(±)-Alternarlactones A and B, Two Antiparasitic Alternariol-like Dimers from the Fungus Alternaria alternata P1210 Isolated from the Halophyte Salicornia sp.

Publication type:
Journal article
Metadata:
Autoren
  • Yan-Ni Shi
  • Stefan Pusch
  • Yi-Ming Shi
  • Christian Richter
  • Jose G Macia-Vicente
  • Harald Schwalbe
  • Marcel Kaiser
  • Till Opatz
  • Helge B Bode
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000485089200064&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.1021/acs.joc.9b01229
eISSN
1520-6904
Externe Identifier
  • Clarivate Analytics Document Solution ID: IW6LM
  • PubMed Identifier: 31409073
ISSN
0022-3263
Ausgabe der Veröffentlichung
17
Zeitschrift
JOURNAL OF ORGANIC CHEMISTRY
Paginierung
11203 - 11209
Datum der Veröffentlichung
2019
Status
Published
Titel
(±)-Alternarlactones A and B, Two Antiparasitic Alternariol-like Dimers from the Fungus <i>Alternaria alternata</i> P1210 Isolated from the Halophyte <i>Salicornia</i> sp.
Sub types
  • Article
Ausgabe der Zeitschrift
84

Data source: Web of Science (Lite)

Other metadata sources:
Autoren
  • Yan-Ni Shi
  • Stefan Pusch
  • Yi-Ming Shi
  • Christian Richter
  • Jose G Maciá-Vicente
  • Harald Schwalbe
  • Marcel Kaiser
  • Till Opatz
  • Helge B Bode
DOI
10.1021/acs.joc.9b01229
eISSN
1520-6904
ISSN
0022-3263
Ausgabe der Veröffentlichung
17
Zeitschrift
The Journal of Organic Chemistry
Sprache
en
Online publication date
2019
Paginierung
11203 - 11209
Datum der Veröffentlichung
2019
Status
Published
Herausgeber
American Chemical Society (ACS)
Herausgeber URL
http://dx.doi.org/10.1021/acs.joc.9b01229
Datum der Datenerfassung
2023
Titel
(±)-Alternarlactones A and B, Two Antiparasitic Alternariol-like Dimers from the Fungus <i>Alternaria alternata</i> P1210 Isolated from the Halophyte <i>Salicornia</i> sp.
Ausgabe der Zeitschrift
84

Data source: Crossref

Abstract
Two new dimeric compounds of the alternariol class, (±)-alternarlactones A (<b>1</b>) and B (<b>2</b>), were isolated along with 11 known compounds from the fungus <i>Alternaria alternata</i> P1210. Their structures were elucidated with the assistance of long-range HSQMBC to address inadequate cross-peaks in HMBC that result from the highly dense quaternary carbons, as well as theoretical calculations. All isolated altenuisol derivatives were screened for their antiparasitic activities, which provide a preliminary structure-activity relationship of this class of compounds against neglected tropical diseases.
Autoren
  • Yan-Ni Shi
  • Stefan Pusch
  • Yi-Ming Shi
  • Christian Richter
  • Jose G Maciá-Vicente
  • Harald Schwalbe
  • Marcel Kaiser
  • Till Opatz
  • Helge B Bode
DOI
10.1021/acs.joc.9b01229
eISSN
1520-6904
Externe Identifier
  • PubMed Identifier: 31409073
Funding acknowledgements
  • Deutsche Forschungsgemeinschaft: MA 7171/1-1
  • LOEWE-Centre for Translational Biodiversity Genomics:
  • Alexander von Humboldt-Stiftung:
Open access
false
ISSN
0022-3263
Ausgabe der Veröffentlichung
17
Zeitschrift
The Journal of organic chemistry
Schlüsselwörter
  • Alternaria
  • Lactones
  • Antiparasitic Agents
  • Dimerization
  • Salt-Tolerant Plants
Sprache
eng
Medium
Print-Electronic
Online publication date
2019
Paginierung
11203 - 11209
Datum der Veröffentlichung
2019
Status
Published
Datum der Datenerfassung
2019
Titel
(±)-Alternarlactones A and B, Two Antiparasitic Alternariol-like Dimers from the Fungus <i>Alternaria alternata</i> P1210 Isolated from the Halophyte <i>Salicornia</i> sp.
Sub types
  • Research Support, Non-U.S. Gov't
  • Journal Article
Ausgabe der Zeitschrift
84

Data source: Europe PubMed Central

Abstract
Two new dimeric compounds of the alternariol class, (±)-alternarlactones A (1) and B (2), were isolated along with 11 known compounds from the fungus Alternaria alternata P1210. Their structures were elucidated with the assistance of long-range HSQMBC to address inadequate cross-peaks in HMBC that result from the highly dense quaternary carbons, as well as theoretical calculations. All isolated altenuisol derivatives were screened for their antiparasitic activities, which provide a preliminary structure-activity relationship of this class of compounds against neglected tropical diseases.
Autoren
  • Yan-Ni Shi
  • Stefan Pusch
  • Yi-Ming Shi
  • Christian Richter
  • Jose G Maciá-Vicente
  • Harald Schwalbe
  • Marcel Kaiser
  • Till Opatz
  • Helge B Bode
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/31409073
DOI
10.1021/acs.joc.9b01229
eISSN
1520-6904
Ausgabe der Veröffentlichung
17
Zeitschrift
J Org Chem
Schlüsselwörter
  • Alternaria
  • Antiparasitic Agents
  • Dimerization
  • Lactones
  • Salt-Tolerant Plants
Sprache
eng
Country
United States
Paginierung
11203 - 11209
Datum der Veröffentlichung
2019
Status
Published
Datum, an dem der Datensatz öffentlich gemacht wurde
2020
Titel
(±)-Alternarlactones A and B, Two Antiparasitic Alternariol-like Dimers from the Fungus Alternaria alternata P1210 Isolated from the Halophyte Salicornia sp.
Sub types
  • Journal Article
  • Research Support, Non-U.S. Gov't
Ausgabe der Zeitschrift
84

Data source: PubMed

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