As Long as the Breath Lasts: In Utero Exposure to Ramadan and the Occurrence of Wheezing in Adulthood

Autoren

Fabienne Pradella
Reyn van Ewijk

DOI

10.1093/aje/kwy132

eISSN

1476-6256

ISSN

0002-9262

Ausgabe der Veröffentlichung

10

Zeitschrift

American Journal of Epidemiology

Sprache

en

Online publication date

2018

Paginierung

2100 - 2108

Datum der Veröffentlichung

2018

Status

Published

Herausgeber

Oxford University Press (OUP)

Herausgeber URL

http://dx.doi.org/10.1093/aje/kwy132

Datum der Datenerfassung

2019

Titel

As Long as the Breath Lasts: In Utero Exposure to Ramadan and the Occurrence of Wheezing in Adulthood

Ausgabe der Zeitschrift

187

Data source: Crossref

Abstract

While prenatal exposure to Ramadan has been shown to be negatively associated with general physical and mental health, studies on specific organs remain scarce. In this study, we explored whether Ramadan exposure during pregnancy affects the occurrence of wheezing, a main symptom of obstructive airway disease. Using data from the Indonesian Family Life Survey collected between 1997 and 2008 (waves 2-4), we compared wheezing occurrence among adult Muslims who had been in utero during Ramadan with that in adult Muslims who had not been in utero during Ramadan. Wheezing prevalence was higher among adult Muslims who had been in utero during Ramadan, independent of the pregnancy phase in which the exposure to Ramadan occurred. Moreover, this association tended to increase with age, being strongest among those aged about 45 years or older. This is in line with fetal programming theory, suggesting that impacts of in utero exposures often manifest only after reproductive age. Particularly strong associations were detected for smokers. The respiratory system of prenatally exposed Muslims thus seems to perform worse in mitigating later ex utero harmful influences such as smoking. This study suggests that exposure to Ramadan during pregnancy may have lasting consequences for adult lung functionality.

Addresses

Gutenberg School of Management and Economics, Faculty of Law and Economics, Johannes Gutenberg University Mainz, Mainz, Germany.

Autoren

Fabienne Pradella
Reyn van Ewijk

DOI

10.1093/aje/kwy132

eISSN

1476-6256

Externe Identifier

PubMed Identifier: 29961865

Funding acknowledgements

German Research Foundation: 260639091

Open access

false

ISSN

0002-9262

Ausgabe der Veröffentlichung

10

Zeitschrift

American journal of epidemiology

Schlüsselwörter

Humans
Prenatal Exposure Delayed Effects
Respiratory Sounds
Fasting
Prevalence
Longitudinal Studies
Smoking
Pregnancy
Islam
Adolescent
Adult
Middle Aged
Indonesia
Female
Male
Maternal Nutritional Physiological Phenomena
Young Adult

Sprache

eng

Medium

Print

Paginierung

2100 - 2108

Datum der Veröffentlichung

2018

Status

Published

Datum der Datenerfassung

2018

Titel

As Long as the Breath Lasts: In Utero Exposure to Ramadan and the Occurrence of Wheezing in Adulthood.

Sub types

Research Support, Non-U.S. Gov't
Journal Article

Ausgabe der Zeitschrift

187

Data source: Europe PubMed Central

Abstract

While prenatal exposure to Ramadan has been shown to be negatively associated with general physical and mental health, studies on specific organs remain scarce. In this study, we explored whether Ramadan exposure during pregnancy affects the occurrence of wheezing, a main symptom of obstructive airway disease. Using data from the Indonesian Family Life Survey collected between 1997 and 2008 (waves 2-4), we compared wheezing occurrence among adult Muslims who had been in utero during Ramadan with that in adult Muslims who had not been in utero during Ramadan. Wheezing prevalence was higher among adult Muslims who had been in utero during Ramadan, independent of the pregnancy phase in which the exposure to Ramadan occurred. Moreover, this association tended to increase with age, being strongest among those aged about 45 years or older. This is in line with fetal programming theory, suggesting that impacts of in utero exposures often manifest only after reproductive age. Particularly strong associations were detected for smokers. The respiratory system of prenatally exposed Muslims thus seems to perform worse in mitigating later ex utero harmful influences such as smoking. This study suggests that exposure to Ramadan during pregnancy may have lasting consequences for adult lung functionality.

Date of acceptance

2018

Autoren

Fabienne Pradella
Reyn van Ewijk

Autoren-URL

https://www.ncbi.nlm.nih.gov/pubmed/29961865

DOI

10.1093/aje/kwy132

eISSN

1476-6256

Ausgabe der Veröffentlichung

10

Zeitschrift

Am J Epidemiol

Schlüsselwörter

Adolescent
Adult
Fasting
Female
Humans
Indonesia
Islam
Longitudinal Studies
Male
Maternal Nutritional Physiological Phenomena
Middle Aged
Pregnancy
Prenatal Exposure Delayed Effects
Prevalence
Respiratory Sounds
Smoking
Young Adult

Sprache

eng

Country

United States

Paginierung

2100 - 2108

PII

5046841

Datum der Veröffentlichung

2018

Status

Published

Datum, an dem der Datensatz öffentlich gemacht wurde

2019

Titel

As Long as the Breath Lasts: In Utero Exposure to Ramadan and the Occurrence of Wheezing in Adulthood.

Sub types

Journal Article
Research Support, Non-U.S. Gov't

Ausgabe der Zeitschrift

187

Data source: PubMed

As Long as the Breath Lasts: In Utero Exposure to Ramadan and the Occurrence of Wheezing in Adulthood

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