Thyroid surgery in children and young adults: potential overtreatment and complications
- Publication type:
- Journal article
- Metadata:
-
- Abstract
- <jats:title>Abstract</jats:title><jats:sec> <jats:title>Purpose</jats:title> <jats:p>Thyroid nodules in the pediatric population are more frequently associated with malignant thyroid disease than in adult cohorts. Yet, there is a potential risk of surgical overtreatment. With this single center study, an analysis of potential overtreatment for suspected malignant thyroid disease in children and young adults was aimed for.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>In a period from 2005 to 2018, 155 thyroid operations in children and young adults performed at the University Medical Center Mainz, Germany, were analyzed (patient age 3–20 years, 117 female). Cases were categorized for preoperative diagnosis: non-malignant (group I, <jats:italic>n</jats:italic> = 45) and malignant thyroid disease (group II, <jats:italic>n</jats:italic> = 110). Postoperative parameters (histology, complication rates) were assessed and compared between groups.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>91.1% of group I were histologically benign. 44.5% of group II harbored malignancy. Permanent hypoparathyroidism was documented in group I (2.7%) and in group II (1.4%, <jats:italic>p</jats:italic> = 1.000). Wound infections were absent in group I but observed in group II (0.9%, p = 1.000). Transient vocal cord palsy was recorded only in group I (2.3%, 2/85 vs. 0/177 nerves at risk, <jats:italic>p</jats:italic> = 0.104). Permanent vocal cord palsies were absent.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusion</jats:title> <jats:p>Preoperative diagnoses were correct in over 90% of group I and in nearly 45% of group II. The high proportion of carcinomas in group II ruled out the issue of potential overtreatment. The risk of severe postoperative complications was equally low in both patient groups.</jats:p> </jats:sec>
- Autoren
- Julia I Staubitz
- Julia Bode
- Alicia Poplawski
- Felix Watzka
- Joachim Pohlenz
- Hauke Lang
- Thomas J Musholt
- DOI
- 10.1007/s00423-020-01896-x
- eISSN
- 1435-2451
- ISSN
- 1435-2443
- Ausgabe der Veröffentlichung
- 4
- Zeitschrift
- Langenbeck's Archives of Surgery
- Sprache
- en
- Online publication date
- 2020
- Paginierung
- 451 - 460
- Datum der Veröffentlichung
- 2020
- Status
- Published
- Herausgeber
- Springer Science and Business Media LLC
- Herausgeber URL
- http://dx.doi.org/10.1007/s00423-020-01896-x
- Datum der Datenerfassung
- 2021
- Titel
- Thyroid surgery in children and young adults: potential overtreatment and complications
- Ausgabe der Zeitschrift
- 405
Data source: Crossref
- Other metadata sources:
-
- Author's licence
- CC-BY
- Autoren
- Julia I Staubitz
- Julia Bode
- Alicia Poplawski
- Felix Watzka
- Joachim Pohlenz
- Hauke Lang
- Thomas J Musholt
- Hosting institution
- Universitätsbibliothek Mainz
- Sammlungen
- JGU-Publikationen
- Resource version
- Published version
- DOI
- 10.1007/s00423-020-01896-x
- File(s) embargoed
- false
- Open access
- true
- ISSN
- 1435-2451
- Zeitschrift
- Langenbeck's archives of surgery
- Schlüsselwörter
- 610 Medizin
- 610 Medical sciences
- Sprache
- eng
- Open access status
- Open Access
- Paginierung
- 451 - 460
- Datum der Veröffentlichung
- 2020
- Public URL
- https://openscience.ub.uni-mainz.de/handle/20.500.12030/5924
- Herausgeber
- Springer
- Herausgeber URL
- https://doi.org/10.1007/s00423-020-01896-x
- Datum der Datenerfassung
- 2021
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2021
- Zugang
- Public
- Titel
- Thyroid surgery in children and young adults : potential overtreatment and complications
- Ausgabe der Zeitschrift
- 405
Files
staubitz_julia-thyroid_surger-20210514091924665.pdf
Data source: OPENSCIENCE.UB