Luminescent TOP Nanosensors for Simultaneously Measuring Temperature, Oxygen, and pH at a Single Excitation Wavelength
- Publication type:
- Journal article
- Metadata:
-
- Autoren
- Cui Wang
- Sven Otto
- Matthias Dorn
- Katja Heinze
- Ute Resch-Genger
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000458220300095&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1021/acs.analchem.8b05060
- eISSN
- 1520-6882
- Externe Identifier
- Clarivate Analytics Document Solution ID: HK8DT
- PubMed Identifier: 30614676
- ISSN
- 0003-2700
- Ausgabe der Veröffentlichung
- 3
- Zeitschrift
- ANALYTICAL CHEMISTRY
- Paginierung
- 2337 - 2344
- Datum der Veröffentlichung
- 2019
- Status
- Published
- Titel
- Luminescent TOP Nanosensors for Simultaneously Measuring Temperature, Oxygen, and pH at a Single Excitation Wavelength
- Sub types
- Article
- Ausgabe der Zeitschrift
- 91
Data source: Web of Science (Lite)
- Other metadata sources:
-
- Autoren
- Cui Wang
- Sven Otto
- Matthias Dorn
- Katja Heinze
- Ute Resch-Genger
- DOI
- 10.1021/acs.analchem.8b05060
- eISSN
- 1520-6882
- ISSN
- 0003-2700
- Ausgabe der Veröffentlichung
- 3
- Zeitschrift
- Analytical Chemistry
- Sprache
- en
- Online publication date
- 2019
- Paginierung
- 2337 - 2344
- Datum der Veröffentlichung
- 2019
- Status
- Published
- Herausgeber
- American Chemical Society (ACS)
- Herausgeber URL
- http://dx.doi.org/10.1021/acs.analchem.8b05060
- Datum der Datenerfassung
- 2023
- Titel
- Luminescent TOP Nanosensors for Simultaneously Measuring Temperature, Oxygen, and pH at a Single Excitation Wavelength
- Ausgabe der Zeitschrift
- 91
Data source: Crossref
- Abstract
- Two nanosensors for simultaneous optical measurements of the bioanalytically and biologically relevant analytes temperature ("T"), oxygen ("O"), and pH ("P") have been designed. These "TOP" nanosensors are based on 100 nm-sized silica-coated polystyrene nanoparticles (PS-NPs) doped with a near-infrared emissive oxygen- and temperature-sensitive chromium(III) complex ([Cr(ddpd)<sub>2</sub>][BPh<sub>4</sub>]<sub>3</sub>, CrBPh<sub>4</sub>) and an inert reference dye (Nile Red, NR or 5,10,15,20-tetrakis(pentafluorophenyl) porphyrin, TFPP) and are covalently labeled with pH-sensitive fluorescein isothiocyanate (FITC). These emitters can be excited at the same wavelength and reveal spectrally distinguishable emission bands, allowing for ratiometric intensity-based and time-resolved studies in the visible and near-infrared wavelength region. Studies in PBS buffer solutions and in a model body liquid demonstrate the applicability of these nanosensors for the sensitive luminescence readout of TOP simultaneously at the same spatialposition.
- Addresses
- Federal Institute for Materials Research and Testing (BAM) , Richard-Willstätter-Strasse 11 , Berlin D-12489 , Germany.
- Autoren
- Cui Wang
- Sven Otto
- Matthias Dorn
- Katja Heinze
- Ute Resch-Genger
- DOI
- 10.1021/acs.analchem.8b05060
- eISSN
- 1520-6882
- Externe Identifier
- PubMed Identifier: 30614676
- Funding acknowledgements
- Deutsche Forschungsgemeinschaft: RE 1203/23- 1
- Johannes Gutenberg-Universit?t Mainz:
- Deutsche Forschungsgemeinschaft: GSC 266
- Deutsche Forschungsgemeinschaft: HE 2778/10-1
- Open access
- false
- ISSN
- 0003-2700
- Ausgabe der Veröffentlichung
- 3
- Zeitschrift
- Analytical chemistry
- Sprache
- eng
- Medium
- Print-Electronic
- Online publication date
- 2019
- Paginierung
- 2337 - 2344
- Datum der Veröffentlichung
- 2019
- Status
- Published
- Datum der Datenerfassung
- 2019
- Titel
- Luminescent TOP Nanosensors for Simultaneously Measuring Temperature, Oxygen, and pH at a Single Excitation Wavelength.
- Sub types
- Research Support, Non-U.S. Gov't
- Journal Article
- Ausgabe der Zeitschrift
- 91
Data source: Europe PubMed Central
- Abstract
- Two nanosensors for simultaneous optical measurements of the bioanalytically and biologically relevant analytes temperature ("T"), oxygen ("O"), and pH ("P") have been designed. These "TOP" nanosensors are based on 100 nm-sized silica-coated polystyrene nanoparticles (PS-NPs) doped with a near-infrared emissive oxygen- and temperature-sensitive chromium(III) complex ([Cr(ddpd)2][BPh4]3, CrBPh4) and an inert reference dye (Nile Red, NR or 5,10,15,20-tetrakis(pentafluorophenyl) porphyrin, TFPP) and are covalently labeled with pH-sensitive fluorescein isothiocyanate (FITC). These emitters can be excited at the same wavelength and reveal spectrally distinguishable emission bands, allowing for ratiometric intensity-based and time-resolved studies in the visible and near-infrared wavelength region. Studies in PBS buffer solutions and in a model body liquid demonstrate the applicability of these nanosensors for the sensitive luminescence readout of TOP simultaneously at the same spatialposition.
- Autoren
- Cui Wang
- Sven Otto
- Matthias Dorn
- Katja Heinze
- Ute Resch-Genger
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/30614676
- DOI
- 10.1021/acs.analchem.8b05060
- eISSN
- 1520-6882
- Ausgabe der Veröffentlichung
- 3
- Zeitschrift
- Anal Chem
- Sprache
- eng
- Country
- United States
- Paginierung
- 2337 - 2344
- Datum der Veröffentlichung
- 2019
- Status
- Published
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2020
- Titel
- Luminescent TOP Nanosensors for Simultaneously Measuring Temperature, Oxygen, and pH at a Single Excitation Wavelength.
- Sub types
- Journal Article
- Research Support, Non-U.S. Gov't
- Ausgabe der Zeitschrift
- 91
Data source: PubMed
- Beziehungen:
-