- Nerium
- Plant Extracts
- Antiviral Agents
- Cell Death
- Kinetics
- Chlorocebus aethiops
- Sprache
- eng
- Medium
- Print-Electronic
- Online publication date
- 2019
- Paginierung
- 633 - 636
- Datum der Veröffentlichung
- 2021
- Status
- Published
- Datum der Datenerfassung
- 2019
- Titel
- Anti-poliovirus activity of <i>Nerium oleander</i> aqueous extract.
- Sub types
- Journal Article
- Ausgabe der Zeitschrift
- 35
Data source: Europe PubMed Central
- Abstract
- Nerium oleander (NO), a member of the Apocynaceae family, is an ornamental plant. In this study, we evaluated the antiviral activity of hot and cold extract of NO against six different viruses such as herpes simplex virus type 1 (HSV-1), polio virus type 1 (Sb-1), vesicular stomatitis virus (VSV), reovirus type-1 (Reo-1), human immunodeficiency virus type-1 (HIV-1), and yellow fever virus (YFV). Interestingly the results of plaque reduction assay demonstrated that both, hot extract and cold extract (breastin) of NO inhibited Sb-1 viral infection.In order to identify the mechanism by which NO exerts its antiviral activity, the virucidal effect, the time of addition and the adsorption assay were carried out. Results demonstrated that NO exerts its effect after infection period, particularly during the first two hours post infection.
- Autoren
- Giuseppina Sanna
- Silvia Madeddu
- Alessandra Serra
- David Collu
- Thomas Efferth
- F Lukmanul Hakkim
- Luay Rashan
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/30908090
- DOI
- 10.1080/14786419.2019.1582046
- eISSN
- 1478-6427
- Ausgabe der Veröffentlichung
- 4
- Zeitschrift
- Nat Prod Res
- Schlüsselwörter
- Apocynaceae
- Nerium oleander
- antiviral activity
- cold extract
- hot extract
- poliovirus
- Animals
- Antiviral Agents
- Cell Death
- Chlorocebus aethiops
- Kinetics
- Nerium
- Plant Extracts
- Poliovirus
- Vero Cells
- Sprache
- eng
- Country
- England
- Paginierung
- 633 - 636
- Datum der Veröffentlichung
- 2021
- Status
- Published
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2021
- Titel
- Anti-poliovirus activity of Nerium oleander aqueous extract.
- Sub types
- Journal Article
- Ausgabe der Zeitschrift
- 35
Data source: PubMed
- Beziehungen:
- Property of