Terpenoid bio-transformations and applications via cell/organ cultures: a systematic review
- Publication type:
- Journal article
- Metadata:
-
- Autoren
- Mohamed-Elamir F Hegazy
- Abdelsamed I Elshamy
- Tarik A Mohamed
- Taha A Hussien
- Soleiman E Helaly
- Nahla S Abdel-Azim
- Khaled A Shams
- Abdelaaty A Shahat
- Wafaa A Tawfik
- Alaa M Shahen
- Abdessamad Debbab
- Hesham R El Saedi
- Abou El-Hamd H Mohamed
- Faiza M Hammouda
- Mahmoud Sakr
- Paul W Pare
- Thomas Efferth
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000493237700001&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1080/07388551.2019.1681932
- eISSN
- 1549-7801
- Externe Identifier
- Clarivate Analytics Document Solution ID: OM4VJ
- PubMed Identifier: 31663377
- ISSN
- 0738-8551
- Ausgabe der Veröffentlichung
- 1
- Zeitschrift
- CRITICAL REVIEWS IN BIOTECHNOLOGY
- Schlüsselwörter
- Terpenoid
- natural metabolites
- enzymatic biotransformations
- plant cell cultures
- active natural product derivatives
- Pharmaceutical products
- Paginierung
- 64 - 82
- Datum der Veröffentlichung
- 2020
- Status
- Published
- Titel
- Terpenoid bio-transformations and applications via cell/organ cultures: a systematic review
- Sub types
- Review
- Ausgabe der Zeitschrift
- 40
Data source: Web of Science (Lite)
- Other metadata sources:
-
- Autoren
- Mohamed-Elamir F Hegazy
- Abdelsamed I Elshamy
- Tarik A Mohamed
- Taha A Hussien
- Soleiman E Helaly
- Nahla S Abdel-Azim
- Khaled A Shams
- Abdelaaty A Shahat
- Wafaa A Tawfik
- Alaa M Shahen
- Abdessamad Debbab
- Hesham R El Saedi
- Abou El-Hamd H Mohamed
- Faiza M Hammouda
- Mahmoud Sakr
- Paul W Paré
- Thomas Efferth
- DOI
- 10.1080/07388551.2019.1681932
- eISSN
- 1549-7801
- ISSN
- 0738-8551
- Ausgabe der Veröffentlichung
- 1
- Zeitschrift
- Critical Reviews in Biotechnology
- Sprache
- en
- Online publication date
- 2019
- Paginierung
- 64 - 82
- Datum der Veröffentlichung
- 2020
- Status
- Published
- Herausgeber
- Informa UK Limited
- Herausgeber URL
- http://dx.doi.org/10.1080/07388551.2019.1681932
- Datum der Datenerfassung
- 2019
- Titel
- Terpenoid bio-transformations and applications via cell/organ cultures: a systematic review
- Ausgabe der Zeitschrift
- 40
Data source: Crossref
- Abstract
- Structurally diverse natural products are valued for their targeted biological activity. The challenge of working with such metabolites is their low natural abundance and complex structure, often with multiple stereocenters, precludes large-scale or unsophisticated chemical synthesis. Since select plants contain the enzymatic machinery necessary to produce specialized compounds, tissue cultures can be used to achieve key transformations for large-scale chemical and/or pharmaceutical applications. In this context, plant tissue-culture bio-transformations have demonstrated great promise in the preparation of pharmaceutical products. This review describes the capacity of cultured plant cells to transform terpenoid natural products and the specific application of such transformations over the past three decades (1988-2019).
- Addresses
- Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemistry, Johannes Gutenberg University, Mainz, Germany.
- Autoren
- Mohamed-Elamir F Hegazy
- Abdelsamed I Elshamy
- Tarik A Mohamed
- Taha A Hussien
- Soleiman E Helaly
- Nahla S Abdel-Azim
- Khaled A Shams
- Abdelaaty A Shahat
- Wafaa A Tawfik
- Alaa M Shahen
- Abdessamad Debbab
- Hesham R El Saedi
- Abou El-Hamd H Mohamed
- Faiza M Hammouda
- Mahmoud Sakr
- Paul W Paré
- Thomas Efferth
- Thomas Efferth
- DOI
- 10.1080/07388551.2019.1681932
- eISSN
- 1549-7801
- Externe Identifier
- PubMed Identifier: 31663377
- Open access
- false
- ISSN
- 0738-8551
- Ausgabe der Veröffentlichung
- 1
- Zeitschrift
- Critical reviews in biotechnology
- Schlüsselwörter
- Plants
- Terpenes
- Cell Culture Techniques
- Biotransformation
- Plant Structures
- Sprache
- eng
- Medium
- Print-Electronic
- Online publication date
- 2019
- Paginierung
- 64 - 82
- Datum der Veröffentlichung
- 2020
- Status
- Published
- Datum der Datenerfassung
- 2019
- Titel
- Terpenoid bio-transformations and applications via cell/organ cultures: a systematic review.
- Sub types
- Systematic Review
- Journal Article
- Ausgabe der Zeitschrift
- 40
Data source: Europe PubMed Central
- Abstract
- Structurally diverse natural products are valued for their targeted biological activity. The challenge of working with such metabolites is their low natural abundance and complex structure, often with multiple stereocenters, precludes large-scale or unsophisticated chemical synthesis. Since select plants contain the enzymatic machinery necessary to produce specialized compounds, tissue cultures can be used to achieve key transformations for large-scale chemical and/or pharmaceutical applications. In this context, plant tissue-culture bio-transformations have demonstrated great promise in the preparation of pharmaceutical products. This review describes the capacity of cultured plant cells to transform terpenoid natural products and the specific application of such transformations over the past three decades (1988-2019).
- Autoren
- Mohamed-Elamir F Hegazy
- Abdelsamed I Elshamy
- Tarik A Mohamed
- Taha A Hussien
- Soleiman E Helaly
- Nahla S Abdel-Azim
- Khaled A Shams
- Abdelaaty A Shahat
- Wafaa A Tawfik
- Alaa M Shahen
- Abdessamad Debbab
- Hesham R El Saedi
- Abou El-Hamd H Mohamed
- Faiza M Hammouda
- Mahmoud Sakr
- Paul W Paré
- Thomas Efferth
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/31663377
- DOI
- 10.1080/07388551.2019.1681932
- eISSN
- 1549-7801
- Ausgabe der Veröffentlichung
- 1
- Zeitschrift
- Crit Rev Biotechnol
- Schlüsselwörter
- Pharmaceutical products
- Terpenoid
- active natural product derivatives
- enzymatic biotransformations
- natural metabolites
- plant cell cultures
- Biotransformation
- Cell Culture Techniques
- Plant Structures
- Plants
- Terpenes
- Sprache
- eng
- Country
- England
- Paginierung
- 64 - 82
- Datum der Veröffentlichung
- 2020
- Status
- Published
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2020
- Titel
- Terpenoid bio-transformations and applications via cell/organ cultures: a systematic review.
- Sub types
- Journal Article
- Systematic Review
- Ausgabe der Zeitschrift
- 40
Data source: PubMed
- Beziehungen:
- Property of