The pharmacology of the genus Sophora (Fabaceae): An updated review
- Publication type:
- Journal article
- Metadata:
-
- Autoren
- Shaza H Aly
- Ahmed M Elissawy
- Omayma A Eldahshan
- Mohamed A Elshanawany
- Thomas Efferth
- Abdel Nasser B Singab
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000499700400021&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1016/j.phymed.2019.153070
- eISSN
- 1618-095X
- Externe Identifier
- Clarivate Analytics Document Solution ID: JR5YO
- PubMed Identifier: 31514082
- ISSN
- 0944-7113
- Zeitschrift
- PHYTOMEDICINE
- Schlüsselwörter
- Sophora, Biological activity
- Molecular pharmacology
- Fabaceae
- Signaling pathways
- Artikelnummer
- ARTN 153070
- Datum der Veröffentlichung
- 2019
- Status
- Published
- Titel
- The pharmacology of the genus Sophora (Fabaceae): An updated review
- Sub types
- Review
- Ausgabe der Zeitschrift
- 64
Data source: Web of Science (Lite)
- Other metadata sources:
-
- Autoren
- Shaza H Aly
- Ahmed M Elissawy
- Omayma A Eldahshan
- Mohamed A Elshanawany
- Thomas Efferth
- Abdel Nasser B Singab
- DOI
- 10.1016/j.phymed.2019.153070
- ISSN
- 0944-7113
- Zeitschrift
- Phytomedicine
- Sprache
- en
- Artikelnummer
- 153070
- Paginierung
- 153070 - 153070
- Datum der Veröffentlichung
- 2019
- Status
- Published
- Herausgeber
- Elsevier BV
- Herausgeber URL
- http://dx.doi.org/10.1016/j.phymed.2019.153070
- Datum der Datenerfassung
- 2020
- Titel
- The pharmacology of the genus Sophora (Fabaceae): An updated review
- Ausgabe der Zeitschrift
- 64
Data source: Crossref
- Abstract
- <h4>Background</h4>The genus Sophora (Fabaceae) represents one of the important medicinal plant genera regarding its chemical constituents and outstanding pharmacological activities.<h4>Purpose</h4>In this review, we surveyed the latest findings on the bioactivities of different Sophora extracts and isolated phytochemicals during the past 8 years (2011-2019) updating the latest review article in 2011. The aim of this review is to focus on the molecular pharmacology of Sophora species to provide the rationale basis for the development of novel drugs.<h4>Results</h4>Sophora and its bioactive compounds possess outstanding pharmacological properties, especially as anticancer and anti-inflammatory drugs, in addition to its antioxidant, antibacterial, antifungal and antiviral properties.<h4>Conclusion</h4>Based on their use in traditional medicine, Sophora species exert a plethora of cellular and molecular activities, which render them as attractive candidates for rationale drug development. Randomized, placebo-controlled clinical trials are required for further integration of Sophora-based phototherapies into conventional medicine.
- Addresses
- Department of Pharmacognosy, Faculty of Pharmacy, Badr University, Cairo, Egypt.
- Autoren
- Shaza H Aly
- Ahmed M Elissawy
- Omayma A Eldahshan
- Mohamed A Elshanawany
- Thomas Efferth
- Abdel Nasser B Singab
- DOI
- 10.1016/j.phymed.2019.153070
- eISSN
- 1618-095X
- Externe Identifier
- PubMed Identifier: 31514082
- Open access
- false
- ISSN
- 0944-7113
- Zeitschrift
- Phytomedicine : international journal of phytotherapy and phytopharmacology
- Schlüsselwörter
- Animals
- Humans
- Sophora
- Plants, Medicinal
- Anti-Inflammatory Agents
- Plant Extracts
- Antineoplastic Agents, Phytogenic
- Antioxidants
- Anti-Infective Agents
- Medicine, Traditional
- Ethnopharmacology
- Phytochemicals
- Sprache
- eng
- Medium
- Print-Electronic
- Online publication date
- 2019
- Paginierung
- 153070
- Datum der Veröffentlichung
- 2019
- Status
- Published
- Datum der Datenerfassung
- 2019
- Titel
- The pharmacology of the genus Sophora (Fabaceae): An updated review.
- Sub types
- Review
- Journal Article
- Ausgabe der Zeitschrift
- 64
Data source: Europe PubMed Central
- Abstract
- BACKGROUND: The genus Sophora (Fabaceae) represents one of the important medicinal plant genera regarding its chemical constituents and outstanding pharmacological activities. PURPOSE: In this review, we surveyed the latest findings on the bioactivities of different Sophora extracts and isolated phytochemicals during the past 8 years (2011-2019) updating the latest review article in 2011. The aim of this review is to focus on the molecular pharmacology of Sophora species to provide the rationale basis for the development of novel drugs. RESULTS: Sophora and its bioactive compounds possess outstanding pharmacological properties, especially as anticancer and anti-inflammatory drugs, in addition to its antioxidant, antibacterial, antifungal and antiviral properties. CONCLUSION: Based on their use in traditional medicine, Sophora species exert a plethora of cellular and molecular activities, which render them as attractive candidates for rationale drug development. Randomized, placebo-controlled clinical trials are required for further integration of Sophora-based phototherapies into conventional medicine.
- Date of acceptance
- 2019
- Autoren
- Shaza H Aly
- Ahmed M Elissawy
- Omayma A Eldahshan
- Mohamed A Elshanawany
- Thomas Efferth
- Abdel Nasser B Singab
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/31514082
- DOI
- 10.1016/j.phymed.2019.153070
- eISSN
- 1618-095X
- Zeitschrift
- Phytomedicine
- Schlüsselwörter
- Fabaceae
- Molecular pharmacology
- Signaling pathways
- Sophora, Biological activity
- Animals
- Anti-Infective Agents
- Anti-Inflammatory Agents
- Antineoplastic Agents, Phytogenic
- Antioxidants
- Ethnopharmacology
- Humans
- Medicine, Traditional
- Phytochemicals
- Plant Extracts
- Plants, Medicinal
- Sophora
- Sprache
- eng
- Country
- Germany
- Paginierung
- 153070
- PII
- S0944-7113(19)30235-1
- Datum der Veröffentlichung
- 2019
- Status
- Published
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2020
- Titel
- The pharmacology of the genus Sophora (Fabaceae): An updated review.
- Sub types
- Journal Article
- Review
- Ausgabe der Zeitschrift
- 64
Data source: PubMed
- Beziehungen:
- Property of